I contend that Money has acquired a character, a personality, if you like. So there you are, you have Mr. and Mrs. Average on the street, and then there is Money. It is best to keep Money otherwise anonymous, for it has become uppity enough. In the old days, people would say that “money talks” and that inference has been made fact. Nowadays, Money makes a dialogue to fit its own ends and Money knows where it is going, with whom it is having dinner tonight, whom it is going to embarrass due to its immediate absence, and the person or company it is going to ruin in the morning.

Money, you might say, has got Greece on the skids. It is not really the fault of Greece or Grecians in general, because, you see, Money has become sly, altogether its own boss.

Nevertheless, despite the awful Cloud of Unknowing hovering over Athens, the Greeks of our acquaintance have been generous to a fault. We have been offered many a meze (a small plate of olives, feta, sausage, etc.), coffee or glass of ouzo free of charge. There has been a bon vivant air to our relationships, but we are convinced that due to the rather cavalier handling of their monetary means, these jolly persons do not wish to have a mainland psyche.

Who was it who said that “only a millionaire can afford to be a communist”? Never mind, the notion is perfectly applicable to Greece and its very nice people. It could mean that either they are all transcended souls and have seen something that we have not, or simply don’t give two figs for the idea of poverty. This is true on the islands, that is! Athens is another matter altogether.

In much the same way that there are countries in which poverty means a less strenuous existence than in some others. (Being poor in Austria, for example, is bearable. Poverty in some other countries, which we do not name, would be quite horrid.) Life for the Greek islanders is obviously less affected than life for those living in Athens. In the islands in other words, Money has none of the packed dependents that a metropolis offers to exert its lack of presence. Athens may well be the seat of government, but the islands seem to require little governing. One can’t shake off the feeling that Money has made itself essential to the running of a financial capital and nowhere else, because that is what financial capitals are for. See? The capital cities of this world are all a home-from-home for Money. We shudder at the thought of Brussels, which obviously needs paying for, going the same way.

My wife and I have decided to have no truck with money (we have de-capitalised it for a start). Should money stray our way, we will toss it into a corner and let it sulk for a bit; we may send it to a Third World country, which is where it belongs, but we will NOT go out and spend it. Moreover, we will excommunicate it from our feelings; we will not thrill at the thought of it; we will not indulge in sprees, thereby refusing to have a good time on the strength of money. Above all, we will resist the attraction of what money can buy. (There is a lovely little chrome-vanadium ratchet-spanner set that keeps beckoning to me when I pass its shop window.) We have pierced this monetary fog of collusion with the searchlight of our mind. We may want something but we rarely need it. That may sound like a pretty ordinary thought process, but one does require a certain resolve to carry the cross. Thus, down with glitter, down with sell, and back to the village life that serves us well.

The lady (one’s financially bemused wife) is a bit unsure of all this, despite the fact that she can circulate through a supermarket (“they always give me a headache”) and emerge with a full trolley in ten minutes flat, while one is still wrestling with the urge to buy a needless gadget.

The answer is obvious! We must drop out! We may be in the world but we will not be of it! We will say “get thee behind me – thou shalt follow and not lead.”

But can one avoid money? The machine one writes on was purchased with money. We may feel smug and contend that it is paid for and that’s that! But money has induced some manufacturers to produce goods that are set to implode within three years. Thus, money needs to circulate to feel OK, to do the rounds, check out the joints and the venues, get fluttered every so often, muscle in on things and throw its weight about, get turned into cheques and then get cashed, get wired somewhere, get bought and sold. My goodness, can one really buy and sell money? If so, what does one use in the process of buying and selling? A popular brand of beer sold in Greece is called Mythos. Go figure!

Lawrence Brazier is a writer living with his wife in rural Austria. His main interest is mystical experience.

Where am I?

There are 46 chromosomes in your body, carrying 20-25 thousand genes. Chromosomes and the genes they contain shape the genetic memory of a human being. Genes can contain hundreds of features, and these are revealed over time. For instance, you do not have any teeth when you are a newborn, but the time when you will get your teeth is encoded into your genetic memory. Once genes receive the action command, teeth start to emerge.

There are hundreds of genes located on chromosomes, all the way from the chromosome number 1 and 2, to chromosome number 46. For example, there are around three thousand genes found on chromosome number 1. The Y chromosome, in charge of male development, only contains 125 genes. A distinct address (locus) for each gene on the chromosomes is recorded. If you ask about the address of the fibrillin gene that synthesizes me, it is 15q 21.1, i.e., 15th Avenue, Long arm street, 21st pl, Number 1.

In other words my residing address is the 1st subband of the 1st band of the 2nd region located at the long arm of chromosome number 15. We are three siblings, known as fibrillin1, fibrillin2 and fibrillin3.

We stretch and relax like an arch. We can expand and tighten like an inflated balloon and then return to our previous state. If by an error, we happen to fail to restore ourselves after inflation, the tissue’s architecture gets deformed and expanded fibers cannot regain their original shape anymore. When observed in veins, this situation is called an aneurysm. The frequency of this disease is approximately one in ten thousand, which is also called ballooning. That said, my flexing is necessary. Veins flex so that the blood pumping through them doesn’t cause any turbulence, as it would otherwise be during a vacuum occurring inside metal water pipes. Flexible sportsmen who do acrobatic moves do not compare with me. I can bend, curve, flex, relax and constrict, inflate, deflate and transform like elastic, from one shape to another, for your health and overall convenience – all because of the wondrous features granted to my nature.

What kind of a fiber am I?

I provide structural support for the fabrication of elastic fibers in the connective tissue as a protein synthesized according to the code of the fibrillin gene. In case of my failure or absence, weaknesses occur, especially in the connective tissues of organs that are rich in elastic fibers, such as the aorta, lungs, and eye balls. The iris (the colored part of the eye), pupil, and eye lens display changes in accordance with levels of light or distance of objects observed. These changes are controlled perfectly according to my work, and humans often don’t even notice this. We also help the eye lens constrict and relax. It can be understood that we are such a great blessing granted for your service. Of course, if we tried to count all the blessings we’ve been given, and never even consider, it would be impossible!

My weight is 350 kilo daltons. A Dalton is an atomic mass unit approximately equal to one hydrogen atoms’ mass, which is 1.66×10-24. I consist of 2.871 amino acids. I am formed by the sequential arrangement of 20 amino acids that exist in your body as the smallest unit of proteins. We bind each other to become 10-12 nanometers wide microfibers as the result of a process called polymerization that brings loops of a protein chain together. These microfibers are brought together with the elastin protein that provides elasticity in our body. The system that we form with elastic fibrils constantly serves the body’s blood vessels, primarily the vessels located in your eyes, heart, and many of your tissues, such as your skin and nerves.

What do I do? We fulfill commands that are requested from us in many tissues and organs, without any flaws. Scientists call us the wonderful building blocks of the body’s architecture. We can extend twice as much of our length. We are always on task: while you are breathing, when your heart is pumping blood and your stomach is digesting food, or the moment you are gazing at nature with your eyes. We are given the duty to prevent many organs from tearing, including the heart, lungs, stomach, and blood vessels. One of the places I work most frequently is the aorta, the body’s major artery. Your heart beats approximately a hundred thousand times a day. A high level of pressure develops in the arteries during the pumping process. You would suffer greatly without the help of our elastic fibers. Blood vessels would rupture, ending your life. This high pressure is tolerated only through the expansion of the vessel’s diameter without any decrease in length of the artery. This diameter regulation is designed so wondrously that blood flow remains the same; no shaking or waves are observed. This diameter control happens via the fibrillin protein located inside the vessel.

I also play a role in the vitality and tension of your skin. Skin is essentially a dense fibrous connective tissue composed of a protein called collagen. I am also one of the main elements of this connective tissue. As you age, this layer starts to dry and has lesser fibrous proteins; therefore, as fibers decrease, so does my tension, and I start to wrinkle. Elderly people do not like getting wrinkly, but this is your fate. Whatever you do, I will also age and die.

I cannot go without pressing this important issue: Staying under the sun for a long time degrades me. If done properly, sun light is useful for skin. But solar radiation damages the live tissues and organs. This radiation is an effective factor both in degradation of protein structures, and the formation of varicose veins and skin damage. It is reported in various sources that exposure to sun rays leads to alterations in the genetic material of skin. Ultraviolet rays speed up the degradation of skin. In medical language, this is called oxidation via free radicals. Please do not burn us and yourself while sunbathing. Even if you do not care for yourselves, you should still be considerate of us. If you say that sunbathing both helps, with vitamin D synthesis and reducing the risk of osteoporosis, I would like to remind you that for the vitamin D synthesis of skin, it is sufficient to expose your hands, feet and face to the sun.

How is life without me?

Though we were wisely designed, sometimes, you are tested by certain diseases in which we are not present. Absence, as they say, makes the heart grow fonder!

Life without me is unbearable. I could give a couple of examples, should you like. If I was not created, your skin would not be flexible. You wouldn’t be able to control your eye lenses. Your aorta would not be flexible and your heart, which beats thousands of times a day, would be torn under the high pressure in a short amount of time. Major problems would occur with the development of your stomach, lungs, and other organs.

I also have a significant job keeping TGF-Beta (which helps cells grow) function under control. To give you an idea of how important this is, imagine your communication system turned upside down. Now imagine how complicated are the communication systems connecting billions of people around the world, how a mess it would be when they are out of service. These are nothing when compared to the human body. There are 100 trillion cells in the human body, communicating with each other instantaneously. A cellular community that is fifteen thousand times more crowded than the earth’s population communicates via small molecules, like us. Cellular proliferation and tissue differentiation would fail if cells failed to communicate. The full spoon of food in your hand would not end in your mouth but maybe in your ear or your eyes.

If a mutation happens with the Fibrillin-1 gene, Marfan syndrome can occur. This disease, which was defined in the 1800s, is named after its discoverer. The frequency of this disease is one in five thousand. One of the major lethal consequences of Marfan syndrome is an aorta tear. This is in addition to many problems with the eyes, skeleton, and cardio-vascular systems. Many of the patients die in their 30s or 40s because of the flaws in the cardio-vascular system. Of course, death may occur at any age because of an aorta rupture. 14% of the patients with Marfan syndrome display chronic obstructive pulmonary disease (COPD), which is associated with breathing problems, because the integrity of lung tissue is compromised. Another disease I help prevent is called Ektopia lentis, in which the eye lens is displaced from its original position. Normally, I help eye functioning. When my fibers relax or constrict, depending on light, I help the eye to relax, enabling both near and far sightedness. With Ektopia lentis, anomalies on the front vestibule of the eye, a high degree of myopia, and retina damage occur.

If overproduced, I can cause another problem with the eye, called exfoliation syndrome. This is when fibrous connective tissue, like me, accumulates in the eye – it’s commonly called glaucoma, or ocular hypertension. In some people, as they age, a fibrous material like hair dandruff collects on the eye lens. This material, dislocated by movements of the iris, blocks the drainage channels that discharge the intraocular fluid. Eye pressure increases as the result of failed drainage. As you see, I am not a problem when I am synthesized normally, but can be trouble if over produced! My final request from you!

You have seen our amazing works and complicated functions. Therefore, please remember me and my friends. Please do not ignore our efforts and activities. Be grateful for the blessings provided through us, even if you can’t see them. And take care of us, please – don’t get carried away with too much tanning!

Dream, Believe, Fly. These three words have a ring, a truth, a purity. As an author of books for teen readers, I gave these three words to one of my characters, and these three words became her mantra. She was sixteen; I am more. The motto works for both of us. My character had those words tattooed onto her skin; I have them tattooed into my soul. Dream. Believe. Fly.

The first step to achieving is to dream. You need to see, you need to dream, you need to believe. Faith and fervor result in the necessary work, and the work gives you wings. The wind beneath those wings is the dream, the belief, the need to achieve.

We are given one life. Some of us live soft; some live hard. Some laugh a lot; some cry. Some are brave; some are not. Some live many years; some live few. At the age of fifty-five, I’ve seen many friends leave this earth, and I’ve learned that we need to seize not only the moment, but our dreams. We need to seize our dreams, grab onto them, and never forget what we hope to accomplish in this world. We need to seize first, then to believe. We need to believe with all of our hearts, with all of our minds, with all of our very beings. We are each instilled with the magic to make things happen. We are resilient and we are strong and we have the power inside, if only we dream and we believe that we can indeed fly.

I’ve wanted to write ever since I can remember. My first memory of elementary school is that of the library, and of a pink Mary Poppins book that I reached up to pull from the shelf. Mary Poppins could fly, and this much I believed: So could I.

It would be many years, though, before I got my wings. There would be hardships and hurt, suffering and struggles. There would be days of hard work, and nights of worry. There would be dark nights when I could not see the stars; days when I tried to believe that life might get easier with time.

“When a man can observe himself suffering and is able, later, to describe what he’s gone through, it means he was born for literature.” A writer named Edouard Bourdet said that in 1927. Many years later, those words still speak to this writer’s soul.

1989 was a rough year. I was 31 years old, and my motto at that time might have been “Hang in there.” I was hit by a drunk driver in July. He left me by the roadside with injuries, a demolished car, and a shattered faith in mankind. He went to jail; I went home to heal.

Two months later, my stepson’s biological mother deposited him on our doorstep. He was six years old, and all he had in the world was a trash bag stuffed with his earthly possessions. He awakened sobbing every night. With my own six-year-old son from a previous marriage, I couldn’t comprehend how a mother’s heart could be so cold.

Two months after my stepson came to us, I unexpectedly became pregnant. I still had no car, and was undergoing treatment for persistent neck and back injuries incurred by the accident. We were poor. My stepson was aching and confused. So was I. Hang in there. Hang in there hang in there hang in there.

In the middle of the pregnancy, I contracted Fifth Disease, a form of the measles. There was an outbreak in the elementary schools of our area, and the medical community was unsure as to the effects of the illness in pregnant women. I was sent for a level two ultrasound, and told by the doctors that I could be “cautiously optimistic” for a healthy baby. However, I’d need a weekly ultrasound. If the fetus contracted the disease or showed signs of anemia, it would be necessary to undergo a blood transfusion in utero. The risks, I was told, were stillbirth and miscarriage. Oh, please, please. Hang in there.

On the day before our baby was due, my husband John came home from work, weeping. It was August of 1990, and the Gulf War and recession had resulted in a permanent lay-off from his longtime construction job. It was the first (and only) time I saw him cry. His heart was broken.

Our son was born: a perfectly healthy and beautiful baby boy. We were ecstatic, despite the fact that John didn’t have a job and we were living in a cramped mobile home with three children: his, mine, and ours.

“Maybe I should get a real job,” I said. “Give up this crazy dream of writing books.” I was an established newspaper and magazine writer, but had been attempting futilely to break into the competitive world of children’s books.

“Keep at it,” John said. “Don’t give up.” Don’t give up. Another three words to grasp onto. So I didn’t. I didn’t give up. I stayed home and wrote, raising our children and grasping tight to my hopes. I prayed for the strength to continue writing despite the obstacles and staggering odds. Don’t give up. Hang in there. Don’t give up.

Several weeks after our son Zach was born, John saw an ad in a local paper: “Old Barn: Free For The Taking-Down.”

John took the barn apart, piece-by-piece, and found that there was a market for the materials. The boards and beams, windows and doors and weather vanes were all sold. The barn would live on for another hundred years, in a hundred different places. It was

the beginning of John’s own business, but we still didn’t have much money. One writer and one self-employed Barn Saver plus three children is an equation that doesn’t always equal promptly-paid bills. Don’t give up. Hang in there.

When Zach was two months old, I began writing a novel for pre-teen children. Working on an ancient and clattering typewriter, I used the kitchen table for my desk. I plugged away on the typewriter as Zach dozed contentedly in his swing. Through the window of our mobile home, I could see the green Welsh Mountain of Pennsylvania. This mountain would be the setting of the book. The main character, Maizie, was a girl who’d been abandoned by her mother. She was hurting. Maizie had lots of wishes, but life was rough. I knew: I’d used bits and pieces of my own. But still, Maizie had hope. Someday, somehow, everything would be okay. Don’t give up. Hang in there.

The book Maizie would be published five years later, in 1995. In the meanwhile, I wrote a picture book based on John’s work of dismantling and recycling old barns. The book – Barn Savers – was published in 1999 and was honored by the American Library Association’s Booklist Journal by being named Top Of The List, Best Picture Book of 1999. It was also lauded as a Notable Book in the Language Arts by the National Council of Teachers of English, as well as short-listed for the Bill Martin Jr. Picture Book Award in Kansas and the Keystone State Reading award. A mention of the book appeared in the pages of People Magazine.

Since then, I’ve written about twenty more books. I went back to college at the age of fifty, and earned an MFA in Writing. I got to travel to Italy, because of my writing. I taught on cruise ships, and I taught in a medieval castle on a hilltop in Tuscany. I was honored in England in 2012 with a short story prize, and I got to travel to the U.K. for the first time, staying in the dorms of Oxford University. Dream, Believe, Fly.

Somewhere around the time that I changed from forty-nine to fifty, somewhere around the time that I applied to Vermont College and was accepted, that was the time that I changed my motto for life. I still believe in “Hang In There” and “Don’t Give Up.” But those words never held the power, the faith, the magic that my new motto does.

I had to get a student loan in order to go to school, and that was scary. I kept repeating my motto, though, as I waded through the mounds of paperwork and forms and red tape. “Dream. Believe. Fly. You are Linda Oatman High and you love to write. Dream, believe, fly. You only get one life. Now is the time. Dreambelievefly.”

Our youngest son went through some struggles in his teenage years. We got through them. He’s still finding his path in life, at the age of 23. As long as he dreams, as long as he believes … he will indeed fly.

The kids are now grown, and I’m on my way to growing old. I’m fifty-five. I love my life. It’s hard at times; it’s fun at others. But it’s always mine, and we only get one life.

I’m now a grandmother, and I hope to instill the things that I’ve learned in my grandchildren. I hope that they find the strength and the courage and the faith to dream. I pray that they believe.

And I know, I know, I know in my soul … they will fly.

Linda Oatman High is an author/playwright/poet/journalist (www.lindaoatmanhigh.com) who lives in Lancaster County, PA and teaches everywhere.

Some insight for leaves

Leaves are in charge of respiration in plants. They consist of the main mechanism producing food for plants, using sunlight via photosynthesis through which food for many more organisms, animals, and humans are provided. Having been assigned to convert solar energy to food, which they’ve been doing for millions, perhaps billions, of years, plants have been a significant instrument for sustaining life on or planet. It is as if plants turn their leaves upward in prayer to ask for food on behalf of all living things.

Morphology of a leaf

Leaves are composed of three sections: the base, blade, and petiole. The blade is the most important part of the leaf; it is wide and flat. The exact shape of leaves vary according to climate, geographical conditions, life span and risk of consumption by other organisms. In tropical climates, the blade is often very wide. In drier climates, it is usually smaller, in order to reduce water loss.

Leaves of some plants undergo a transformation called “metamorphosis” to fulfill different tasks. For example, some leaves have a thorny shape and protect the plant form herbivorous animals. Some leaves are designed to store water, and some are converted into a trap in order to capture insects to nourish the plant.

On the cross section of a leaf, one can observe that four layers constitute the inner part. The first one is the epidermis, which covers the leaf from top to bottom. This layer protects the leaf against external elements and is lined with a waterproof, waxy substance.

The palisade parenchyma is located on the upper side of the inner tissue and it houses chloroplast rich cells, which are lined up densely and carry out photosynthesis. The spongy layer under the palisade tissue forms the intercellular air spaces and this layer is responsible for the respiration of the plant.

For photosynthesis to occur, the leaf needs to receive the maximum amount of sunlight. The sun must hit the leaf at a perpendicular angle; thus, the leaf must be amply wide and must sit level. Because the sun hits different latitudes at different angles, plants have branches of different lengths facing different directions, and leaves have different curvatures. Furthermore, leaves are also lined up in a way so as not to block the sun’s rays. For this to happen, it is required for the leaf base to be thin and the leaves to be lined up in a spiral fashion that enables both lower and higher ones to harvest sunlight in the most efficient way. This type of arrangement exemplifies the golden ratio, which is observed among many structures in nature.

Each leaf sprouts at an angle of either 222.5 or 137.5, derived from division of 360 degrees, from the previous leaf under. This spiral leaf growth provides them with the most suitable place to harvest sunlight maximally. This way the gaps around branches are minimized and a maximum number of leaves is positioned without reducing the light capture capacity of the plant.

Seasons and leaves

Plants work like factories during spring and summer, producing a great deal of food through photosynthesis. Some of these foods help the plant grow and some are stored as starch for winter. With the onset of autumn, a majority of plants outside tropical zones go through hibernation, like many organisms do, and enter a dormant period. In order for plants, like trees and bushes, to survive the cold, their leaves are shed to minimize their surface area and conserve energy. Perennial green plants lose their aerial parts, too, including stems and leaves, and hibernate underground as roots, bulbs, and tubers. They sprout back from their roots once spring brings warmer weather.

Many leaves begin to fade and fall once autumn arrives. The leaves of some hardy plants – like cypress, pine, and spruce trees – continue to function through winter. In some of these trees, like the bay tree and the Indian sandalwood, there are protective layers covering the leaves against the cold. Other leaves, like pine needles, are created in a spiny shape to resist the cold.

Colors of autumn

Leaves seem green during the spring and summer months because the chlorophyll found in them absorbs all wavelengths other than green. The other major pigments found in leaves are carotene (orange) and xanthophylls (yellow). These two pigments are the most common pigments in nature.

As autumn approaches, and photosynthesis begins to end, chlorophyll starts to degrade and the other pigments begin to show. Thus, leaves turn yellow and bright red.

As the weather gets colder, the chloroplasts that are near the leaf’s bottom are broken apart, and sugar levels begin to elevate. The sugars produced during this season accumulate in the leaves day by day due to lower photosynthetic speed and reduced transportation to other parts of the plant. These sugars are converted into anthocyanins. At first, leaves appear yellow. A couple weeks before they fall, most leaves shift from yellow to red. Under abundant sunlight, due to concentrated anthocyanins, leaves seem brighter and more colorful – and thus red. Once the live tissues die completely, all leaves turn brown. This is due to the high concentration of tannin.

Leaf color varies not only because of plant genetics and external factors, but also because of climate. Temperature, humidity, soil composition, and levels of sun exposure all affect color. There is a higher degree of color change in the leaves of trees that grow in lower temperatures.

The composition of soil plays a major role in the color of leaves. Leaves that turn yellow early indicate a nitrogen shortage; on the other hand, the presence of a strong red color indicates very acidic soil. A high alkaline ratio is present in places where leaves are purple.

Walking among fallen leaves and the colorful scenery in a forest in autumn can trigger unique emotions. Depending on the psychological state of a person, the colors of autumn sometimes remind us about the briefness of this world, but they can also hint at the infinite life to come.

The motifs and patterns of leaves

Receiving sufficient sunlight is a significant matter for leaves. Therefore, they are created differently. No two plant leaves are the same.

Some of the leaves are simple and some are compounds. According to their arrangements, opposite, alternate, whorled, and rowed forms exist. Leaf blades can be ovals, kidneys, triangles, or even hearts. Edges can be smooth, serrated, toothed, or lobed. Leaf veins can also have many different motifs.

Each plant species has its own leaf motif. The alfalfa leaf has a triple pattern of specific angles; walnut leaves have an opposite arrangement of eight to ten. A hand-like motif, like the fingers of a praying hand, formed of seven leaves, can be observed on chestnut trees.

In a world of relativities, however, 100 is not immune to varying perceptions. For the young, it is as far as the horizon; for the old, it is as if just around the corner. Maybe it’s not the most pleasing age to aspire to. Some years feel like a century by themselves, especially when so many events are compressed into them. 100, for an institution, is a signpost that proves a level of maturity, establishment, and depth of foundation. But 100 is also a promise for the future.

Here comes the 100th issue of The Fountain (hence you now know why so many words on the number 100!). For a daily newspaper or a weekly magazine, the 100th issue is not the biggest target to strive for. But for a periodical like The Fountain – which publishes serious content on various disciplines while trying to maintain a perspective and level of discourse about issues that pertain to all fellow human citizens, the brothers and sisters of a global home – 100 is not an insignificant number to reach. For over two decades, The Fountain has always chosen to stay above the fray of day-to-day events, temporary politics, or issues that are irrelevant to others. We have been selective in what we publish and tried to ensure content of universal appeal yet with an awareness of differences and respect for local diversities in color, language, culture, and faith.

In this 100th issue, we invite our dedicated readers to write on their takes on The Fountain. Write in 100 words on what The Fountain stands for in your life. What do you understand of its message? How do you think it is different than another publication? Write your life philosophy based on where you stand vis-à-vis The Fountain’s message. Do your best to reach or limit your writing to 100 words, but your reflection does not have to be the exact number. There will be surprise gifts and recognition for participants. Follow our website and social media announcements regarding the deadline and how to submit your work.

In this issue, we continue with Dr. Beecher’s second part on nation and the construction of self identity, the first part of which received positive feedback in the previous issue. His work is complemented by Dr. Kavi’s research on identity and its relationship with religion and culture. Dr. Aydin’s article on memetics is an additional contribution to this issue laying down some perspective on questions such as “How does the mind work? How do humans learn and develop? How does culture form and transfer to future generations?” The lead article sweeps over these issues with a more profoundly human twist on human life, which we are obliged to travel” for the sake of finding ourselves and realizing our true essence. As The Fountain hits 100, it’s a good time to reflect on where we all are in that journey.

Interfaith dialogue has been a very controversial issue and there have been a lot of discussions about it: its necessity, rationale, and success (Kurucan 2006). These questions have made it obvious that people are not aware of the real meaning of interfaith dialogue.

Perelman and Olbrechts- Tyteca (1969) explain dialogue as follows: “… (it) is not supposed to be a debate … but rather a discussion in which the interlocutors search honestly and without bias for the best solution to a controversial problem” (196, 37). Related to this description, Gulen (2000) describes interfaith dialogue as “… seek(ing) to realize religion’s basic oneness and unity, and the universality of belief. Religion embraces all beliefs and races in brotherhood, and exalts love, respect, tolerance, forgiveness, mercy, human rights, peace, brotherhood, and freedom via its Prophets” (The Fountain, September 2000). These descriptions bring out another question: how useful and beneficial can interfaith dialogue be in solving problems?

Interfaith dialogue does not aim to change the ideas of people about their religions or faiths, but seeks to find common ground between religions, to focus on communities, and through an emphasis on harmony and peace, find solutions to many of our common problems. In fact, one of the reasons for interfaith dialogue is to “provide an atmosphere of freedom” (Kurucan 2006, 17).

Another major proponent of dialogue was Seyyed Hossein Nasr, a professor of Islamic studies at George Washington University. When he visited the Vatican in 1977 in a delegation, Nasr highlighted five areas that Christianity and Islam can work together to make the world better. These five areas are “dangers of modern technocracy and ecological ruin, energy crises, youth problems and decadence of morality and faith” (Kot 2009). In addition, Rev. Allman states, “The ability to discuss our religious and cultural differences is more than an ‘extra-curricular activity’; it is a skill which is vital for participants in democracy, especially a democratic society such as ours, which is filled with people whose differences are deep and complex” (The Network, 1999).

These statements show the importance of interfaith dialogue for the improvement of humanity and the goodwill of societies. Pinto (2003) highlights the role of interfaith dialogue in today’s society as “…an inevitable fact of our being-with-other-faiths.”

In connection to this, Swidler et al. (2007) state that, “In the past, during the age of divergence, we could live in isolation from each other; we could ignore each other. Now, in the age of convergence, we are forced to live in one world. We increasingly live in a global village” (Stress added, p.1).

Today most of the common reasons for dispute between religions, or between people of different religions, are that they do not understand one another’s beliefs or ideas (Baum 2011). Interfaith dialogue meetings, panels, conferences help these misconceptions and unfamiliarity disappear. And the result of such dialogues can be tremendous. As Smock states, “… when two or more faiths come together to explore or promote the possibility of peace, the effects can be especially potent” (viii).

The benefits of interfaith dialogue are obvious but still it is not an easy work. Once again, Smock (2002) highlights that “interfaith dialogue is a difficult, often painful endeavor” (viii). There are some prerequisites for interfaith dialogue to be successful. Swidler (2003) categorizes them as:

“1) an openness to learn from the other. 2) knowledge of one’s own tradition. 3) a similarly disposed and knowledgeable dialogue partner from the other tradition” (p. 12).

The importance of each prerequisite will be explained in detailed below.

Ingredients for a successful interfaith dialogue meeting

1) The most important component of interfaith dialogue is to remember the real meaning of dialogue. It is a two-way discussion that requires respect and understanding. This component may seem very simple to understand but it is very easy to forget. Swidler (2007) states that, “If this basic goal is kept fixed in view and acted on with imagination, creative and fruitful dialogue – and a growing transformation of each participant’s life and that of their communities – will follow” (p. 19). So for better results out of interfaith dialogue, the real meaning of dialogue should not be forgotten. Be sure to explain dialogue as “… a discussion in which the interlocutors search honestly and without bias for the best solution to a controversial problem” (Perelman and Olbrechts- Tyteca, 1969, 37).

2) In these meetings, participants must be aware of the fact that all of the participants are from different religious and cultural backgrounds, so interfaith dialogue is based on understanding and respecting all participants. In interfaith dialogue, none of the participants should try to discredit or question the belief system of the other participants.

3) Smock (2002) writes that stating the purpose of the meeting very clearly and choosing the right participants goes a long way towards determining the success of a dialogue. The purpose of the meeting should be decided by the participants before the meetings, very clearly and in detail.

4) While describing how to start dialogue, Bohme et al. (1991) state that suspension is an important part of dialogue. Listening to the other participants is a compulsory part of the process. During these meetings, all of the participants should be free of their biases and be open to understanding and recognizing new perspectives. Interfaith dialogue meetings are great ways to learn about different religions and different thoughts.

5) It should not be forgotten that in these meetings, we come together as people, not as belief systems, but these meetings provide an incredible opportunity to learn about, discuss, and understand other religions. “… the dialogue among the world’s religions and traditions should lead to a better mutual knowledge and understanding, and an exchange of the mutual values as an enrichment of one’s own faith and of the faith of the others” (Cosijns & Braybrooke, 2008, 55-56). However, a problem or mistake made in the meetings should not be used to generalize about a whole belief system. Kurucan (2006) states that by interfaith dialogue, “We refer to dialogue between the people of different religions” (17). So people in these meetings should not be seen as categories, sole representatives of their religions, but they should be seen as individual people, with their strengths and flaws – just like all of us.

6) Interfaith dialogue aims to find solutions to the problems of the world and other people by focusing on the similarities between belief systems. It does not focus on the differences and controversial issues.

7) Smock (2002) states that one-time interfaith dialogue meetings cannot be very useful, so there should be some follow-up sessions to enforce the benefits of the meetings.

8) In addition, it would be a good idea to learn about the religious practices of the other participants, see the differences between your own understandings, and be very careful about these differences during the dialogue process. Crowley (2006) states that setting the stasis – the parts that the participants may have different ideas about – is an important part of civil discussion. In interfaith dialogue, being aware of the stasis is important, so as not to offend the other participants.

9) No exclusives and no syncretism. Abu-Nimer et al. (2007) state that in interfaith dialogues, no religion should be excluded. This would be a huge handicap for the success of interfaith dialogue. Abu-Nimer et al. (2007) also highlights that trying to synchronize all religions into one can be just as dangerous as exclusiveness. As stated above, it is very crucial to accept all religions and religious people in their own belief system.

10) Dialogue can only happen between equals. If a religious group sees one group as inferior or even superior to another, no dialogue can happen. There cannot be sharing and understanding between the groups, which is the main aim of any interfaith dialogue.

Interfaith dialogue is an important concept in the globalized world. People from different religions live side by side in the globalized village and there are tons of problems that human beings face today. These interfaith groups are very crucial for a world in which “every day, almost 16,000 children die from hunger-related causes. That’s one child every five seconds” (www.bread.org). The role of the interfaith dialogue in solving these problems cannot be underestimated. Smock (2002) states that “while religion can and does contribute to violent conflicts, it can be a powerful factor struggling for peace and reconciliation (viii).

References

• Abu-Nimer, M. & Khoury, A. & Welty, E. 2007. Unity in diversity: Interfaith dialogue in the Middle East. Washington, DC: United States Institute of Peace.
• Bohm, D. & Factor, D. & Garrett, P. 1991. Dialogue: A Proposal. Retrieved from http://www.david-bohm.net/dialogue/dialogue_proposal.html
• Cosijns L.F. & Braybrooke , M. 2008. Dialogue among the faith communities. Lanham, MA: Hamilton Books.
• Crowley, S. 2006. Toward a civil discourse: Rhetoric and Fundamentalism. Pittsburg, PA: University of Pittsburg Press
• Gulen, M.F. 2000. “Necessity of interfaith dialog.” The Fountain Magazine. Issue 31.
• Kot, Z. 2009. “Muslim-Christian relations: The traditionalist interfaith dialogue” (Unpublished master thesis) George Washington University, Washington, DC.
• Kurucan, A. 2006. Nicin Diyalog: Diyalogun temelleri. Uskudar, Istanbul: Isik Yayinlari
• Perelman C.H. & Olbrechts- Tyteca, L. 1969. The new rhetoric: A treatise on argumentation. Notre Dame, IN: University of Notre Dame Press.
• Pinto, H. 2003. Faucault, Christianity and interfaith dialogue. New York, NY: Routledge Publications
• Smock, D. R. 2002. Interfaith Dialogue and Peacebuilding. Washington, DC: United States Institute of Peace.
• Swidler, L. & Duran, K. & Firestone, R. 2007. Trialogue: Jews, Christians and Muslims in Dialogue. New London, CT: Twenty-Third Publications.

In fact, such a journey is not specific to humanity: all creatures come into being in order to go through a difficult journey according to their level. And then they keep flowing into different molds and undergoing constant transformations until they reach their own identity; sometimes, they even transform into a second existence. They do this through pain, suffering, death, and resurrection, a few times in every moment.

Water cannot vaporize and attain purity without the challenge of the heat; a seed cannot sprout and rise to a higher life form without cracking and decomposing. Rivers cascade down and hit rocks to become as pure as the raindrops of a cloud. Spring does not come without winter. Even if it did, it would not be appreciated. Gold owes its value and brightness, and steel owes its hardness and durability, to the melting pots they were formed in. A bone dry land revives and serves as a bed for thousands of flowers in proportion to the amount of lightning flashing over it. Darkness cocoons light in its bosom, to its own disadvantage. Winter always weaves its canvas for the benefit of spring. Hence, a spring follows every winter, and a day follows every night. Deaths are for resurrection, and sufferings are for attaining a more beautiful life. By dying and resurrecting thousands of times throughout their lives, individuals are freed from the dark and deceiving pressures of the “ego” and reach eternity in their soul. A community ripens, matures, and attains immortality through the sufferings it undergoes and by clawing its way against the troubles it faces.

What a pleasure it is to die and resurrect time and again in order to attain eternal existence! How enjoyable it is to consider every blow a warning, telling us to come to our senses! What a great heroism it is to maintain hope and embrace the future in the face of so many misfortunes! Those who live their lives with faith and consciousness fly away through this journey of tribulations with wings of hope, under the bright light of their thoughts, through this land of trials and its seas of pus and blood. They are aware that they have come here to be distilled and purified. And they know that they can be skinned like the great Sufi Nesimi (d. 1417) or executed like Mansur (d. 922). Since they welcome both divine wrath and grace, and since they see the cure within the affliction, they watch what befalls them with pleasure and admiration, and they never panic. Every new misfortune becomes a plectrum, sounding out different tunes in their hearts and invigorating them with fresh excitements. For them, sufferings are no different than snowstorms on high mountaintops. They are nothing unusual. We can even say that living without suffering at all becomes an irresistible torment for them; it would mean their death. This is particularly true if their people are suffering and their values are being destroyed!

The most glorious servants of God did not spend a moment without suffering with such concerns. The same can be said for those who guided their nations to light: Imam Abu Hanifa (d. 767), one of the immortal guides of humanity with his fresh ideas and well-placed comments, was subjected to a raw deal and thrown into prison; he endured a life of suffering. Ahmad ibn Hanbal (d. 855) was mistreated like a worthless person and underwent the meanest tortures – and this lasted for years! Sarahsi (d. 1096) wrote his masterpiece Al-Mabsut in the bottom of the well in which he was imprisoned. And there were many more who suffered …

As those mature souls were subjected to tortures, as if they were being squeezed in presses, their blessed heads reached the realms beyond the heavens, and they became infinite sources of light with their enlightened hearts on the path to the revival of their people. People like Campanella (d. 1639), Cervantes (d. 1616), and Dostoyevsky (d. 1881) discovered themselves in captivity and reached immortality in the hearts of their people.

Everybody who bears the thought of serving humanity must know that the duty is sacred; the journey is long; the roads are steep; and different evils await them on this road. At every corner they will face death. They will be insulted, as if they were contemptible criminals, and most of the time they will be deprived of their right to live like human beings. They should be dedicated to this blessed cause with such awareness. Otherwise, some immature and heedless souls might change their course and direction due to petty hardships and deprivations.

O, you lazy soul! You expect it to rain without any thunder; you expect greenery without any seeds being cracked and no grains being sacrificed! You expect mothers to deliver babies, but without any labor pains! Namely, you expect the general course of divine destiny and order, in spite of its splendid wisdom, to be shaped according to your personal considerations. No! You have not come to this world for fun, for living according to your fancies and fantasies. You have come for the sake of realizing your inherent human potentials and cultivating the exalted qualities in your essence, for the sake of your inner enlightenment. So that you may become a mirror to reflect the divine, you will be put into melting pots many times over and burned in fire; you will be pushed through barrels of needles and undergo many trials!

These are the rules of the way, and the rest is futile and deceptive!

“Do not, then, be faint of heart, nor grieve,
For you are always the superior side if you are (true) believers.”

Here is the reviving breath to cure hearts!

The human cerebrum is divided into two hemispheres, the right and left. These sides are not identical to one another in structure or function. The right hemisphere is in charge of coordinating functions related to the left side of the body, and the left part of the brain controls the right side of the body. To date, science hasn’t been able to explain the reason for this split.

There are other differences between the hemispheres, including functions like speech and motor skills. For example, in 90% of people, speech and hand skills are centered in the left hemisphere. However, skills such as drawing, architecture, or sense of perspective – skills that are spatial and dimensional – are dominated by the right hemisphere. While the two hemispheres are employed for various tasks, they communicate with each other. For this to happen, a structure called the corpus callosum, which contains only axons as nerve extensions, is placed between the two hemispheres and enables the transfer of information. For instance, if a needle sticks your left hand, this is perceived by the right hemisphere. In patients where the corpus callosum is missing or disconnected, when an image of a red apple is shown with the left eye closed and again with the right eye shut, the patient will report having seen no apple.

The lack of a corpus callosum is rarely encountered as a birth defect (corpus callosum agenesis). In this instance, there is rarely a deficiency when it comes to movements and sensory receptions. Activities such as speaking, standing, balancing, walking and running are almost similar to normal levels.

In the case of epilepsy, an abnormal electric current is observed in the cerebrum. The corpus callosum can be cut by surgery, disconnecting the two hemispheres in order to prevent the dispersal and transfer of abnormal electricity to the other hemisphere of the brain.

These days, this surgery is not implemented unless necessary. Obviously, performing this surgery means communication between the two hemispheres is interrupted; the tasks that are assigned to the right brain remain only in the right and the ones assigned to the left brain stay in the left. This can complicate basic motor skills. For instance, if a person wants to write or throw a ball with two hands, this task is first planned in the left hemisphere, then it is transferred to the motor-skill regions found in both hemispheres via the corpus callosum. These skills are developed via both sides of the brain and our hands, and usually one hand is better in these skills than the other. Because the left brain is usually dominant, most people are right handed.

Schizophrenia is a permanent psychiatric disease that affects a person’s emotions, thoughts, and behaviors. It means being split-minded, or the separation of the mind (in Greek, schizo means split, or divided, and phrenos means mind). In schizophrenia, the coordination between the hemispheres is disrupted and the two hemispheres intervene simultaneously to solve the same problem. Briefly, it may not cause a problem if a specific task requires only one hemisphere to be in charge; however, complications arise when both hemispheres try to solve the same job. In schizophrenic patients, it has been reported that a problem exists in the corpus callosum; therefore, communications are hindered between them. This results in a disruption.

At this point, some questions may arise. Why is our body controlled by two brain regions that have different jobs? Why do these two hemispheres communicate? What would happen if our brain was not built in two parts?

It’s hard to give answers to these questions. Sometimes, we end up with nothing to say but, “if God creates in this way, then it must be in the most beautiful form.” There is nothing useless, extra and unnecessary in the human body. But the following can be hypothesized regarding the two sided functioning of the brain: cerebral hemorrhages always occur in only one side of the brain. Speech is lost if the left side is injured, and spatial and geometrical skills are lost when the right side is injured. Therefore, maybe while a function is lost on one side, the functions of the other side are conserved.

Though the different hemispheres of the brain are in charge of different functions, they successfully fulfill their duty to activate our bodily functions through constant communication. Despite continuing clinical studies, the full extent of the brain’s power remains mysterious. Its incredible design, which allows the body to function so perfectly, is a sign of humanity’s remarkable architecture.

MicroRNAs as tiny regulators with big roles

Tiny RNAs, known as microRNAs, have been shown to regulate many components of the body’s cellular machinery. They are called microRNAs because they are only 22 nucleotides in size (compared to the 2200 nucleotide-long messenger RNA). Amazingly, these small non-coding RNAs can turn off the translation of their target genes. They act as control switches by targeting the 3′ untranslated regions of messenger RNAs (mRNA) for translational repression or cleavage, thus resulting in a reduction of protein levels. Because each microRNAs can regulate hundreds of messenger RNAs, there are probably few cellular processes not affected by microRNAs. For instance, microRNAs have recently emerged as playing important roles in a variety of cellular processes, such as heart development, stem cells, insulin secretion, and cholesterol synthesis. MicroRNAs were first discovered in worms more than 20 years ago. For many years, scientists thought that DNA was transcribed to RNA, and then translated to protein. Those proteins are major regulators in the cell. Now, they appreciate that there are more levels of control and a number of non-coding RNAs that regulate the level of cellular components. About one thousand microRNA genes have been discovered in the human genome. This makes the microRNAs one of the most abundant classes of regulatory genes. As a result of the discovery of this new and major level of regulation in the cell, Dr. Andrew Z. Fire and Dr. Craig C. Mello were awarded the 2006 Nobel Prize in Physiology or Medicine.

MicroRNA biogenesis

Unlike other RNAs, the production of microRNAs is quite different. As depicted in figure 1, the generation and activity of microRNAs requires special microprocessors, known as RNA polymerase II, Drosha, Exportin, Dicer, and RISC complex. RNA polymerase II transcribes (reads the microRNA DNA code) primary microRNA transcripts; then the Drosha process transforms primary microRNA into precursor microRNA in the nucleus. For activity and further processing, precursor microRNA are exported into cytoplasm by Exportin. In the cytoplasm, Dicer cuts precursor microRNA and generates mature 22 nucleotide long microRNA. Then, mature microRNA are incorporated into the RNA inducible silencing complex (RISC) where they target messenger RNAs (mRNA), either for degradation or translational repression. Even though there are extensive studies on microRNAs, it is still mostly unknown how microRNAs target specificity is determined and how they target messenger RNAs for mRNA degradation or translational repression. For a functional microRNA in the cell, it is amazing that a series of microprocessors should take place. They recognize different microRNAs as substrates and do their job as they are supposed to. It seems that the existence and regulation of microRNA processing abilities cannot be by mere chance.

MicroRNAs as therapeutics

MicroRNAs are considered “fine tuners” of cellular processes because of their subtle effects on their targets. However, because microRNAs can target a number of genes and genetic pathways, the study of microRNAs and their regulation and role in diseases is highly promising in terms of developing new therapeutic approaches. Treatments by targeting microRNAs using microRNA inhibitors (antisense RNA nucleotides) are under intense study and several of them have been shown to be effective in animal models. A MicroRNA known as miR-122, for instance, has been shown to regulate cholesterol levels. Scientists targeted this liver-specific microRNA by using a microRNA inhibitor and they found that the downregulation of miR-122 resulted in a 40% decrease in cholesterol levels in the blood.

MicroRNAs in cancer therapy

With the discovery of new and better tools to detect and manipulate microRNA levels in cell cultures and tissues, researchers are now attempting to identify the specific features of each microRNA and their role in cancer and other devastating diseases. There are some microRNAs that are highly correlated with cancer formation. Cancer is cellular anarchy characterized by a proliferation of cells without control. A group of miRNAs known as the miR-17-92 family have been found to increase, and their higher levels result in cancer formation as found in some lymphomas and solid tumors. It is believed that better understanding and use of microRNAs or microRNA inhibitors could enable doctors to treat diseases like cancer. In the near future, microRNA studies are also expected to provide early detection of progressive diseases, better markers for cancer initiation, and cancer specific drug selections.

MicroRNAs as cancer drug boosters

The most straightforward application of microRNA research has been cancer chemotherapies. The potential of use of microRNA applications to increase the effectiveness of current cancer drugs seems highly likely. Companies and universities are looking for microRNA partners to increase the effects of drugs like Taxol, which is currently used in chemotherapy. Taxol, for example, currently works for about 30% of lung cancer patients. But, if we can find a microRNA partner with that drug to make it 40%, it will mean saving thousands of lives. This is a hopeful sign for the future of cancer treatment. On the other hand, it is known that in the case of any chemotherapy, there are unwanted side effects. Although use of higher dose of drug will kill more tumors, the side effects of this drug will cause other issues. Discovery of partners like microRNAs that boost the effectiveness of cancer drugs or decrease side effects can help to treat more patients or help them overcome unwanted side effects.

Taking microRNAs to the heart of the matter

Heart diseases represent the primary cause of death in developed countries. Recent studies have identified microRNAs associated with heart diseases, including cardiac hypertrophy, heart failure (inability of the heart to pump sufficient blood to the organism), and myocardial infarction (the death of the cardiac muscle resulting from interruption of the blood supply). Mir-1 expression levels, for example, are low in human heart disease and it is known to regulate Hand2, a protein required for the growth of heart muscle cells. The levels of another microRNA, called miR-21, have consistently increased through cardiac stress and have been shown to regulate cardiac growth as well. Importantly, miR-133 is believed to repress cardiac hypertrophy, thus the use of synthetic miR-133 molecules is possible as a therapeutic for patients with pathological hypertrophy. However, more studies to understand heart-associated miRNAs are needed in order to have clinical trials for the treatment of heart diseases.

Figure 2. MicroRNAs in the heart. Recent studies have identified microRNAs that are associated with heart diseases, including arrhythmic heartbeat (Arrhythmias), cardiac hypertrophy (enlarged heart), septation defect, and cardiac muscle overgrowth (myocyte hyperplasia).

Micromanaging insulin secretion

MicroRNAs are also associated with the onset of diabetes. Diabetes affects about 23.6 million people in the United States. It can lead to serious health issues and even early death. Diabetes is marked by high levels of blood glucose (also called blood sugar). Complications of the disease are due to defects in insulin production and insulin action. Insulin is among the major regulators of sugar levels in the blood. The human genome contains a number of microRNA genes, whose functions are only beginning to come to light. One such microRNA, miR-375, is already implicated in the secretion of insulin from pancreatic cells, thus it represents a novel pharmacological target for the treatment of diabetes.

The mentioned cases above are examples of the tiny RNAs which regulate cellular processes. The loss of the control in such a small component of the cellular machinery can lead to serious problems, like cancer. To use a metaphor, the regular and healthy government of a state does not allow for the presence of multiple governors. Similarly, regulatory tiny RNAs require a controller who knows how the human body works at the macro and micro levels. This forces us to consider that whomever is controlling the human body must be all sustaining and all knowing. With each new scientific breakthrough, the wisdom of creation becomes more and more apparent. The field of miRNAs is a young research area. New discoveries about microRNAs have brought us new hopes for novel therapies to human diseases. However, future discoveries are required before these therapies can be used in a clinical setting.

Resources

• Qur’an: The Family of Imran 191 and The Cow 255.
• Caldas & Brenton. “Sizing up microRNAs as cancer genes”. Nature, 2005.
• Scott M. Hammond. “MicroRNA therapeutics: a new niche for antisense nucleic acids” Trends in Molecular Medicine, 2006.
• Rooij et al. “Toward MicroRNA–Based Therapeutics for Heart Disease” Circulation Research, 2008.
• National Diabetes Statistics, 2007. Retrived from http://diabetes.niddk.nih.gov/DM/PUBS/statistics/
• ScienceDaily. Not ‘Junk DNA’ After All: Tiny RNAs Play Big Role Controlling Genes. 2007.
• Callis & Wang. Taking microRNAs to heart. Trends in Molecular Medicine. 2008.
• Poy et al. A pancreatic islet-specific microRNA regulates insulin secretion. Nature,2004.
• Average mRNA length: B. Lewin, Genes 5, Table 2-2. Oxford University Press.
• MicroRNA biogenesis figure: http://content.nejm.org/content/vol359/issue25/images/large/14f1.jpeg

When will I learn to embrace every moment,
to surrender everything to God?

I hear you waiting for an answer.
Perhaps when waiting
has also been surrendered
and there is only one
person writing and reading these words,
my Love will be complete.