Fear of obesity may sometimes lead people to an extreme diet, and this may cause a deadly disease: anorexia nervosa. The sufferer initially tries to lose weight by going on a diet, but the illness soon reaches the point of no return as the result of extreme dieting. At this point, weight loss cannot be stopped; the person can no longer eat, even if he or she may want to. If they do manage to eat a little food, they throw it up. This disease and many other health conditions are connected with how our bodily functions like appetite are regulated with the secretions in our brain.

Discovered in 1998, orexin is a neuropeptide, or protein-like substance secreted by the brain. It is responsible for regulating states like wakefulness, appetite, and arousal. There are tens of thousands of neurons in the lateral hypothalamus of the human brain that secrete orexin. It was first discovered to increase appetite, but later other functions – especially in relation internal organs – were identified, including regulating the body’s energy use.

Orexins play very important roles in the development and maturation of the brown adipose tissue, which is especially important for infants. The fats in this tissue are directly converted into heat. It is the duty of the adipose tissue to protect the body from illnesses in cold weather. Experiments on lab rats have revealed that body temperature decreases in animals without orexin in their body, and they fail to consume fats. The conclusion is that orexins help boost energy consumption, protect the body from cold-related illnesses by raising the body temperature, and prevent obesity.

Orexins also help regulate metabolic activity and its speed. They are also responsible for regulating the circadian rhythm, or the daily sleep-wake cycle, especially by helping us stay awake. Orexins help increase the secretion of dopamine, norepinephrin, histamine, and acetylcholine hormones, which are in charge of the proper functioning of the daily sleep-wake cycle. All these hormones are substances that increase wakefulness.

The destruction of neurons responsible for producing orexin leads to a severe illness called narcolepsy, which is a serious sleep disorder. Patients suffer from sudden fits of involuntary and extreme sleepiness, irregular nighttime sleep, sleep apnea, various hallucinations, and muscular paralysis called cataplexy. They may suddenly fall into REM asleep while driving and watching television. The muscular paralysis accompanied by REM sleep makes sufferers collapse wherever they may be. They sometimes cannot move and remain motionless, even when they wake up. The fits of sleep strike with or without forewarning and make the need for sleep impossible to fight off. Since frequent uncontrollable collapses may cause injury, narcoleptics know they have to take precautions when they perform daily tasks. Generally appearing in a person’s twenties, the disorder may result from organic factors such as inflammation or a tumor in the brain or other underlying hostile causes.

Narcolepsy is untreatable. It can sever patients from real life and incapacitate them, leaving them unable to perform routine daily tasks. Treatments that are available can only make patients’ lives bearable.

Cataplexy is a condition in which muscles become dysfunctional, speech becomes incomprehensible, and the body collapses due to loss of strength in the neck or knees. Fits may also appear in the form of emotional responses such as excessive laughter, anger, or fear. The duration of cataplexy may last from a few seconds to a few minutes. Patients do not become unconscious during the attack; they just lose control of their physical functions. More often than not, people who have a cataplexy attack in public places seem to be under the influence of alcohol or drugs. They can see and hear others, but they cannot respond.

Sleep paralysis is a temporary state of inability to speak or move during sleep. Although it may look frightening, it is in fact not dangerous. Hypnotic hallucinations, on the other hand, are extremely vivid and frightening dream-like states experienced when falling asleep or waking. An extreme tendency for daytime sleep and hypnotic hallucinations are consequences suffered by people who have not had enough sleep, whereas cataplexy is unique to narcoleptic patients.

Orexins are also responsible for increasing the amount of nutrition a body consumes. This duty is not about meeting the body’s daily diet. Orexins tend to increase appetite, even when the body does not need feeding. They suppress the feeling of satiety, causing the person to continue eating. The willpower should kick in at this point, and the person should use it to stop eating.

The secretion of orexin is influenced by two opposite hormones. The first is leptin, secreted in obese people. Leptin’s duty is to prevent the person from overeating by reducing orexin secretion. The second is ghrelin, a digestive hormone secreted when the stomach is empty. Ghrelin increases orexin secretion, causing an increase in appetite.

It has also been discovered that orexins are connected with smoking and drug addiction. Medicines that reduce orexin secretion are used in addiction treatment. Orexins stimulate the neurons of pleasure in the brain, the reward centers, and impact a person’s happiness or sadness. A reduction in orexin secretion leads to unhappiness and sadness.

References

• Herring W. J. et al. “Orexin receptor antagonists for the treatment of insomnia and potential treatment of other neuropsychiatric indications”, J Sleep Res., 2018; e12782. doi.org/10.1111/jsr.12782.
• Kaushik, M. K. et al. “Continuous intrathecal orexin delivery inhibits cataplexy in a murine model of narcolepsy”, PNAS, June 5, 2018 115 (23) 6046–605.
• Zhou, W. et al. “Activation of orexin system facilitates anesthesia emergence and pain control”, PNAS, November 6, 2018 115 (45) E10740–E10747.

Are cities the same as water? It’s possible to look at chemistry for new understandings of social dynamics.

The universe is a field where existence is transformed from state to state. The transformation of matter from one state to another is generally called a “phase transition” and each phase has its own characteristics. A phase transition is possible via the alteration of some parameters and variables. For instance, heat is one of the parameters required for the transition of ice (solid) into water (liquid) and later into vapor (gas); the increased heat causes ice to change states. The characteristic feature of each phase (ice, water, and vapor) is unique. For example, ice has a certain volume; however water and vapor take the shapes of their containers. In contrast to ice, water and vapor have flowing properties.

In a similar way, if the temperature of a ferromagnetic material displaying magnetic properties is elevated, at a certain temperature, it is observed to lose its magnetism; this is called the “Curie point.” In some materials, such as some solutions, the transition into different phases can be achieved by adding solvents.

Seasons can also be considered different phases. Each season has its own specific traits and features. Seasons are generated by the alteration of the angle between the axis of earth and its orbital plane.

As these examples show, the universe resembles an erase board where continuous transitions are taking place, new sentences are being written, and existing writings are dismissed to form new sentences with new meanings.

In a recently completed academic study, a new definition of a phase transition encountered in social life has been made and this phase transition is called “freezing by heating” [1]. It is well known in daily life that the less individuals are informed about their temper and the direction they are headed, the weaker the efficiency of cooperation among individuals. If people in a unit or group behave irregularly, a dead end or bottleneck could occur. Solving dead-end problems and bottleneck situations, or preventing them before they happen, is among the topics scientists study today. In Figure 1, cases showing the traffic stream of people moving in opposite directions obtained in this study are displayed.

It is stated that there is less “noise” in situations in which there is a reduced amount of irregular behavior taking place. The term “noise” is used to define concepts that can be disruptive human relations. The higher the noise, the more the degradation of human relationships, and as a result, a disruption or even an arrest (freezing) may happen regarding social events. The elevated temperature of a melting solid material provides it with the properties of a fluid, whereas in social events, an increase in temperature ends up with a jam and freeze in social life. In Figure 1a, a pedestrian traffic flow in which there is less noise present – in other words, a situation that characterizes ideal relations among people – is displayed. Here, it is observed that people with yellow marks have a stable flow towards the left and those with red marks move towards the right side. They do so via lanes of people going towards both directions. A stable flow indicates that the system is not frozen (not in an arrest), or free of a bottleneck. In such a flow, relations work in such a way that fluidity results.

Figure 1

An intermediate noise level causes an increase of irregular behaviors (in other terms, unpredictable human behavior) and shows the presence of serious problems that are experienced regarding the relationships among people. The corresponding situation for this case is shown on Figure 1b. Here, the pedestrian traffic is now jammed and the flow is almost halted. It is impossible for lanes to form since irregular behaviors are above a certain critical level. For a system to be rescued out of this state, oscillations of sufficient magnitude are necessary.

If the situation in Figure 1c occurs, forming a vertical interface (please note the vertical interface that separates people going left and right), this case is called a “frozen state” and much bigger oscillations are required to get out of this state. Figures 1a, 1b, and 1c exhibit before our eyes how elevated noise affects pedestrian traffic: an increase of the noise in the system (for instance, an increase in the number of people who do not stop at red lights and do not continue on green) changes it from a fluid phase to a frozen one, resulting in gridlock. It is possible to compare the increased noise of the pedestrian traffic to an increase in temperature; the elevation of temperature also causes an abundance of irregular movements inside matter. Just like that, the rise of heat in a society due to a particular issue (like turmoil or other problems) may generate an increase in chaotic behaviors. Let’s try to explain this with certain events happening right now.

Let’s think about motor vehicle traffic in any city. If every individual driver observes the rules of the road, this means a low temperature – less noise, and little traffic. Fluidity is present here. On the contrary, if there is not any consensus in terms of traffic rules among the citizens – in other terms, if majority of the people are failing to abide the rules – there will be “heat”; the noise will be high, and there will be a traffic jam. If drivers cannot assess the rules at a four way intersections, or if people with no knowledge of red, yellow, or green lights are driving, a city will have a major problem with traffic.

When a freezing event takes place, waiting becomes inevitable. Unfortunately, most people don’t like waiting. Thus, such “freezing” events should be avoided, so as to keep citizens happy. For example, public announcements of road closures due to scheduled road works limit the reactions against traffic problems on certain routes. However, if traffic is announced and no reason is given, people might still be very unhappy.

For a second example, let’s consider a judiciary system. Just like the example of motor vehicle traffic, the presence of irregular moves independent from rules can lock a legal system. If laws are insufficient, or existing laws are not universally implemented nationwide, or the laws are executed and interpreted differently according to individuals, it is inevitable for a bottleneck or a freeze in the legal system. Actors within the system may anticipate a “freeze” about to happen. People in a state of anticipation need to be convinced and satisfied pertaining to legal practices. Otherwise, they may not enforce the laws properly, and legal chaos may ensue.

Freezing by heating may also apply for certain economic processes. Some economic uncertainties or some actions of unknown cause can be considered as noise by elements of the economy, thus enforcing a behavioral change that is able to affect the entire economy. Therefore, any applied change is followed carefully by the actors of the market and these actors must be satisfied about the changes taking place. Higher noise levels and dissatisfaction of members who are waiting affects the liquidity of the market and can lead to the withdrawal of funds. Withdrawal of money negatively impacts the parties who are in need of cash in various ways and the economic system gains momentum towards a “frozen state.” Negative factors are not the only reason for a bottle neck. Conservation of balance and the fluidity of the economic system are considered as the essence of this issue.

The principles briefly given above can also be applied to socio-psychological events. It is impossible not to encounter a bottleneck for a society consisting of members who are aggressive, stressed, or have less knowledge of their destinations. If a decision can be made with a peaceful state of mind and there is no doubt present regarding current practices, patience becomes the most important parameter. Hence, until a state of balance is established, it is advised to wait with understanding and patience. Patience is a healing aid that plays a role in reducing the temperature in all bottleneck situations.

Fasting prayer is very important for people in terms of gaining this habit. Even for a person who observes fasting one day or two in a week, it becomes more possible to deal positively with any bottleneck situations encountered that week. Another way to lessen the impact of a bottleneck is living to be aware of the fact that each event may serve a purpose. As Nursi stated, each negative or positive event that has been experienced has a purpose. Every event will be over once its purpose is reached. For a sincere believer who is aware of this, realizing that patience also means to appreciate time; thus, it is possible for him to disperse the negative elements that this waiting will bring.

It is possible to expand the “freezing by heating” phase transition to various different mediums across many other disciplines. However, the only necessary element in all of them to prevent such freezes, or to break present freezes, is the reduction of noise (temperature). It’s possible to find guidance by acknowledging that this world is a place of wisdom and service, and rewards do not always come in this life.

References

1. Dirk Helbing, Illes J. Farkas, Tamas Vicsek, “Freezing by Heating in a Driven Mesoscopic System,” Physical Review Letters 84, 1240-1243 (2000).
2. H.Eugene Stanley, “Non-equilibrium Physics: Freezing by Heating,” Nature 404, 718-719 (2000).

Once I could see God in one thing – even though it was the vastest, most mysterious, and perhaps most obvious example in creation – I was able to see God in almost anything.

Before, there was no meaning. There was no cohesion. There was no contentment. Instead, there was sorrow. There was an endless search for pleasure. There was a fear of death, but also a fear of life. And there were questions. There were always questions. And the answers I found only made me ask more and more questions. I was under the impression that there was no certainty, no order, no higher meaning – that I was asking questions that were not meant to be asked.

To put it another way, during this time in my life, I had the perception that knowledge and belief were incompatible – a relatively common idea, as I have found. Many will say that science goes against religion. Some will choose religion; I chose science, because in many ways, it appeared to be the more difficult one to dismiss. In retrospect, I know that my conception of religion was simply wrong, that the two really can be, and are, compatible. After all, not only did God give us intellectual capacities for a reason, but also, the book of divine revelation cannot contradict the book of creation. Would that not undermine God’s wisdom? Regardless, at the time, my belief had melted away due to my increasing awareness not only of science, but also that scientific accuracy was lacking in my faith. As a result, a never-ending barrage of questions ceaselessly entered my head.

To me, life had no real meaning. Everyone at some point asks, “Why am I here?” Before, my answer to this question was, “To make myself happy.” Therefore, my life was centered on myself – I was the center of the universe. No one else mattered. All of my time was spent on seeking pleasure – physical pleasure, material pleasure, intellectual pleasure. I was focused on finding happiness, and I thought this happiness would be found in gaining the acceptance of others, in having many possessions, in being well liked, in indulging in worldly pleasures. In my career path, I did not desire to make a difference in the world nor was I concerned with earning lots of money, strangely enough – I simply wanted a job that I adored: a job that made me happy. Mind you, what this job was, I did not know, but this was my goal and my primary concern.

I did not know the meaning of life, nor did I know why or how I got here, so seemingly, the only reasonable solution was to enjoy the life that I had. Why I had this life was of little import. So, I set off on a journey in search of lasting, worldly happiness, but I did not find it. Instead, I found that this abstract entity was very elusive. When it seemed I had found real and genuine happiness, I would lose it. The pleasures I partook in on this journey were only transitory, so when the contentment I found in them was gone, there was only pain. This left me still feeling empty, feeling that there was no real deep and lasting contentment to be had in this world. It was akin, in a way, to an addiction. I was always trying to get my “fix,” and over time, it became increasingly difficult to satisfy myself, to hide the pain – pain that resulted from wanting, from desiring even, to live a life of higher meaning, all the while not knowing how to attain it.

Regardless of the fact that, initially, it was knowledge and questioning that caused my belief to wither, during this time, I was not at all interested in increasing my knowledge – not in reading or in learning. I was simply apathetic; perhaps I had become burnt out due to knowledge causing me to ask questions that seemed unanswerable. Pondering frustrating existential questions was not pleasurable, nor was it, seemingly, a path to happiness, so I just ignored my thirst for knowledge and answers. In lieu, I spent my time on shallow frivolities, but this got very old, very fast.

Despite my pulling away from intellectual endeavors and from belief, there were still some topics that occasionally caught my interest. It was my seemingly innate fascination with space, with the universe, that made me reconsider my belief in God. I could not look at the order and perfection inherent there and think that it was all just a random occurrence. This was simply impossible to me. There are innumerable examples, but for one, if the earth were any closer to the sun, it would be too hot to sustain life, and gravity would be too strong. If it were any further away, the opposite would be true – it would be too cold and gravity would be too weak. As I see it, the earth’s distance from the sun could not have been a mere coincidence. In the words of Nursi, the universe is a “macro Qur’an,” and I was able to discern this even before my personal beliefs were solidified; I could clearly see that the universe is brimming with God’s signs, and that the sheer vastness of it is a testament to His infinity and oneness.

Once I could see God in one thing – even though it was the vastest, most mysterious, and perhaps most obvious example in creation – I was able to see God in almost anything: the tides of the ocean, the composition of the atmosphere, a seed sprouting into a small tree, the uniqueness of a fingerprint, the utter complexity inherent in an atom, despite its size, or even the varieties of difference – and remarkable similarity – between people. To emphasize this, God repeats over and over, “Then which of the favors of your Lord will you deny?” And it had thus become clear – I cannot deny any of them because all of creation is a reflection of its Creator.

At this realization – that God does indeed exist, for He manifests Himself everywhere – my thirst for knowledge made a swift resurgence, but first I had to forget everything I had previously known about my beliefs, my desires, my goals, my life’s purpose – I even had to forget everything I knew about myself. I had to gain a new mindset and refine my worldview. I had to reevaluate my own personal motto. I had to change even the minutest aspects of my daily routine. There was so incredibly much to learn, as there had been so much time that I had wasted. The turnaround seemed hasty or even abrupt, but it had been in the works, covertly, for a long, long time. Those times when I pushed aside my questions? They were the final moments of calm before my life would be flipped upside down, losing every last bit of resemblance to my previous life.

Now, I feel guilt if I waste too much time. I have, seemingly, almost a compulsion to learn something new every single day. I read – constantly – about anything and everything. My desire for knowledge is no longer in a vacuum, as it was before, because now I know that knowledge could be used to increase faith and belief, and faith and belief could be used to increase knowledge. For every question of faith or of the nature of life that knowledge led me to ponder, belief gave me answers – answers that satisfied me. The satisfaction was in seeing how knowledge and faith were not only compatible – they were intertwined. I could see the perfect order in everything created by God, and I could see all of the problems inherent in the society created by man – materialism, narcissism, and a lack of faith. But these problems were not only on the macro scale of society; on the micro scale, they had been my problems. They had been the obstacles to my happiness and contentment. I had life, and I had knowledge. Faith was the missing piece.

I still partake in worldly pleasures – I am not an ascetic, nor do I claim to be. These pleasures, however, are not the means to happiness. Belief is the means to happiness. Worldly pleasure is a gift from God, and so I experience pleasure for what it gives me – temporary pleasure. I no longer expect it to give me lasting contentment. Faith gives me that. Life for me is no longer this endless search for worldly satisfaction because happiness cannot be found among things of this world; it can only be found through certainty of belief. With certainty of belief, I now know that even pain and suffering has a greater purpose – everything has a greater purpose.

Before, I wanted happiness at any cost. That was my motto. Now, I focus on increasing my belief and my faith. I study, read, and reason since exercising my intellectual capacities is a way to do that and because I must not waste the gifts I have been given. My life has a different purpose now – to contribute to the greater good, to use my free will responsibly, to live rationally and reasonably, and to remember God in everything I do. One can always strive for this and never tire of it because there are infinite rewards and there is infinite room for improvement. So now, the motto that I live by is “knowledge to increase faith, faith to increase contentment.” Now, I have found all of the missing pieces.

The phosphate and nitrogen compounds found in the waste material that are released into the environment go through some biological processes and are transformed into nourishing salts for the phytoplankton. When there is an increase in temperature, these salts may cause some of the phytoplankton to grow and reproduce excessively. The toxic materials released by some, and the use of excessive oxygen, are harmful to other organisms.

Another example of pollution is related with algae. When the number of microbial plants called algae reaches one million per cubic decimeter (1 million/dm3) of water, the consumption of oxygen required in order to mineralize, and break-down the organic materials found in the water increases, and therefore a compound of toxins which pollute the water, such as hydrogen sulfide (H2S), are released. This pollution can cause the death of fish and other organisms which live in the water. As a result of the reduction in water quality, an increase in the type of algae called cyanobacteria occurs and the biotoxins that they produce threatens human health.

More than forty types of algae produce various toxins. Some of these toxins damage the human liver, some attack the nervous system (particularly the brain), some can cause allergic skin reactions, and some can even induce cancer. The release of domestic, industrial, and agricultural waste and the high percentage of nutrients (such as nitrogen and phosphor compounds) into the aquatic ecosystem can cause an excessive increase of algae in the waters. This algal bloom in fresh water is referred to as eutrophication. In oceans, it is referred to as red tide because the water appears to be a reddish color. Both present a significant environmental problem.

In low doses humans are exposed to these toxins by the consumption of drinking water. In Brazil in 1988, almost 2000 people developed gastroenteritis over a forty day period due to the consumption of drinking water contaminated by these toxins, and eighty-eight of them died. In South Australia, as early as 1878, many sheep, horses, dogs and other animals died as a result of drinking water from Lake Alexandrina, which was covered by scum caused by an aglal bloom called Nodularia spumigena.

Mussels, a delicacy eaten and enjoyed by many, accumulate large amounts of toxins because they feed on phytoplankton. One study found that in fresh water mussels (Mytilus galloprovincialis) that fed on cyanobacteria, almost 10.7 g toxins per gram of bodyweight was accumulated. This is also the case in marine mussels. It has been determined that these toxins in gradually increased concentrations are passed onto organisms higher on the food chain by consumption. Accordingly, we should always consider the potential risk factors before consuming shellfish.

Biotoxins are released into the water after being broken down by algae. Thus, when an algal bloom reaches high levels, there is an increase in the density of toxins in the water. As these toxins dissolve in the water, purifying the contaminated water requires not only expensive, but also advanced technology methods. Unfortunately, it is impossible to remove this waste in many of the existing refining plants. The toxin concentration in drinking and utility water should be reduced in regions where drinking water is obtained from lakes by mixing it with uncontaminated water, particularly during the spring when the algal bloom occurs. Thus, reducing the amount of biotoxins in the water to a level that will cause minimal harm to aquatic organisms should help to reduce the risks to humans.

Many types of waste released into the environment cause damage, which adversely affect humans. Polluting the environment may be easy, but purifying the environment of this pollution is a very difficult task. Indeed, humans were not created to act irresponsibly and destroy the universe in which they are mere guests. On the contrary, the human is a delicate guest with sublime duties. Protecting the natural resources provided for our needs and utilizing these resources in the most productive manner, without disturbing the balance of nature, is a duty of every human on earth.

References

• Pouria S. de Andrade A. 1988. “Fatal microcystin intoxication in haemodialysis unit in Caruaru, Brazil.” Lancet 352:21-26.
• Carmichael W.W., Azevedo S.M.F.O. 2001. “Human fatalities from cyanobacteria: Chemical and biological evidence for cyanotoxins.” Environ. Health Perspect 109: 663-668.
• Codd G.A., Bell S.G., Kaya K., Ward C.J., Beattie K.A., Metcalf J.S. 1999. “Cyanobacterial toxins, exposure routes and human health.” Eur. J. Phycol. 34:405-415.

Only 0.15 % of the energy that reaches the earth is used by the plants and the algae as a source of energy for photosynthesis. The energy that is stored in the form of chemical energy within the photosynthetic plants establishes the source of energy for the food that is consumed by the creation. The past creation, as a result of the physical-chemical processes, was fossilized and solar power has been stored in the form of fossil fuels (oil, coal, natural gas).

Energy consumption and the environment

Energy consumption is viable for every form of work; the waste is what remains in the environment. This waste does not pose a problem as long as they do not damage the sensitive ecologic balance. However, rapid industrialization and urbanization, which lead to excessive amounts of energy consumption, result in environmental problems. Since industrialization-urbanization is directly related to energy consumption – particularly with fossil fuels – industrialized countries are more vulnerable to experiencing environmental problems. In today’s world, it is climatic change – a product of global warming – among these problems that is of the greatest global importance.

The increase in the proportion of carbon dioxide, a greenhouse gas, in the atmosphere is the main factor for global warming. This increase is directly related to the consumption of fossil fuels. The rays of the sun, which are reflected from the earth, are trapped by carbon dioxide gases (chlorofluorocarbon, nitrous oxide and other greenhouse gases, such as water vapor) in the atmosphere, and they can not return to space. This, in turn leads to the atmosphere heating up (the greenhouse effect), eventually leading to an increase in heat throughout the world.

The main reason for the increase of carbon dioxide in the atmosphere is the consumption of fossil fuels (77%) and the decrease in the number of forests (23%). Coal gas is normally the last product of the anaerobic processes in nature. In recent years human intervention played the main role in this abnormal increase in gases. Playing an important part in this process is the expansion in rice fields (38%) in order to feed the increasing population, natural gas extraction and its transfer (16%), an increase in the number of cattle (14%), coal mining (12%), and the oxidation of produced biomass (6%). Chlorofluorocarbon is included in industrial products. As for the nitrous oxides, they are the by-products of reactions in the nitrogen cycle in nature. In recent years, as a result of the increase in the use of the nitrogenous manures (85%), forest fires and other fires (11%), and the oxidation of the produced biomass (7%) there has been a rise in nitrous oxide. Consequently, the rapid increase in greenhouse gases in the last years has lead to a 0.5°C increase in the average heat of the earth.

If the greenhouse gases continue to be accumulated at this speed, then by 2100 the average heat of the earth will record an increase of 2–4°C compared to the period before industrialization. Eventually, there will be a greater melting of the glaciers at the poles, which will lead to 0.5–1.5 % increase in sea level. Thus, residential areas by the seaside, agricultural areas, wetlands and industrialized areas will face the danger of being flooded. Moreover, the risks of climatic changes and desertification will become much more severe.

Some countries are investigating how to calculate the probable effects of a decline in water, food and energy resources and what precautions need to be taken accordingly as a result of global warming. In this sense, the problem was clearly indicated during the summit meetings in Vienna (1985), Rio (1982), and Kyoto (1997), however, they have not been sufficient to provide a solution.

Another important problem arising from the overuse of fossil fuels is the damage to the environment caused by air pollution and acid rain. During the consumption of fossil fuels, CO2, NOx, and SOx are emitted into the atmosphere and these, combining with water vapor, lead to the formation of carbonic acid (H2CO3), nitric acid (HNO3) and sulfuric acid (H2SO4). While normally the pH of rain water is 5.5–6, with these acids it falls down to 3.5–4. This and the resultant dissolution of the metals in the water pose a threat for both the land and the aquatic ecosystems (e.g. a decline in fish species in many lakes) and impair the ecologic balance.

The impact of alternative and renewable energy on the environment

The negative impact of fossil fuels on the environment and the decline in their reserves has accelerated the search for new energy resources. Even though nuclear energy is not a renewable resource, today it has come to be regarded as an alternative energy resource all around the world. Hydrogen, too, is another growing alternative resource. Geothermal energy is also a renewable energy resource, yet it is mostly restricted to the region where it originates.

With current technology, it costs us more to use solar energy rather than to extract fossil fuels. Moreover, there is a great need for the development of new technology that is aimed at producing wind, hydroelectric, bio-energy, tidal and wave energy in the most efficient way at the lowest cost.

Defeated by their ambitions, human beings, particularly in the last century, have destroyed the world and the environment that has been entrusted to them. Since the global impact and the cost of this process only emerged recently, it was too late before human beings realized that they needed to shift from energy systems based on fossil fuels. All the worries and concerns that have surfaced today is not because we have finally realized that the earth has been entrusted to human beings, but simply because the future seems to be promising nothing but destruction. Thus, the real solution to the problems is not related to acting to find a solution to the problems, but rather in being in compliance with the measures of the actual Owner of the world and the universe and avoiding form all types of extremism.

References

• Spiro Thomas G. and Stigliani William M. 1996. Chemistry of the Environment, Prentice Hall, Upper Saddle River, New Jersey, USA.
• Godish Thad. 1997. Air Quality, CRC Lewis Publishers, Boca Raton, New York.
• World Energy Outlook. 2004. International Energy Agency.

Even if work done is for the sake of good, if it does not occasionally add color to life, then one can experience boredom beyond monotony. The Prophet Muhammad, peace be upon him, prevented those who gave themselves to worship from worshiping in a way that would bring boredom.

One of the heroines of this situation was Zaynab binti Jahsh, a sultan of the women’s world. She was a woman famous for her devotion to worship and her generosity. She took the Prophet as a role model and behaved like him as best as she could. A member of a noble family, our mother Zaynab was one of the honorable of the Quraysh tribe. Perhaps due to a spiritual state derived from her heritage, she experienced inner turmoil when she married Zayd. However, she was to be the wife of the Blessed Prophet. God made their marriage in the heavens with the verse: We united you with her in marriage (Qur’an 33:37).

Our mother Zaynab was so devoted to worship that she stretched a rope between two poles in the masjid so she could lean on it when she got tired. Seeing this rope, the Messenger of God said as a warning:

“Untie the rope. When you get tired, rest, and after you rest, perform worship. If you do not show weariness, in a similar way, God will not show it towards you and will give you what you want.” At another time he stated, “When you are sleepy while you pray, it is probable that the favorable prayer you would make will turn into an unfavorable one,” thus recommending the performance of worship after rest.

Similarly, it is certain that constantly doing work along the same lines will bring on boredom. In order not to allow this to happen, there is benefit in visiting a different place within your means and to becoming busy with other things. Also, in order to increase your love and enthusiasm and to increase your motivations for good service, it is helpful to see people who share the same ideas and feelings that you do.

In fact, you can stay in such a place as a guest. Also, you can visit places of historical heritage and institutions established for good service to others. In this way, you both relax and maintain your liveliness. To the contrary, your body might relax in places where heedlessness and excitement are promoted, but your spirit cannot. Actually the body’s full relaxation depends on the spirit’s being lively and alert. If the hope is that the spirit relaxes as well as the body, then you should visit people who show devotion to worship and good virtues and who are good examples with the way they live. I can comfortably say that money used for gasoline and other expenses in these visits will be considered charity. In this way, we will have given the best charity for our families, and we will have taken them out for pleasure as well. Even if vacations made for purposes other than these relax the body, they also allow for the prolongation of heedlessness and some subtle faculties of human spirit may be destroyed.

In summary, those with believing hearts should not neglect to go on vacation on certain days of the month or year, within means, for the purpose of their own and their family’s relaxation. It is very important for the sake of continued vitality.

When we have been sitting or lying for a long time we can suffer from orthostatic hypotension due to an insufficient operation of the sympathetic nerves.

When we are lying down, the blood pressure in our arteries is pretty much equal throughout the body. When we stand up, the blood pressure is affected by the gravity and increases in the vessels under the heart, while decreasing in the brain. If we lie down again, the blood pressure in the arteries balances once again. If these changes cannot be naturally controlled, then we may suffer an increase or decrease in blood pressure, which could result in a fatal injury.

There are baroreceptors in the walls of main arteries whose tasks are to measure constantly the blood pressure and to send data (electrical signals) to the brain, informing it about the blood pressure in the body. These baroreceptors are located in the aorta as it leaves the heart and in the carotid artery as it enters the brain. With the onset of hypertension, the frequency of the signals that are sent to the brain increases and this drops in case of hypotension. The center of vessel movement in the brain, with regard to the frequency of electrical signals it receives, perceives a low or high blood pressure.

In the brain is a vasomotor center; this continuously controls the blood pressure and regulates it. This center constantly receives data about blood pressure. If the pressure decreases, the signals of the sympathetic nerve increase. If the pressure increases, the signals to the parasympathetic nerves are suppressed. As a result of sympathetic irritability, the heart begins to beat faster and stronger. It pumps much more blood in a unit of time, and thus the blood pressure increases. The arteries and veins also constrict and owing to this constriction in the arteries, the blood pressure increases further. As a consequence of constriction in the veins, the extra blood that is stored inside the veins is pumped into the heart. Now, as the heart is receiving greater volumes of blood, it works faster and contributes to the increase in the pressure. In the meantime, as a result of the suppression of parasympathetic nerve signals, the heart contracts faster and stronger, thus pumping much more blood.

As the blood pressure rises, the mechanism which is in charge of reducing the pressure via vasomotor center is triggered. While pressure is applied to the sympathetic nerves, the signals that are being sent to the heart and vessels decrease. Thus, the rate of systole and the amount of blood which is being pumped decreases. As the arteries receive less blood the volume of blood in the system falls off and as the arteries and veins expand, the blood pressure falls. Due to the dilatation in the veins, the volume of blood which is sent to the heart also decreases and as a result the heart pumps less blood and the blood pressure drops.

However, by triggering the parasympathetic nerves, the signals that are sent to the heart increase. This helps to slow the heart down and ensures that there is less blood pumping through the system. As a result, the blood pressure which has been reduced via the sympathetic system is reduced even further with the parasympathetic system. At this point, it is necessary for there to be a rapid drop in blood pressure, which is provided by the simultaneous functioning of different mechanisms.

We cannot control this system and it acts extremely rapidly and with great elegance. Even in the systole period, when the heart is pumping the blood and there is a short and sudden increase in pressure and in the diastole period, when the heart relaxes and there is a short and sudden decrease in pressure, the system is in charge and functioning at every second, operating to increase the hypotension and to decrease the hypertension. The average healthy human heart beats 70 times per minute. Consequently, there are 70 systole and 70 diastole stages every minute; thus a normal balance can be maintained by decreasing the pressure, which increases 70 times every minute, and by increasing the pressure, which decreases 70 times every minute; this is how the body maintains a normal balance. In other words, this system functions 140 times every minute. Is it possible that this system, which operates throughout our life, a system that we are not aware of, a system that is so sensitive and vital to our lives, a system the details of which have only recently been understood after centuries of observation could be nothing more than a coincidence?

The pressure regulating system mentioned above carries out other important tasks while we are sitting and standing as well. The amount of blood going to the brain is related to the maintenance of a difference in blood pressure between the arteries and veins and to the recirculation of blood. In connection with hypotension, the pressure in the veins to the brain decreases, in order to partially compensate for the decrease in the arteries. By preventing a decrease in the difference of pressure (perfusion pressure) between the two systems, the continuity of blood going to the brain can be maintained.

In addition, a small decrease in the blood going to the brain can lead to an increase in acidity and carbondioxide in the brain tissues and to a decrease in oxygen; this results in the dilatation of the blood vessels in the brain. When these systems go into action anyone who is not suffering from orthostatic hypotension will have a stable amount of oxygen consumption in the brain when they stand up, and thus not experience dizziness.

In fact, scenes from karate movies are wonderful displays of the perfect functioning of this system. In such scenes, the fighter will jump up, and then suddenly fall to the ground; he will then suddenly spring up and performs different moves. Certainly with every movement, the blood pressure changes suddenly, but as a sign of the Creator’s mercy and grace, the body is able to maintain a balance. Should not the person watching these scenes stand in amazement, thinking: “Oh my God, what an incredible order! How great is Your knowledge, power, wisdom and art!”

As mentioned at the beginning of the article with reference to an actual sad incident, when a person whose sympathetic system is not functioning normally suddenly stands up, they can suffer from dizziness and perhaps even faint due to irregular blood pressure.

For patients suffering from orthostatic hypotension patients, it is important that they do not stand up rapidly. In addition, exercises that encourage the use of leg muscles before standing up will help pump blood towards the brain.

Pause for a minute… What would happen if this miraculous system did not exist? Consider how much time it would take you to merely get out of bed every day!

Finally, I have come to say goodbye to you. As you probably know, there is a saying “Leave the best till last.” I am the greatest of all the organs and systems that have described themselves to you so far. I am an integrative system that forms a chain between every organ in your body. Just as your veins are spread out to carry nutrients and oxygen to every part of your body, I also embrace your entire system like a network, without leaving the tiniest space; I am informed of everything that goes on inside your body. Even if a tiny insect settles on your arm, you sense it immediately. I make you aware of a tiny drop of sweat on your body. I induce pain in suitable measures to inform you of any illnesses in your inner organs. In fact, I not only inform you, I also warn you to seek help.

However, it is hard for me to describe myself. When you hear the words “nervous system,” what comes to mind is a cluster of cells called neurons. But this is a great mass of cells, and we should always remember that we are referring to the most complex matter in all of creation. The very important main nervous systems, which are very close to one another, are the huge masses positioned beneath the skull, the extensions of my system and secondary nervous system; this latter is spread out through various regions of the body. It would take up too much of your time to describe each region and branch of my system individually to you each month, but in this way I could prove what a perfect and incredible duty each of them performs within your body. However, I will try to explain the subject briefly to avoid boring you. Nevertheless, please forgive me if I ramble on too much; we are describing the most excellent organ created by God so it is inevitable that there will be some complicated matters that need clarification.

Instead of allowing each of my sections to describe themselves to you individually, I will speak on their behalf as the “brain.” It may be easier for you to understand the system if we divide it into two. One of them is me and the nervous system which I lead; we can briefly describe this as the thalamus, hypothalamus, cerebellum, the medulla, and the spine. The other part is the peripheral nervous system, which emerges from the central nervous system and is distributed, rather like fiber optic telephone cables, throughout the entire body. In addition to me, the brain, and my two large cerebral hemispheres, there is another smaller section, which is known as the brain stem. The brain and its cerebral hemispheres and the sections of the brain stem which are protected beneath the skull (the cerebellum, medulla, thalamus, and hypothalamus) are very important. The spinal cord, which is also a part of the central nervous system, however is not in the skull, but positioned within the vertebrae that constitute the spine. Due to its connection with the central nervous system, any damage to the spinal cord can endanger life.

Although damage to regions of the body where the nerves are distributed from the central nervous system may cause paralysis, or functional disorder for the specific organ, such an incident is not life threatening.

If you recall, when the heart and circulation system described themselves they boasted – indeed the veins also seemed to brag a bit when they stated that they measured 75,000 miles (long enough to go around the world almost three times). But the nerves are approximately 477,000 miles, long enough to stretch from the earth to the moon, and back again… the nerves which are distributed throughout the various parts of your body measure 250,000 miles, and the total length of the central nervous system is 228,000 miles. Almost 200,000 signals pass through just one cell at a time, which means that every moment thousands of signals pass through millions of my cells all throughout your body, and flow from the central nervous system to the whole body and then back to the central nervous system. There are about 30 billion cells in my system. 10 billion of these cells are in the cortex, 10 billion in the cerebellum, and the remainder forms the structure of the nerves and other sections. As a comparison, a fly’s brain contains 100 thousand cells, and a rat’s brain has 10 million cells. The total number of connections and contact points (synapses) that my 30 billion cells use to send and receive signals is 100 trillion. The number of combinations that these connections can establish to send signals to one another is greater than the number of atoms in the universe. At the beginning of a thinking process, the number of cells activated is between 10 and 100 million, and according to the depth and intensity of the activity, these figures can increase to astounding numbers. Every second 4 billion signals are exchanged between the left and right hemispheres. When you were an embryo, just a few weeks old, I consisted of 92% water. When you were first born, the ratio of water was 90%. And when you were fully developed, the water ratio remains at 77%. Peter! Can you imagine, a heap of mass consisting of 77% water, the remainder made up of various element. Our Lord, the bearer of eternal power places me in you, in the head of the most honorable creation, and with me you form civilizations; you invent and discover. And even more important, with my mediation you have the ability to contemplate and reach your Creator. What we are learning about here is how with me you are able to recognize the wisdom of the entire universe. The electric signals of the various sense organs, such as the eyes, ears, nose, tongue and skin, all of which have previously described themselves, are transmitted by the receptive cells on various wavelengths; these are then conveyed to you in the form of sight, noise, smell and taste. In fact I am inducing you to write these words at this very moment. The evaluation of everything you do passes through me, but you are not even aware of it. When you walk, eat, talk, speak or sleep, the information I receive from every part of your body is reviewed and responded to in a suitable manner. Dear Peter! Could a single nucleus of a single one of my cells possibly position itself alone?

The Lord has created me so magnificently that you are still only aware of a very few of my mysteries. Each of the sections that I mentioned above has a distinct and important vital function. On their behalf, I will briefly explain their duties: The cerebellum is the nerve center from which the harmony of balance and muscle movement is controlled. As this section of me has no sense of perception, it is impossible to voluntarily change the functions of this region. The pyramid shaped medulla oblongata, which connects the spinal cord to the midbrain and the pons; the latter constitutes the other end of the brainstem through a hole in the back of the skull in the form of the spinal cord and enters into the vertebral column. Here, there are many nerve centers which regulate autonomic nervous system activity, such as the heart rate, breathing, and digestion process. This is also the center from which the reflexes are controlled, the body’s inner environment is regulated, and this center, working with the cerebellum also controls movement and coordinates signals received from the nerves of inner organs. Moreover, activities such as excitement and sleep are also controlled here in collaboration with the thalamus.

The thalamus lies between the brainstem and the hemispheres of the brain, performing a function rather like a junction or relay station. This section gathers all the signals sent by the sense receptors, except for those from the olfactory (smell) receptors, and conveys these signals to the cortex reflecting the information; there is also a role played in consciously identifying sensations such as pain, touch and noise. There is also a role played in the sensory changes that occur with the perception of senses in our consciousness and awareness, as well as in the regulation of sleep and paying attention. The hypothalamus, which is located below the thalamus, is an important center that controls sexual senses; the sensations of pain, pleasure, hunger, and thirst, as well as blood pressure, temperature and other functions of the inner organs. It also performs the important duty of regulating hormone release. The nerve fibers that enter this center, which is the location of a very complex network of nerves coming from the olfactory bulb, thalamus, and the frontal lobe, reach the autonomic nervous system, the reticular formation in the stem section, and the posterior lobe behind the pituitary gland (hypophysis). The pituitary gland, one of the most important systems that earlier described itself in the endocrine system, produces hormones that stimulate secretion in the anterior section, as well as the oxytocin and antidiuretic hormones which are stored and released from the posterior pituitary.

On the base of the deep grove that separates the two hemispheres of the large brain there is a callus-like body; this is a bundle of axon (nerves) called the corpus callosum which connects the two hemispheres. Because the nerve fibers cross and change direction in the medulla, the left side of the brain controls your right side, and the right controls your left. Although my two hemispheres may look like a reflection of one another, there are some variations in their duties; for example, the left hemisphere controls speech, but the section which controls the perception of location is in the right hemisphere. Whilst you use the left hemisphere for duties that must be performed in a specific order (activities such as adding and subtracting or buttoning a shirt), you use the right hemisphere in thinking with images (for example, mapping the route from your home to the market). If the callus substance that connects my two hemispheres did not exist, there would be no communication between the two, therefore, you could read the word “fish,” but you would not be able to picture the image of a fish in your mind without the right hemisphere to achieve this.

The brain, the grey-colored mass of folds and grooves that covers the top of my anatomic hemispheres, the region where the main stems of my cells are found, is called the cortex or grey matter; the lighter colored matter that lies beneath this, the region where the axons (stems of neurons) are found, is called the white matter. My cortex region, which is composed of six layers of cells, is the center where the sensory signals are received and analyzed and where voluntary muscle movement is controlled, while also being the center of activities, such as learning, reasoning, and remembering. My two hemispheres, the focal point of conscious activity and thought that forms the large brain, constitute 85% of the whole brain. When you were first born I weighed 400 grams, but I grew very quickly, and by the time you were a year old I weighed 800 grams. When you were four years old, I weighed 1,200 gr. However, my growth began to slow down after the age of seven, and when you reach twenty, I will weigh approximately 1,379–1,434 grams. When you begin to pass your first youth, my weight begins to decrease every year by 1 gram, so when you reach seventy-five, I would have shrunk in comparison to when you were twenty. The reason for this decrease in weight is that approximate 50,000 neurons die, or cease to function daily, after you reach the age of twenty. The body cells of the cartilage, bone, skin, ligaments and the liver divide, regenerate and increase in number; however, the nerve cells that are part of me continue to increase until they reach the figure set out for you when you were formed in your mother’s womb; they then lose the ability to segregate. So if there is any damage, relative functions fail because the cells in that region have died. Then the question arises: As there is no increase in the numbers of cells, how does the weight continue to increase until the age of twenty? Well, there is not an increase in the numbers of cells; rather, there is an increase in the number and growth of connections between the cells and this is how my weight increases. Of course, nutrients are added to build and stimulate these connections. Subsequently, with age these connections begin to decrease. With ever experience you have, all the things that you learn or see during your youth these connections increase, and in turn this increases my capacity for thought and reasoning. If you continue to activate your brain by reading, writing and other social activities in old age, these connections continue to increase. Even if there is a decrease in my cells, you are able to continue your usual activities without losing any functions of the brain. But as soon as you say that is enough, it is time for a rest, my cells begin to withdraw their connections immediately, and in time you will certainly see the difference in my capacity. If the cells in my central nervous system are injured or damaged, they cannot repair themselves. However, if the cell bodies of my cells in the peripheral nervous system are not damaged the stems are repairable.

Thanks to this special feature if a severed arm, leg or finger can be carefully replaced with microsurgery, the nerves can repair themselves, and the limb will continue its normal functions. The visible cause of this characteristic is found in the nerves of the arms and legs, but not in the brain or spine, is the casing that surrounds this bundle of nerves that transmits signals for the cells to grow. Even with the greatest of techniques, no surgeon could sew the severed nerve fibers. However, thanks to the nerve casing that holds these fibers together (like the plastic that covers the electric cable, consisting of thin wires) the severed limb can be replanted. Then with guidance from this outer casing, each of the hundreds of fibers found inside grow 1 mm every day, and in a period of between 1 month and a year, they will begin to function again.

Irfan Yilmaz is a professor of biology at Dokuz Eylul University, Izmir. 

The world hypertension statistics

Almost a quarter (26 percent) of the world’s adult population suffers from high blood pressure. It is estimated that this number will reach 29 percent by the year 2025. These average statistics based on the adult population of the world includes people of various age groups and from different countries. The risk of hypertension increases with age. While the figure for 20–29 year old males is 13 percent, it increases to 40 percent between the ages of 50–59, and reaches over 60 percent after the age of seventy. Although there are slight variations in women, many of the figures are almost the same (Figure 1).

These figures are quite striking; one out of every two people over the age of sixty suffers from high blood pressure. As for those in their seventies, the figures have already reached almost 70 percent and are expected to increase even further as this group ages. Many diseases in the adult population remain at 1–2 percent; therefore, these figures convey just how common and serious hypertension really is.

The regional distribution of hypertension figures

In contrast with the estimated numbers given above, the figures for hypertension in the different regions present significant variations. Statistically, the number of hypertension cases increases according to the welfare status of the society. In economically developed countries, 37 percent of the adult population has high blood pressure, which is a considerably elevated number in comparison with the world average of 26 percent. Furthermore, 70 percent of the males and 80 percent of the females over the age of seventy living in economically developed countries suffer from high blood pressure. However, in economically underdeveloped countries, the number of hypertension cases is very low.

The hypertension rates in China and India are well below the world averages, with males at 17 percent and females at just 14 percent (Figure 2). In some societies, for example in the Amazon’s catchment areas, the Yanomami Red-Indians, and tribes in the highlands of Papua New Guinea, few cases of hypertension can be found, and blood pressure among these groups does not tend to increase with age.

The reasons for the increase in hypertension

There is a genetic disposition to develop hypertension. The recent studies reveal that high calorie foods, a high level of salt intake, the lack of physical activity, and alcohol intake all play a significant role in the increase of hypertension. By examining these reasons alone, we clearly see how important the prohibition of alcohol is and the Prophet’s words of wisdom advising us to eat less bear on our lives and prosperity in both this world and the hereafter.

Excess of body fat (obesity)

Another recent health phenomenon is the huge increase in people suffering from obesity, mainly due to excessive eating and the lack of exercise. Studies related to disease outbreaks (epidemiological studies) show that obesity is clearly associated with hypertension. These studies also reveal a significant increase in people suffering from both obesity and hypertension. According to these studies, 78 percent of the male and 65 percent of the female cases of hypertension are connected to obesity. Similar studies carried out in various countries confirm that a large number of people with high blood pressure were overweight and that losing weight substantially reduced their blood pressure levels. In fact, the blood pressure in some was reduced by losing weight alone, without the need of any medication.

Many studies also evaluated the connection between obesity and hypertension by measuring the level of the leptin, the hormone that controls the appetite, in the body. High levels of leptin induce stimulation in the sympathetic nervous system and shrink the veins (causing an increase in blood pressure). Another reason for the increase in the activity of the sympathetic nervous system of overweight people is the rise in insulin levels, which in most people can be controlled by diet. Finally, the kidneys of overweight people retain greater levels of salt and water, which causes an increase in blood pressure. These conditions, which on many occasions can prove to be very serious, are in fact contrary to the intended physical state of human creation, as the Prophet Muhammad, peace be upon him, declared in these words of warning: “What I fear most for my followers is a large stomach, excessive sleep, idleness, and the lack of certainty (in faith).”

Excessive salt and alcohol

Evidence from both experiments on animals and clinical studies proves that the excessive intake of salt increases blood pressure. In animal experiments, a high intake of salt in the diet of rats showed a rise in blood pressure, which resulted in strokes. In another experiment, more than 0.50 ounces of salt was added to the diet of several chimpanzees for a period of twenty months. The studies showed an increase of 33 mmHg in the systolic blood pressure and 10 mmHg in the diastolic blood pressure, and when the salt was removed from the diet, the chimpanzees’ blood pressure returned to normal levels. Indeed, salt is an important nutrient for the human body. Sodium, potassium, and calcium salts are essential for all nerve cell activity, for muscle movement, and for the osmotic balance of body fluids. Medical science of today stresses the importance of natural foods, and bread, an important part of our diet, meets the body’s daily requirement of sodium. Thus adding salt to our food and exhausting the kidneys is not necessary.

Various clinical studies on humans have shown that excessive salt in the diet increases blood pressure levels. Salt has been used in the human diet for the past 8000 years, since the beginning of agriculture and animal farming. A human’s normal requirement of sodium is 8–10 mmol/per day. However, in economically developed countries, the daily sodium intake of most people has risen to 140–150 mmol per day (8–9 grams), almost 14–15 times more than the normal physiological requirement. In a study carried out on the subject, 10,000 blood pressure sufferers in 32 countries were closely monitored, and the results showed that as the salt intake was reduced, blood pressure levels dropped. In another study, 24 hour urine samples were analyzed, and here too, a low sodium diet showed a decline in blood pressure.

One of the many health risks of alcohol is its serious affect on blood pressure. Clinical studies have proved that the excessive intake of alcohol causes high blood pressure. The frequent cases of high blood pressure in societies of the former socialist countries and economically developed countries of the present are mainly connected to the excessive intake of alcohol.

As a result, the number of high blood pressure cases in the world has exceeded that of contagious diseases, and this is closely connected to our eating and drinking habits. If humans continue to excessively eat and drink as they are at the present, most people will be suffering from high blood pressure in the very near future.

1. Genes and inheritance
2. Obesity
3. Lack of exercise

The diagnosis of diabetes is described as a level of sugar that is above a certain amount in the blood stream. In fact, diabetes itself is the metabolic disorder of three food sources: carbohydrates, proteins, and lipids (Cholesterol and especially triglycerides). As healthcare providers we, doctors and scientists, are very much aware that the physiology-that is, the mechanism-of this wonderful sugar metabolism is one of many harmonies existent in the human body. While patients with diabetes seek help from us, our help is limited to what we have learned-and are still learning-from the human body. Thus, the medication we use today are not miracles, but rather a good example of understanding how one of the many mechanisms in body works.

Since the discovery of insulin in 1921, a hormone that is secreted from the pancreas and the only one to work at lowering the level of sugar in the body (several others increase the sugar level)-the development of treatments for diabetes has been focused on greatly in an effort to better serve humankind. Such developments include tiny, sharp needles and pens to deliver the insulin-known as insulin pens. Currently many alternative insulin delivery methods have been developed-via the skin or lungs-yet none of these are as successful as the human body’s normal program for dealing with a rise in the sugar during stressful conditions and after meals. Despite the incredible efforts and impressive studies carried out on both animals and humans, not every method of diabetes management (treatment) is suitable for every individual. Each person is unique regarding the capacity of their pancreas to generate insulin.

In the United States, more than 20 million people have diabetes; however this number is well below the actual number of sufferers. Having enough insulin is not the solution to the problem, while resistance to the action of this hormone can limit its efficacy leaving the glucose (sugar) level high. This further suppresses the pancreas’ ability to provide insulin and the remaining glucose becomes toxic to many vital organs, causing several of the following conditions:

• Heart (heart attack)

• Liver (fatty liver)

• Brain (stroke)

• Vessels (hardening of the arteries)

• Blood (easy clotting)

• Feet (gangrene and amputation)

• Immune system (suppression of the immune system, in turn leading to a tendency to infections, giving the opportunity of germs to invade various parts of the body; in the same way increase of tuberculosis bacteria, yeast infections, pneumonia)

• Skin (late healing after abrasions or trauma)

Excess sugar is converted into cholesterol which will further accelerate the detrimental effects to the vital organs (brain, heart, kidney).

Current suggestions for the management of the problem with sugar are education, better diets, correct and regular exercise, correct medication and careful follow-up. We know that God created cures for every illness. Respecting and thinking of this will encourage many of us to concentrate on solving the problem of diabetes. Prophet Muhammad, peace be upon him, indicates “Eat and drink, but never waste” and “Leave the food table before you are full.” The diet that is recommended for people with diabetes is to eat small amounts of food during the 3 main meals and to add 3 snacks to control the undesirable rise in sugar that occurs after eating a large amount. We are informed that we are full due to the induction of tension receptors in the stomach after the meal, the induction of the brain, and the digestion of food that leads to an increase in the level of sugar in the blood stream… etc. Unfortunately, most diabetics wait for the third mechanism to operate before leaving the table; as a result, they may continue to eat and further increase their blood sugar level, and this may in turn be the reason for early or late complications in diabetes.

Today, the greatest number of diabetics per population are the Pima Indians living in Arizona. Interestingly, a new molecule that has recently been developed seems to have a preventive efficacy for the development of diabetes and to assist in its satisfactory management, even after the diagnosis of diabetes. This molecule was actually found to be present in the saliva of Gila Monster again that is fairly close to the area where these affected tribes live.

Kelly J. Smith is a clinical diabetes research scientist in Arizona.