The foot is a limb that is not given much importance when compared to other vital organs such as the brain or heart. However, the foot is a very complex mechanical structure that is made of 26 bones, 33 joints, and more than 100 muscles and ligaments. About a quarter of the bones in the human body and about a fifth of the joints are found in our two feet. That is why Leonardo da Vinci described the human foot as an engineering and artistic masterpiece.

A healthy person takes about 5,000 steps a day. Given a life of eighty years, a person takes about 150 million steps throughout their life. Assuming that each step is 75 cm, a person walks about 110,000 kilometers throughout his life. This corresponds to walking around the equator about 3 times. Apart from that, a typical person stands for around 2-4 hours a day. During all these activities, the human foot carries the entire body’s weight. In standing position, body weight is supported by two feet while activities such as walking and running are done by only one foot for a certain period of time. While standing, the feet carry 100% of their body weight, while walking, this rate rises up to 150%. While walking, the foot that needs to be lifted from the ground approaches the ground again with an acceleration in the same direction as gravity. Therefore, the impact force at the moment the foot touches the ground corresponds to 150% of a person’s body weight. In cases of severe effects such as running and jumping, this force easily increases up to 5 times the body weight and up to 10 times in some people. For a person weighing 70 kilograms, this force can be 105 kg (or about 1050 Newton) in walking, and easily 350 kg (or about 3500 Newton) in running or jumping. Assuming that a person walking for an hour takes 5,000 steps, the foot pulls a total of about 500 tons of load (5,000 steps x 105 kg). In running, this figure will increase approximately three times.

The foot has been created with a wonderful mechanical and construction design that is able to consistently sustain such high loads. The bones and muscles of the foot add two different belt designs to it. One of them, the structure called the longitudinal belt starts from the heel bone (calcaneus) and ends with its metatarsal bones (Figure 1). Some researchers claim that the long arch is divided into two parts as the inner (medial arch) and the outer arch (lateral arch). However, both structures resemble bridges built in arches. The second arch on the foot is called the transverse arch. This belt is perpendicular to the long belt from the right side of the foot to the left side and is shorter in length (Figure 2).

Therefore, the foot is a marvelous structure consisting of roughly two arches. This structure of the foot can be compared to arch bridges or a dam. The arch structure is known as the strongest structure against steep loads in construction areas due to the robustness of the designs against compression forces in cases of vertical loading. Therefore, hydroelectric dams are constructed in the form of arches or arcs in order to make the most resistant model against hydrostatic pressure.

The arch structure of the foot is very flexible and can also move up and down like a car suspension and acts as a shock absorption. If there was no such structure on the foot, the impact forces during walking and running activities would be higher and cause chronic foot pain. The flatfoot complication is a result of a damage in the arch structure in the foot which comes from birth or develops afterwards. Flatfoot patients are often unable to perform long-term activities and experience foot pain as well as complications in other organs of the body.

Our feet’s arch structure is not the only factor involved in shock absorption that is designed against mechanical forces. The layer of fat on the bottom of the foot also contributes to this process. In a healthy person, this fat layer, which has a height of 2.5 cm under the heel, drops to 5-7 mm in the front part of the foot. It also helps to distribute the vertical and horizontal forces caused by standing or walking evenly on the sole of the foot. At the same time, it serves as a source of heat insulation and helps protect our feet from hot or cold surfaces. In some diseases such as diabetes, in which this fat layer melts or decreases, wounds called foot ulcers can develop because the shock absorption and load distribution get damaged. Mechanical pressure is calculated by dividing the amount of mechanical force by the surface area on which it is applied, meaning that smaller surfaces areas are subjected to more pressure. This is why very tiny needles, despite weighing almost nothing, can pierce our skin and cause pain. Similarly, damage to the fat layer under the foot causes the forces applied under the foot to act on a limited surface area. For example, the reduction of fat in the area just below the heads of the metatarsal bones reduces the “cushioning” effect in this area and causes a pressure in high values. This extra pressure can cause tissue damage along with the aforementioned foot ulcers.

Such a situation that will cause pain in a normal person cannot be felt by many diabetics. If diabetes is not well controlled, neuropathy or a “lack of feeling” may occur as a complication. Dead nerve cells become unable to feel pain which can result in people not knowing about harm that is being done to their body. Diabetic patients who develop neuropathy would not feel fatty layer damage and accompanying high pressure values whereas a typical person normally would. Untreated foot ulcers can become infected and can turn into gangrene. Since the gangrenous foot has to be cut, diabetes unfortunately causes a large number of amputations. Such amputations are sadly quite frequent throughout the world due to diabetic neuropathy. Dr. Paul Brand, who studied diabetic foot ulcers, defined pain as a gift from God that no one wanted. Sometimes, what we do not like might be better for us (Qur’an 2:216); likewise, pain can cause a lot of trouble to people but it can also alert us of dangers and harm to our bodies.

Thus, foot care is very important in diabetics. The following three actions are recommended to patients; daily inspection of the foot; daily washing; and control of the inside of the shoes. The pest, pebble, or similar hard object in the shoe that can be very harmful for diabetics with loss of sensation would be removed this way. On the other hand, when such a hard object remains in the shoes, patients may step on them repeatedly without feeling it which will likely lead to an ulcer case.

With its pain that works like a health alarm, extraordinary mechanical loads it carries, heat insulation and shock absorbing features, the human foot is a wonder of art that calls for contemplation.

Diabetes is one of the most serious public health risks today. The United Nations declared diabetes as a global threat in 2007 in order to highlight just how widespread and destructive diabetes had become.

Diabetes is one of the oldest known diseases, and was even mentioned in the ancient Egyptian, Indian, and Chinese texts. Ancient Egyptian texts defined diabetics as “… so thirsty that if they drank all the water of the Nile, their thirst would still not be quenched.” The ancient Indian and Chinese texts mention insects and flies swarming over the urine discharged by the diabetics.

Ancient scientists Al-Razi and Ibn Sina (Avicenna) made important findings about diabetes. Al-Razi linked diabetes with obesity and nutrition habits. Ibn Sina specified that no tissues or organs could survive diabetes, which additionally caused sexual dysfunctions and gangrenes.

There are two main problems that emerge in relation to diabetes:

• Type 1: Lack of adequate secretion of the insulin hormones from the pancreas
• Type 2: Non-functional and insulin-resistant tissues, regardless of adequate insulin secretion

These two types do not coexist in one patient. The first occurs mostly among children or young people. The second occurs mostly among the elderly who largely contract diabetes due to obesity. Diabetes can be detected by a surge of sugar in the blood and urine. If blood sugar exceeds a certain limit then sugar will appear in urine.

Diabetes reveals itself by a surge of sugar in the blood and the urine. It not only impairs the sugar balance of the body, but also disrupts the fat and protein metabolism. Cells fail to absorb sugar, fats, and amino acids, which in turn increases sugar, fat, and amino acid levels in the bloodstream. It can plainly be said that diabetes complications originate from an increase in fat levels, not sugar levels, in the blood. Additionally, diabetic disorders in fat metabolism cause the lethal appearance of acid levels in the blood (acidosis) and vascular stiffness (arteriosclerosis). Decrease in protein-synthesis ability among patients with long-term diabetes leads to depletion of tissues and multiple cellular dysfunctions. Consequently, diabetes originating from insulin deficiency disrupts the fat and protein metabolism along with the sugar metabolism.

The pancreatic gland is where insulin is released in our body. The surgical removal of this gland in experimental animals showed that fat levels in their bloodstreams increased faster than sugar levels. In diabetics, fat around the abdomen and hips oozes into the bloodstream, thus leading to an increase in neutral fat (triglyceride) and cholesterol levels in the blood along with an accumulation of fat in the liver.

If fats remain in the bloodstream after nutrition, then they begin to adhere to vein walls which can cause clogging and stiffness in blood vessels. That is why it is crucial to transfer fat from the bloodstream to fat storage around the abdomen and hips by means of sugar and insulin. The storage fat is called neutral oil, or triglyceride. A triglyceride molecule contains three units of oil and one unit of sugar. Therefore, almost 25% of the fat storage is sugar. Without sugar supply from bloodstream, as in the case of diabetes, the cells which by default store fat are unable to do so. Diabetes, as a serious disorder, even reverses this mechanism: fats start moving from the storage to the bloodstream, not from the bloodstream to the storage. This causes the surge of all fats including the triglycerides, cholesterol and phospholipids, and this is when the body becomes even more prone to disease.

Obesity or excessively fat-based (steatopygic) diet is one of the main causes of diabetes. People are already overweight before the disorder strikes. However, if they do not receive treatment after contracting diabetes, the diabetics start losing weight quickly and more than they should. This happens because relatively harmless fats in storage start to dissolve into the bloodstream.

The entity called metabolic acidosis, which can cause coma and death in diabetics, actually originates from the surge of fat products in the blood and the liver, not from the surge in blood sugar. In diabetics, when the cells cannot use sugar, they resort to obtaining their energy from fats. Consequently, stored fats start to dissolve and ooze into the bloodstream. Fats traveling to the liver through the bloodstream turn into acidic substances called ketone bodies (acetoacetic acid, beta hydroxy butyric acid, and acetone). These acidic substances pass from the liver to the bloodstream and are received by the cells to meet their energy needs. However, in diabetics, cells cannot convert these acidic fat products i.e. ketone bodies, into energy. Oxaloacetic acid from sugars is required for the energy production cycle called the Krebs cycle. In short, humans need sugar to burn fat. This is why it is normal for some people to feel the need to eat something sweet after a fatty meal, because they need sugar to dissolve the fats in their bloodstreams. Since the cells cannot draw sugar from the blood, they suffer from the deficiency of oxaloacetic acid to convert fats into energy. Fats and ketone bodies teem in the bloodstream and, since ketone bodies are acidic, they can cause acidity levels to surge to extremely high levels in the bloodstream which can result in a coma or even sudden death. The lethal substances here are not sugars but ketone bodies, or fat products.

The most crucial abnormality caused by diabetes is vascular stiffness (arteriosclerosis), which originates not from excess sugar but excess fat in the bloodstream. In diabetics, triglyceride, cholesterol, and phospholipid levels increase in the bloodstream due to the reasons described earlier. Fats in the bloodstream do not circulate freely; they are carried in micro-droplets called lipoprotein. The liver loads the fats onto lipoprotein “trucks” and sets them into the bloodstream to be used by the cells. However, due to insulin deficiency in diabetics, lipoproteins cannot empty their shipments of fat into fat storages. The most dangerous lipoproteins for vascular stiffness are classified as LDL (low-density lipoprotein) and HDL (high-density lipoprotein) types. HDLs are like empty trucks specially produced by the liver, which dispatches them into the bloodstream. While circulating in the bloodstream, these “trucks” collect the fat and cholesterol stuck on the vein walls like magnets and, after cleaning the inner vein walls, they return as loaded trucks back to the liver. Using the HDL “trucks,” the liver removes fat from the bloodstream. Physicians gauge the LDL and HDL levels while checking their patients for the risk of vascular stiffness. An increase or decrease in LDL rate is not good for patients, whereas high HDL rate is a positive sign.

Other causes of vascular stiffness include lack of exercise, sedentary life and work habits, smoking, alcohol consumption, obesity, overconsuming foods rich in animal fat, and high blood pressure. Vascular stiffness is one of the leading causes of cardiac dilatation (enlarged heart), cardiac insufficiency (heart failure), and heart attack. In addition to these complications, vascular stiffness may also lead to high blood pressure, cerebral hemorrhage, paralysis, kidney failure, and vascular occlusion in the brain or other organs. If not treated, almost all of these disorders result in death.

Diabetics should follow an effective treatment regime to keep their blood sugar level under control. Fasting is known to be beneficial for controlling blood sugar. If blood sugar is normal, the fats in the bloodstream will move to the storage and not damage the blood vessels. Among the elderly and the obese diabetics, any damage originating from high blood sugar does not surface immediately, and this may mislead patients. It is extremely crucial to check blood sugar in order not to fall into this error. Treatment should never be neglected. If blood sugar can be effectively reduced, it is not right to give up sugar completely in the diet. As mentioned earlier, humans need sugar for storing fats or converting fats (or ketones) into energy in the Krebs cycle.

In short, high blood fat is a more serious cause of diabetes than high blood sugar.

There are many ongoing studies into fasting, a practice prescribed across many religions. Increasingly, there is evidence to support that intermittent fasting is beneficial to human health.

The opposite of fasting – overeating – has been revealed to be a major culprit in many illnesses, including cancer, obesity, and heart disease. For many years, the medical consensus was that fasting, i.e. prolonged hunger, too, could have deleterious effects on the human body. From kidney failure to loss of muscle, fasting was believed to be harmful – thus calling into question the benefits of this widespread religious commandment.

People of faith – including Muslims – have long believed that God wouldn’t recommend a practice that was harmful to the body. The hardships and troubles that accompany a religious practice are not too extreme for people aware of their servitude to God: they regard their trials as a testament of their faith. Part of that faith is the certainty that God wouldn’t recommend a harmful or unbearable practice.

In this article, we will share with you two unknown benefits of fasting that have been recently discovered.

Regenerating stem cells

There is a substantial body of evidence showing that staying hungry during certain periods of the day heals the body’s metabolism, hastens loss of fat, decreases oxidative stress,* and improves the functions of the tissues that make up various organs including the liver, the intestines, and the brain. The first of the two new discoveries about the underlying processes, however, provides a missing piece of the puzzle by helping us understand the incredible changes hunger triggers in stem cells.

Researchers at MIT, Duke University School of Medicine, and Whitehead Institute for Biomedical Research in Cambridge published an article recently on stem cells, indicating that part of stem cell’s mystery could lie in the oxidation (burning) of fat in the mitochondria [1]. Omer H. Yilmaz and his fellow researchers found that a 24-hour fast hastens fat breakdown in intestinal stem and special progenitor cells of rats.

To run the study, Yilmaz and colleagues let the mice go hungry for 24 hours to study the state of their stem cells. They found that the functions of intestinal stem cells increased, and fat metabolism quickened, in both young and aged mice, even during early periods of hunger. They saw that the body’s tapping into fat for its energy needs maintained the health and strength of the intestinal stem cells. Moreover, they noticed that if the aged mice did not fast, they started to lose their ability to break down and use fats for energy expenditure.

The researchers obtained more interesting results as the studies progressed. It was found that a single period of hunger for 24 hours boosted renewal of intestinal cells – and the stem cell functions increased even more significantly in aged mice. Another interesting finding was that mice with damaged intestines that were fasted recovered faster than those that were fed.

“My lab is really interested in understanding how diet, in general, can be used to improve tissue function,” Yilmaz said. “One of the tissue types I study is the intestine. In my lab we study the intestine because it’s one of the largest organs in the body. It’s also a tissue that experiences rapid cellular turnover.” [2]

The intestine is lined by a single layer of cells, Yilmaz explains, that turns over every 5 to 7 days. The workhorses of the intestinal lining and this cellular turnover are intestinal stem cells. These cells must retain a high level of function or cellular health in order to replenish the intestinal epithelium on a regular basis. Intestinal stem cells are particularly important in terms of repairing intestinal damage caused by gut infections and chemotherapy, for example.

The single layer of epithelial cells needs to be renewed every 5-7 days: the aids and enzymes secreted in the intestine for digestive and absorptive activities damage cells despite the protective mucus layer, and some other cells already burst and die as they empty their secretions. Moreover, some medications, particularly chemotherapy, cause the destruction and breakdown of the epithelial cell layer. However, fast-multiplying stem cells replenish the epithelial cells. Stem cells are very active and young and have the ability to divide and multiply continuously.

Dr. Yilmaz also says:

“As we age, stem cells in the intestine as well as in many other tissues of the body, including in the blood and nervous systems, become less functional. We believe that reduced adult stem cell function contributes to some of the decline of function associated with old age. My lab is very interested in studying low-calorie interventions to delay this decline. As a field, we’ve known for over 100 years that low-calorie states such as fasting or caloric restriction can have positive effects on tissue health and aging. We’ve seen evidence that fasting during times of intestinal infections that lead to diarrhea may promote healing of the intestinal lining, for example.” [2]

This quote emphasizes the importance of the issue. Yilmaz adds that despite all this knowledge, the cellular mechanisms of this renewal have not been discovered, and he and his team are working to find out how fasting and hunger enable this recovery.

Stem cells become happy in fat!

The researchers discovered through the experiments that the stem cell function could be brought about in hungry mice by the burning (oxidation) of fatty acids in intestinal cells. When they stopped the fat metabolism through genetic engineering, they noticed that the benefits of fasting on intestinal stem cells were negligent.

In the present dietary conditions, we obtain nearly 60-70% of our energy from carbohydrates or sugar, 20% from fats and 10% from amino acids. Yet an interesting finding revealed by Dr. Yılmaz and his research team is that we essentially obtain much greater energy from using fats once we fast. According to their experiments on mice, during fasting, the intestinal stem cells in both young and aged mice switch from carbohydrates to fats as the primary source of energy, and this shift enables improvement in stem cell functions.

It is not yet known what underlies the fat metabolism that boosts stem cell functions in response to fasting, but it is observed that stem cells work better when they burn fat. The ability to metabolize fats efficiently decreases with age.

It is likely that this hastened metabolism – encouraged by certain diets, like the keto diet, where the amount of fat ingested is raised to 70% and carbohydrate intake is limited to 5% – helps with epileptic seizures and similar neurological disorders: the ketone bodies generated during metabolism of fats are used as energy sources by the brain.

According to Dr. Yilmaz, if fasting can improve the functions of intestinal stem cells through metabolism of fats, the key is the mitochondria, the powerhouses of the cell responsible for this function. Fat metabolism, or the immediate breaking down or “burning” of the fat entering the cell, is carried out in the mitochondria. Disrupted energy generation associated with aging and decreasing mitochondria can be a reason for the brain’s susceptibility to age-related illnesses. Positive developments in brain functions can therefore be viewed in connection with the correlation between fasting and the oxidation of fatty acids.

Cleaning by fasting

Just like the spring cleaning in our homes, our cells need a thorough cleaning to function properly. Wrongly folded protein particles, remains of damaged organelles, broken molecular pieces, and aged cells that can no longer divide should be disposed out of our cellular structure. Fasting perfectly performs the task of cleaning these wastes and clearing the area in the cell.

“Everything has zakat (a means of cleaning), and the zakat of the body is fasting.” (Ibn-i Majah, Siyam: 44)
“Fasting is a protective shield.” (Bukhari, Sawm: 2)

What is autophagy?

Autophagy is the compound of two ancient Greek words: auto (self) and phagos (eating). What is meant by “self-eating,” is the breaking down and recycling of protein waste and old, impaired molecules by intracellular digestive organelles called lysosomes. In this way, proteins or cellular organelles are digested and taken out of circulation. We can liken autophagy to garbage collection.

Japanese researcher Yoshinori Ohsumi’s study, which brought him the 2016 Nobel Prize for Medicine, found that the autophagy that occurs inside the cell due to fasting or starvation plays an important role in preventing ageing, infections, and tumors. If autophagy breaks down, many illnesses may be triggered, including cancer. Conversely, if autophagy activity is regular, tumors may be suppressed – depending on the stage of development and type of tumor. Cancer research has long focused on channeling these autophagic activities. Restriction of food intake through fasting shows promise: it may protect normal cells while triggering autophagy and thus increasing the effect of cancer treatments. Autophagy might offer solutions or treatment options for other illnesses, too, including inflammatory diseases [3], neurodegeneration [4], metabolic and cardiovascular diseases [5], obesity [6], and metabolic disorders.

Preclinical studies have shown that dietary restrictions by fasting contribute to the increase of a person’s lifespan and slow the development of age-related diseases such as cancer and neurodegenerative and cardiovascular diseases [7].

* Oxidative stress: The damage caused as a result of excessive proliferation of free oxygen radicals released from foods that spike blood sugar (with high glycemic index) as metabolic waste. A good example of oxidative stress is the browning of certain foodstuff such as apples, bananas, etc. sometime after they are peeled.

References

1. Yilmaz, Omer H. et al. 2018. “Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging.” Cell Stem Cell, Vol. 22, Issue 5, May 3, pp. 769–778.
2. Paige Brown Jarreau. 2018. “Eating (Or rather, Fasting) Our Way to Rejuvenated Stem Cells?” in Life and Tech @ LifeOmic. June 7. A Medium Corporation.
3. Cadwell K. 2016. “Crosstalk between autophagy and inflammatory signaling pathways: balancing defence and homeostasis.” Nat Rev Immunol.16 (11): 661–75.
4. Menzies FM, Fleming A, Caricasole A, Bento CF, Andrews SP, Ashkenazi A et al. 2017. “Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities.” Neuron. 93 (5):1015–34.
5. Bravo-San Pedro JM, Kroemer G, Galluzzi L. 2017. “Autophagy and Mitophagy in Cardiovascular Disease.” Circ Res. 120((11)):1812–24.
6. Lavallard VJ, Meijer AJ, Codogno P, Gual P. 2012: “Autophagy, signaling and obesity.” Pharmacol Res. 66 (6):513–25.
7. O’Flanagan CH, Smith LA, McDonell SB, Hursting SD. 2017. “When less may be more: calorie restriction and response to cancer therapy.” BMC Med. 15(1):106.

• Roberts MN et al. A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice. Cell Metabolism, September 2017.

A sugar is a monosaccharide if it is made up of a single sugar molecule; it is disaccharide if it is built by two sugar molecules; and a polysaccharide if it is composed with multiple sugar molecules.

Sugars that we ingest are broken, in the digestive system, into monosaccharides of glucose, fructose, and galactose. Almost all of the absorbed monosaccharides are first converted into glucose in the liver. This conversion is a very important task of the liver: 80% of the sugars passing into the blood are glucose. As a result, very limited amounts of fructose and galactose are present in the blood. Therefore, when blood sugar is mentioned, normally glucose is taken into consideration and the fructose and galactose levels in the blood are ignored. Glucose, which is also called grape sugar, is most abundantly found in grapes, while fructose is called fruit sugar, as it is plentiful in fruits, and galactose is named milk sugar after its dense presence in milk. The most important characteristic of fructose is that it is sweeter compared to other simple sugars.

Insulin is secreted from the pancreas in order to lower elevated blood glucose levels after digestion. Insulin functions in the transport of glucose from the blood into cells to provide necessary energy, therefore reducing blood sugar levels; furthermore, it also plays a role in the storage of excess glucose as glycogen, which is found primarily in the liver. Once glycogen storage limits are reached in the liver and muscles, glucose is then stored as fat. Fat tissue acts as sustenance during long fasting periods.

Differences between fructose, glucose, and galactose

Glucose and galactose are absorbed actively, depending on salt. They cannot be absorbed without salt while passing through the intestines. Salt is necessary for the absorption of glucose which is present in the starches of potatoes and other foods. Thus, when potato is consumed with salt, the transport of glucose into the blood is facilitated.

However, salt is not necessary in the case of fructose absorption. The intestinal absorption of fructose contained in fruit is delayed by fruit fibers, since these fibers prevent or balance the transport of fructose into the bloodstream. However, when fructose is ingested as a fruit juice, it is absorbed and joins the bloodstream much faster because of the lower fiber content.

A person feels full after a meal when neurons in the satiety center of the hypothalamus are stimulated by elevated blood glucose. Then, hunger center neurons are repressed, eliminating the feeling of hunger. Therefore, a person reduces their food intake during a meal as their blood glucose levels increase. Increased levels of amino acids and fatty acids in the blood also suppress hunger and stimulate fullness after meal. However, one important point is that fructose does not stimulate fullness in the brain. Therefore, if the blood fructose levels are elevated instead of glucose, a person cannot generate a sensation of fullness sensation. As a result, a person desires to intake more food during consumption of fructose. It is only possible for fructose to generate fullness after it has been converted into glucose by liver.

How to consume fruits?

We should prefer direct consumption of fruits instead of drinking natural or industrial fruit juices because of the high fructose content of fruits. The Prophet Muhammad, peace be upon him, consumed fruits before meals, the wisdom of which we learn only today. Fruits should be consumed at least an hour before or two hours after a meal, for sufficient time should be given for the fructose of an ingested fruit to be absorbed by the intestines and converted to glucose by the liver. Such practices will result in a reduced appetite and food intake. If fruit is consumed after a meal, a delay occurs in the conversion of fructose into glucose since the liver will be occupied by other biochemical processes, along with a full storage of nutrients; this will increase blood fructose levels and fail to reduce appetite. Fatty liver occurs as a consequence of high fat content of the blood. Arteriosclerosis and cirrhosis of the liver may be seen in people with a habit of excessive post-meal fruit consumption.

In a research carried out on laboratory animals, it was found that glucose induces fullness in the hypothalamus and suppresses food intake, whereas fructose was found to repress this effect of glucose, stimulating food intake.¹ Insulin reduces the harms of accumulating sugar in the blood by increasing lipid synthesis. Insulin also takes place in leptin secretion from adipose (fatty) tissue. Leptin is important in the prevention of obesity; therefore, insulin helps in weight loss, too. The leptin hormone causes reduced food intake by stimulating nerve cells in certain parts of the hypothalamus.² Fructose does not cause any leptin secretion because it does not stimulate an insulin release; therefore, it is not effective in generating a sense of fullness.

Ghrelin is a hormone secreted into blood by stomach cells during hunger. This hormone, which produces stomach acids, is enacted through the hypothalamus. It induces hunger, and therefore increases appetite. Insulin secretion increases along with the blood glucose levels during satiety. This eventually causes the increase of the leptin hormone, which also leads to a decrease in ghrelin secretion. As a result, fructose gets absorbed more than glucose in the intestines. Elevated fructose in the blood leads to insufficient or reduced insulin secretion. In this case, a person continues eating.

Fructose and diseases

Free circulation of lipids in the blood damages arteries and veins. For this reason, lipids are transported in “molecular vehicles” that are called as high, low, and very low density lipoproteins (HDL, LDL and VLDL). Neutral lipids (triglycerides) that are present on VLDL (very low density) vehicles are broken down with an enzyme. These lipids are then unloaded from the vehicles by cellular uptake and stored as fats. This transfer of lipids into adipose (fatty) tissue is enhanced via the insulin hormone. In the case of fructose intake, without its insulin secretion effect, lipids accumulate in the blood and liver and eventually prepare ground for liver damage and arteriosclerosis.As the result of a fructose based diet in laboratory animals, it was discovered that lipid production shifted from adipose tissue into the liver, therefore elevating the risk of high blood and liver fat levels.

There are two reasons for this shift. The first one is that fructose acts on the fat producing enzymes of the liver whereas it does not act likewise in adipose tissue.

Secondly, fructose plays an inhibitory role in the conversion of glucose into lipids in adipose tissue. Also, fructose consumption in humans has been linked to elevated blood fat levels.

Overconsumption of fructose causes increased liver fat synthesis. Phosphofructokinase is the limiting enzyme regarding the breakdown of glucose in the liver. This enzyme is regulated by citrates and ATP produced by glucose catabolism and the Krebs cycle, limiting glucose breakdown. However, there is no such limitation in fructose breakdown. Through fructose catabolism, glucose, glycogen, pyruvate, lactate, glycerol and the acyl part of acylglycerol are synthesized. This synthesis can not be limited. As a result of this excessive output and high amounts of triglycerides, VLDL is produced.³ It has been found that persons who consume two or more boxes of fructose sweetened beverages every day carry a 35% higher risk of heart disease.⁴

This isn’t the only disease associated with fructose. In some studies on laboratory animals, it has been reported that a high fructose diet is associated with hypertension.⁵ A lot of research exists suggesting that excessive fructose consumption leads to insulin resistance in both the liver and peripheral tissues, which can often cause diabetes.⁶ In a recent study, it was claimed that excessive fructose intake poses risks for renal diseases leading to glomerular hypertension, renal damage, and inflammation and damage to renal tubules and tissues.⁷

In a study conducted on 21,483 Americans who were older than two years, daily consumption of 37 gr. of fructose (8% of total calorie need) was found to be elevated to 54.7 grams (10.2% of total calorie need) gradually between the years of 1988-1994, mostly consumed by younger people. Increased use of fructose syrup was linked to obesity during the last 35 years.⁸ Furthermore, in a study carried on 1,749 male and female children and teenagers, a positive relation was found between body mass index (BMI) and excessive consumption of carbonated beverages containing high fructose concentrations.⁹ There many studies that support this report.¹⁰ Excessive fructose consumption is known to cause “metabolic syndrome” in which many diseases like obesity, arteriosclerosis, and diabetes emerge together.

Are fruit juices harmful?

Fructose syrup is being used at increasing rates in the food industry. According to the annual report of US Food and Drug Administration (FDA) for the year 2000, fructose syrups are sugar solutions containing approximately more than 50 % fructose. It is often synthesized by a conversion of corn starch into glucose by glucose isomerase.¹¹ There is also a third syrup type containing 90% fructose, however this has limited uses.

The sweetness of fructose syrup is similar to that of table sugar. It prevents the dehydration of food with its hydrophilic character. It is mostly used in aromatic foods, especially carbonated beverages and fruit juices. It prevents the proliferation of microbes with its high osmotic pressure property and makes food more resistant against them. Syrups containing 42 to 55% of fructose are used in baked goods, cereal products, dairy products, processed foods, both carbonated and regular beverages, ice creams, and frozen desserts. High fructose syrups are used in foods to decrease water activity and prevent spoilage.

Fructose syrups have a very low ash level due to application of intense purification processes during production and product color is water-white. Therefore colors of fructose used industrial foods are white as well. Fructose syrups have a lower viscosity and density compared to glucose syrups and therefore it is runny like water and not as sticky.

How to consume sugars after a meal?

Especially after a fatty meal, our body seeks sugar. The reason behind this is the requirement of sugar for the storage of lipids into fat tissue. However, this sugar should absolutely be glucose instead of fructose. Therefore, some amount of sugar can be consumed to facilitate the removal of lipids from blood after meals. This is recommended to lower blood lipid levels. However, this should not be done with fruits but with natural sugars like grape molasses. A baklava or a dessert made with industrial sugars (fructose) will not be beneficial but harmful.

In conclusion, the consumption of corn-derived fructose syrup is gradually increasing in recent years. Fructose syrup is used both in various carbonated or regular soft beverages, and in desserts. The reason for our fructose syrup preference is that it helps preserve foods longer and it leads to food addiction because it enhances appetite due to its strong sweetness. Fructose syrup is synthesized by the conversion of natural glucose in corn into fructose by isomerase enzymes. In this sense, today’s increased consumption of fructose is altering the existing sugar balance of natural food items. Overconsumption of fructose can pave the way to obesity, metabolic syndrome, arteriosclerosis, diabetes, hypertension, and arteriosclerotic heart and kidney diseases.

Arifagaoglu is a professor of medicine in Ankara, Turkey.

References

1. Wolfgang MJ, Cha SH, Sidhaye A. et al. Regulation of hypothalamic malonyl-CoA by central glucose and leptin. Proc Natl Acad Sci USA. 2007; 104: 19285-19290.
2. Guyton AC, Hall JE. “Dietary Balances; Regulation of Feeding; Obesity and Starvation; Vitemans and Minerals.” Textbook of Medical Physiology, Saunders, 2010, 843.
3. Rutledge A, Adeli K. Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms. Nutr Rev. 2007; 65: 13–23.
4. Fung TT, Malik V, Rexrode KM, Manson JE, Willett WC, Hu FB. Sweetened beverage consumption and risk of coronary heart disease in women. Am J Clin Nutr. 2009;89:1037–42.
5. Barone BB, Wang NY, Bacher AC, Stewart KJ. Decreased exercise blood pressure in older adults after exercise training: contributions of increased fitness and decreased fatness. Br J Sports Med. 2009;43:52–6.
6. Blakely SR, Hallfrisch J, Reiser S, Prather ES. Long-term effects of moderate fructose feeding on glucose tolerance parameters in rats. J Nutr. 1981;111:307–314.
7. Johnson RJ, Sanchez-Lozada LG, Nakagawa T. The effect of fructose on renal biology and disease. J Am Soc Nephrol. 2010; 21(12): 2036-9.
8. Bray G. Fructose: should we worry? Int J Obes 2008;32: S127-131.
9. Forshee RA, Storey ML. Total beverage consumption and beverage choices among children and adolescents. Int J Food Sci Nutr. 2003; 54: 297–307.
10. Forshee RA, Anderson PA, Storey ML. The role of beverage consumption, physical activity, sedentary behavior, and demographics on body mass index of adolescents. Int J Food Sci Nutr. 2004; 55: 463-478.
11. Melanson KJ, Angelopoulos TJ, Nguyen V, Zukley L, Lowndes J, Rippe JM. High-fructose corn syrup, energy intake, and appetite regulation. Am J Clin Nutr. 2008; 88(6):1738S-1744S.

Humps store fat and also protect camels’ other tissues from heating due to sun light. It has also been reported that camels’ coats insulate them from heat by reflecting sunlight. This extra fat tissue (about 10-15 kg) provides not only energy in long desert journeys but also water through a biochemical process which leads to the production water molecules (1,111 g of water per 1,000 g of fat converted). It is also noteworthy that sparing a specific part of the body for storing fat and refraining from storage in other tissues provides decreased fat density, thus lessening heat retention due to fat.

Water is scarce in the desert and needs to be stored in large amounts when available. Amazingly, camels can drink up to 150-200 liters of water at once, and yet, after three days, there is no sign of water in their stomachs. Drinking so much water in such a short time could be a problem; this would be like a human drinking 20-40 liters of water in 10 minutes, which would induce water intoxication. The oval shape of camel’s red blood cells, and their ability to swell until double in volume provides plasticity in this situation.

Camels can lose up to 25% of their bodily fluids without showing signs of dehydration. This provides an extra durability against long-term water shortage. For comparison, most mammals can only withstand about 3-4% dehydration; further water loss might lead to cardiac failure due to thickened blood. Another protective property given to camels that allows decreased water loss is that they drop feces that are so dry they can be used as a fuel. For comparison, a dromedary camel loses 2.5 liters of water daily through feces (about just 40-60% water) while cattle lose 20-40 liters.

Camels also regulate sweating in a unique way. Their body temperature does not need to be constant; it can move between 34 and 41 degrees centigrade. They don’t sweat until it is over 40 degrees. These regulations allow them to preserve approximately 5 liters of water per day. A camel’s kidney function is also tightly regulated according to the availability of water. If they don’t drink water for days, urine production is limited to approximately 500g. On the other hand, if water is abundant it could go up to 7 liters. This urine is unusually thick, too – it resembles syrup. Remarkably, camels never run, which would increase transpiration; instead they just amble quickly.

However, dehydration can be still an issue, which will negatively affect the flow of red blood cells. Remarkably, camels have oval red blood cells, which better resist clumping when compared to round, human red blood cells. There are no other mammals with oval red blood cells.

Food is another problem for animals living in the desert, especially for big ones like camels. Interestingly, camels have split lips, which allow them to graze easily. They can eat thorny twigs without any injury. Eating green plants also provide the moisture that they need.

Sand is often a problem, especially during sand storms. Remarkably, camels are equipped with systems that allow them to close theirs nostrils to get protection against wind and sand. In addition, camels have two layers of thick eyelashes, which provide additional protection from the dust. The specific shape of their nostrils allows them to preserve vapor and allows returning it to the body.

Traveling over sand is difficult. Camels are created in a way that allows their four legs to kick in all directions. Remarkably, Camels are equipped with paddy hoofs and two toes to protect them from sinking in the sand and burning of the hot sand. In addition, they have long legs, which keep them further from the hot ground.

Though the modern world seems to have replaced them as a major mode of transportation, they are still widely used in areas such as North Africa.

It seems likely many more remarkable discoveries about camels are on the horizon. Medical researchers are studying how camels function – because these amazing animals might contain a secret which could save human lives.

Link between excess body fat and cancer

It is obvious that camels undergo a rapid cycle of fat storage and destruction. They store large amounts of fat – up to 15 kg. The correlation between excess body fat and various cancers in humans has long been known. For instance, a WCRF report recommended maintaining a BMI of 20-25%, and claimed it as one of the key factors can prevent cancer. However, a connection between obesity and cancer at the molecular level remains largely unknown. Intriguingly, a recent study performed at UT Southwestern Medical Center by Dr. Scherer and his colleagues shows how fat cells induce cancer cells to thrive in the breast, or fatty livers.

They showed that fat cells allow the growth of tumors via the secretion of a variety of extracellular factors. One of the fat cells derived extracellular factor, which is found abundantly in unhealthy fat tissue, is endotrophin. What endotrophin does is cause induction of blood vessels, which feeds tumors; as we gain weight, this increases the chance of getting cancer. The inhibition of endotrophin by antibodies in mice with breast cancer had a remarkable reduction on tumor growth and prevented metastasis to other tissues.

Well, if fat is bad and could increase the chance of cancer, and camels store and destroy fat as a survival mechanism, then how do camels manage the increased risk of cancer? Do they also have another remarkable property that lies on the horizon to be discovered? It’s probable there is a mechanism in camels that protects them from such adverse effects of excess fat. If so, how can we benefit from it to solve one of the biggest hurdles to human health? Some researchers might be close to answering these questions.

Antineoplastons

An interesting study, started back in 1967 by Dr. Burzynski and colleagues, examined the peptides in the urine samples of healthy and cancerous patients. They have found that cancer patients lacked a significant content of peptides in their urine. This finding led to the hypothesis that there might be a protective mechanism against the formation of cancer in the body through peptides. They identified a specific group of peptides found in the urine, later named Antineoplastons that show anti-cancer properties. A treatment scheme was developed through balancing the antineoplaston deficiency in cancer patients to control the abnormal cellular growth. They have tested both in laboratory and on the various cancer patients, and demonstrated some degree of response, albeit with excessive criticism from the scientific community. The mechanism of action of antineoplaston is proposed as functioning as a molecular switch; this activates tumor suppressors and inactivates oncogenes (drivers of cancer formation). Dr. Burzynski, in his clinic at Houston, TX, is still providing treatments to cancer patients with late stages of cancer using Antineoplastons, and claiming that there are survivals with his approach.

The use of compounds identified in the urine could be considered as a kind of urine therapy, which is used as an alternative treatment to cancer that has been historically practiced for different purposes. This reminds me of the prescription of some Bedouins, who got sick when they came to city. They suggested drinking the milk and urine of freely grazing camels at the city’s outskirts. It has been said that they drank this concoction and grew healthy again. This incidence and historical use of urine therapy suggests that camel’s milk and urine could have unique substances that might be effective in the treatment of diseases, maybe even of cancer. An interesting point here is that the Prophet Muhammad, peace be upon him, specifically ordered to drink from animals that are freely gazing, which is also mentioned in the Qur’an, such as in the miracle of the Prophet Salih with the she-camel about which his community was tried: “[S]o leave her to feed in God’s earth” (11:64). This points to not only the consumption of products from freely grazing animals, which is known to affect their nutrition levels and taste, but also to their increased therapeutic potential.

The Holy Qur’an calls for reflection on the camel specifically. I am little bit disappointed that the Houston Zoo does not have such a monumental animal. Contemplation on the camel provides various lessons on the understanding the Maker and Owner of the worlds and living beings, and the superior techniques used in the makeup of animals that live in the harsh conditions of deserts.

References

• 10 Amazing Facts About Camels. Retrieved from http://news.softpedia.com/news/10-Amazing-Facts-About-Camels-68843.shtml on April, 14, 2013.

• 20 Amazing Facts About Camels. Retrieved from http://www.environmentalgraffiti.com/news-expressive-faces-camels?image=1#mzJyLiKcQPMoM1tD.99 on April, 14, 2013.

• Facts About Camels. Retrieved from http://lifestyle.iloveindia.com/lounge/facts-about-camels-1654.html on April, 14, 2013.

• Camel. Retrieved from http://en.wikipedia.org/wiki/Camel on April, 14, 2013.

• Excess Body Fat Causes Cancer. • The WCRF report, 2007. Retrieved from http://www.medicalnewstoday.com/releases/87350.php on April, 21, 2013.

• Finding – and fighting – the fat that fuels cancer. Retrieved from http://www.utsouthwestern.edu/newsroom/news-releases/year-2013/feb/endotrophin-scherer.html on April, 21, 2013.

• Jiyoung Park and Philipp E. Scherer. Adipocyte-derived endotrophin promotes malignant tumor progression. J Clin Invest. 2012;122(11):4243–4256. doi:10.1172/JCI63930.

• Stanislaw R. Burzynski. The present state of antineoplaston research. Integr Cancer Ther. 2004 Mar;3(1):47-58.

• Urine Therapy. Retrieved from http://en.wikipedia.org/wiki/Urine_therapy on April 22, 2013.

• Ravi: Enes. Tirmizi, Tibb 6, (2043)

Imagine: I have just been cooked, and I am now waiting on a dish. Oh, what’s that? A metal thing with four prongs has just stuck itself into my chest, and it threw me into a shaking room with a gate moving up and down. There are, in this room, 32 flat and occluding rocks, some of which are sharp, while some are like millstones, all being lined up in a U-shape row. The frontal rocks have divided me into large pieces by squeezing and cutting. My pieces are pushed backwards by a soft shovel underneath. The rear rocks have made me almost like a paste, thoroughly mashing my pieces. Meanwhile, many taps on the right and left sides and in bottom of the room began flushing water upon me, and the carbohydrates within me have began dissolving by the pityalin enzyme (alpha amilaz) in this water. The flushing water contains substances such as lyzozym and antichore to eliminate any probable microbes within me.

I was fully softened and turned into something almost like gruel, when suddenly I was impelled by the actions of that soft shovel to an extremely tight tube inside of which movements continuously push me downward. A gate opened while I was being brought down and, as I was hoping to enter into a more spacious room and be saved from the compressive movements, I suddenly flopped into a well containing a light-colored liquid. I have come to know, while I was expecting to have some refreshment, that the liquid I flopped into was an acid capable of eroding marble (pH=0,8). I cried ‘Oh My God!’, but it was too late. This acid began to break my proteins down. The pepsinogen which was simultaneously being secreted by some cells over the walls of this large room and which were ineffective within an acid-free environment, became instantly activated by this acid and began to thoroughly break me up. Most of my proteins were broken. While I was wondering and asking ‘how come the liquid I flopped into is capable of eroding the marble but not capable of breaking up this well?’, I have come to notice that walls of the well were coated with a thin layer of mucous substance (membrane) which is unbreakable by acids.

I said ‘Oh My God! As long as you do not permit, these acids, which can erod marble, are not capable of damaging a soft tissue!’. Together with other foodstuff, I have been both blended and broken in this well-like room for about an hour. Later, the outer walls have again squeezed us, and we have been ejected yet again, this time into a new tube at an opposite direction to the one we were just pushed out of, by a sudden loosening and opening of a valve. This tube (called duodenum in Latin) has a length of about 15-18 cm and, appears as if lined up side by side. Here too, we felt wretched and were faced by a basic secretion (sodium bicarbonate) being ejaculated from a tap. This liquid was inactivating (neutralizing) the acids mixed with us, i.e., preventing them from damaging the unprotected walls of the tube which we were in.

Here again the amylaz, lipaz, trypsin, kymotrypsin and carbocsypolypeptidas attacked me, all of which break up, in a respective order, carbohydrates, fats and proteins of my ingredients, along with a lot many other enzymes, and they broke me up to my smallest constituents. Meanwhile, I started pondering the reasons why these enzymes, which are making mincemeat of me, are not damaging the tap (pancreas), which are composed of the same proteins, fats and carbohydrates that they come from. Then, I have come to realize that these enzymes could not become activated in pancreas tissue, since it does not have any activating factors, but they gained shredder features only after we arrived in the tube we are in, and only with the help of such factors which are being secreted from the intestinal walls.

After having been fully shredded within this narrow tube, a green liquid (bile), was poured on us as we were approaching its end. This detergent-like liquid was particularly responsible for shredding the fats in my ingredients. I understood, after all of this, that I was passing through a very excellent factory. As I and my fellow meatballs proceeded inside this narrow tube of approximately three meters long, no part of us remained un-shredded, except the cellulose fibers of plants such as parsley and onion which accompanied us. They continued their journey until arriving at a very thick and short tube. I have found out that their sap have been absorbed and their leftovers, after being amassed for some time, have been thrown into a cesspool called a toilet.

In the meantime, we have noticed that the walls of this tube are plicate and protuberant. These walls are apparently the places where our particles penetrate into another realm through two different ways. We understood that, via rather thin capillary channels situated inside these protuberances, we were being transferred into narrower tubes which contained two different (red and white) types of liquids (blood and lymph vessels). Now, there isn’t ‘me’ anymore, instead, there is only an ‘us’ which is composed of very smaller particles. While glucoses, the simplest forms of carbohydrates and aminoacids, the simplest forms of proteins are being transferred into the red liquid, our fat acid siblings are transferred into the white liquid of lymph vessels. Our glucose and aminoacid siblings have been carried by the red liquid to a factory called a liver. They are being returned to the red liquid after having passed through certain processes and being equipped with some useful characteristics here. But, the fats (lymphs) of the white liquid are, for some reason or another, being separately transferred into the red liquid, bypassing this factory. I learned the reason later: if the fat acids came to the liver together with glucoses and aminoacids, they would spoil this factory and kill its workers.

Finally, the red liquid carried us to tiny cell chambers numbering almost 100 trillion. Each of our tiny particles were sent to separate cells. Here, water, carbondioxide and energy were being produced by primarily coupling of our sibling glucose with oxygen. I learned that energy was needed for the functioning of these cells. Our fat siblings were also being utilized (consumed) for producing energy if glucoses were found insufficient for that purpose. Our amino acid siblings were being utilized (consumed) in the production of sound (strong) proteins and glucoses, and of energy in cases of the unavailability of fat sources for use in the cells’ structures. Excessive amounts of fat and glucose were being stored in these tiny cells. That is to say, I, who was a meatball at the beginning, was converted into water, carbondioxide and energy at the end of this painstaking journey. I was promoted (exalted) to the degree of humanness and rewarded a great deal of honor, as some parts of me became constituent of and some other parts of me assumed responsibility in vital cell functions of the human body.

After all these disintegrations and absorptions, some parts of us took their share in the structure of the body, while some others which were used in energy production including me were converted into a choky and dirty gaseous state called carbondioxide. We have been thrown back into the red liquid again since we would perhaps choke the cells we are within should our density increase very much. We have been brought to a marvellous and sponge-like factory named a lung, and composed of millions of vesicles, by being placed onto a molecule called hemoglobin, which is being pushed by a big pump. We have replaced the oxygen of the fresh air arriving to the lung vesicles. Now is the time for bidding farewell the human body. I thanked God, for I regained my freedom as a carbondioxide passing through and escaping from very dark and narrow places.

However, I was placed upon the leaf of a green plant after aimlessly roaming in the air for some time. After being filtered through the little windows (stoma) over the leaf, I was brought inside by the chlorophyll factory marvelously functioning inside these cells. Here, they forced me to unite with the water brought by tubules from the soil. Upon telling them that I cannot afford to do that, they instantly changed my true nature with solar rays and turned met into a chemical energy depot. I was no more a simple carbon atom; thus, I found a place for myself within an energy-emiting glucose molecule. I was in a position suitably convertible to starch, protein or fats in accordance with the true nature and genetic program of the plant I was within. Something incredible happened while I was swinging around on a green clover leaf. The leaf I was in has been eaten by a cow with real pleasure.

A new chapter has now opened inside the cow’s body. I was assigned with certain duties within the muscle proteins of my new host after having passed through a number of chemical processes. And I really enjoyed them. I was feeling myself more as an animal protein than a simple grass. By leaving the grass for a cow’s body, I was promoted (exalted) one more degree on the way to becoming manifestations of the divine attributes of God.

This blessed animal in whom I was assigned has been sacrificed during a Muslim feast of sacrifice, its meat ground into a meat grinder, and I have been served to you once again as a meatball.

Ali Uguz is a teacher of biology. He lives in Turkey.

The skin, which covers a total surface area of approximately 1.65 m2 and which weighs in total about 9.5 kg, is surely the largest and the heaviest organ of the human body; yet its miraculous functions are still a puzzle to us.

A layered structure

The human skin is composed of three layers: the epidermis (outermost layer), the dermis (vascular connective tissue below the epidermis) and the hypodermis (the deepest portion of the skin), each of which has a very complex metabolism of its own. Each of the structures of which the skin is comprised has a wide variety of functions; all of these functions must be in order if we are to maintain our good health. In particular the epidermis and the dermis each have their own distinct functions, but also share some duties, and all of these are essential for the survival of the human. The thickness of the skin varies from 8 mm on the palms and soles of the feet to nearly less than 1 mm on the eyelids. Within the epidermis are found four dif¬ferent types of cells that undertake different tasks; the appearance of our skin, in terms of texture, evenness of color, hydration, and overall youthfulness and constitutional health, is greatly dependent on the interaction of these cellular functions.

A single organ with several functions

It is very interesting that the majority of people are not aware of the fact that the skin is one organ.

Not only does it cover the body, our skin performs many amazing tasks such as,

-helping with water conservation,

-helping with the maintenance of body temperature,

-perception of touch

-providing a barrier to harmful germs,

-storing fat,

-storing vitamin D,

-acting as a mechanical barrier against knocks or bumps,

-helping in the removal of the waste products of metabolism

-providing protection against environmental influences, such as cold or high temperatures, and destructive ultraviolet rays, as well.

It is common knowledge that the major task of our skin is to protect the human body from harmful environmental factors. It is, indisputable that the fundamental purpose of the skin is to provide a flexible, protective shield between us and the outside world. This is made possible by the layers of flattened epithelial cells which hinder micro-organisms and chemicals from entering the body.

Constant replacement

The benefits we have mentioned would not last long, however, if skin cells were not renewed. This amazing regeneration process happens through a replacement operation that is dependent on a continuous cell division in the basal layer. As the cells move towards the outer surface they lose their softness. Consequently, they gradually die off and stiffen. Dead cells are constantly sloughed off from the upper surface of the epidermis and are continuously shed; they are replaced by new cells that are generated in the deeper layers. This process is often referred to as “cellular renewal.” As cells progress through the various stages, they finally stiffen and die or keratinize. This dead cell layer, or keratinocytes, makes up the outermost layer of the epidermis, the stratum corneum. These hardened and cornified cells are designed by our Creator to act as a protective barrier; otherwise, living cells would not be able to provide the protective qualities necessary to isolate the living tissue from exposure to possible detrimental substances and organisms. The living epidermal cells die by an extremely sophisticated process, displaying a voluntary self-sacrifice that enables humans survive, an evident blessing from our Most Gracious Lord.

Regulation of body temperature

The regulation of temperature is considered to be one of the major duties given to the skin. We naturally lose water through constant evaporation throughout our lives. It is of utmost importance that the loss of too much body fluid is prevented. By narrowing or widening the capillary blood vessels and also by means of numerous sweat glands, evaporation on the surface enables our skin to become cooler or warmer, in a strictly limited range of temperatures. The fat cells of the skin prevent losing too much heat, and when the body overheats, the skin’s extensive small blood vessels carry warm blood to the surface where it is cooled. So, as we can deduce from this, the main task of the skin is to prevent the loss of body fluids through evaporation.

Another task of the skin is the storing of fat and the production of vitamin D [25-dihydroxycholecalciferol]. Vitamin D is a fat-soluble vitamin that is found in food and can also be processed in our body after exposure to ultraviolet (UV) rays from the sun. Sunshine is a significant source of vitamin D because the UV rays from the sun stimulate the synthesis of vitamin D in the skin. This fundamental feature of our skin is, clearly, indispensable to our skeletal development.

The witness

The human skin has also a function in sense communication with the environment. It gathers sensory information from the environment; this is performed by means of a great number of receptors (for example, those for warmth and cold) and intraepithelial nerve endings. Nerve cells in the skin form the body’s first contact with the outer world. At the moment of birth, an infant’s first experiences of the physical world are perceived through the sense of touch. Nerve cells allow the skin to receive and transmit signals from touch, pain, tickling, etc. As the skin is the boundary between a living creature and the world around it, it is also the physical interface between the creature and other creatures and the world. Hence it is the location of all contact, good or bad in kind. The Qur’an declares that the skin will also testify when we are called to account on the Day of Judgment:

Until when they reach it, their ears, and their eyes, and their skins will bear witness against them as to all that they did habitually. They will ask their skins, “Why have you borne witness against us?” They will answer: “God Who makes everything speak has made us speak.” It is He Who has created you in the first instance, and to Him you are being brought back. You did not seek to veil yourselves (when sinning) without ever considering that your ears or your eyes or your skins would one day bear witness against you. (Fussilat 41:21-22)

As pointed out in the verse …the abode of the Hereafter is truly alive (29:64), everything in the Abode of Hereafter will be alive. So, like every part of a human being, the skin will bear witness for or against them. The verse implies that it is the medium where all our contact is recorded and it will be an ideal witness.

Wounds and healing

Another astounding mission of our skin is its role in healing wounds. The human skin has remarkable selfhealing properties, which obviously point to an intelligent design. A skin wound heals from the bottom up and from the edges inward. In the first stages of healing, the basic connective tissue of the skin moves into the injured area. The depth of the wound determines how well it will heal; the regeneration process begins immediately, but we still do not know what the trigger is. As a wound heals, the edges are drawn together by a process called contracture. The most amazing part of this phenomenon are the later stages of healing. It is as if all the cells are fully aware when and where to end the repair. Nobody knows why they abruptly stop working and how they finalize restoration.

A shield against germs

Our skin also serves us by organizing and activating the immune system. Some specific cells, which form a network in the epidermis or in the outer layer of skin, play an important part in this activity, by regulating the immune response to germs. As a major contributor to the body’s immune system, constituting the first line of de fense in keeping out bacteria, viruses, and other organisms that invade the body, the skin is home to enormous quantities of T-lymphocytes, or T-cells. Those domestic defense soldiers attack and destroy bacteria, fungi, viruses, parasites, toxins, and cancerous cells that can cause disease. Thus, the skin is both a watertight barrier surrounding and protecting our body from a number of external assaults, never letting the undesired pathogenic germs penetrate.

Our Almighty and Everlasting Creator has granted us this gift of skin. He knows what those who are in need are in need of, and it is obvious that He is aware of the need of our cells, our organs, and our living metabolism, thus He has given the most favorable structural design to the human body. Just before we pray to Him, we should remember that the more consistent our demands, the more bountiful He will ordain. Frankly, there seems to be no way to explain the miracle of skin other than attributing it to the All- Beneficent God.

References

1. Cognis Deutschland GmbH & Co. KG Skin Care Forum 2006.

2. ABPI – The Association of the British Pharmaceutical Industry.

3. Dr. K.K. LO, Social Hygiene Handbook – 2nd Edition.

4. Helmut Leonhardt, His, Zyt und Mikroanatomie des Menschen, Vol. 3, Thieme, Stuttgart 1990.

5. H. Brannon M.D., The skin anatomy ed. 2002.

6. Beauty Clinics Hashmi.com. Skin Analysis 2005.

7. Goldsmith LA, Biochem and Physiology of the Skin 2nd ed NY Oxford University Press, 1991. 8. Breathnach AS. Atlas of the Ultrastructure of Human Skin. London: J. & A. Churchill, 1971.

9. Elias PM. Epidermal lipids, membranes, and keratinization. Int J Dermatol 1981; 20: 1-19.

10. National Skin Care Institute 2005-2006 website.

11. Ali Ünal, The Qur’an with Annotated Interpretation in Modern English, The Light, Inc., NJ:2006.

Obesity is harmful to infants as well as adults. Obesity during infancy may, in later life, cause such diseases as arteriosclerosis and the other ailments which often accompany it. Arteriosclerosis in adults is a factor in high blood pressure or hypertension, and in certain diseases of the heart eyes and kidneys. Obesity can also lead to diabetes.

There is a good deal in classical Islamic sources on the subjects of over-eating and obesity. The Qur’anic verses. Eat and drink but not to excess (7.32), and Do not cast yourselves into destruction by your own hands (2.195), may be mentioned (besides their other meanings) as Divine warnings against transgressing the limits in eating and drinking and doing harm to ourselves because of carelessness. All ibn al-Husayn ibn al-Wafid said. God put all medicine into half of one verse [of the Qur’an] when He said: Eat and drink but not to excess.’ The Prophet, upon him be peace and blessings, also drew attention to obesity and over-eating. For example, as recorded by al-Haythami, on seeing a fat man, he said: If you did not have a paunch, it would be better for you. He also said: Overeating does not go with good health. The criterion established by Islam, and reiterated by the Prophet, is: The middle way [avoiding extremes] is the best in every affair.

Among other sayings of the Prophet which warn against the dangers of overeating and obesity are:

Avoid filling the stomach with food and drink. Overeating exhausts the body and causes illnesses. Follow a middle way in eating and drinking as this improves the body. God does not love fat bodies.

The son of Adam [i.e. man] fills no container worse than his stomach. Let him have just a few mouthfuls to strengthen the limbs.

One third of the stomach is for food, one third for drink, and one third for air.¹

The following saying uttered in relation to the spiritual harm caused by over-eating, can also be read in relation to heart diseases arising from overeating:

Do not kill your hearts by eating and drinking too much. For the heart is like a sown field: over-irrigation causes the seed to rot.²

‘Ali, the fourth Caliph, said:

Having suet is a disease. He also said: Fullness causes heart spasms.³

‘Umar, the second Caliph, said: Avoid getting a pot-belly, for it spoils the body, causes diseases, and makes doing the prayer tiring. And avoid all excess, for God hates a learned man who is fat.⁴

Harith ibn Khalada, the physician of the Arabs, was once asked: What is the best medicine? He replied: ‘Necessity- that is, hunger.’ When asked what the disease was, he said:

‘The entry of food upon food.’

lbn Sina, the renowned Muslim physician and philosopher, said: ‘Never have a meal until the one before it has been digested.’ He also advised against excessive salt and fatty meat. His list of food for dieting mostly included vegetables. The prescription is much the same today.

The Prophet, upon him be peace and blessings, also drew attention to obesity and over-eating. For example, as recorded by al-Haythami, on seeing a fat man, he said: If you did not have a paunch, it would be better for you. He also said: Overeating does not go with good health. The criterion established by Islam, and reiterated by the Prophet, is: The middle way [avoiding extremes] is the best in every affair.

The Prophet declared:

Avoid filling the stomach with food and drink. Overeating exhausts the body and causes illnesses. Follow a middle way in eating and drinking as this improves the body. God does not love fat bodies.
The son of Adam [i.e. man] fills no container worse than his stomach. Let him have just a few mouthfuls to strengthen the limbs.
One third of the stomach is for food, one third for drink, and one third for air.¹
The following saying uttered in relation to the spiritual harm caused by over-eating, can also be read in relation to heart diseases arising from overeating:
Do not kill your hearts by eating and drinking too much. For the heart is like a sown field: over-irrigation causes the seed to rot.

Contrary to some popular superstitions, fat babies are not healthy babies. On the contrary, over-eating is also harmful for children. Children fed on starchy foods without the necessary amount of vitamin D are susceptible to rickets (rachitism). Ibn Sina advised the same nine centuries ago: ‘Avoid giving babies too much food. Over-nutrition of babies causes their urine to be light-coloured’. The fact that a baby goes on suckling does not always mean that the baby is hungry; sometimes suckling is just a reflex action. Dark-coloured urine in babies indicates undernutrition; while a light colour is symptomatic of overnutrition.

Ibn Sina was of the opinion that over-feeding provokes eclampsia (convulsions) in babies. Anther Muslim physician, Abu Bakr al-Razi, also pointed to this link. He said that some infantile convulsions can abate after proper regular nutrition. lbn Sina and al-Razi may have been referring to the kind of eclampsia caused by rickets emerging as a result of obesity: in the syndromes named after Frohlich and Martin-Albright obesity is accompanied by eclampsia.

Ibn Khaldun, a Muslim sociologist and historian famous for his Muqaddima, also mentioned that over-eating causes many diseases. He said: ‘Know that hunger is better for health than eating too much. Even if we cannot remain hungry, eating less is good. Eating less is better for the development of body and mind.’⁵

Other Muslim physicians such as Haji Pasha and Hafiz Hasan Effendi also wrote that giving babies too much milk was harmful for their health. It is now a well-established fact that feeding babies too much milk causes obesity.

Advice on eating and drinking

There are many sayings of the Prophet Muhammad, upon him be peace and blessing, on medicine. They encompass a great variety of subjects including eating and drinking and the mention of certain kinds of food particularly useful for health. In later centuries Muslim scholars collected these sayings, usually under the title of Tibb al-Nabawi. The collections of lbn Qayyim al-Jawziyya, Jalal al-Din al-Suyuti and Abu Nu’aym are among the most famous.

Jalal al-Din al-Suyuti (d.1505), one of the greatest scholars of the Muslim Middle Ages, recommended eating cold foods in summer and hot ones in winter. Hot food should be preferred with cold, sweet with sour, fat with salt and acid with fat. Variety of foods excites the constitution; it is best to eat with relish and enjoyment. Having the same food several times one after the other and eating hurriedly causes loss of appetite and laziness. Eating a second meal without fully digesting the first is harmful. Al-Suyuti also wrote that one should avoid food and drink that has been left uncovered. The Prophet, upon him be peace and blessing, commanded this: Cover your containers and stop up the mouths of your water bottles.

The Prophet disapproved eating food while it is too hot. He never used to blow on his food or drink, or breathe into a container. He also forbade eating lying down.

Taking a walk after eating a meal or doing the prayer is beneficial, specially for the digestive process. The Prophet said: Digest your food with the Name of God and with doing a prayer. And do not go to sleep immediately after eating as this will make you constipated.

The hands should be washed alter as well as before eating. One whose stomach is over-stuffed with food cannot think clearly or wisely. The less a man eats, the less he drinks; and the less he drinks, the less he sleeps; and the less he sleeps, the better he will be in old age. The body of a man over-filled food will be badly nourished, his self will be in a bad state, and his heart will grow hard. Therefore one should avoid too much food as it poisons the heart and slows down the limbs of the body in fulfilling one’s responsibilities toward God. One should also avoid drinking very cold water, for it is harmful to the respiratory system, specially after a hot meal, or after sweet food, or after a hot bath.

The Prophet, upon him be peace and blessing, forbade drinking water at a single gulp. Anas ibn Malik transmitted the tradition that the Prophet used to drink with three pauses and, at each pause, remove his mouth from the container.

Healthy exercise

Moderate exercise is a most effective means of preserving good health. It warms the organs, helps dissolution of waste products, and makes the body light and active. The best time for exercise which does not over-tire the body or make it red. When sweating begins, exercise should be stopped. The type of exercise which increases sweating is not ‘moderate’ but ‘heavy’.

The body’s organs are strengthened and made more vigorous by regular exercise. The same applies to the inner faculties. One who wishes, for example, to improve his memory will improve it by memorizing. There is a specific exercise proper to every organ.

The Prophet, upon him be peace and blessing, advised a form of exercise which is good for our bodies and our hearts when he said: Travel, for you will grow healthy. He also said: Fasting brings health.

Sleep

According to al-Suyuti, the best time to go to sleep is after food has been digested. Over-sleeping is bad for the health; and sleeping face down is forbidden. Sleeping during the hour following sunrise and before sunset is bad for one: it may lead to ailments and indolence. However, a short sleep in the middle of the day is useful for the health and helps one to rise for prayer during the night.

The Prophet, upon him be peace and blessing, used to sleep on his side, facing the qibla (the Ka’ba in Makka). And it is better o go to sleep in a state of wudu.

References

1. The narrations can be found in Tanbih al-Ghafilin by Abu’I Leys al-Samarkandi, (Turkish translation), p. 799, and, lhya Ulum al-Din by Imam Ghazali (Turkish trans.) Vol. 3, p. 186.
2. al-Ghazali, ibid., 3.186.
3. Celal Yildirim, Asrin Kuran Tefsiri, Izmir, :1987, 1.478.
4. Imam Dhahabi, Sifa Demetleri, Istanbul, 21.
5. I. Haldun, Muqaddima (Turkish trans.), Ank. 1977, 1.232.

No religion commends self-indulgence;all religions, and all traditional ways of life inspired by religious principles, commend self-discipline, that is containing and limiting, rather than expanding, one’s needs. Islam, with its conspicuous patterns of regular prayers, fasting and taxation of one’s wealth and property is particularly emphatic about the importance of self-discipline. Within the norms of Islam, self-discipline means a controlled, moderate, balanced way of living – not orgies of self-denial, followed (inevitably enough) by orgies of self-indulgence. Modern Western ways of life are not traditionally based, not inspired by religion, but motivated instead by what the economic market requires, which is for individuals to spend more and more, regardless of need. One area of such spending is food and drink: certainly among the better-off classes in Western societies, food is purchased, partly eaten and partly wasted, on an unimaginable scale. Muslims who are responsive to the Qur’an’s command to avoid squandering and waste, and to avoid activities or habits which cause harm to oneself (as over-indulgence always does), can never feel at ease living according to the modem Western values and norms.

But the reality is that non-Muslims cannot do so either, at any rate not for long, certainly not for ever. Just as over- exploitation and abuse of the environment demands, sooner or later, a return to saner and ethically more sound relationships with the earth’s finite resources, so too overindulgence at the level of individual lives demands, sooner or later, a return to a healthier life-style, a simpler, more sustainable diet. For the present, this reassertion in Western societies of the saner traditional norms (which, as we have noted, are common to all religious traditions) appears in many individual lives as an unpredictable swing between extreme over-indulgence (visible as obesity) and extreme self-denial (seen in crash courses to lose weight). It is true that vast, even obscene, amounts of wealth are engaged in the slimming industry which (as it were) feeds on the inability of many people to achieve a change in life-style and eating habits which they can sustain. Nevertheless, there is a growing understanding that, in the end, fat-free fats are a real waste of energy: the only point in slimming foods and dieting generally is to train oneself to live in a different, healthier way, and do it for good.

What is obesity?

Generally, obesity is regarded as being synonymous with being overweight. This is not strictly accurate. What actually matters is the excess of fat present in the body. One man may be overweight because he sits all day and eats but does no exercise; another, say an athlete, may be overweight because intensive training has increased his muscle bulk. The first man might be called obese, the second could not. However, as it is difficult to measure the amount of fat present in the body but easy to measure weight by simply using scales, the terms overweight and obesity are for everyday purposes interchangeable.

Does obesity matter?

Statistical studies (done by life assurance companies who have to be good at assessing health risk) provide undeniable evidence that obesity increases morbidity (illness) and the likelihood of early death. Fat people are more likely to suffer, among other things, from increased blood pressure (which may be the cause of stroke, kidney disease or coronary thrombosis), diabetes, arthritis, gallstones, varicose veins, complications of pregnancy or labour, and post-operative problems. Other illnesses not necessarily directly caused by obesity may be aggravated by a person being overweight. For example, a man suffering from angina (pain caused by impaired circulation of blood to the heart muscles) is more likely to die suddenly if he is overweight than if he is of normal weight. Obesity matters therefore because it can lead directly to illness (often serious) and reduces lifespan.

Causes of obesity

The one obvious and direct cause of obesity is that food intake is in excess of the body’s energy requirements or, in plain English, overeating. Why do some people eat more than they need?

By far the commonest reason is that their energy use slows down while their food intake remains the same. This happens in many people as they grow older because little by little they slow down physically, whereas their eating habits remain unaltered. This leads to the well-known condition of middle-age spread. Just one potato or one slice of bread more than the body needs each day can add to its weight each week until, perhaps, by the end of the year the excess amounts to a whole stone.

The genetic make-up of some individuals can make it difficult for them to avoid putting on excess weight because their bodies function at a low metabolic rate. Many fat children, though by no means all, probably fall into this category. It is well recognized that fat parents often produce fat children, and it is unlikely that this phenomenon can he explained entirely on environmental grounds as the children adopted by fat parents are no more likely to become fat than other children.

There are people who overeat because they have a psychological or psychiatric disorder of a lasting kind. Others may overeat when they are temporarily depressed or under emotional stress: they look for consolation for their trouble in eating. For example, some cigarette smokers when trying to give up their bad habit try to compensate by eating. It has also been suggested that, after giving up smoking, the bowel tends to absorb food more efficiently which may aggravate the problem of increased weight.

According to a theory that has been popular for some years now children who are allowed to become fat during the first two years of their lives form a large number of fat cells. They then spend the rest of their lives filling up these cells with fat that is, they have an increased predisposition towards depositing fat within their bodies. However, though popular, this theory has not yet been proved.

Cultural norms and expectations influence people in all sorts of ways, among them, in the way they look. In most Western societies of the present, the cultural preference is for slimness. But this is not true of all societies, not even all Western ones – for example, in southern Italy and elsewhere in Europe, a mother is expected to be ‘well-rounded’.

Treatment of obesity

Treatment of obesity requires a reduction of calorie intake to below the level of the body’s daily energy requirements. Weight will he lost only if there is a negative calorie balance. Eating less food than the body requires means that the body uses up its own fat to meet its energy requirements. In extreme cases, where losing weight is of paramount importance and where, for one reason or another (usually psychological), dieting has failed, surgical procedures may be necessary. These can include wiring up the jaws to prevent entry of solid food while allowing liquid matter to enter the mouth, or even more rarely, short-circuiting large sections of the bowel, a high risk procedure that carries with it a very significant mortality rate.

Nutrition and diet

Nutrition is concerned with the correct provision of essential factors for body growth, maintenance and repair, together with the necessary number of calories to meet the body’s energy requirements. A correct slimming diet is one that reduces the daily intake of calories without depriving the body of its nutritional needs. Some understanding of nutrition and correct dieting is important not only for those who are already obese, but for many young, normal individuals who, without this knowledge would be likely in the course of time to become obese. A well-balanced diet must have adequate amounts of proteins, carbohydrates, fats, vitamins, minerals, mineral salts and water. Proteins, fats and, particularly, carbohydrates, are important sources of calories and hence of energy. Proteins also supply the amino acids essential to body growth and repair. Fat in addition to being a subsidiary source of energy is the principal source of some vitamins.Vitamins are important in the utilization of energy and in the body metabolism but are not themselves a source of energy and do not contribute to body weight. Lack of vitamins causes disease but so too can an excessive intake of some vitamins. 

A number of mineral salts are essential for the human body. Iron, for example, is essential for the formation of hemoglobin. Calcium is necessary for ossification of bone (the change of cartilage into bones). Phosphorus is required for many purposes including the manufacture of ATP. Iodine is necessary for the correct functioning of the thyroid gland. Other important minerals include potassium and sodium.

Water is one of the most important elements in our diet. It makes up about 70% of body weight and shortfall in its intake results in dehydration. Caloric foods are essential for body energy requirements. To appreciate their importance it is necessary to understand both how calories are expended by the body and how these calories are provided by the food eaten. The total calories expended by the body each day is the sum of the calories required for basal metabolism and those required for physical activities. Basal metabolism is the chemical change occurring within the body in the state of complete physical rest when the only bodily functions that are occurring are respiration, growth and repair of body tissues. Physical activity includes obvious exercise such as walking or running and other activities such as digestion and absorption of food. The requirements of basal metabolism depend on the size of the person, but on average about 1,700 calories per day. For comparison it is interesting to note that walking utilizes about 200 calories per hour, household work about 100 calories per hour, and mental work no calories.

Calories are provided by certain constituents of the diet. The most prolific source on a calorie-per- weight basis are fats, which yield 9 calories per gram, followed by carbohydrates and proteins which each yield 4 calories per gram. It would appear that, in order to lose weight with maximum efficiency, the part of the diet which should be reduced is the fat content. However, the average diet contains nearly twice as much carbohydrate as it does protein and fat put together. Therefore, in practical terms, most slimming diets concentrate on the reduction of the carbohydrate content of the food eaten.

Dieting

By ‘dieting’ people usually mean a ‘reducing diet’, that is, a programme of eating less in order to achieve weight reduction. But there are other types of diets used for different purposes such as lowering the level of cholesterol or increasing the bulk content of food in the bowel.

Reducing diets are designed to provide less calories in the food intake than are used by the body in the expenditure of energy. There are infinite variations, both in the content of such diets and in their efficacy.At its simplest, good diets are diets that work. The important criteria of such diets are:

1. Palatability: it is pointless following a diet which forbids all foods that one likes and allows only foods that one dislikes.
2. Practicability: that is a diet that can be followed with a minimum of fuss and preparation and can be used when one is out at work or at a restaurant.
3. Moderation: a diet should be one that ensures a weight loss of not more than 2 lb a week. Diets which produce weight loss in excess of 2 lb are usually crash diets and come into the second category namely, bad diets.

Bad diets fail to satisfy the criteria described above. They fail because they are monotonous or cause tremendous hunger and are soon abandoned, with a consequent return to previous eating habits and the regaining of weight lost. Even if maintained with perseverance and weight is successfully lost, when the diet is eventually stopped, when the desired weight has been achieved, former eating habits are almost always resumed and weight rapidly regained. Weight rapidly lost is weight rapidly regained in almost every instance. It hardly needs saying that the most important aspect of dieting is the re-training of one’s eating habits so that after a time dieting is no longer a conscious activity but a totally natural and permanent way of eating for health. In practical terms the most effective way of achieving this is by gentle reduction of the amount of food eaten. For example, one potato less, one slice of bread less, substitution of artificial sweeteners instead of sugar, are all ways of reducing calorie intake in a gentle and painless manner. There are numerous other tactics (usually classed as behaviour therapy) such as eating from a smaller plate, which can all help different individuals to adapt gradually and permanently to a different regime of eating.

Slimming tablets are controversial. Opinion as to their usefulness is divided. They appear to be very popular with patients but not so popular with doctors. It is possible that tablets have a use particularly when hunger is a problem during sensible dieting or when the reduction of weight has reached a plateau which appears to be permanent or long-lasting. A short-term plateau is a common occurrence while on a reducing diet and perseverance is required as weight loss is usually resumed after a short period. The problem with slimming tablets is that they can cause unpleasant side effects such as insomnia or, conversely, drowsiness, and they may cause dependency. 

Exercise

The importance of exercise in the context of weight reduction is frequently overstated. For example, a walk of one mile will probably use up less than 60 calories. If this activity is undertaken every day it will probably achieve a weight loss of less than 1 lb a month. However studies have shown that sedentary individuals appear to lose weight with more difficulty than active individuals on identical diets.

Bran

Recently doctors have become aware of the importance of something that has been missing in the refined diets of Western societies for a long time: this is vegetable fibre. Observation of peoples in the African continent have shown that the local inhabitants rarely suffer from constipation, bile and other bowel disorders so common in Western countries. This has been convincingly explained as being due to the presence in their diet of vegetable fibre. The theory has been advanced that if vegetable fibre is added to our Western diet the incidence of such bowel disorders will be reduced and this appears to be borne out. The addition of vegetable fibre, generally in the form of bran, may well prove to be a useful constituent of our everyday diet. A further advantage of bran, particularly while on a reducing diet is that it has a tendency to fill up one’s stomach and thus alleviate hunger.

Diet and corona heart dease

Cholesterol is a fatty substance present in everyone’s blood. It causes problems as it is deposited in the lining of arteries making them narrower. Cholesterol also forms an important constituent of arteromatous plaques (lumpy deposits on the inner lining surface of arteries) which may cause narrowing or blockage of the coronary arteries (those supplying the heart), leading to pain on exertion (angina pectoris). Blockage of the coronary arteries causes coronary thrombosis which results in destruction of the heart muscles. The relationship between high blood cholesterol levels and coronary heart disease is undisputed. Numerous studies have shown that the risk of dying from coronary heart disease is more than doubled if one has an abnormally high level of cholesterol in the blood. The relationship between blood cholesterol levels and coronary heart disease is probably a direct causal one. The classic observation is that Japanese men who came to live in San Francisco acquire high blood cholesterol levels and suffer an increased incidence of coronary heart disease in similar proportions to those of the indigenous population and in marked contrast to the low cholesterol levels and low incidence of heart disease of the indigenous population of Japan. However, the possibility remains that some other factor or factors are responsible for both the high cholesterol level and coronary heart disease has been postulated.

Cholesterol is derived partly from the diet and partly from the breakdown of other food substances within the body. The main sources of cholesterol are animal fats and dairy products. These include fatty meats, liver, milk, cheese, cream and butter. All these foods contain a good deal of saturated fatty acid which in the body breaks down to form cholesterol. In addition, eggs contain pure cholesterol. When the amount of cholesterol and saturated fatty acids in the diet is reduced the level of blood cholesterol is also reduced.

What does seem likely is that even a moderately raised level of cholesterol over a long period of time may predispose towards coronary heart disease. Doctors and nutritionists are therefore becoming increasingly aware of the importance of correct diet starting in childhood. It is likely (and certainly it is to be hoped) that, with increased general awareness of the importance of cholesterol levels, there will be some alteration of the present eating habits in schools – informed teachers could provide an important impetus. This is particularly desirable as the eating habits of adults and their likes and dislikes are acquired largely during childhood. There should be a trend towards a reduction of the animal fat and dairy product content of the diet (though by no means their total exclusion because they still form an important source of certain essential nutrients) together with an increase in food containing more polyunsaturated fats (which do not lead to the rise in cholesterol levels) such as lean meat and the substitution of soft margarine high in polyunsaturated fats in place of butter, and the use of corn oil, sunflower oil and safflower oil in cooking instead of cooking fat.

As Muslims, of course, we must be abstemious and refrain from overindulgence. Good health is a valuable gift from God Almighty and we shall he held accountable for how we treated our bodies. In the inimitable words of the Wise Qur’an: Let not your own hands contribute to your own destruction’.