{module Science Square (Issue 128)}

First miniature human heart printed

Noor N et al. 3D Printing of Personalized Thick and Perfusable Cardiac Patches and Hearts.  Advanced Science, April 2019.

In a major breakthrough, researchers have “printed” the world’s first 3D vascularized engineered heart using a patient’s own cells and biological materials. This could have huge repercussions for human health: the World Health Organization said that last year, ischemic heart disease and stroke were the world’s leading cause of death for both men and women. Heart transplantation is currently the only treatment available to patients with end-stage heart failure. Given the serious shortage of heart donors, scientists have been trying to develop new “3D organ printing” approaches to regenerate the diseased heart. Past studies were only able to print simple tissues without blood vessels. The new study showed for the first time that an entire heart with cells, blood vessels, ventricles, and chambers could be successfully engineered and printed. The researchers first took a biopsy of fatty tissue from patients and separated the cellular and a-cellular materials of the tissue. While the cells were reprogrammed to become pluripotent stem cells, the extracellular matrix – a 3D network of extracellular macromolecules such as collagen and glycoproteins – were processed into a personalized hydrogel that served as the printing “ink.” After being mixed with the hydrogel, the cells were then robustly differentiated to cardiac or endothelial cells to create patient-specific, immune-compatible cardiac patches with blood vessels and, subsequently, an entire heart. The heart was 3D-printed in about three hours and was too small for humans. It was the size of a rabbit’s heart (~ 2.5 centimeters). But it is completely biocompatible and, most importantly, matches the patient, which reduces the chances of organ rejection inside the body. A human-sized heart might take a whole day to print and would require billions of cells, compared to the millions used to print these mini-hearts. While it’s not clear if a printer can produce hearts that are equal or superior to human ones, perhaps by printing patches there will be a possibility to improve or take out diseased areas in the heart and replace them with something that works. Researchers hope that maybe in 10 years, there will be organ printers in the finest hospitals around the world, and these procedures will be conducted routinely.

Bacterial factories for spider silk

Zhang F et al. Synthetic Biology for Microbial Production of Protein-based Materials, the American Chemical Society (ACS) National Meeting & Exposition, Spring 2019.

Spider silk has always fascinated researchers due to its lightweight and superior strength and numerous applications in areas such as drug delivery, smart textiles, and artificial muscles. It is one of the strongest natural materials in the world. It is thinner than a human hair, but its strength is more than that of steel, pound for pound. Since farming spiders is incredibly inefficient, scientists have been trying for decades to find a way to mass produce the material from genetically modified bacteria, yeast, and even goat milk, but these efforts have always fallen short. The biggest challenge was that the genetic information for dragline silk is a long string of repeating DNA, and, in previously tested organisms, cellular machinery arbitrarily alters or chops up such DNA sequences. To circumvent this problem, researchers precisely separated the repeating DNA into bits and inserted each repeating piece separately into bacterial genome. These smaller DNA pieces produced small peptides that ended up combining in bacteria and formed a strand of silk. The researchers also added to the end of each strand a chemical tag that glued the individual fibers together. This method was able to produce 2 grams of spider silk for each liter of bacteria and the resulting material behaved exactly like dragline silk. Its tensile strength was measured at 1.03 gigapascals, about the same as for naturally produced dragline silk. The engineered silk’s toughness measured 114 megajoules per cubic meter, compared with around 100 megajoules for silk made by spiders. And the engineered silk strands could stretch 18 percent before breaking, the same as natural dragline silk. The new silk was developed in part with NASA funding for applications such as giving astronauts a means of producing tough materials while on Mars. But the substance could be used in designing stronger materials for robotic, medical, or textile applications.

Electricity from falling snow

Ahmet A et al. All printable snow-based triboelectric nanogenerator. Nano Energy, April 2019.

Researchers have designed a new device with which we can now obtain electricity from falling snow. This new energy conversion method could become a new source of electricity in the future, especially in remote areas, as it does not need batteries. Researchers called it a Snow-based TriboElectric NanoGenerator, or Snow TENG. It is inexpensive, small, thin, and flexible like a sheet of plastic. After starting a charge from static electricity, energy is generated from the exchange of electrons. Snow is already positively charged by giving up its electrons, while silicone, a rubber-like material which consists of silicon atoms and oxygen atoms, is combined with carbon, hydrogen, and other elements to be negatively charged. When the positive-charged snow falls onto the surface of the silicone, the charges interact, and the Snow TENG captures the charge, which allows it to turn snowfall into electricity. 30% of Earth’s surface is covered by snow each winter, which is also the time when solar panels, one of the most reliable renewable sources of energy, aren’t very effective. Snow accumulation reduces the amount of sunlight that reaches the solar array, which makes them unable to operate. Snow TENG could be integrated into solar panels and provide a continuous power supply, even at a time when it’s snowing. Researchers used 3D printing to design the small device. It consists of a layer of silicone and an electrode which can capture the electric charge. Given that silicone is widely used in the industry, this method could dramatically reduce the global costs of producing electricity.

The human cerebrum is divided into two hemispheres, the right and left. These sides are not identical to one another in structure or function. The right hemisphere is in charge of coordinating functions related to the left side of the body, and the left part of the brain controls the right side of the body. To date, science hasn’t been able to explain the reason for this split.

There are other differences between the hemispheres, including functions like speech and motor skills. For example, in 90% of people, speech and hand skills are centered in the left hemisphere. However, skills such as drawing, architecture, or sense of perspective – skills that are spatial and dimensional – are dominated by the right hemisphere. While the two hemispheres are employed for various tasks, they communicate with each other. For this to happen, a structure called the corpus callosum, which contains only axons as nerve extensions, is placed between the two hemispheres and enables the transfer of information. For instance, if a needle sticks your left hand, this is perceived by the right hemisphere. In patients where the corpus callosum is missing or disconnected, when an image of a red apple is shown with the left eye closed and again with the right eye shut, the patient will report having seen no apple.

The lack of a corpus callosum is rarely encountered as a birth defect (corpus callosum agenesis). In this instance, there is rarely a deficiency when it comes to movements and sensory receptions. Activities such as speaking, standing, balancing, walking and running are almost similar to normal levels.

In the case of epilepsy, an abnormal electric current is observed in the cerebrum. The corpus callosum can be cut by surgery, disconnecting the two hemispheres in order to prevent the dispersal and transfer of abnormal electricity to the other hemisphere of the brain.

These days, this surgery is not implemented unless necessary. Obviously, performing this surgery means communication between the two hemispheres is interrupted; the tasks that are assigned to the right brain remain only in the right and the ones assigned to the left brain stay in the left. This can complicate basic motor skills. For instance, if a person wants to write or throw a ball with two hands, this task is first planned in the left hemisphere, then it is transferred to the motor-skill regions found in both hemispheres via the corpus callosum. These skills are developed via both sides of the brain and our hands, and usually one hand is better in these skills than the other. Because the left brain is usually dominant, most people are right handed.

Schizophrenia is a permanent psychiatric disease that affects a person’s emotions, thoughts, and behaviors. It means being split-minded, or the separation of the mind (in Greek, schizo means split, or divided, and phrenos means mind). In schizophrenia, the coordination between the hemispheres is disrupted and the two hemispheres intervene simultaneously to solve the same problem. Briefly, it may not cause a problem if a specific task requires only one hemisphere to be in charge; however, complications arise when both hemispheres try to solve the same job. In schizophrenic patients, it has been reported that a problem exists in the corpus callosum; therefore, communications are hindered between them. This results in a disruption.

At this point, some questions may arise. Why is our body controlled by two brain regions that have different jobs? Why do these two hemispheres communicate? What would happen if our brain was not built in two parts?

It’s hard to give answers to these questions. Sometimes, we end up with nothing to say but, “if God creates in this way, then it must be in the most beautiful form.” There is nothing useless, extra and unnecessary in the human body. But the following can be hypothesized regarding the two sided functioning of the brain: cerebral hemorrhages always occur in only one side of the brain. Speech is lost if the left side is injured, and spatial and geometrical skills are lost when the right side is injured. Therefore, maybe while a function is lost on one side, the functions of the other side are conserved.

Though the different hemispheres of the brain are in charge of different functions, they successfully fulfill their duty to activate our bodily functions through constant communication. Despite continuing clinical studies, the full extent of the brain’s power remains mysterious. Its incredible design, which allows the body to function so perfectly, is a sign of humanity’s remarkable architecture.

“The most beautiful system [the universe] could only proceed from the dominion of an intelligent and powerful Being.” (Isaac Newton)

The Newtonian physics, quantum mechanics, and the theory of relativity took the modern community to the boundary of the two realms of physical and metaphysical existence. Nevertheless, the nature of the fundamental physical dimensions still remains an open question resting on the related areas of science

The fundamental concepts of Newtonian physics are Time, Length, Mass, and Electric Charge by means of which all the other classical physical quantities such as velocity, force, momentum, energy, current, electric field, magnetic flux, etc. can be derived and expressed as their combinations. Classical physics stands on the assumption that material, having two basic intrinsic properties of mass and charge, and immaterial phenomena are all contained in an absolute space and an ever-flowing absolute time. These four physical dimensions, without asking the nature of them, provide a practical framework for a description of the gravitational and electromagnetic forces and thus a description of the physical world and an interpretation of the events occurring in it up to a certain degree. However, the Newtonian picture of the universe is neither adequate for a deeper understanding of the corporeal reality nor appropriate for linking that reality to the ones possessing higher degrees of the Universal Existence.

Starting from late 19th and early 20th centuries, the Newtonian picture of the world has been changed due to two revolutionary theories, which have been proved both experimentally and theoretically that they are superior to and not compatible with the classical descriptions and assumptions. They are the relativity theory and the quantum mechanics. In physics, a field is a physical quantity associated with each point of Space-Time. For example, the Newtonian gravitational field is a vector field specifying its value at a point in Space-Time, which requires three numbers, the components of the gravitational field vector at that point. Quantum field theory constructing quantum mechanical models of systems classically parameterized by an indefinitely big number of degrees of freedom, namely fields, is the natural and quantitative language of particle physics. The current set of fundamental fields and their dynamics are summarized in a theory called the Standard Model. All particles and their interactions observed to date can be described almost entirely by the Standard Model although most particle physicists believe that it is an incomplete description of nature, and that a more fundamental theory, the Theory of Everything, awaits discovery. Figure 1 represents an overview of the various families of elementary and composite particles, and the theories describing their interactions.

The relativistic quantum field theory of the subatomic world does not only include the strong and weak nuclear forces in addition to the electromagnetic and gravitational interactions of the classical picture, but also provokes some ideas about the nature of the fundamental concepts of the classical physics. Symmetry of a physical system is a physical or mathematical feature of the system that is preserved under some change. The Standard Model says, for instance, that the electric charge is the generator of the U(1) symmetry of electromagnetism. U(1), the unitary group of rank 1, is the simplest internal symmetry group of the Standard Model. It can be visualized as the rotational symmetry of a circle about a perpendicular axis passing through the center of the circle. It represents a continuous symmetry because a circle can be rotated by an angle and remains unchanged. It is an internal symmetry since this circle does not lie in the physical space but in the complex plane of mathematics. More abstractly and more generally, a charge is any generator of a continuous symmetry of the physical system under study. When a physical system has a symmetry of some sort, Noether’s theorem implies the existence of a conserved current. The thing that flows in the current is the charge; the charge is the generator of the symmetry group. This converts our classical concrete idea of electric charge into a mathematical abstraction. Conservation of energy and conservations of linear and angular momenta are nothing but the applications of Noether’s theorem to the translational symmetry in time and translational and rotational symmetries in space, respectively.

Classically, which is equivalent to macroscopically, mass is associated with matter and can be defined as a quantitative measure of an object’s resistance to the change of its speed. But in the Standard Model of the subatomic scale, the mass of the elementary particles are explained by the Higgs mechanism which refers specifically to the generation of masses for the W and Z bosons through electroweak symmetry breaking. The Large Hadron Collider at CERN is currently searching for Higgs bosons, and attempting to understand the electroweak Higgs mechanism. The Higgs mechanism is the process that gives mass to elementary particles. In 1905, Einstein proposed mass-energy equivalence (E=mc2) in his paper entitled “Does the inertia of a body depend upon its energy-content?” In relativity, all of the energy that moves with an object (that is, all the energy which is present in the object’s rest frame) contributes to the total mass of the body, which measures how much it resists acceleration.

When we come to the remaining two fundamental concepts of Newtonian physics, we see that Time and Length, which we know instinctively, are no exceptions. The modern physics challenges our classical understandings of them too. Relativity theory argues that Time and Space are of equal ontological status; the reality is the 4-dimensional unity of Space-Time. Physics could no longer be understood as Space by itself, and Time by itself. It also states that simultaneity is relative, so there is no objective way to define a “Now” that would be the same for all states of motion which substantially affects the idea of causality. In addition, this Space-Time is not flat but rather curved due to the material and energy contained in it and not static but dynamic. Time and Space are neither uniform nor absolute.

The missing part of the so-called Theory of Everything is the quantum gravity, which attempts to develop scientific models that unify quantum mechanics describing three of the four known fundamental interactions with general relativity describing the fourth, gravity. The following quotation is from one of the leading quantum gravity researcher, Carlo Rovelli, stated in 1997:

“I believe that we are going through a period of profound confusion, in which we lack a general coherent picture of the physical world capable of embracing what or at least most of what, we have learned about it. The fundamental scientific view of the world of the present time is characterized by an astonishing amount of perplexity, and disagreement, about what time, space, matter, and causality are. But if a new synthesis is to be reached, I believe that philosophical thinking will be once more one of its ingredients. Due to the vastness of the problem involved, the generality and accuracy of philosophical thinking and its capacity to clarify conceptual premises are probably necessary to help physics out of a situation in which we have learned so much about the world, but no longer know what matter, time, space, and causality are.“

Lee Smolin, another theoretical physicist named as #21 on Foreign Policy Magazine’s 2008 list of Top 100 Public Intellectuals, stated the following in 2001:

“Atoms do fall, so the relationship between gravity and the quantum is not a problem for nature. If it is a problem for us, it must be because somewhere in our thinking there is at least one, and possibly several, wrong assumptions. At the very least, these assumptions involve our concept of space and time and the connection between the observer and the observed.”

It is true that quantum mechanics and the theory of relativity were born and are growing in the nontraditional atmosphere of the scientific enterprise. Thus, they can be considered as sharing the reductionist character of the Newtonian physics by having no direct reference to the hierarchy of physical and metaphysical existence. Nevertheless, we consider them as an improvement since they took the modern scientific community to the boundary of the two realms, by asking the old question of ancients about the nature of the fundamental physical dimensions. The mystery of them is still an open question resting, we believe, on the related areas of science and metaphysics.

Yusuf Ali, in his translation of the Qur’an, asks several questions about lightning: Why look to evil rather than to good? To punishment rather than to mercy?”To the fear in the force and fire of the lightning rather than to hope of good and abundant crops in the rain which will come behind the lightning clouds (note 1818); Nay, thunder itself which may frighten you, is but a tame and beneficent force before Him, declaring His praises, like the rest of creation. Thunder thus aptly give the name to this surah of contrasts, where what we may think is terrible is shown to be really a submissive instrument of good in God’s hands (note 1819); and: To cowards, lightning and thunder appear as terrible forces of nature. Lightning seems to kill and destroy where its irresistible progress is not assisted by proper lightning”conductors. But lightning is also a herald of rain-bearing clouds and showers that bring fertility and prosperity in their train (3530).

Journals publish articles on injuries and death caused by lightning. However, the Qur’an specifically mentions the hope of lightning as a good or beneficent force. This article addresses this issue.

What are ions?

After a storm, the air feels clean and fresh filled with negative ions. People often report feelings of pleasantness and well-being following an electrical storm. Electrical storms are generally preceded by higher levels of positive ions and followed by higher levels of negative ions.

Air is made of individual molecules. When the outer electrons of two or more atoms join together, the resulting particle is a molecule. Each molecule, in turn, contains smaller particles of positive and negative charges (protons and electrons). Under normal circumstances, the number of protons and electrons are equal, and so their charges cancel out and leave the molecule electrically neutral. However, negatively charged electrons are lighter and more mobile. If they happen to absorb energy from intense sunlight, they tend to jump from one molecule to another. When a negative charge jumps from a molecule, it upsets the equilibrium and leaves behind more positive than negative charges. Thus the molecule becomes a positive ion. The electron arriving at the new molecule brings with it an extra negative charge. This molecule now becomes a negative ion. When the energy supply is removed, the electrons return toward the vacated spaces, and everything becomes balanced and has a zero charge.

Oxygen, a prime example of small gaseous molecules, remains neutral as long as the proton“electron balance is maintained. Since atoms have equal numbers of protons and electrons, they have no charge. However, if an electron is lost or gained, the molecule becomes positively or negatively charged, respectively, and an ion is created.

The simplest way to visualize an air ion is to consider it a tiny charge of static electricity carried by the air. This charge can be either positive or negative. The charged particles, or ions, are not merely suspended in the atmosphere; rather, they are part of the air’s very fabric. The air we breathe contains billions of tiny, invisible, electrically charged energy packets called ions, each of which have either positive or negative charges. Every time we take a breath, ions fill up our lungs and are carried by our blood into every cell in our body. Without ions in the air, our body could not process oxygen properly.

A lack or imbalance of ions affects the environment in which we live and breathe. Research shows that most of us who live, work, and travel in closed spaces suffer some degree of negative ion starvation or positive ion overabundance. This has become extremely evident to NASA in its space travel program.

People are spending their lives submerged in an atmospheric ocean of nitrogen, oxygen, and a small percentage of other elements, plus the toxins and pollution of our industrial world. In cities like New York, Los Angeles, Hong Kong, Tokyo, Mexico City, Karachi, Delhi, Bangalore, Mumbai, Calcutta, and many other densely populated cities, there may be few or no detectable negative ions at all during heavy traffic and high pollution periods.

In nature, abundant ions are generated wherever energy is transferred into the air by the friction within wind, rain, and surf. Certain events occurring in nature, such as lightning discharges, falling water, and air friction can cause electrons to be torn loose from a molecule. These orphan electrons are then adopted by other nearby molecules, which transforms them into negative ions. The parent particles become positive ions.

Negative ions carry the air’s electrical energy. Some examples of nature’s ion generators are solar (ultraviolet) and cosmic radiation, air friction, lightning, falling water (the splitting of water into droplets by waterfalls), ocean surf and waves, evergreens and Earth’s radioactivity (from natural radiation in rocks and soil).

The ion effect: Serotonin hypothesis

An excess of positive ions and a lack of negative ions can produce uncomfortable effects. Scientists have demonstrated that small air ions are biologically active. Moreover, they can stimulate the over-production of serotonin, a powerful neurotransmitter and very active neurohormone that causes profound nerve, glandular, and digestive effects throughout the body. Tests show that positive ions increase the production of serotonin and that negative ions decrease the hormone level.

High serotonin concentrations are associated with migraines. Negative ions accelerate the oxidative degradation of serotonin, whereas positive ions deactivate the enzymes that break it down. Thus more negative ions should reduce migraines. A higher serotonin level also produces tachycardia, higher blood pressure, bronchial spasms and even asthma attacks, increased intestinal peristalsis (intestinal contractions and dilations to push the contents through), increased sensitivity to pain, and increased aggression. Reduced serotonin levels result in a mentally relaxed state and reduce feelings of depression. Negative ions appear to reduce serotonin by enhancing monoamine oxidizing activity. Paradoxically, mental illness is often treated successfully with drugs that inhibit this activity and raise serotonin levels in the brain.

The three major effects of positive ion excess are irritation and tension, exhaustion, and a hyperthyroid response. The common symptoms of dizziness, headaches, depression, anxiety, and a generally lower level of physical and mental functioning were shown to be alleviated and, in most cases, reversed by increasing the negative ions in the air.

Positive ions

Many people find a pre-storm atmosphere heavy and oppressive. This has been attributed to the high levels of positive ions building up in the air, which are also believed to trigger storm-sensitivity in asthmatics and many other people. In the hours before a certain storm arrived, hundreds of people reported to hospital with severe asthma attacks. Was this due to positive ions?

Scientists have found that if the air is charged with too few negative and too many positive ions, we become anxious,tired, and tense. This positive-ion poisoning results from weather disturbances, central air conditioning, smog, and driving too long. It even has been linked to heart attacks, aggravated asthma, migraines, insomnia, rheumatism, arthritis, hay fever, and most allergies. However, a negative electrical charge imparts positive feelings of health and vitality.

Negative ions

Refreshing places, usually located in the mountains and near waterfalls and seashores, where health resorts are traditionally situated, have high negative ion concentrations. Areas with high levels of positive ions often make us feel uncomfortable and irritable.

In addition to providing a rewarding visual experience, waterfalls may be beneficial to our health. Those wishing to enhance their body and mind through breathing exercises should do so by a waterfall. Nearly everyone agrees that visiting a waterfall is a stimulating, refreshing, and energizing experience.

The energy produced by falling water causes negative ions, for as the falling water breaks into droplets, electrons (negatively charged parts of an atom) are separated from water atoms. These electrons combine with oxygen atoms in the air to create negative ions, which then are inhaled and absorbed into the bloodstream. Negative ions are not known to permanently cure anything. However, experts believe that they help our bodies by accelerating the delivery of oxygen to our cells. Some researchers believe that they may stimulate cells that regulate the body’s resistance to disease.

Plants grown in an ion-enhanced atmosphere show a marked increase in size and growth rate. Air-borne bacteria greatly diminish in number when there is a high negative ion count in the air. Synthetic materials, forced air circulation, improper humidity levels, excess static electricity, and a lack of fresh air all contribute to an ion imbalance. Natural negative ion levels should be maintained through full-spectrum lighting; natural materials on walls, floors, and furniture; windows that open to the outside; and living plants. These should be kept in mind when designing a place in which to live.

On average, 1,500 ions are found in a cubic centimeter (roughly the size of a sugar cube) of fresh air. Of these, about 45% are negative ions and the rest are positive ions. At Yosemite Falls in California, a reading of 100,000 negative air ions per cubic centimeter was recorded.

The fresh air after a thunderstorm, on a mountain top, or by the seaside are due to high negative ion concentrations. The reduced well-being often felt in highly polluted areas, cars, smog-enclosed areas, artificially air conditioned offices, or in hot dry weather conditions are usually due to an unduly low negative ion balance. Negative ions can be found in the billions on mountain tops, waterfalls, and by the sea. Radioactive substances in Earth’s crust and cosmic rays cause most ionization. But fire, crashing water, and plants during photosynthesis also produce negative ions. They give the air its invigorating freshness, which is so good for us.

Physiologically, the presence of negative ions in a sweat bath is as important as the heat. The discovery of negative ions in certain types of saunas a few years ago became headline news in Finland. Until then, the sauna’s healing power was attributed to relaxation and increased circulation. Now, negative ions add startling new possibilities.

Ions and our modern lifestyle

We now live in an environment that virtually eliminates negative ions. Rural areas have a higher concentration of ions, but many of us live in towns and cities that have very low levels due to dirt and pollution. Pollution from car exhaust, smoking, overcrowding, and even breathing all contribute to this.

Modern vehicles have many problems. For example, opening a window lets in polluted city air. Many drivers, especially long-distance ones, keep an ionizer in their vehicle to help them maintain a high level of alertness and concentration. In addition, this can relieve car sickness and remove pollen and smoke. In cities, closed rooms, cars and elsewhere, the proportion of negative ions is markedly reduced compared to what it is in undisturbed nature. According to experts, positive ions rob us of our good senses and dispositions, while negative ions enhance them, stimulating everything from plant growth to overall bodily well-being. In general, people who are sensitive to air-borne allergens will benefit far more and quicker from the cleansing action of negative ions.

A second potentially important factor is the person’s body voltage, for a high body voltage could alter considerably the ion ingestion rate. Perhaps the same effect as positive ion enhancement could be produced by a high negative body potential, even if the ambient air ion concentrations are balanced. Control and reduction of bodily voltage to a near-zero condition should reduce any such effects and restore ion ingestion due to the ambient air ion balance condition. For Muslims, body voltage to a near-zero condition is achieved when they prostrate during prayer.

Ironically, even today’s air-conditioned buildings, vehicles, and airplanes frequently become supercharged with harmful positive ions because the plastic and metal fans, filters, and air-conditioning duct systems strip the air of negative ions even before it reaches its destination. In addition, fluorescent lighting, electrical and electronic equipment, television screens, and static-producing as well as artificial fibers in carpets, clothes, and upholstery, all reduce the level of negative ions and increase the level of positive ions.

Desktop PCs have a cathode ray tube monitor that produces a positive static charge during normal operation. It also sweeps the nearby air of negative charges, depleting the negative-ion concentration in the immediate vicinity. Apparently when ion concentration is lowered by this or any other means, such as air conditioning, workers complain of headaches, lethargy, dizziness, and nausea. Tests conducted in England indicate that the more complex the task a person tries, the more he or she is affected by negative ion levels. Also, women are more responsive than men to negative ion depletion or enrichment.

The graph below provides some average sample readings of negative air ions taken in various locations. Note that the body responds to levels above 1,000 ions per cc.

Effects on our health

Besides cleaning the air, negative ions aid in mood elevation and increased oxygen intake, both of which make us feel more alert and energetic. Negative ions can provide major benefits for suffers of asthma, chronic fatigue syndrome, nervous energy, hay fever, allergies, sleep disorders and snoring, depression, emphysema, sinus, migraines, colds and flu, nausea, chemical sensitivity, fibromyalgia, cigarette smoke and other odors, and computers and office pollution.

Scientific studies

Research shows that negative ions can reduce histamine, which triggers hay fever; affect levels of serotonin, a neurotransmitter or a neurohormone associated with anxiety, stress, and migraines; help suffers of bronchitis, asthma, catarrh, the common cold, insomnia, migraines, emphysema, eczema, headaches, tiredness, and general feelings of malaise; speed the healing time of burns and surgical incisions with less cross-infection and reduced pain (including post-operative pain); enhance the body’s absorption and utilization of oxygen, thus assisting concentration and alertness; reduce the effects of passive smoking and allergies to pollen, dust, and pets; remove and destroy air-borne bacteria and viruses; and lower serotonin levels, which leads to greater calmness and strengthens defenses against infection, as proven with the flu.

Negative ions also increase hemoglobin/oxygen affinity so that the partial oxygen pressure in the blood rises while the partial dioxide pressure decreases. This results in a lowered respiratory rate and enhances the metabolism of water-soluble vitamins. In addition, negative ions increase one’s pH level, which makes bodily fluids more alkaline.

The effect of negative ion depletion varies from person to person. Negative ions in the bloodstream accelerate the delivery of oxygen to our cells and tissues, whereas positive ions slow this down and produce symptoms markedly like those in anoxia (oxygen starvation). Negative ions may stimulate the reticulo-endothelial system, a group of defense cells that marshal our resistance to disease. Treatment with negative ions has produced dramatic improvement in healing severe burns and reducing pain. Children, in particular, seem to respond quickly, for tests have shown that children breathing negatively ionized air were superior in incidental memory and had many difficulties in dichotic listening offset.

Offices and organizations having negative air ionization equipment have found that their employees are less likely to get colds or be absent, and generally are more cheerful and alert. Negative air ionizers are used in the closed and artificial atmospheres of submarines and spacecraft.

Conclusions

The Qur’an’s verses inspire people to make new scientific discoveries, as seen in 13:12, quoted above. Nature contains many sources of the negative ions that are so beneficial to people.

Reading and acquiring a deeper understanding of the Qur’an lead to many life-enhancing discoveries. Given the right conditions, healthy food and pure water, our bodies will usually right themselves and develop properly. But so often we neglect the air we breathe. Most of us live in environments full of invisible pollution and devoid of negative ions.

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