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	<title>enzymes &#8211; Fountain Magazine</title>
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	<link>https://fountainmagazine.com</link>
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		<title>Enriched by Exceptions: D-Amino acids</title>
		<link>https://fountainmagazine.com/all-issues/2014/issue-101-september-october-2014/enriched-by-exceptions-september-2014/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Mon, 01 Sep 2014 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 101 (September - October 2014)]]></category>
		<category><![CDATA[acid]]></category>
		<category><![CDATA[alanine]]></category>
		<category><![CDATA[amino acids]]></category>
		<category><![CDATA[aspartate]]></category>
		<category><![CDATA[bacteria]]></category>
		<category><![CDATA[D-amino acids]]></category>
		<category><![CDATA[discovered]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[feature]]></category>
		<category><![CDATA[form]]></category>
		<category><![CDATA[forms]]></category>
		<category><![CDATA[Gunther Kreil]]></category>
		<category><![CDATA[molecules]]></category>
		<category><![CDATA[peptide]]></category>
		<category><![CDATA[peptides]]></category>
		<category><![CDATA[poison]]></category>
		<category><![CDATA[produced]]></category>
		<category><![CDATA[protein]]></category>
		<category><![CDATA[racemase]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[serine]]></category>
		<category><![CDATA[synthesis]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2014/issue-101-september-october-2014/enriched-by-exceptions-september-2014/</guid>

					<description><![CDATA[When we browse through molecules &#8211; the building blocks of the universe &#8211; and their utilization in organisms, we observe a preference or a trend towards a direction (right or left). Functional groups of molecules have right or left placements based on an axis just like preferences of humans regarding left or right hand use. [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>When we browse through molecules &#8211; the building blocks of the universe &#8211; and their utilization in organisms, we observe a preference or a trend towards a direction (right or left). Functional groups of molecules have right or left placements based on an axis just like preferences of humans regarding left or right hand use. These molecules feature the same chemical structure or molecular formula but have different placements (mirror projections) that also display different functions. These differences generated during the synthesis of bio-molecules in living systems are called &#8220;chirality.&#8221; This type of difference is not observed in objects like a globe or equilateral triangle, which have the same mirror image as copies of their original forms. This feature of molecules is defined as L (left) and D (right) enantiomeric form. Five carbon ribose or deoxyribose (sugar) carrying D-enantiomeric forms are found in the structure of nucleic acids that encode the genetic information in living things.</p>
<p><span id="more-1683"></span></p>
<p>Despite that, there are more than 100 types of amino acids found in nature; only 20 of them are employed for protein synthesis. Among these 20 amino acids, excepting glycine, which does not display chirality, only the L-form of the 19 is used for protein synthesis. This is because ribosomes, where protein synthesis occurs, do not feature the utilization of D-form amino acids. As nothing in the universe exists in vain but with multiple tasks, D-amino acids have a job in the maintenance of life after protein synthesis in very different fashions. The way D-amino acids are employed in the execution and control of physiological preferences amazes scientists.</p>
<p>Up until recent times, D-amino acids were believed to be synthesized mostly by bacteria and plants, unlike mammals, and were considered dysfunctional as they passed, via consumption of nutrients, from bacteria and plants. However when D-amino acids were noticed for having roles as important as L-amino acids during the 1990s, the field gained significance. It was demonstrated that D-amino acids were found widely in invertebrates, vertebrates, and humans as free forms or inside proteins, undertaking critical functions in the nervous and endocrine systems. The most interesting point is the conversion of amino acids from the L-form into the D-form after the protein synthesis occurs in the peptides that are present in the venomous secretions of various animals. This conversion leads to the alteration of the peptide identity and function. Racemase and isomerase (epimerase) enzymes are utilized as they are created for this task. Usually, one or two amino acids of the D-form peptides are in D-form.</p>
<p>When chemist Gunther Kreil of the Austrian Academy of Sciences learned about the use of South American poisonous tree frogs (Phyllomedusa sauvagei ) during Shamanic hunting ceremonies by local Peruvian tribe (Matses), he studied this poison in detail. Participants of the ceremony first caused a burn on their chest region, then applied the poison they obtained from the frog skin over it. Diarrhea and tachycardia started within a minute, followed by a brief faintness. Once they recovered after a few minutes, they were to find themselves in a much more vigorous and exhilarated state of mind. The poison they were applying to their chest contained the dermorphin peptide, which has psychoactive, hallucinogenic effects and a D-amino acid. This peptide is a pain killer 30-40 times more effective than morphine. Among the 7 amino acids found in this peptide (heptapeptide), all are in L-form, except for one. Only the alanine, as the second in the peptide sequence, is in D-form and is produced via the isomerase enzyme from the L-alanine after the protein synthesis. G. Kreil discovered this D-form synthesizing enzyme in 2005. When this peptide was synthesized artificially in the laboratory, it did not display any biological activity or hallucinogenic effect. After a careful investigation of the case, it was found that frog skin based peptide had a D-form alanine second in its sequence; however, the one produced in laboratory had an L-form alanine. It was the presence of only one D-amino acid that made the difference in discovering the identity and function to the natural peptide in the poison.</p>
<p>In recent years dermorphin has started to be used as an illegal performance enhancer during horse races because of its pain killer feature. Horses on dermorphin can run longer and faster since they cannot feel the pain related to foot fatigue.</p>
<p>P. Kuchel of Sydney University also showed a D-amino acid presence in the peptide structured of the poison in the Platypus, a semiaquatic egg-laying mammal. Males use this poison as a weapon to fend off competitors. In 2009, Matthew Waldor and his friends at Harvard University discovered that the sugar-protein mix (matrix) called peptidoglycan found in the composition of bacterial cell walls is structured in a way to contain primarily D-alanine, D-methionine, and D-leucine. More interestingly, D-amino acids of the peptidoglycan structure were able to play a stimulatory role in coordinating the activities of other bacteria in the colony. For example, they acted as light houses in the use of florescence and helped in the formation of thin layers (bio-films) on various surfaces in bacteria. Once we understand the way D-amino acids help in communication between bacteria, it will be possible to use them as a drug. It’s possible they can be used to disintegrate bacteria that forms on teeth, in the lungs of cystic fibrosis patients, on clogs in fuel lines and water tanks, and in medical devices such as catheters.</p>
<p>D-amino acid containing peptides found in lobsters help maintain salinity levels and facilitate courtship in mating seasons. In recent years, D-amino acid containing antimicrobial peptides were discovered (bombinines) in the secretion glands of fire-bellied toad skins (Bombina sp). In this peptide, the second amino acid was in the D-form (D-allo-isoleucine). Two different peptides were found containing D-amino acids in the second position of the amino acid sequence of the poison secreted by Platypus males.</p>
<p>One of the reasons for D-amino acids to exist in animal poisons is that peptides containing D-Amino acids can not be easily degraded by the proteases (peptide bond breaking enzyme) of the host or opponents. Even though proteases can quickly and easily digest proteins composed of L-form amino acids, they struggle to do so with peptide bonds between D and L form amino acids. Pharmaceutical companies are trying to add D-amino acids to the peptide-structured drugs to prevent the quick degradation of peptides and proteins used for treatments when ingested. However, the addition of a D-form amino acid brings the high possibility of a situation that changes the function of a peptide or protein, or causes the loss of a protein. Nonetheless, specialists in this field point out that at least some amount of the D-amino acids that are produced by trillions of bacteria found on the skin, in the digestive track, and among other parts of the body can still be utilized for human health and convenience.</p>
<p>The D-serine of the mammalian nerve systems (glial cells and neurons), the D-aspartate of the neuro-endcorine, endocrine tissues, and testicles, and the D-alanine and D-aspartate amino acids of aquatic animals are abundant. D-Serine in the brain is synthesized by the conversion of L-serine into D-serine by the serine racemase enzyme. D-aspartate is in charge of hormone synthesis and secretion, and the regulation of spermatogenesis, and is produced by aspartate racemase and degraded by D-aspartate oxidase. It is also predicted to play role in the synthesis of hormones such as melatonin and testosterone.</p>
<p>As of now, four enzymes have been detected to be in charge of D-amino acid metabolism in mammals. How these are controlled is still unknown.</p>
<p>Publications pertaining to the association of epilepsy, schizophrenia, and bipolar disorders with enzymes in charge of D-amino acid synthesis and break down have increased in recent years. From this point of view, serine racemase and D-amino oxidase can be used to develop new potential drugs regarding the treatment of similar NMDA receptor associated diseases.</p>
<p>The first data demonstrating the use of D-amino acids in saliva in organs outside of the human brain was obtained by Y. Nagata and his team at the University of Nihon, Tokyo. A team led by Kenji Hamase of the Kyushu University discovered high levels of D-alanine storage in the beta cells of the rat pancreas. Kuchel, who discovered the enzymes converting the L-amino acids in to D forms in duck-billed Platypus poison, also found similar enzymes in the hearts of mice and humans. According to Kuchel, the physiological roles of those in humans remain to be unknown.</p>
<p>As a result, the common feature of toxins and antimicrobial peptides that are produced and secreted by animals is to contain D-amino acid. These peptides can be the source of a potential drug in the treatment of diseases such as cystic fibrosis, schizophrenia, and macular degeneration of the eye.</p>
<p>These prove that, especially in biology, exceptions are common; life is enriched via examples of extraordinary lives, processes, and mechanisms in unexpected places by unpredictable molecules or interesting reactions that can’t be predicted. Such discoveries help deepen our wonder at the intricacy and wisdom of creation.</p>
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		<item>
		<title>Creation of the Zygote (Nutfah)</title>
		<link>https://fountainmagazine.com/all-issues/2011/issue-81-may-june-2011/creation-of-the-zygote-nutfah/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sun, 01 May 2011 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 81 (May - June 2011)]]></category>
		<category><![CDATA[asked]]></category>
		<category><![CDATA[cell]]></category>
		<category><![CDATA[child]]></category>
		<category><![CDATA[egg]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[fluid]]></category>
		<category><![CDATA[genetics]]></category>
		<category><![CDATA[man]]></category>
		<category><![CDATA[nutfah]]></category>
		<category><![CDATA[prophet]]></category>
		<category><![CDATA[radiata]]></category>
		<category><![CDATA[resembles]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[seminal]]></category>
		<category><![CDATA[sperm]]></category>
		<category><![CDATA[sperms]]></category>
		<category><![CDATA[surpasses]]></category>
		<category><![CDATA[woman]]></category>
		<category><![CDATA[zona]]></category>
		<category><![CDATA[zygote]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2011/issue-81-may-june-2011/creation-of-the-zygote-nutfah/</guid>

					<description><![CDATA[As all the living beings, human being is also created from a male and a female. Gametes (germ cells) of male and female are being coupled at the widest point of cervix within a time span of 12 to 48 hours and thus resulting in the formation of a new and different human zygote. Although [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>As all the living beings, human being is also created from a male and a female. Gametes (germ cells) of male and female are being coupled at the widest point of cervix within a time span of 12 to 48 hours and thus resulting in the formation of a new and different human zygote. Although 300 to 600 million sperms set off at the beginning of this period in order to meet with ovule, only the predestined one of them enter into the egg. For insemination to be possible, an average of 400 million sperms should be available at every ejaculation. Only 300 to 500 of these sperms would reach at the spot where they couple with the egg (ovum) in tubes, for as much number of sperms as possible should encircle the egg in order for the zygote to be formed. In case the number of ejaculated sperms would be around 60 to 70 million, only 60 to 70 of them would reach at the spot where they couple with the egg in tubes and this is one of the reasons of male infertility.</p>
<p>The 300 to 500 sperms which strive to enter into egg meet with the cell layer (corona radiata) which is being serially positioned around the zona radiata. A liquid is secreted from this zona radiata which punctures the euchromosome<sup>1</sup> placed on tip of sperm. Each of various enzymes set free following the puncture of euchromosome is assigned to overcome a separate obstacle before the sperm. Duty of the hyaluronidase enzyme, for instance, is to puncture the outer cell layer (corona radiata) which is assigned to protect the egg. Resultantly, the sperm passes through this cell layer and sticks onto the zona radiata (zona pellucida). The quasi-trypsin dissolutive (proteolytic) enzymes are employed for overcoming the zona radiata. Only one or rarely two of the few sperms which stuck onto this zona radiata manages to penetrate into the egg. It has been estimated that plurality of sperms around the egg, contrary to their rarity, facilitates their entry into the egg.</p>
<p>The sperm penetrates into the egg with its tail but tail membrane stays outside. The protective membrane of the ovum (zona pellucida) starts diffusing calcium within the very first minutes of sperm’s penetration and resultantly, granules are released, receptors are exterminated and the egg becomes structurally transformed. Consequently, a thick layer is formed over the protective membrane (zona pellucida) for prevention of penetration of another sperm.</p>
<p>Following the sperm’s penetration into egg (cytoplasm), the “fusion” process starts. Fusion is the unification process of sperm and egg cells (pronuclei) each of which are separately containing 23 chromosomes. Thus, construction of a genetical library which is containing 46 chromosomes and being prerequisite of formation (creation) of a new human baby is completed. Afterwards, the first mitotic division gives way to a double-celled zygote and the embryo starts forming while settling into the secure base of the uterus. As the outcoming child is going to be a mixture, i.e., a genuine and particular blend of the genetic codes available in the inherited gene pool, he/she will have resemblance to his/her parents and thus to their reciprocal kins (paternal and maternal grandparents, uncles and aunts and etc.).</p>
<h3><b>Prophet Muhammad and Genetics </b></h3>
<p>Prophet Muhammad, peace be upon him, pointed in his various sayings and explanations to the fact that the baby in mother’s womb carries a number of genetic features (characteristics) which are being inherited from the parents:</p>
<p>When a Jewish person asked Him, “what is man created from?” he replied: “Man is created from a blend (mixture) of zygotes of both man and woman.” Then the Jew said: “Moses as well said the same before you.”<sup>2</sup></p>
<p>Prophet Muhammad, peace be upon him, also shed light onto the fact of resemblance or inheritance of character by way of genes:</p>
<p>“Is bathing a must for women?” asked Umm Sulaim to the Prophet.</p>
<p>“Yes, it is a must when her seminal fluid outflows and seen,” he replied.</p>
<p>“Do women have wet dreams?” she asked.</p>
<p>“May God grant you goodness! How otherwise a child resembles to his/her mother?” He replied.<sup>3</sup></p>
<p>….</p>
<p>As seen and understood by His above hadith (saying), He who was the great teacher of mankind was the first person who said that women do also see wet dreams.</p>
<p>He has also been the first person who articulated the concept of “dominancy,” which was not understood before 1850s.</p>
<p>He said:</p>
<p>“The child resembles to either side of the parents whose seminal fluid comes to the fore and surpasses the other’s in mother’s womb during the intercourse. If there is an equilibrium, then, resemblance is also in equilibrium for both sides.”<sup>4</sup></p>
<p>“If, during the intercourse, seminal fluid of the man precedes and surpasses that of the woman, then, the child resembles to the father, and if semimal fluid of the woman precedes and surpasses that of the man, then, the child resembles to the mother.”<sup>5</sup></p>
<p>“If seminal fluid of the woman surpasses that of the man, then, the child resembles to his/her maternal uncles, and, if seminal fluid of the man surpasses that of the woman, then, the child resembles to his/her paternal uncles.”<sup>6</sup></p>
<p>In another one of His sayings, He points out to the fact that the recessive characters (features) in the grand ancestorial gene pool would dominantly and collectively emerge after following a couple of generations:</p>
<p>“A man having a blackish baby boy approached and said to the Prophet:</p>
<p>“I am suspecting my wife.”</p>
<p>“Do you have camels?” the Prophet asked him.</p>
<p>“Yes,” he replied.</p>
<p>“Then, how are their colors?” The Prophet asked.</p>
<p>“Red.”</p>
<p>“Is there any one with grey color among them?”</p>
<p>“Yes, there is.”</p>
<p>“Then, where did this grey color come from?” asked the Prophet.</p>
<p>“Presumably from a line of its ancestors,” the man responded.</p>
<p>“Here you are! This child of you is also presumed to be coming from a line of your ancestors,” the Prophet told the man.<sup>7</sup></p>
<p><em>Dr. Arslan Mayda is a medical doctor at Sifa Hospital in Izmir, Turkey.</em></p>
<h3><b>Notes and References</b></h3>
<p>1. An euchromosome zone enriched by lysosome enzymes is noticed on stem of a mature sperm cell. The lysosome enzymes penetrate into the egg cell and impregnate it.</p>
<p>2. Ahmad Bin Hanbal, Aynee, Ramouz Al Ahadeeth, Kanz Al Ummal, Jami’ul Saghir</p>
<p>3. Bukhari, Muslim, Abu Dawoud, Aynee, Ahmad Bin Hanbal.</p>
<p>4. Muslim, Ibn Majah.</p>
<p>5. Bukhari, Ahmad Bin Hanbal.</p>
<p>6. Bukhari, Muslim, Abu Dawoud.</p>
<p>7. Abu Dawoud, Muslim, Ahmad Bin Hanbal, Ibn Majah.</p>
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		<title>It&#8217;s Me Peter, your Pancreas!</title>
		<link>https://fountainmagazine.com/all-issues/2009/issue-67-january-february-2009/its-me-peter-your-pancreas/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Thu, 01 Jan 2009 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 67 (January - February 2009)]]></category>
		<category><![CDATA[beta]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[diabetes]]></category>
		<category><![CDATA[digestive]]></category>
		<category><![CDATA[duodenum]]></category>
		<category><![CDATA[duty]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[function]]></category>
		<category><![CDATA[glucose]]></category>
		<category><![CDATA[glycogen]]></category>
		<category><![CDATA[insulin]]></category>
		<category><![CDATA[level]]></category>
		<category><![CDATA[liver]]></category>
		<category><![CDATA[pancreas]]></category>
		<category><![CDATA[peter]]></category>
		<category><![CDATA[secrete]]></category>
		<category><![CDATA[See-Think-Believe]]></category>
		<category><![CDATA[stomach]]></category>
		<category><![CDATA[sugar]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2009/issue-67-january-february-2009/its-me-peter-your-pancreas/</guid>

					<description><![CDATA[Peter, I am not so big as other organs like the liver, heart, and lungs; it is difficult to notice me most of the time. But whether we are large or small, no organ is superior to another; we are all just units of a perfectly created whole. None of us can function without the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Peter, I am not so big as other organs like the liver, heart, and lungs; it is difficult to notice me most of the time. But whether we are large or small, no organ is superior to another; we are all just units of a perfectly created whole. None of us can function without the other organs.</p>
<p>I hang between your stomach and your duodenum under it, attached to the intestinal mesenteries. I have two different identities in terms of my structure and function. I carry out two very different duties as a compound gland made up of both exocrine and endocrine tissues. So, I am granted a very special structure and chemical abilities to function well. One of my duties is related to the physiology of digestion: I break up the food passing from the stomach to the duodenum by pouring on it the four types of digestive enzymes I have been enabled to produce. These juices are carried through a tiny pipe to your duodenum. Two of them are used for breaking up proteins, one for carbohydrates, and one for fats. You don&#8217;t even realize it! As the food you take in passes from the stomach to the duodenum, my enzymes begin flowing faster. This is a very fine balance: while food is being digested, neither the enzymes should be wasted, nor should your intestinal walls be harmed. I don&#8217;t control the release of the enzymes. That duty is given to two hormones produced in your intestinal mucosa by the stimulus of the vagus nerve. When those hormones reach me by the bloodstream, my cells are stimulated and they secrete water, bicarbonate, and the digestive enzymes I mentioned and they flow into your duodenum through my duct.</p>
<p><span id="more-993"></span></p>
<p>My second job is the production of insulin and glucagon hormones, as the endocrinal pancreas. My cell clusters, which are also known as islets of Langerhans, have different types as separate groups, which you call alpha and beta. The insulin, which is produced by my beta cells, is used for regulating the glucose level in your blood. The duty of insulin is to stimulate your body cells to take the glucose in your blood and use it.</p>
<p>After you have a meal, the carbohydrates in it are broken down into glucose molecules, pass into the blood, and increase your blood sugar. For your body to function in a healthy way, the amount of glucose should be around 100mg/ml (it varies from 80–120). When the level is above the normal value, I secrete insulin. In this way, the sugar is carried to your cells and burned to produce energy, and its increase in your blood is brought back under control. Also, insulin helps you to store sugar in fat tissues and to turn them into fatty acids, and it slows the breaking down of fatty acids. Moreover, insulin helps you to make protein in your body by holding amino acids within your muscle tissues and storing glucose in your liver and turning it into glycogen.</p>
<p>The failure of my beta cells to secrete insulin is a serious problem; the consequence is &#8220;diabetus mellitus,&#8221; or what we commonly know as diabetes. A person with this disorder must abstain from various delicious foods and drinks. In cases where a strict diet does not solve the problem, patients may have to take insulin shots every day. Diabetes can cause many complications by damaging your nerves and blood vessels; I won&#8217;t go into types of diabetes so I don&#8217;t get sidetracked too much. I just wished to make a point: even a substance produced by a tiny cluster of cells can upset the functioning of many of your mechanisms. After having a meal, put your hand to the left of your abdomen below the stomach and remember what a blessing I am!</p>
<p>As for the glucagon hormone I secrete from my alpha cells, it does just the opposite of insulin and causes the sugar stored in your cells to be released into your bloodstream. When your blood sugar decreases-due to hunger, overwork, exercise, and so on-it causes the glycogen in your liver to be used in order to increase the level of your blood sugar. As adrenalin secreted by the adrenal glands helps glycogen to be broken down and to be released into the blood as glucose, they function as an integrated system. Glucagon also slows down the synthesis of glycogen, and it accelerates the break-up of proteins and fat metabolism. I think now you get it, Peter. Insulin and glycagon are parts of a biological feedback mechanism controlling one another. People discovered all these facts after years of lab research; now do you see how ridiculous it is to see me as a work of blind chance?</p>
<p>Like any other organ, I can also contract various diseases. The most common ones are acute or chronic inflammation, tumors, and cysts. I am easily troubled with inflammation in people with alcohol habits. Since enzyme secretions-and therefore digestive processes-are then not carried out properly, some undigested fats and fibers with proteins are excreted with the feces. A problem can arise with the intestines due to digestive deficiency. And if I completely fail to fulfill my duty owing to a chronic inflammation or tumor, then doctors take me out and you become dependent on insulin and a special liquid obtained from the pancreas.</p>
<p>It is sad to say that my cancer is not quickly recognized. It develops very fast and I try to keep up my duty as long as possible. Therefore, it is usually too late when diagnosed. There is nothing much modern medicine can do after it spreads. Although it is not definite yet, I suspect cigarettes play a role in my cancer.</p>
<p>As for diabetes, even though a promising method of treatment has been discovered, certain problems haven&#8217;t been overcome yet. The transplant of beta cells from the pancreas of someone who has just died-with as much tissue compatibility as possible-has had partial success. As with every other organ transplant, tissue rejection is a challenge. If the human genome project succeeds and the genetic code of the human body is thoroughly solved, it may be possible to cure diabetes by genetic engineering techniques. This is only at research level for now, but if scientists do their best, it is possible to find a way, since there is a treatment for every disease except for old age and death. You see Peter, as the vicegerents on earth, you humans are supposed to explore the secrets of the universe and appreciate the beauties you discover. I think I have said enough now. Thanks for listening, Peter!</p>
<p><em>Irfan Yilmaz is a professor of biology at Dokuz Eylul University, Izmir, Turkey.</em></p>
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		<title>It&#8217;s me, Peter, your intestine!</title>
		<link>https://fountainmagazine.com/all-issues/2008/issue-66-november-december-2008/its-me-peter-your-intestine/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sat, 01 Nov 2008 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 66 (November - December 2008)]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[break]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[energy]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[fuel]]></category>
		<category><![CDATA[functioning]]></category>
		<category><![CDATA[intestine]]></category>
		<category><![CDATA[large]]></category>
		<category><![CDATA[nutrients]]></category>
		<category><![CDATA[peter]]></category>
		<category><![CDATA[section]]></category>
		<category><![CDATA[See-Think-Believe]]></category>
		<category><![CDATA[stomach]]></category>
		<category><![CDATA[system]]></category>
		<category><![CDATA[villi]]></category>
		<category><![CDATA[walls]]></category>
		<category><![CDATA[waste]]></category>
		<category><![CDATA[water]]></category>
		<category><![CDATA[work]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2008/issue-66-november-december-2008/its-me-peter-your-intestine/</guid>

					<description><![CDATA[Peter, maybe now you will snap at me saying, “What are you trying to do? You are nothing but a set of long pipes, you are the last one to talk about itself!” But take care and do not be so quick to dismiss me; do not make a face at me for the waste [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Peter, maybe now you will snap at me saying, “What are you trying to do? You are nothing but a set of long pipes, you are the last one to talk about itself!” But take care and do not be so quick to dismiss me; do not make a face at me for the waste material I carry. You need to know first that your organs-the heart, kidneys, liver, and others-cannot work without me. Exaggeration? Not at all! So just listen to me and see for yourself.</p>
<p><span id="more-973"></span></p>
<p>Dear Peter, in order for you to understand me better, keep in mind a basic principle about the functioning of living organisms-they all depend on energy use. If no energy enters a living system, then no metabolic activity, no life function can be carried out. Think about a car without fuel. No matter how great the car is, it simply won’t work without any fuel in the tank. The human body is no different. Plants and animal products which people consume as food provide the body with fuel. However, you cannot make use of the energy in nutrients in the form in which you take them in. They need to undergo a process so that they become usable fuel for us, like crude oil being refined into gasoline to make a car work. This is roughly what my duty is. Without my functioning, you would be devoid of the energy to move a finger, and eventually die. Do you understand now how important a set of pipes I am? You just think that I look like a soft and hollow canal and misjudge me as simple. Well, I know that I don’t have such complex parts as the heart, lungs, and kidneys, but I’m created as a perfect work of art in plain design.</p>
<p>Although the hoses you use for watering your garden wear out and break in a relatively short time, my walls made of four layers keep functioning through a lifetime without any holes unless I contract a disease like cancer. My outer layer consists of a durable connective tissue, the next one consists of two sets-one horizontally and one vertically laid-of straight muscles, the next layer under that consists of glands spread in a soft connective tissue, and the innermost layer is the epithelial mucosa where the actual absorption takes place.</p>
<p>Now, let’s come to how I achieve digestion, one of your body’s vital activities. Actually, there is no place for me to take any pride in it; I’m just doing as I am ordered. Anyway, the complex processes occurring within my simple-looking walls are just fascinating! Every one of my cells producing the particular enzymes to break up each nutrient is like a separate factory. Some of these enzymes break proteins into different levels of peptides, some break the peptides into amino acids, some break fats into fat acids and glycerin, whereas some break carbohydrates down into glucose. All of these particular enzymes have their sub-branches within themselves. For example the enzymes breaking down fructose (fruit sugar), lactose (milk sugar), and starch are all different. In order for the enzymes to be effective, my inside needs to have the right pH level; the enzymes work in very sensitive conditions. To give you an idea, the enzymes in the stomach-which happens to be the second station the nutrients are destined for before they come to me-work in an acidic environment (pH: 2.5–3). In my case however, basic fluids are secreted and this strong acidity is neutralized for my enzymes to work.</p>
<p>My overall length is around 8.5 meters from the first entrance at the stomach to the last exit. The small intestine is nearly 7 meters long and the remaining 1.5-meter section is the large intestine. Although the small intestine is the longest section of the digestive tract, it is still called small since it is smaller in diameter than the large intestine.</p>
<p>The small intestine is also divided into three sections. The very short (25–30cm) and relatively thicker part right after the stomach is the duodenum. Bile-which works like detergent and facilitates breaking up fats-produced by the liver and digestive enzymes from the pancreas enter the duodenum. Thus, the nutrients are digested one step further and pass on to the second section (jejunum) and then to the third (ileum). You cannot easily tell apart these final two sections. As blood circulation is more intense in the second section, this section is more reddish and the contractions here are faster and stronger. The third section is narrower and has thinner walls. The blood circulation here is relatively lower and the movements are more limited. The thin membrane of connective tissue (mesentery) around me which attaches me to the abdomen wall and prevents me from knotting up is relatively fatty in this third section.</p>
<p>My most vital parts are the villi-tiny nipples covering the curly surface of my inner wall like a carpet. Shaped like the fingers of a glove, villi yield an enormously large inner surface. They contain a net of capillaries and lymph canals. In addition to the glands secreting the enzymes to break down nutrients, the secretion of certain glands protects me against the destructive effect of the stomach acid. Some cells secrete mucus for lubrication and protection of the passing nutrients. As some cells of the villi secrete digestive enzymes, some of my cells absorb the nutrients broken down until the final phase and pass them to the bloodstream.</p>
<p>Peter, how can some guys mistake such a splendid mechanism as a work of unconscious nature? What I’m telling you about is a manifestation of such great knowledge and might that it leaves you spellbound. I know the characteristics of foods, I know about the other organs’ needs, I adjust various enzymes and an absorption system, I fit them in a limited space… In addition, I do all these in the most ideal way, without any waste or flaw! C’mon Peter, can all these happen by themselves? Now, if I were to start telling everyone about the absorption mechanism in detail, they would probably see those cells as divine beings! The One who assigned special carrier molecules and a system for every nutrient molecule, has placed two transfer systems as blood and lymph pathways in every single one of those millions of villi! The blood pathway passes amino acids, water and salts into the blood directly, whereas the lymphatic pathway absorbs fats to pass them to the blood indirectly. After absorption, the nutrients become a property of the body and they are carried in the bloodstream to all the cells waiting for them in need.</p>
<p>Well, what about the waste then? Since everything you eat is not beneficial and usable, and some things are even toxic, they should be disposed of as soon as possible. The unabsorbed remnants are still too watery to be disposed of; sending them away as they are will be a waste of water and minerals. But don’t worry, everything is perfectly planned! Now the large intestine comes on duty. In this 1.5-meter section, the water of the waste and certain minerals are absorbed, and the waste solidifies. The large intestine is also divided into three sub-sections. The pouch connected to the junction of the small and large intestines is named the cecum and there’s the appendix at its end. This end sometimes festers and you have to have it removed in an appendectomy. Now, there’s this made-up story that the appendix was once longer since your ancestors only ate plants, that it has evolved into a shorter form for I now eat more meat, so on and so forth… Bah! Nothing is created in vain, Peter. If it didn’t have a duty, it simply wouldn’t be created. Only after some time did it dawn on them, after researchers proved that it is so necessary, that as a lymphoid organ, rich in blood vessels, it produces antibodies to fight the germs which somehow make their way into me.</p>
<p>The rest of the large intestine is the colon and the rectum. The mucosa covering my inner surface is rather smooth. It secretes mucus to facilitate the removal of waste. In addition, useful bacteria are made to work in abundance in the large intestine for your needs. These bacteria synthesize the group B vitamins like B12, thiamin, and riboflavin, along with vitamin K. You see how all the processes are carried out so splendidly? If it weren’t for vitamin K, your blood would fail to coagulate, and the slightest injury to your blood vessels would kill you. Could you ever have imagined that what looks to you like a sewage canal could produce vitamins of vital significance? Your Creator has infinite wisdom.</p>
<p>Peter, now you may wonder how the acts of this organ which resembles a long hose are regulated, how the nutrients inside are propelled, and then thrown out. To put it briefly, the “willful” part of your brain does not even know about it. Indeed, if it knew, it would be constantly busy with me and unable to do anything else.</p>
<p>Under the control of the autonomous nervous system, the straight muscles of my walls gradually contract in waves-this is squeezing act is called peristalsis. The nerve fibers connected to me fall into two basic categories-sympathetic and parasympathetic. As the sympathetic fibers pressure me to slow down, parasympathetic fibers stimulate me to act. Thus, I try to keep a balanced functioning between these two opposite effects. When the waste material I propel this way assumes a state to be disposed of, it reaches the rectum, and when the walls here strain, I make a natural call to you that I need to get rid of garbage. This is the step where your will has a partial interference.</p>
<p>Colon cancer, which troubles many people today, appears in this final section. The major reason is consuming too much meat and fatty foods, lack of movement, and leading a stressful life. When these are combined, I fail to function properly. If you want to help me at that, you should consume fiber-rich foods such as fruit and vegetables, and also lead a peaceful life. My web of nerves is amazingly rich and complex. Therefore, I am sensitive to nervous changes. If you feel down or sad, and if you suffer too much stress, I begin to go into spasms. Then I fail to dispose of waste, the toxic material inside me begins to damage my inner walls and eventually increases your cancer risk. Therefore, you’d better take up the habit of a glass of warm water when you get up in the morning, and try to have regular meals at the same times of the day. Most importantly, always have fresh green vegetables on your table, reduce meat intake… and it would be great if you could afford to consume olive oil rather than any other.</p>
<p>Hey, wait! I was about to forget the most important point. If you don’t have any peace of mind, all of these will be useless. This doesn’t mean that you will never worry; after all, this world is a testing ground and you are a human being like anyone else. However, if you give in to troubles and get overcome by feelings like panic, fatigue, and hopelessness, then my functioning will be upset. So, troubles faced with active patience and effort without giving up hope do not harm me much.</p>
<p>Peter, I do not wish you to wait until you see colon cancer patients disposing of waste through a hole in their belly into a plastic bag before you feel grateful for the blessings you enjoy. Actually, maybe I have told you at most a tenth of what I know about myself. Anyway, I think even this much will give you an idea of what a work of art I am. Thanks for listening to me, Peter!</p>
<p><em>Irfan Yilmaz is a professor of biology at Dokuz Eylül University, Izmir, Turkey.</em></p>
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		<title>It&#8217;s me, Peter, your Stomach!</title>
		<link>https://fountainmagazine.com/all-issues/2008/issue-64-july-august-2008/its-me-peter-your-stomach/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Tue, 01 Jul 2008 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 64 (July - August 2008)]]></category>
		<category><![CDATA[acid]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[day]]></category>
		<category><![CDATA[eat]]></category>
		<category><![CDATA[eating]]></category>
		<category><![CDATA[enzyme]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[full]]></category>
		<category><![CDATA[heart]]></category>
		<category><![CDATA[important]]></category>
		<category><![CDATA[intestines]]></category>
		<category><![CDATA[layer]]></category>
		<category><![CDATA[life]]></category>
		<category><![CDATA[people]]></category>
		<category><![CDATA[See-Think-Believe]]></category>
		<category><![CDATA[start]]></category>
		<category><![CDATA[stomach]]></category>
		<category><![CDATA[system]]></category>
		<category><![CDATA[time]]></category>
		<category><![CDATA[walls]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2008/issue-64-july-august-2008/its-me-peter-your-stomach/</guid>

					<description><![CDATA[Dear Peter, when your heart was telling you about itself in the previous issue (and perhaps you got a bit annoyed with him) I realized that it was talking for your own good. It not only was giving you advice about your health, but it was also directing you to the horizons of thought that [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Dear Peter, when your heart was telling you about itself in the previous issue (and perhaps you got a bit annoyed with him) I realized that it was talking for your own good. It not only was giving you advice about your health, but it was also directing you to the horizons of thought that will lead you to think of the True Owner of your heart and Who gave it to you as a gift. To tell you the truth, I really liked this and thought that I too should have a chat with you. If you could spare me a few moments and listen to me I hope that you will benefit both spiritually and emotionally.</p>
<p><span id="more-935"></span></p>
<p>I have been placed under the cavity of the chest. So that we do not harm each other, the Creator has placed a membrane between me and my neighbors, the heart and lung; I can hear them, but cannot see them. They are further protected by the rib cage, because they are more sensitive than I. Of course that does not mean that I am without protection. Our Lord has placed all of us in the most appropriate way. If I had bones covering me you would have a lot of difficulty eating and drinking and since you could not store what you eat you would need to eat little portions throughout the day. But since I have been placed in the stomach cavity and all the walls are flexible I can easily store all that you eat and drink until you digest them. This means that you are busy with eating only at certain times, allowing you to spend your time with other things.</p>
<p>I look like a kettle and this rather simple-looking shape might make you undermine my skills. It is for this reason that some people speak of me in a rude way, describing me as “a sack-like organ.” To understand how important I am, ask those with stomach ulcers or stomach cancer. God forbid, should I stop functioning; life would become a living hell. Each drop that you drink and each morsel you eat would be like poison and all of the world’s pleasures would vanish.</p>
<p>My walls, which seem like a simple sack, are made of four layers of special tissue. On the outer layer there is a strong tissue, below this are layers of muscle that have been placed vertically and horizontally in a diagonal manner, and under this there is tissue engulfed in a flexible layer and a final lining called the epithelium. Of course, we should not forget the web of blood vessels and nerves that nourish these thick walls. My system of nerves is such a complex system that you would be amazed; it resembles a second brain and it is aware of your whole body without you being aware. When you hurt your foot or you are upset with the slightest thing or laugh because of joy I am affected by this. This nervous system is so sensitive that it affects all my actions and my digestive excretions.</p>
<p>It is through this nervous system that I control my actions and my excretions when the scent of the food comes and you are getting ready to eat, saving you trouble after you have eaten. I can also be easily trained. If you can stick with it you can get me used to a new life after three days. Some stomachs are used to three meals, while others are content with two or one meal a day. My recommendation is that you get me used to two meals a day.</p>
<p>Not a lot of chemical decomposition can occur in the mouth, so all the nourishment you have eaten needs to pass through me before it is digested by the intestines and it becomes part of your body. What happens is that the things you have eaten are broken up mechanically into little pieces by the teeth so that I can accept them. If you hurry and swallow without chewing and do not soften the morsels you tire me out. In addition to this, if the morsels are sharp or too large they can rip the walls of the esophagus and make them bleed. It is best to chew the morsel 30 times, but unfortunately most people do not do this. They send me mouthfuls after having only chewed on it once or twice. They do not realize that they are full and therefore eat too much, disturbing the balance. If you eat slowly I will let the relevant section of the brain know and the feeling of hunger will stop after you have received enough nutrients. In this manner you do not tire me out too much and the nutrients do not go to waste. If you eat too fast I will be full before I get a chance to bring to the surface the molecules that give the sensation of being full and there will be no room for water or air, which allow me to move comfortably.</p>
<p>There are three different types of cells on the mucous layer that lines the inner layer of my walls and which is in contact with the food. One of these excretions is hydrochloric acid (HCl). This acid, which can dissolve even a piece of rock, is used not only to digest all the meat and proteins, but it also kills any bacteria that may come with the food and beverage. Without this acid the pepsinogen enzyme, which breaks down the protein, cannot be activated. The pepsinogen enzyme also synthesizes some other cells. This enzyme cannot function on its own and cannot be excreted if I do not have food in me. It starts to be excreted together with the hydrochloric acid as soon as I start to be filled with food. So how is it that such a strong acid and protein digesting enzyme do not harm my walls? My Creator has provided my lining with a temporary protective layer. The goblet cells that excrete this protective mucous are so sensitive that they excrete a protective liquid that coats it. Every day I sacrifice one and a half million cells to these enzyme and acids. In other words, every three days my inner layer is destroyed by these corrosive enzymes and acids. But thank God, I have been given me such a revitalizing strength that each day this lining is renewed with new cells.</p>
<p>Sometimes, if there is a problem with the excretion of this protective liquid, the acid and enzyme can start to eat at the stomach walls, leading to blood leaking from the arteries that are in the outer layer; this is known as an ulcer, a wound on my walls. Nervousness and tension affect the excretions in me, and therefore people who have a nervous character can develop ulcers more easily than relaxed people. The best thing to do is to live a life where one faces things with patience, neither being too panicky nor too happy, but living in a balanced and mature way. If you try to live in a balanced way then you will maintain order in the stomach and I will be happy.</p>
<p>You cannot move the muscles of my walls like you can your arm or leg muscles. The muscles are commanded and start working according to orders from an autonomous nervous system that you are not even aware of. An important feature of these muscles is that they work slowly, but take a long time to get tired. At the same time, they are very susceptible to growing if you do not take care of yourself properly; if you are not careful I can swell up quickly like a balloon. The evil side of human character has a very close connection with me; so you have to be very careful not to eat and drink too much and consume unlawful food. Otherwise, you might become weak and be easily misled and consequently this makes me nothing more than a waste container and then I become a pest.</p>
<p>Let me tell you some of the things that I do not like. At the top of the list is very hot or very cold food or beverages. Both ruin the enzymes and make them dysfunctional. The best condition for enzymes to work is at your body temperature-that is 36-37 degrees. There are more scientists today than before who think that overly hot or burnt food can cause my cells to turn cancerous. If you heat very cold items in your mouth and then swallow you protect me from getting cold – because if I get cold I contract and my working balance becomes dysfunctional so that I am no longer able to do my job.</p>
<p>When I finish my job of extracting the nutrients and treating them with the enzymes the food takes on a liquid form. When the food has achieved the desired texture I send it through to the intestines that are right below me. In this regard, I am like this transitory worldly life, which is nothing more than a two-door guesthouse-one door for entrance and the other door for exit. I never retain anything in me-I receive from one end and send it out the other. There is no door between myself and the esophagus, so I can take out what is in me if I have to by vomiting. At first, this vomiting reflex might seem a bad thing and you might wonder why there is nothing to prevent this? But let me remind you of something, what if you mistakenly eat something poisonous or something that has gone off, what would you do if you could not vomit? You would have to be taken to hospital so that you do not die of food poisoning and an incision would have to be made in the stomach; I would have to be cleansed out, but by this time you might have died. However, if I feel that something you have eaten is bad I can remove it. But with the gateway that is placed between myself and the intestines I am able to stop the food in the intestines from coming back to ruin the acidic atmosphere in me, as the enzymes in the intestines work under more neutral conditions. My acidic structure would disrupt the intestine’s enzymes. In particular, if the bile salts excreted from the liver and the pancreas enzymes should spill into me the situation would be very chaotic.</p>
<p>Another important piece of advice I can offer to you Peter is not to play any sports when I am full and not to strain yourself. The thick muscle lining on the walls requires a lot of blood to move. After eating a significant amount of blood is withdrawn from other parts of the body and sent to me. If you try to be active in this state you will suffer, as the rest of your organs will not be nourished properly and stress will be put on your heart.</p>
<p>Here’s another secret I’m going to let you in on: the more you fill me up without thinking about whether it is necessary and lawful or not, the more likely it is that you will make spiritual mistakes. Your spiritual well-being and health are inversely proportional to a full stomach. If you make me grow too much all your veins, starting with your heart, will start to gather fat and therefore their functions will slow down. Also your spiritual side will be dulled. Actually it is enough for a person to eat only what they need to survive. Serving your senses of taste and eating within the allowed parameters by remembering the Giver will not only give me peace but will also take you to spiritual horizons. After the food passes through your mouth it does not make much of a difference to me whether it is sweet or salty. Therefore, if you can take charge of your mouth, which acts as a gatekeeper, you can protect yourself from waste and from putting on extra kilos.</p>
<p>Some time ago some people would laugh at my above advice, and they would say, “Good food is the backbone of life and one should feed well.” But now modern medicine and dieticians have started to give the same advice I have been giving for years and they state that eating enough for sustenance is adequate. Most illnesses arise from over-eating; good food may be the backbone of life, but too much of it is a prescription for an early death.</p>
<p>In particular, with the dietary change that you make during the month of Ramadan, I and my team are able to renew ourselves; it is like a fitness camp that prepares us for a new term. This is an important need for us to start the new season. The time for this is approaching. I expect you will use your will power and allow me to rest as commanded. To continue with your life you need me to provide you the nutrients and energy, because without me even your heart could not function. At the root of all biological sustenance there is a need for food intake. Accordingly, I am like a double bladed sword. You should neither neglect me nor indulge me too much. I hope that you will display this balanced outlook and behavior.</p>
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		<title>Curative Cherries</title>
		<link>https://fountainmagazine.com/all-issues/2008/issue-62-march-april-2008/curative-cherries/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sat, 01 Mar 2008 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 62 (March - April 2008)]]></category>
		<category><![CDATA[antioxidant]]></category>
		<category><![CDATA[antioxidants]]></category>
		<category><![CDATA[benefits]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[cherries]]></category>
		<category><![CDATA[cherry]]></category>
		<category><![CDATA[compounds]]></category>
		<category><![CDATA[electrons]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[free]]></category>
		<category><![CDATA[fresh]]></category>
		<category><![CDATA[fruit]]></category>
		<category><![CDATA[fruits]]></category>
		<category><![CDATA[health]]></category>
		<category><![CDATA[Health & Medicine]]></category>
		<category><![CDATA[improve]]></category>
		<category><![CDATA[juice]]></category>
		<category><![CDATA[milligrams]]></category>
		<category><![CDATA[radicals]]></category>
		<category><![CDATA[rich]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2008/issue-62-march-april-2008/curative-cherries/</guid>

					<description><![CDATA[Fruits of various kinds in abundance, such as dates in sheathed clusters, bananas piled one above another, grapes, olives, figs, pomegranates, and cherries with their abundant blossom and fruit, are mentioned in the Qur’an. Among many references to the people of happiness and prosperity in the gardens of Paradise in bounty and blessings, the Qur’an [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Fruits of various kinds in abundance, such as dates in sheathed clusters, bananas piled one above another, grapes, olives, figs, pomegranates, and cherries with their abundant blossom and fruit, are mentioned in the Qur’an. Among many references to the people of happiness and prosperity in the gardens of Paradise in bounty and blessings, the Qur’an draws our attention to the people destined to heaven, who are “amidst cherry trees laden with fruit” (Waqi’ah 56:28). This mention of the cherry alongside various kinds of other fruits in the Qur’an draws our attention not only to the nutritional benefits but also to the medicinal uses of the cherry and its varieties. Recently, there have been studies to find out why cherries improve the quality of life.</p>
<p><span id="more-885"></span></p>
<p>Cherries are grown as one of three types: sweet, sour, or wild cherries. Alongside fresh cherry consumption, cherries are also used in juices, jams, jellies, cherry pies, cakes, ice cream, and so on. Cherries are healthful and rich in minerals. A hundred grams of cherry juice contains 246 kilocalories, 58.3 grams of carbohydrate, 3.12 grams of protein, 1 gram fat, 115 milligrams of sodium, 745 milligrams of potassium, 0.5 milligrams of vitamin C, 64 milligrams of calcium, and 81 milligrams of phosphorus. They are rich not only in folic acids, which play a significant role in producing nucleic acids and in the conversion reactions of certain amino acids, but also in potassium, which is needed for osmosis of bodily fluids and acid-base balance. Ripe cherry fruits have been widely used as a traditional medicine to relieve pain, especially in Western Europe and North America.</p>
<h3><b>Cherries as a rich source of antioxidants </b></h3>
<p>Antioxidants are vitamins, minerals and other compounds found in foods that can slow down the oxidation process. During the oxidation process that our body goes through in order to metabolize fats and glucose so they can turn into heat and energy, the body constantly produces free radicals as a byproduct of normal metabolism. Antioxidants help prevent the damage done to the body’s cells by such naturally occurring free radicals as super oxides. The super oxide exposure of a person weighing 70 kilograms amounts to about 1.72 kilograms on an annual basis.</p>
<p>Free radicals are unstable substances with missing electrons. They seek to balance themselves by stealing electrons. In constant need of electrons, free radicals take electrons from our healthy cells. Damage to healthy cells caused by free radicals plays a major role in the aging process as well as in the onset of many ailments. Antioxidants provide the electrons that these free radicals need so they can leave the electrons from your healthy cells alone. Protecting the body against free radicals’ mass conversion of cells, antioxidants help reduce the risk of various degenerative diseases caused by free radicals, boost the immune system and improve our health.</p>
<p>God Almighty has created all the cells of the body containing complex systems of antioxidants to prevent chemical damage to the cells’ components by oxidation. Our body is created with an ability to produce metabolic enzymes which are extremely effective antioxidant scavengers. However, the body produces more free radicals and fewer antioxidant enzymes after the late twenties. The All-Providing God has granted us many antioxidant-rich food products that may help us maintain a high quality of life, especially as this ability of the body to generate these enzymes fades dramatically with age.</p>
<p>Ranking above most fruits, cherries are an excellent antioxidant food. There are fourteen compounds in cherries with antioxidant properties. These compounds can protect the body against degenerative diseases, including cancers and cardiovascular disease. One of the more powerful antioxidant compounds in cherries is anthocyanin. In just one liter of cherry juice, there are 267–688 milligrams of anthocyanins that also give the fruit its bright red, red, purple, or violet color.</p>
<p>Recently, as awareness has been raised of most fruit and vegetables having natural antioxidants, and that cherries especially are a rich source of naturally occurring antioxidants, the use of such food products has become more common than synthetic antioxidant supplements.</p>
<h3><b>More health benefits</b></h3>
<p>Cherries offer other major health benefits. They contain the powerful antioxidant compound melatonin, which has anti-inflammatory properties and which controls daily circadian rhythms, helping to improve sleep patterns. Alongside their anti-inflammatory health benefits and improving sleep, they also provide pain relief. Research shows that the consumption of an average of twenty fresh cherries or some cherry juice is much more effective than aspirin in reducing pain caused by inflammation, arthritis or gout.</p>
<h3><b>Cultivation, consumption, and storage</b></h3>
<p>Cherry trees grow in a wide range of climatic conditions and are indeed easy to grow from seed. Once the cherry plant has established, it reaches the fruiting stage in several years.</p>
<p>Cherries can be consumed or stored in a great many ways. Alongside cherries eaten fresh or dried or the juice from the fruits, they can also be used in many dishes, especially desserts, jams, and marmalades. While buying cherries, select fresh, unblemished fruit. Besides consuming cherries as a fresh fruit item, they can also be kept in frozen fruit packs or in cans. Cherries that are to be saved can be stored in the freezer in airtight bags. Canned cherries are also available preserved in sugar syrup. Sweet cherries are particularly used in cakes and puddings. Sour cherries are generally candied or preserved.</p>
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		<title>When a Finger Moves</title>
		<link>https://fountainmagazine.com/all-issues/2004/issue-47-july-september-2004/when-a-finger-moves/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Thu, 01 Jul 2004 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 47 (July - September 2004)]]></category>
		<category><![CDATA[brain]]></category>
		<category><![CDATA[calcium]]></category>
		<category><![CDATA[cell]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[contraction]]></category>
		<category><![CDATA[correct]]></category>
		<category><![CDATA[dna]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[finger]]></category>
		<category><![CDATA[move]]></category>
		<category><![CDATA[muscle]]></category>
		<category><![CDATA[myosin]]></category>
		<category><![CDATA[place]]></category>
		<category><![CDATA[proteins]]></category>
		<category><![CDATA[reactions]]></category>
		<category><![CDATA[rna]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[simple]]></category>
		<category><![CDATA[time]]></category>
		<category><![CDATA[trillion]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2004/issue-47-july-september-2004/when-a-finger-moves/</guid>

					<description><![CDATA[The moment I want to move my finger, a large number of neurons in my brain start sending each other small electrical impulses. These impulses travel from my brain to the rest of my body through the medulla oblongata and the spinal cord. They are then delivered to my arm, which forms only one part [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>The moment I want to move my finger, a large number of neurons in my brain start sending each other small electrical impulses. These impulses travel from my brain to the rest of my body through the medulla oblongata and the spinal cord. They are then delivered to my arm, which forms only one part of my peripheral nervous system. When these small electrical impulses reach my finger, they cause the muscle cells there to contract and thereby enable my finger to move.</p>
<p>At the same time as these events are happening almost simultaneously, information from my eyes and my finger is being sent to the brain so that my finger will move in the way I expect it to. For example, if the path of my finger’s movement is somehow blocked, my brain can redirect it.</p>
<p>However, the event described above is not that simple. Starting from the neurons and continuing until we reach the muscles, every element that acts during this process displays extraordinarily complex alterations at both cellular and molecular levels.</p>
<p>Consider muscle cells, since they are moderately well understood. Upon arriving at the muscle cell, the electrical impulse causes the voltage-sensitive calcium channels in specific compartments within the cell to open and release calcium into the cell. You might remember from high school biology that muscle contraction is the result of two proteins (myosin and actin) sliding over each other. Normally, actins are masked by proteins known as tropomyosin. During the waiting period, therefore, the interaction between myosin and actin, which leads to contraction, cannot occur. This is why the muscle cell releases calcium, for when calcium is free in the cell, it binds to tropomyosin and enables it to move. As a result, actin is free to interact with myosin.1</p>
<p>After that, millions of molecules containing energy, known as ATP, bind to millions of myosin proteins, and the muscle contracts. When the contraction ends, the freed-up calcium is stored once again in specific compartments. When calcium is not present, tropomyosins again mask the actin proteins, and millions of muscle cells revert to their initial position, ready to respond to another contraction.</p>
<p>I realize that all of this is hard for the average reader to understand. However, the events that take place are even more complicated.</p>
<p>Expressions like “ATP binds to myosin” and “calcium is stored in compartments” are, in fact, simplified ways of explaining a highly complex event. Since there is a reason for everything, our cells should contain something that is performing these functions and carrying out such events. If we expand this problem to its limits, we will have to understand that each cell contains a large set of rapid and specific chemical reactions that occur constantly and yet do not interfere with one another. Based on current scientific knowledge, we can say that enzymes conduct almost all reactions in a cell, and that DNA has all the necessary information to produce enzymes. Enzymes are protein molecules that speed up and regulate all of the reactions that take place in a cell. If there were no enzymes, the reaction that a cell carries out in seconds could only be completed in thousands of years, and consequently, life as we know it would not exist. Life requires that the correct enzyme be found in the correct place and at the correct concentration.</p>
<p>Based on this, let’s revisit the above example. When the electric impulse reaches the muscle cell and calcium ions are released, this and every external and internal signal is conveyed to the DNA through a mechanism that we are just beginning to appreciate: signal transduction. Later, RNA is produced in those regions of the DNA that are responsible for producing the enzymes that enable the cell to give the appropriate answer (RNA helps DNA to produce enzymes). The synthesis of the enzyme is regulated at various checkpoints, such as during RNA production or RNA translocation out of the nucleus by other enzymes.2 ATPase, one of the many enzymes produced, makes it possible to use ATP, while another enzyme makes sure that the ATPases are in the correct location in the cell. Meanwhile, in order to sustain life, thousands of other enzymes conduct various reactions at the correct time and place. Therefore, when I move my finger, the number of active elements increases enormously.</p>
<p>Let’s look at the finer points of the cell. Using a simple calculation, in which each number is much smaller than the actual number used, if we assume that one million cells perform some kind of action from the reception of the first impulse in the brain until the time the muscle contracts, and if we calculate that one thousand reactions occur in each of these cells, this means that one billion reactions are performed for the simple action of moving a finger. One billion reactions, in just one second. And at the same time, my heart is beating, new blood cells are being produced, my eyes are sending visual information to my brain, my kidneys are filtering my blood, my lungs are exchanging old air with new, fresh air, my digestive system is supplying the necessary nutrients to my blood stream, and much, much more. Moreover, all of these are continually taking place. The fact that all of these actions are occurring, again based on a very rough and simple calculation, means that maybe one trillion reactions are occurring every second. As a result, a person might feel that it is quite possible, at any instant, for this perfect machine-the human body-to fall apart.</p>
<p>Realizing this, one might actually find it hard to believe that he or she is really alive. For example, I would never believe that such a machine would work if I did not have the empirical knowledge that it does work. How, for example, can I believe that I can produce one trillion reactions every moment and never confuse one with another, that it takes one billion reactions to move my finger, and that one trillion gears are working by themselves without making any mistakes?</p>
<p>With this idea in mind, I see the following lines in Epitomes of Light: “Also, since a building that contains every kind of artwork and riches cannot exist without having been built by someone, the existence of this universe is intimately connected with the existence of the Builder. If someone thinks carefully, it is impossible to accept one without the other.”3 Upon reading these words, I start to realize that all of these gears are not working by themselves, but rather that every second all of the trillion gears are being regulated by the One for whom nothing is difficult.</p>
<p>Suddenly, I remember that whenever the names of God are recited, I hear the name al-Hayy right next to al-Qayyum: God is He besides Whom there is no god; He is al-Hayy (the Ever-Living), al-Qayyum (the One Who sustains and protects all that exists) (Qur’an 2:255). Putting al-Qayyum next to “life” indicates, at least to me, that every living being is kept alive at each instant by al-Qayyum. If His control over each person’s existence were to be lost for even one second, one trillion gears would become irreversibly mixed up and the body would fall apart instantly. While thanking God for all that He has given me, I realize that I cannot thank Him enough for even one gear.</p>
<h3><em><b>References</b></em></h3>
<ol>
<li>Harvey Lodish et al., Molecular Cell Biology, New York: Scientific American Books, c1995, 1027-29.</li>
<li>Lewin, Benjamin, Genes VI, Oxford, NY: Oxford University Press, 1997, 847.</li>
<li>Nursi, S., Epitomes of Light: Mathnawi al-Nuriya: The Essentials of the Risale-i Nur, Kaynak A.S., 1999.</li>
</ol>
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		<title>The Miraculous World of Oxygen</title>
		<link>https://fountainmagazine.com/all-issues/2004/issue-47-july-september-2004/the-miraculous-world-of-oxygen/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Thu, 01 Jul 2004 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 47 (July - September 2004)]]></category>
		<category><![CDATA[air]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[breathe]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[electrons]]></category>
		<category><![CDATA[energy]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[genes]]></category>
		<category><![CDATA[hemoglobin]]></category>
		<category><![CDATA[hif]]></category>
		<category><![CDATA[hypoxia]]></category>
		<category><![CDATA[level]]></category>
		<category><![CDATA[mechanism]]></category>
		<category><![CDATA[miraculous]]></category>
		<category><![CDATA[molecule]]></category>
		<category><![CDATA[normal]]></category>
		<category><![CDATA[oxygen]]></category>
		<category><![CDATA[protein]]></category>
		<category><![CDATA[red]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[set]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2004/issue-47-july-september-2004/the-miraculous-world-of-oxygen/</guid>

					<description><![CDATA[All living organisms require oxygen to live. As humans, we breathe to take in oxygen; if we were not to do this we would die as we would not be able to meet our energy needs. Eighteen times more energy is extracted from glucose, a basic carbohydrate, in the presence of oxygen than without it. [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>All living organisms require oxygen to live. As humans, we breathe to take in oxygen; if we were not to do this we would die as we would not be able to meet our energy needs. Eighteen times more energy is extracted from glucose, a basic carbohydrate, in the presence of oxygen than without it. Just as we tend to underestimate the beauty and miracles found around us everyday, so we take oxygen and the breathing process for granted. In this article, we will illustrate several aspects of the miraculous world of oxygen.</p>
<p>The air that we breathe consists of 78% nitrogen, 21% oxygen and 1% other gases, such as water, carbon dioxide, and carbon monoxide. First of all, the level of oxygen in the air is of extreme importance; that is, if the air were to contain 40% oxygen instead of the normal 21%, then there would be no life on Earth. Most living organisms, if not all, would die due to oxygen poisoning. Their proteins and DNA would be oxidized and become non-functional. Metals would be corroded and trees would burn at slightly higher temperatures than normal.</p>
<p>Vertebrates have been equipped with two principal mechanisms to supply their cells with an adequate and continuous flow of oxygen. The first one is the circulatory system and the second one is oxygen-carrying molecules; hemoglobin in the red blood cells and myoglobin in the muscles. The air we breathe is filtered even before it reaches our lungs. Then, it dissolves in the mucus, a highly viscous material, which coats the inside of our lungs. Next, the dissolved oxygen diffuses into the blood through alveolar cells and the walls of the capillary vessels. Finally, the oxygen is picked up by the red blood cells; these are what make our blood red. The red color is due to a molecule called heme that is present in hemoglobin and myoglobin. Every heme molecule in hemoglobin can bind four oxygen molecules together. Every oxygen molecule bound to hemoglobin increases the affinity of hemoglobin to bind to another oxygen molecule. The hemoglobin becomes saturated if the dissolved oxygen is above a certain level; this can be seen in the lungs. If the level of dissolved oxygen drops below a certain level, as can be seen in tissues like the muscles, brain, and liver, then the oxygen molecules start to dissociate from the hemoglobin. Likewise, every dissociating oxygen molecule facilitates the dissociation of another oxygen molecule from the hemoglobin. This is one miraculous design that is known to us: a molecule devoid of any wisdom and intelligence grasps a very crucial cargo where it is abundant, carries it to a place where the cargo is most needed and less abundant, and releases it. The myoglobin in the muscle tissue then binds the oxygen and serves as an oxygen backup resource for times when there is inadequate oxygen supply during exertion.</p>
<p>Fetuses have their own specific hemoglobin, called hemoglobin-F, which is different from that of adult hemoglobin, hemoglobin-A. Before birth, the fetus gets its oxygen from the mother’s blood through the placenta. The higher affinity of hemoglobin-F than hemoglobin-A to oxygen makes the oxygen exchange between the maternal and fetal blood possible. It is interesting to note that right around the time of birth the fetus switches the production of hemoglobin-F to hemoglobin-A, as this is more efficient under normal breathing conditions. Our current knowledge is insufficient to completely understand how this switch-over occurs and how it is regulated. Future studies will shed light on this complex but magnificent mechanism of regulation and this superb design.</p>
<p>Why are we so dependent on oxygen? In fact, our energy metabolism is completely dependent on oxygen. The chemical breakdown of nutrients by a dozen enzymes releases energy, which as is cannot be stored or transferred to the places where it is required. We are equipped with a second mechanism, which involves another set of different proteins that converts the released chemical energy to a more useful and transferable molecular form, called ATP. ATP, which we can think of as small packages of energy, is the main form of energy within our cells that can be readily used by all reactions that require energy. The first set of enzymes abstracts electrons from the nutrients during their chemical breakdown. These so called high-energy electrons are transferred from one protein to the next by the second set of proteins that form the electron transport chain. The final acceptor of these electrons is molecular oxygen. If oxygen were not there to pick up the electrons at the end of this chain, the last protein (cytochrome oxidase) would lead to a dead end, as it would be rendered inactive with the electrons that it is carrying. This would make this superb design of complex mechanism useless and wasteful; the synthesis of every new and active cytochrome oxidase would require more energy than is produced in one cycle of an electron transfer in the absence of oxygen.</p>
<p>It has been known for some time that cells can sense the level of oxygen in their environment. They are equipped not only with a sensing mechanism, but also with a response mechanism, by which they can survive for a short period of time. In 1995, a protein called HIF (Hypoxia Inducible Factor) was identified and was shown to regulate cellular response to hypoxia, i.e., a reduced oxygen level. HIF is a transcription factor, which induces the expression of a set of genes that are required for survival under hypoxia. Several genes encoding glycolytic enzymes are regulated under hypoxia; this allows cells to produce ATP even without oxygen. Nevertheless, oxygen-independent energy generation is very inefficient and the yield is insufficient. Another set of genes induce angiogenesis (vascularization), or the making of new capillary vessels. VEGF (vascular endothelial growth factor) is one of the best known HIF target genes that induces the formation of new vessels where expressed.</p>
<p>One of the most remarkable aspects of HIF-based oxygen sensing is that under normal oxygen levels the HIF protein is simultaneously synthesized and degraded. Only under low levels of oxygen does HIF accumulate and induce its target genes. At first sight, this continuous production and degradation of HIF may look wasteful, whereas in reality it is a very well designed precautionary mechanism. The HIF protein is marked and sent for degradation by a class of enzymes called HPH/PHD. These enzymes also use the oxygen molecule to tag the HIF protein. If there were not enough oxygen around, HPH/PHD enzymes would not be able to tag HIF. As a result HIF accumulates and induces its target genes to ensure the adequate supply of oxygen. With this mechanism cells can quickly adapt and survive. Therefore, continuous production and degradation of HIF turns out to be a necessary precautionary measure which is taken against the risk of death arising from a low oxygen level.</p>
<p>This article is by no means a complete picture of the miraculous world of oxygen, perhaps it is no more than a brush stroke on the entire picture. Yet, even this incomplete glimpse is enough to help us realize how perfectly we have been created, and how well we are taken care of. We do not have even the slightest control over any of these aforementioned mechanisms. We breathe day and night, and every breath should be taken in gratitude to God, who created us as this masterpiece.</p>
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		<title>Listening to a Fly</title>
		<link>https://fountainmagazine.com/all-issues/2004/issue-45-january-march-2004/listening-to-a-fly/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Thu, 01 Jan 2004 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 45 (January - March 2004)]]></category>
		<category><![CDATA[create]]></category>
		<category><![CDATA[creatures]]></category>
		<category><![CDATA[eat]]></category>
		<category><![CDATA[eggs]]></category>
		<category><![CDATA[enzymes]]></category>
		<category><![CDATA[flies]]></category>
		<category><![CDATA[fly]]></category>
		<category><![CDATA[flying]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[germs]]></category>
		<category><![CDATA[god]]></category>
		<category><![CDATA[larvae]]></category>
		<category><![CDATA[organs]]></category>
		<category><![CDATA[people]]></category>
		<category><![CDATA[produce]]></category>
		<category><![CDATA[See-Think-Believe]]></category>
		<category><![CDATA[wings]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2004/issue-45-january-march-2004/listening-to-a-fly/</guid>

					<description><![CDATA[&#8220;Surely, those whom you invoke, apart from God, will never create a fly even if they combine together for the purpose. If the fly takes something from them, they cannot rescue it from him.&#8221;; (Qur&#8217;an 22:73) Good day my dear friends! I know you are tired of me, I bother you so often, especially in [&#8230;]]]></description>
										<content:encoded><![CDATA[<blockquote>
<p>&#8220;Surely, those whom you invoke, apart from God, will never create a fly even if they combine together for the purpose. If the fly takes something from them, they cannot rescue it from him.&#8221;; (Qur&#8217;an 22:73)</p>
</blockquote>
<p>Good day my dear friends! I know you are tired of me, I bother you so often, especially in hot weather; but would you mind listening to me a little? I don&#8217;t understand why you are so proud! Did God create just you, and someone else created me? Some people do claim that I and all the other creatures evolved just by chance, in a process they call evolution, but I wouldn&#8217;t pay attention to them if I were you. Our Lord, God, created you and me, and the whole universe. Then why do you see me as being so unimportant? Of course, my Lord made humans superior and gave them an honorable place in this world, but this is only for those humans who recognize God Almighty and who pray to Him. If someone does not recognize the Creator, then this person will fall lower than me; I know my Lord, and I do not change my behavior. I don&#8217;t do anything but what He taught me. True, I am not tested as you all are, but I am happy with my lot. I carry out my duties obediently.</p>
<p>Although I do many useful things, most of you (except for the zoologists among you) aren&#8217;t aware of what my uses are. Some people even say, &#8220;Why has this black bug been created? It is of no use.&#8221;</p>
<p>If you just look at my wings, you can see that they are like a perfect work of art. Think about it, what would be more difficult, producing a large watch or a small and sophisticated one? Obviously producing a small watch is much more complicated. But one must remember that nothing is easy or difficult for God, He just says &#8220;Be&#8221; and He can create anything. By saying, &#8220;Be&#8221; He can create a microorganism or an elephant in an instant.</p>
<p>Just as you have organs that carry out the biological functions in your body that are necessary for your survival, I also have organs and systems in my body which carry out similar functions. The only difference between yours and mine is their structure and working principle. For instance, we both have hearts. Your heart pumps the blood to the body via the veins, and my heart pumps the blood to the spaces between my organs. You use your lungs for breathing while I have capillary tubes called trachea which transfer air directly to my tissues. The organs in my head are composed of many small particles. Each one of my eyes is created from hundreds of small hexagonal structures called ommatidia. Each has its own lens, a pigment cell that isolates it from the others, and a crystal cone. A special protein called chitin covers my body. Each one of my hairs acts as a special receiver, allowing me to detect all vibrations. Chitin is made up of a protein, which is durable and not permeable to water.</p>
<p>My mouth is shaped like a tube, while my tongue is like a sponge, helping me to taste my food. My feet, made up of chitin, are very thin and formed of many parts with a hook at the tip, making it easy for me to climb vertical surfaces.</p>
<p>There are hollow tubes in my wings, making them very light and strong. The hammer-like organs (halter organs) under my wings help me to balance while flying. There are some know-it-alls out there who claim that these organs were secondary wings that lost their function during evolution, but they seem to forget that there are many insects that have secondary wings. If this is so, why did I need to &#8220;lose&#8221; mine? It is hard to understand why these people do not try to understand reality. Actually, God created me with one pair of wings and two organs to help with balancing. These organs have nothing to do with mutations, adaptation, selection or evolution. Although my ancestors did mutate at times as all living things have done, we have never changed or evolved. Some of us are weak and some are strong; this is a rule of God. This rule is necessary for the ecological balance to be maintained. Some flies will be food for other living creatures, while some will survive to produce more flies. I have not heard of any other flies evolving into a new living creature.</p>
<p>I can fly better than you. You have imagination and knowledge, and you have the ability to improve yourselves, yet you still have not been able to invent a machine that can fly as well as I can. I can turn a somersault in a tight space. I can walk on the ceiling. I can sense the approach of your hand. I can take off so easily that I do not even need a &#8220;runway&#8221; like airplanes do before taking off. Airplanes can be used for destroying other things, but us flies help to build a better world. My Creator (God) has given me coordination in flight; I do not crash into other things and do not cause any damage while flying. The Qur&#8217;an (22:73) says: &#8220;Oh mankind! A parable is set forth, so listen to it: Surely, those whom you invoke, apart from God, will never create a fly even if they combine together for the purpose. If the fly takes something from them, they cannot rescue it from him.&#8221;</p>
<p>The Qur&#8217;an is a miraculous book; yet, unfortunately some people do not understand this yet. Even if all human beings were to work together, they would not be able to build a small &#8220;fly&#8221;. If I take something from you, you cannot get it back from me. For example, when I snatch a piece of your food, I simply pour digestive enzymes on it and it melts. These enzymes break the food into pieces and make them liquid. Then I am able to drink this liquid. Well now, it would be impossible for you to convert this food back to its original form. Let me show you my nutrition cycle on the right.</p>
<p>When someone mentions the words &#8220;flight and insect&#8221;, it is most normal to think of only one insect, the common house fly, but there are in fact many species of flying insects: approximately 90,000. Since we have wings, we are all called &#8220;diptera&#8221;. There are many of us on the earth; from this one can conclude that there will be useful as well as harmful insects among us. Some of our friends take pollen from flower to flower, making honey for you to eat. We eat a variety of foods; some eat meat, some eat vegetables, while others eat fruit.</p>
<p>My friends and I who belong to the Musca type are the most frequently encountered flies in your neighborhood. We, like the other species of flying insects, increase our reproduction rate with increases in temperature. We produce large numbers of eggs. The maggots that you see in rotten food are in fact my larvae. The female fly leaves her eggs on the food you leave out in the open. These eggs hatch in a few days, the time being longer or shorter depending on the temperature. The larvae have a great appetite for everything and they grow fast as they eat everything they encounter. Then they enter a dormant period and retreat into cocoons. After a short while, they come out with bodies that are totally different anatomically. If you were to tell this to someone without a great deal of know-ledge, they would never believe that these crawling larvae will turn into flying creatures one day. It is hard to predict or understand such a huge change. There lies a great wisdom in both our forms. For example, if we did not exist, only bacteria would be able to help decay the dead and this would take too long. But, thanks to my larvae and their presence everywhere in large numbers, this process is completed in a matter of few days. Due to their speedy consumption of decaying matter, maggots have been used often in medicine. They have been used to get rid of decaying tissue on the wounds that aren&#8217;t healing, and in this way they speed up the healing process.</p>
<p>Now, I also want to remind you of an unfairness that you do to me and all other flies. As you know, our eggs develop and spread fast during the warm summer season; each of us can produce hundreds of eggs. We go all over the place to find food and sometimes we find it in your trash or in animal droppings. Those who see us in these places mistakenly accuse us of carrying and spreading disease. But the reverse is true; we consume the germs that spread quickly in hot weather. These germs grow on food all by themselves, we don&#8217;t produce them. Germs are living creatures too, and they use their abilities bestowed on them by God to grow everywhere. All we do is clean the environment by eating them as we feed. We are able to digest germs thanks to the strong digestive enzymes that we carry. Despite what is believed, I am a clean animal. I clean myself all the time, using the digestive enzymes in my saliva. If it weren&#8217;t for me, the germs would grow and spread faster.</p>
<p>I hope that from now on you won&#8217;t try to shoo me away when you see me on your hand. Instead, I hope that you will watch how I move and observe me more closely; witness the fine art in me. When you think about me, consider what I have told you. Don&#8217;t you think that you should change your opinion about me?</p>
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