How Octopuses Are Able to Taste by Touching

Giesen et al.Molecular Basis of Chemotactile Sensation in Octopus. Cell, October 2020.

Octopuses have often captured human interest with the ability to use their eight suction-cup covered tentacles for touch and taste. Scientists have wondered for decades how their appendages work but very few have studied what happens on a molecular level. In a new report, researchers got a glimpse into how the nervous system in an octopus’ tentacles manage these functions. They identified a novel family of sensors in the first layer of cells inside the suction cups that have adapted to react and detect molecules that do not dissolve well in water. The chemotactile receptors on these sensory cells use those molecules to help the animal figure out what it is touching and whether or not that object is prey. This allows an octopus to distinguish between a rock versus a tasty crab. The underlying mechanism is that there are two types of sensory cells in the suckers that line their tentacles: mechanosensory cells for touch and chemosensory cells for taste.  Both taste- and touch-oriented cells are critical for helping octopuses to decide when to hunt and when to retreat. It is well known that particles on land easily travel through the air before they might be sniffed by a bear or a wolf’s nostrils. However, the process of smelling or tasting is much less clear in cephalopods that live in the ocean. Some chemicals can travel far from their underwater source and thus make it possible for some creatures to catch a smell of their prey from afar. But for chemicals that don’t move through the ocean easily, a touch-taste strategy can be useful for marine animals, including octopuses. While people tend to perceive five basic tastes – sweet, bitter, sour, salty and umami (meaty) – octopuses experience the world of taste differently. Instead, scientists found the most success by stimulating octopuses to respond to what are called terpenoid molecules, a secretion that is often released by marine invertebrates that functions as a defense or warning signal. They smell these molecules and can, in a way, smell fear in their prey.

Natural Forest Regrowth May Be the Best Method to Combat Climate Change

Cook-Patton et al. Mapping carbon accumulation potential from global natural forest regrowth. Nature, September 2020.

Reforestation has been considered the leading strategy in the fight to mitigate the effects of climate change with previous studies highlighting the role it can play in capturing and storing atmospheric carbon. There are many ways to incorporate trees into our landscapes, however one of the cheapest and easiest options is to allow forests to regrow on their own if conditions can permit them to. Now, a new study has mapped the potential carbon accumulation in naturally regrown forests over the next 30 years. Researchers from 18 countries brought together more than 13,000 georeferenced measurements of carbon accumulation to generate a wall-to-wall, one-kilometer-resolution map spanning 43 countries that highlights areas with the greatest carbon returns if trees were allowed to reforest naturally. The team demonstrated that natural forest regrowth can capture up to 23 percent of global carbon dioxide (CO²) emissions from the atmosphere every year. This is on top of the carbon sequestration already provided by existing forests, which absorb around 30 percent of annual CO² emissions. The biggest advantage of natural restoration of forests is that it often requires nothing more than human inaction. Nature is constantly at work doing its duty to restore forests often unseen on the edges of fields, on abandoned pastures, and wherever forests lie degraded or former forest land is abandoned. Moreover, natural forest regrowth may promote the re-establishment of local tree species that are best equipped to survive in a given location and support the many organisms that eat them or dwell amongst their branches and roots.

However, natural regrowth may not always be the answer. For example, at sites that are highly degraded, or seed sources are far away, actively planting trees can help to start or speed recovery while helping to establish the right species mix for current and future conditions. While planting trees can sometimes be necessary it should usually be the last option since it is one of the most expensive and often least successful methods of combating climate change. It is estimated that humanity should collectively plant about a trillion trees over the next three decades to effectively fight climate change, which averages out to about a thousand new trees planted in the ground every second and assumes that every tree survives and grows in a healthy manner. Once the cost of nurseries, soil preparation, seeding, and thinning are accounted for, it would easily cost hundreds of billions of dollars. If natural forest growth is cheaper and better then why not work to protect the existing trees and let forests to grow on their own?

Li et al. Innate connectivity patterns drive the development of the visual word form area. Scientific Reports, October 2020

A new study suggests that humans are born with a part of the brain that is prewired to be receptive to seeing words and letters. Researchers analyzed brain fMRI scans of 40 newborns and found that the “visual word form area” (VWFA) was already connected to the language network of the brain, which is akin to the scans of 40 adults. These findings are quite surprising considering some researchers had hypothesized that the pre-reading VWFA starts out like any other part of the visual cortex that are sensitive to seeing faces, scenes, or other objects and only becomes selective to words and letters as children learn to read or at least as they learn language. However, a new study shows that even at birth, the VWFA is more functionally connected to the language network of the brain than it is to other areas. It is likely that experience with spoken and written language will strengthen connections with specific aspects of the language circuit and further differentiate this region’s function from its neighbors as a person gains literacy. The main goal of this study is to learn how the brain becomes a “reading brain” and to help understand the differences in reading behavior, which could become useful in the study of dyslexia and other developmental disorders.

Ebru, the art of crafting images and pictures with special paints on the surface of water, originated on the continent of Asia, spread to Anatolia, and from there to the rest of the world. Ebru has long been the name given to the original Turkish art of “paper marbling” [1].

Enchanted by their interaction with water, human beings started practicing the art of paper marbling. By practicing Ebru, one may interpret the time on the marbling tray as a sort of time travel in which the wiggles of the water take a journey between the past and the future.

For ages, people have been using long-lasting rock surfaces to transfer information to future generations. These artworks and writings are reminders of past civilizations and they have always gained the attention of mankind around the world.

Some natural ingredients for traditional Ebru art include rose branches, dust paint, bile juice, and gum from a wild licorice plant. This natural combination of each ingredient of Ebru art ensures its uniqueness.

Each careful sprinkle of a color on the surface of the water is the reflection of the emotions that are felt by the artist yet are difficult to express otherwise.

Ebru is a delicate reflection of a civilization in which water is exalted as glorious and precious. It is one of the major elements of our world, that are essential for existence, along with soil, air, and fire. Ebru is the art of enthusiasm presented with sincere feelings.

Ebru gives a new perspective to the world of art and to cultures that are not familiar with it, since the concept of water serving as a base might initially seem impossible.  Throughout history, eastern and western civilizations were established around sources of water. Water in fact attracts human beings to its vibrancy like a magnet. It is the source of life for all the people from different ethnic groups, colors, languages, and religions. The mosaic appearance of Ebru art reflects human diversity in its tank with harmony and coherence [2].

In the past, people used to write thing they didn’t want to remember on water. Anything is doomed to disappear on the surface of water other than Ebru.

Using water as a medium is paradoxical because water signifies change as opposed to permanence. However, embroidery on the surface of the water is not something to be planned beforehand but rather an art form that the Ebru performer comes up with at the moment. A single stroke can be transformed but not reversed.

Once the artist has reflected his or her soul’s shape, and the colors have taken their place, the paper is gently laid on the water.

Ebru is like life itself; even if we think we do the same things every day, every moment differs from the others and is unique in its own way.

Ebru is either in the sky or on the Earth [3];

“O eye, do not sprinkle tears into my heart’s fierce fire, for there will be no way you can put out such a fire.
Is the revolving sky’s color the color of water? Or is it my tears that cover up the sky, I cannot know.”

Those who are interested in the art of Ebru and put their hearts into it will connect with a feeling of spiritual serenity and tranquility. Life in contemporary times is a never-ending wave of turmoil. Those who want to escape the hustle of the routines of life will never be rejected and will be welcomed to the ambiance of serenity by the peaceful waves of Ebru.

It takes people from their own world and brings them to another world of imagination where they can reflect on their feelings and get rid of the negative emotions within them.

For those who are stuck in the modern cycle of never-ending tasks, it is a way for them to reach a peaceful state of mind and relax.

Ebru art might take the artist back to their childhood when they used to play with dirt and mud. Perhaps the lack of preserving their childhood feelings can be remedied.

Ebru craftsmen use the biz, a tool used like a pencil to write on the surface of the water. In Ebru, every move on the water gives color patterns.

The art of Ebru in such a small container can take a human to anywhere that they wish to be or can be a canvas for any image that they wish for, such as a garden of flowers or a limitless sky. It will be anywhere other than any negative emotions inside.

Ebru art eventually makes the performer, as well as those that enjoy it, joyful once it is placed onto the wall of a house or at work and is thus able to begin emanating its bliss.

* This article was based on the speech given by Mualla Yazici in the Fountain Talks meeting at Fishers Public Library, Indiana.

References

1. Saracoğlu M. “Ebru or Water Marbling.” The Fountain 72 / November-December 2009.
2. Refik İ. “Uçsuz Bucaksız Bir Okyanusta Renklerin Dansı: Ebru.” Yağmur 3 Nisan, Mayıs, Haziran.1999.
3. “Su Kasidesi – Altın Nefesler,” Yeni Ümit Ekim, Kasım Aralık 1998.

Truffles are potato-shaped underground mushrooms that grow in all kinds of different environments ranging from high-rise forests of pine, oak, linden, fir and wild hazelnut to scrubs, under bushes, and in steppes and deserts. They maintain a symbiotic relationship by attaching to the roots of certain herbaceous plants and have a unique aroma with a sharp odor. Some cultures nickname truffles as bingos or buckthorns. There is also the belief that the mushrooms sprout faster under lightning or thunder thus earning them the nickname “daughters of thunder.”

Symbiotic association between truffles and plants

Nature thrives in a harmony that is based upon assistance and solidarity. Truffles have a special place in this harmony. For example, as plant seeds germinate and begin to grow into roots, the hyphae of truffles wrap around the plant roots, just like a glove does around fingers, and help the emergence of a special structure called “mycorrhiza” which facilitates food exchange between truffles and plants. Approximately 90% of plants coexist with different types of mushrooms, and some plants even need truffles to survive. Unable to photosynthesize, truffles need plants for organic nutrients, and plants need truffles, especially for the intake of more water and minerals from barren and arid soil.

It is estimated that the mushroom hyphae can be as long as 1 km in the forest soil is estimated to be more than 1 km. Truffles help to increase the contact surface of the tree roots with the soil hundreds of times while ingesting the water and minerals from remote areas where plant roots cannot reach. In this way, as soon as a drop of rain falls on the soil, it is relayed to the benefit of plants with hyphae that are invisibly thin and kilometers long. If this partnership did not exist between truffles and plants then the giant trees that we see in forests would not be able to grow tall enough and would possibly remain as bushes due to a lack of water and minerals from the soil.

Truffles and wildlife

A similar relationship exists between truffles and animals in the forest. Since they are generally active at night and cannot benefit from sunlight sufficiently, wild animals meet their vitamin D needs especially from truffles, an important food source. Recent studies show that some wild animal species survive solely on truffles. A large number of mice, squirrels, bears, deer, rabbits, hedgehogs, and bird species in the US eat truffles along with some monkeys, kangaroos, and bird species in Australia.

While the toadstools in the open can spread their billions of spores to the environment, the spores of underground mushrooms remain confined in their tissues. It is thanks to animals that can spot and extract the mushrooms that these spores spread from their tissues into the rest of the environment. Wild animals can locate, dig up, and eat underground truffles due to the strong and attractive aroma of the mushrooms. On the other hand, the spores that are expelled from the animals’ digestive systems lead to the production of fresh hyphae to partner with new plants via germination. This allows underground mushrooms to have the opportunity to sustain their generation and expand their natural habitat.

The conservation of animal species that face extinction also depends on the preservation of the variety of truffle species. From this point of view, truffles in the natural habitats are the sustenance of wild animals. Bediuzzaman Said Nursi (d. 1960), a renown Turkish religious scholar, said: “Our share is in vineyards and gardens. God Almighty allocated our sustenance there. These wild fruits are the sustenance for the wild animals. We should not touch their portion.” It is also known that Bediuzzaman discouraged his students who came across plenty of apple and pear trees on the mountains from eating those fruits. This approach also sums up a guiding insight about sustainable forestry and ecosystem.

Nutritional value and medical benefits

Truffles are richer in protein and minerals than other mushrooms. Their nutritional value consists of 53-76% water, 9% protein, 7% carbohydrates, and 8% minerals. Although they have high nutritional value, the most important feature making truffles superior to other mushrooms is their distinctive aromatic compounds. Due to their unique aroma, truffles attract the attention of many gourmets. It is no surprise that truffles have an exceptional place in exclusive cuisines.

Since ancient times, the medical benefits of truffles have been frequently reported. For example, Ibn Sina (Avicenna) is known to have recommended truffles for healing weakness, nausea, pain, and wounds.

Prophet Muhammad, peace be upon him, said, “Truffle is a sustenance like manna. Its sap is also a cure for the eyes.”

The belief in the nutritional value of truffles is also common in the Christian world. Between 827 and 844, Pope Gregory IV had advised the consumption of truffles to gain strength in battles.

Current studies have found that truffles contain several compounds that are essential for human health. A study published in 2016 is an important step for chronicling the fact that the extract obtained from truffle mushrooms proved to be useful in healing eye infections.

Economic value

The number of commercial-value truffles collected from natural habitats constantly decreases worldwide: it has dropped from 2000 tons in 1884 to 100 tons in 1990. Today, it is around 40 tons. The main factors of this decline are the destruction of oak forests, climate change, environmental pollution, global warming, and uncontrolled picking.

Despite the dramatic decrease in the number of truffles collected from natural habitats, they are sold between $250 and $4,000 per kilo depending on the type and quality.

Growing truffles

Under current conditions, truffles have to be grown by special means. People must grow the types of truffles that they wish to consume.

The first idea for the production of truffles came from a French farmer named Joseph Talon. At the beginning of the 19th century, Talon planted fresh seeds in the oak patches where truffles grew naturally. The existing truffle hyphae in the soil infiltrated the roots of new oak saplings and led to an increase in the production of truffles in the natural habitat. In the following years, Talon created new truffle production areas by planting the saplings he had already produced in other patches. Talon’s method is still used today.

In the 1960s, a period when there was a great decrease in the production of truffles in natural habitats, studies were conducted to find new methods. The methods developed by French and Italian scientists in the 1970s led to a massive success in truffle production. Truffle spores were inoculated at the root of oak saplings and plants were grown in greenhouses to develop only the desired truffle mycorrhizal system in tree roots. Having ensured that mycorrhiza had settled in the roots, the first truffle began to be harvested four or five years after planting the oak saplings in open areas. These methods have allowed truffle production in countries such as Australia, the USA, and New Zealand where truffles are not grown naturally.

Commercial truffle types

It is estimated that there are about 10,000 different types of truffles in the world with different sizes, colors, structures, and aromas. These mushrooms, which are now listed in restaurant menus and stocked on the shelves of luxury food suppliers, are only some of the truffles numbered in thousands.

Some of the commercial types are listed below:

Tuber magnatum: Known as the white truffle of Italy, it grows in the Alba region as attached on the roots of oak, hornbeam, pine and poplar trees. It is different from all species by its peculiarly pungent aroma. It is known as the most expensive food in the world because it grows in a very limited area and cannot be grown as a cultivated mushroom.

Tuber melanosporum: Known as the winter black truffle, it grows during winter by attaching to the roots of oak, hazelnut, and pine trees in Italy, France, Spain, and the Balkans. It has a distinctive aroma and has a wider growth area as compared to the white truffle. It is the most cultivated type of truffle in different continents of the world.

Tuber aestivum: Known as the summer black truffle, it grows by attaching to the roots of oak, nut, and pine trees in a wide geography spanning from Portugal to Azerbaijan, Morocco to Poland, and Sweden to Afghanistan. It bears lower economic value because it is widely grown and has an easily extracted culture and a lower-density aroma.

Terfezia claveryi: It grows in the spring across steppes and deserts by attaching onto the roots of herbaceous plant species belonging to the genus Helianthemum. It has a unique aroma and has a huge market in the Arab countries. Its culture has started to be extracted in recent years.

Oregon truffle: It grows in winter as attached on the roots of fir trees in Oregon, Washington, and Vancouver. It has white and black types. It has an important market in the U.S despite not being as valuable as the black and white species found in Europe. No results have been obtained from cultural studies yet.

Harvest of truffle

Picking truffles is like picking apples from a tree with the difference that truffles are collected from the root of the tree. It is difficult to understand whether the truffle underground has ripened or not. If the extracted truffle is not ripe enough then its economic value immediately suffers. That is why special dogs are bred to locate truffles. Sensitive to the truffle aroma, these dogs lead their owners by simply pointing out to the places where ripe truffles are found. These dogs are motivated by rewards and are encouraged with better rewards for finding higher quality, larger, and more ripe truffles.

References

• Alhussaini S.M., Saadabi A.M., Hashim K., Al-Ghanayem A.A. (2016). Efficacy of the Desert Truffle Terfezia claveryi to Cure Trachoma Disease with Special Emphasis on Its Antibacterial Bioactivity, Trends in Medical Research, doi: 10.3923/tmr.2016.28.342016, Volume: 11, Issue: 1, pp. 28–34.
• Bukhari, 5708; Muslim, 2049; Abu Dawood, Tibb, 12; Ibn Majah, Tibb, 8.
• Hall I.R., Brown G., Zambonelli A. (2008). Taming the Truffle: The History, Lore, and Science of the Ultimate Mushroom, Timber Press.
• Sahiner Necmeddin, Son Sahitler, Istanbul: Nesil Yayinlari, 2011, Volume 1, pp. 113.
• Trappe M, Claridge AW (2010). “The Hidden Life of Truffles”. Scientific American. April 2010: 78–84.
• Wedén C. (2008). Tryffel. Infotain &Infobooks Sweden AB, Stockholm.

Organic substances in the soil go through oxidative decomposition depending on factors such as temperature, air, humidity, and pH balance. This is a slow burning (oxidation) event of organic substances. However, oxidative decay is hindered if one of the aforementioned factors is lacking. Then, a slow decay of organic materials in soil called humification takes place.

Humification occurs in an open system in contact with air. For example, early chemical processes start with leaves changing color in autumn. The break down and partial ingestion of leaves by soil organisms follows. During this time, water soluble carbohydrates and proteins leave the leaf tissue. What remains behind are plant structures like cellulose and lignin, which are not broken down yet. Since leaf shapes are not completely deformed, species identification can still be possible at this stage. In the decay step, however, the cellulose and lignin are decomposed by various fungi species and converted to humus.

Humic substances and their properties

Humic substances are intermediate products that occur as the result of organic materials going through a series of chemical reactions. These intermediate products are humic acid, fulvic acid, and humate. Their molecular weights are around 1.000-10.000 gr/mol, 10.000-100.000 gr/mol, and 100.000-10.000.000 gr/mol, respectively. Humic acids contain weak aliphatic (carbon chains) and aromatic (carbon rings) organic acids that are soluble in water when it has a base medium but insoluble under acidic conditions.

Fulvic acids with smaller size molecular structures can reach plant roots, branches, and leaves easily because they are soluble in water under all pH conditions (acidic, neutral, and basic). Thus, trace elements such as iron, zinc, copper, manganese, and boron can be easily transported to plant tissues via fulvic acid.

Humates, however, are insoluble in water. Only the portion of a humate called ulmic acid can dissolve in alcohol.

Major functions have been assigned to humic matter in the nutrient and carbon cycle, as they are inseparable members of the ecosystem. Plants capture significantly more nutrients from humic matter than from clay minerals. Even though they can be depleted from soil by certain agricultural practices in less than 50 years, they can still remain in natural soils, outside human activity, for hundreds or even thousands of years without being degraded. This very long presence in soil enables them to continue their functions longer. According to radiocarbon dating, humates can last approximately 1140 years; and humic acid and fulvic acid last for 1235 and 870 years, respectively, in natural soils.

Positively charged nutritious elements (cations) remain in the soil by binding to negatively charged (anions) in humic matter. Because this bond is weak, useful elements for the plant can easily be exchanged with another cation, becoming free and getting absorbed by the plant. On the other side, cations such as iron, copper, zinc, magnesium, manganese, and calcium, which are hazardous to plants when taken excessively, are held in the soil, bound to humic matter and thus not causing toxicity.

Another significant feature of humic and fulvic acid is their ability to form water bridges. Water bridges facilitate the movement of nutrient ions towards roots via soil solutions.

Aside from agriculture, humic matter, with its aforementioned properties, serve humankind in the industrial, environmental, and biomedical fields.

Industrial and environmental applications

Humic matter is utilized in the staining of leather works, as wood lining paint (natural blue color), as well as water based stripping material for furniture stains. Humic matter is also used in the production of durable, resistant papers in the paper industry, to provide mechanical strength to processed ceramics, and as an additive. It is also applied as a coloring, hardening, and plasticizing agent in plastic fabrication.

Humic and fulvic acids gain significance regarding their ability to form water soluble substances with many metal compounds containing radioactive elements in their structure.

In environmental chemistry, the main role of the humic matter is to remove toxic substances, human sourced organic chemical matter, and other pollutants from water. Calcium humate, obtained from humic matter, can bind and remove nickel, iron, cadmium, and copper in addition to radioactive elements produced at nuclear power plants from water.

Humus based filters are designed to treat sewage water and mud waste. Oils, stains, poisonous phenolic substances, and pesticides are removed from sewage via these materials. In poultry, humic substances are employed to absorb and eliminate the odor of waste gases.

Biomedical applications

Drugs for the treatment of human and animal diseases are developed from humic matter. These can be used for the treatment of viral and bacterial illnesses, in the prevention of blood clots, to cure infections, and to remedy estrogen deficiencies. Clinical studies have shown that common viral diseases of children’s respiratory tracks can be treated with fulvic acid supplements. A lot of medical research has shown that humic matter, especially fulvic acids, have the ability to provide protection against cancer causing viruses. In a study, laboratory mice were given ethanol to trigger gastritis and it was determined that humic acids supplied to mice led to a significant reduction in the harm gastritis caused. The fact that humic acids can form compounds with heavy metals, such as cadmium, enables the excretion of heavy metals from organisms.

In our universe there is no place for waste. Once every particle completes its task, it is returned in a different fashion to be assigned another job. Humification is a good example to this reassignment as a complex recycling event in the soil. It is amazing to observe everything being generated from one thing and everything converted into one thing so easily and in such a crafty, balanced, and organized fashion. In fact, the power and wisdom behind the conversion of the remains of millions of different organisms into a few similar substances to be employed in different tasks are no less amazing.

Distribution and density of the hairs in our body is coded in our genes. This program is activated after birth and hair roots are formed at around 8th-10th week of pregnancy. The hairs that cover the fetus are thin, short, and weak. The growth of hairs is completed in the 22nd week. Number of hairs in a fetus does not change much according to gender. Later on in a person’s life, hairs can become dense or rare, owing to factors such as race, age, gender and hormonal state. There are hair roots covering almost all over our body except for the soles, palms, forehead, the areas under the eyes, on and behind the ears.

A hair is made up of the hair root and the hair shaft on it. A hair root is surrounded with two layers. The duty of these layers is to prevent harm to the hair shaft and let the hair grow in the right direction. A hair root is a multilayered structure where every layer has a different function. The papilla is in the base of the hair root and it basically serves to send nourishment to hair cells. The upper layer of the hair shaft is the hard substance called keratin. The innermost layer, which can be seen as the spinal cord of a hair, does not exist in every hair shaft. The second layer, known as the cortex, constitutes most of the hair shaft. The color of hair is mostly determined by the pigment in this layer. The outermost layer is the upper skin of the hair.

Hairs in different parts of the body have their peculiar forms of and limits to growing. Under the control of hormones, hair roots cause hairs of different properties—such as thickness and color—to form. The hairs in moustache, armpits, between the legs, beard, and on the head grow fast and continually. On the other hand, the hairs on our arms, chest, back, legs and including those in the eyebrows grow very slowly and they know their limits. If the person does not own functional testicles, there may be no hair in certain areas of the body except for the hair on his head.

Most of us are apt to think that certain stories make our hair curl; actually, hair erector muscles are the unsung heroes of those stories. Under every hair in the body, there is an erector muscle that makes it move. These muscles have important functions for the body.

Firstly, it helps the oil glands carry out their function. The oil sacks are located on the surface of a hair. The sizes of these sacks are around 0.2-2 millimeters. Sacks are in the form of clusters. Oil glands are also placed all over the body, accept for the soles and palms. They are the natural “lubricants” for the skin and hairs; they protect the skin from the damage of drying up. Every gland under the skin has a channel. There are alveoli that open to every channel. When the hair muscle is stimulated, the hairs become erect and the connected gland start secreting a substance called sebum. The glands empty their contents to the body of the hair.

Regulating the acidity (pH) level of the skin is among the duties of the hair erector muscle and it produces a protective gel. The oily secretion forms a thin layer of gel; as it serves protecting the skin from heat and cold, it is given an antibacterial effect as well. The natural coating of the skin prevents reproduction of harmful germs. The pH level of the skin is 5-6 and it does not allow bacteria to grow. If this substance is not secreted from the skin, the pH acidity shifts toward alkali, moisture level of the skin increases; the fat layer and then the natural coating is damaged. Thus, germs find a suitable environment to reproduce.

Hair erector muscles are also given a role in adjusting body heat. The hairs in the human body are not related to heat isolation. When the body is exposed to cold environments, the mechanisms that increase body heat are activated. When sympathetic nervous system stimulates hair erector muscles, they contract, hairs bristle, and the body heat is tampered through the reduced heat release. Sometimes, even the invisibly small hairs erect and goose bumps appear on the skin. The purpose is to form a screen for heat. They also allow for perspiration in hot weather and help the body to cool down. In addition, hair erector muscles serve as touching receptors as well. The receptors in hairs easily detect objects on the body surface. Hairs that are activated by touch stimulate the nerve tissue in their base. In a way, they keep a round the clock watch for the body; as tiny and unsung heroes.

They say that perfection is hidden in details, which is also very true for hairs. And perhaps, the secret to appreciation lies in recognizing details, and appreciating their perfection.

Every human being asks the question “why,” though at different levels, to explain the unexplained. It follows a pattern of questions, like “Why did the financial crisis in the U.S. happen in August 2008?” “Why did the space shuttle Challenger explode?” “Why did the terrorists commit the September 11 attacks?” In statistical terms, such unexpected events are named “outliers,” however, they are part of the system and among the components constituting the overall system’s complex behavior. Thus, they need to be part of the explanation in order for the explanation to be complete. We are naturally tempted to come up with universal explanations of the complexity behind these major events so that we can be ready when a similar thing happens again. Though simple mathematical equations or relationships relate to us better and provide a universal explanation, they are typically practical only when the outliers are excluded from the system behavior. Statistics help us greatly in quantifying and characterizing the outliers, especially in the form of probabilistic expressions, such as “there is a 30% chance of a hurricane next week.”

Understanding the complexity around us involves the development of a model that is simple enough for us to comprehend but yet universal enough to capture most of the dynamics of the complexity. The simpler and the more universal the model, the more powerful it is. The universality of a model, however, is hindered by the potential inability to capture something unexpected. The tradeoff between simplicity and universality exists in all modeling efforts; and the models finding the delicate balance in this tradeoff are the most effective ones. A simple mathematical relationship known as “the power law” has been used extensively to characterize and model various natural and social phenomena.

What is the Power Law?

The “power law” does not refer to a misconception that “whoever has power will rule,” but rather it refers to a particular way of characterizing dependency between two quantities. When the number or frequency of an object or event varies as a power of some attribute of that object (e.g., its size), the number or frequency is said to follow a power law. In more general terms, there exists a power law relationship between x and y if y is growing or reducing polynomially when x is growing linearly (y _͌ x^–α). Mathematically speaking, this means that the relationship between y and x is mainly characterized by the exponent -a. An exponent is simply shorthand for multiplying that number of identical factors. So, 4³ is the same as 4x4x4; that is three identical factors of 4. As shown in Figure 1, a quantity with an exponent has three components: the base, the exponent, and the coefficient. So, for 4³, the base is 4, the exponent is 3, and the coefficient is an implicit 1.

Figure 1: Description of an exponent in a power law relationship.

Figure 2: Sample power law relationships between x and y, where y = x^–α.

The power law relationships are traditionally expressed with a negative exponent, which simply means the inverse of the quantity. That is, y _͌ x^–α is equivalent to y _͌ 1/x^α. For example, when a is 2, y will reduce from 1/4 (i.e. 0.25) to 1/9 (i.e. ~0.11) if x grows from 2 to 3. Likewise, when a is 0.5, y will reduce from 1/2 (i.e. 0.5) to 1/3 (i.e. 0.33) if x grows from 4 to 9. For those who enjoy graphs, Figure 2 illustrates these mathematical relationships in linear and logarithmic scales.

Power law on different scales: Atoms to planets

To start with, gravitation, acoustics, electrostatics, and light and electromagnetic radiation, all exhibit a form of power law in that physical quantity or strength that is inversely proportional to the square of the distance, which corresponds to a power exponent of 2. [1] Gravitational force between two particles, the electrostatic force of attraction between two electrically charged particles, the intensity of sound signals coming from a source, and finally the intensity of light or electromagnetic field coming from a source all follow a power law with respect to the distance.

What makes the power law relationships more interesting is their independence from scale or size of the measures being related to each other. This is why we sometimes call power law relationships as “scale-free” relationships or “scale-invariance.” For example, the gravitational force between two spherical particles decays with a power exponent of 2 regardless of the sizes of the particles though the actual force is certainly dependent on the particle sizes. So, the particles can be at nano scales (e.g. a group of atoms) or macro scales (e.g. a planet), but the relationship stays the same!

Power law in frequency: Wealth, terror, and earthquakes

A common usage of power law relationships has been to model and understand frequency of a varying measure. A power law typically very well represents the distribution of wealth in a society. [2] According to a recent study, the distribution of wealth in China during the years 2003–2005 follows a power law with an exponent ranging from 1.758 to 2.285. If we consider an average exponent of 2 for Chinese wealth distribution, this means that if there are 1 million Chinese people who owned $1000 there were 1000 that owned $1M. Thus, the power law essentially expresses how skewed the distribution of a frequency is (see Figure 2). The larger the power exponent, the more skewed the distribution. In this case, a larger power exponent means a more imbalanced wealth distribution while a power exponent of 1 refers to an evenly distributed wealth.

Many other social patterns exhibit power law. A recent study showed that it exists even in terror events! The number of casualties per insurgent event and the number of insurgent events per day follow a power law. [3] Historical data for the last two centuries show further that the number of casualties per war or a terror attack follows a power law distribution. What is even more interesting is that the number of casualties and the number of attacks within an insurgent conflict both follow power law. That is, when only a particular conflict between two countries or ethnic groups is considered, the number of casualties per insurgent event and the number of insurgent events per day follow the power law. This suggests a “self-similar” pattern. Likewise, traffic measurements for many systems show power law distributions of size. For instance, if one observes the data traffic on an Internet connection and counts the number of bytes being transmitted per hour over that connection, a power law distribution of the count of bytes will emerge. Further, if this counting is done per minute instead of per hour, a similar distribution will still emerge – again showing a self-similar pattern. [4]

The power law has been observed in several natural phenomena as well. The frequency of earthquake magnitudes follows a power law. [5] This refers to the intuitive notion that the number of earthquakes with small magnitudes (which humans do not even feel) is much larger than the number of earthquakes with large magnitudes, (which can kill many humans). Small earthquakes are the norm while large ones the outliers. However, without the outliers, there is no power law distribution! Thus, the power law distribution of a quantity comes with an interesting observation: If a quantity is indeed following a power law distribution, then the likelihood of an outlier event increases as the time goes by without an outlier event. This is why geoscientists would make comments like “The region X is due for a major earthquake!” indicating that the region X has not been receiving a major earthquake (i.e. an outlier) for several years. The issue, though, is determining the threshold for an outlier is typically ambiguous and may require many years of measurements and data, which may be impractical.

Power law in growth: Rich get richer

Growth of systems also exhibit power law in various ways. Social growth follows power law due to the well-known “rich get richer” rule, which refers to the intuition that “important” people in the society attract more of the attention of newcomers. This dynamic situation is observed, for example, in the growth of the Internet. Several studies [6] showed that the connections between Internet Service Providers (ISPs) (e.g., AOL, Yahoo!, AT&T, Sprint) follow a power law distribution in that the number of connections per ISP (which shows how well an ISP is connected to the rest of the world) is represented by power law. In other words, there are few ISPs with many connections to other ISPs while most ISPs have a few connections to the others. This is believed to be due to the “rich get richer” rule since an existing ISP with many connections is more likely to gain the business of a new ISP who is joining to the Internet. So, it is somewhat an economic pattern too.

If economics (or the money) is taken out of the picture, social growth still exhibits power law. Online social networks such as Facebook, LinkedIn, and Flickr are clearly following a power law distribution. It is found that the power exponents are in the range of 2.5 to 3.7, indicating a highly imbalanced social growth pattern where few people are at the “center” of the social network with hundreds or thousands of friends, and many people have only one or two friends. [7] Again, the typical explanation for this growth pattern has been the “rich get richer” rule, but “richness” refers to the number of existing friends in this context rather than money.

Physical growth shows power law too in many ways. For instance, roughness of a growing surface as time goes by follows a power law distribution with an exponent ranging between 0 and 1 where an exponent of 0 refers to a smooth growth and 1 refers to a stiff growth. The surface roughness is measured by the variance of heights of surface locations. [8]

Does it really exist? Why does it exist?

Verifying existence of a power law distribution is not easy and requires enough number of samples to show the “tail” of the distribution. The tail of the distribution refers to the samples with large (or rare) values. For example, for the power law distributions in Figure 2, the portion of the distribution when x is greater than 10 (i.e. x>10) roughly corresponds to the “tail.” The tail corresponds to the rare samples. Though statistical theory calls those rare samples “outliers,” the distribution will not be a power law distribution without them. They are strictly parts of pieces that constitute a power law relationship, and observing them typically requires long periods or large numbers of measurements. Due to this difficulty, the existence of the power law is questioned for many real systems. Most of the time, claims of the existence of the power law typically come with an error factor indicating the confidence of the claim. The bottom-line is to observe trends in the samples and thus establish sufficient confidence (e.g., more than 95%) that the power law distribution does exist in the samples.

For those systems with clear exhibition of power law, the root causes of it have been of high interest. The “rich get richer” rule is intuitively one of the root causes, and it is intuitively a natural dynamic to get attracted by a rich member rather than a poor one. Growth certainly naturally follows the “rich get richer” rule, but we have system components slowing their growth, flattening, and then deteriorating. So, not everything is growing, and actually, we have as many things deteriorating as growing. For instance, participants join or leave the Internet or the social networks, and likewise, people join (i.e. birth) or leave (i.e. death) society. How does the power law stay in such systems then?

Due to the “rich get richer” intuition, the power law is considered to be the signature of “self-organization.” The fact that so many natural or synthetic systems are exhibiting this signature deserves the question: “Is it really self-organization?” Maintaining a global power law distribution for a system requires either (i) every member joining or leaving the system according to the “rich get richer” rule and having global knowledge of the whole system or (ii) somebody who knows everything about the system and gives explicit direct orders to each member when they are joining or leaving. Which one is more likely?

Murat Yuksel is an Assistant Professor at the CSE Department of The University of Nevada – Reno (UNR), Reno, NV.

References

[1] Wikipedia, “Inverse-square law,” http://en.wikipedia.org/wiki/Inverse-square_law

[2] M. A. Santos, R. Coelho, G. Hegyi, Z. Néda, and J. Ramasco. 2007. “Wealth distribution in modern and medieval societies,” The European Physical Journal, Volume 143, Number 1, pages 81-85.

[3] J. C. Bohorquez, S. Gourley, A. R. Dixon, M. Spagat, and N. F. Johnson. 2009. “Common ecology quantifies human insurgency,” Nature, Volume 462, December, pages 911-914.

[4] T. Karagiannis, M. Molle, and M. Faloutsos. 2004. “Long-Range Dependence: Ten Years of Internet Traffic Modeling,” IEEE Internet Computing, September/October, pages 57-64.

[5] T. Lay and T. Wallace. 1995. Modern Global Seismology, Academic Press, San Diego, CA.

[6] M. Faloutsos, P. Faloutsos, and C. Faloutsos. 1999. “On power-law relationships of the Internet topology,” ACM Computer Communication Review, Volume 29, Issue 4.

[7] R. Kumar, J. Novak, and A. Tomkins. 2006. “Structure and evolution of online social networks,” Proceedings of ACM SIGKDD, pages 611-617.

[8] A. L. Barabasi and H. E. Stanley. 1995. Fractal Concepts in Surface Growth, Cambridge University Press, Cambridge, England.

The twisted grammar of the naturalistic fallacy

In assuming nature to be uniquely real, a naturalist proposes that “reality” (or “existence”) means “natural being” and nothing more. Instead of saying, “nature is real,” (or “nature exists,”) a naturalist prefers to says, “reality (or existence) is nature.” Such an utterance has an odd syntax, with the subject and predicate being strangely exchanged, thus twisting the grammar and invalidating it. It is not vague, but rather nonsensical. Such nonsense originates from the awful mistake of reducing a group (here, “beings”) into a member (“natural beings”), or, to use logical terms, equating a universal (here, “reality” or “existence”) to a particular (“natural reality” or “natural existence”). What a naturalist attempts here is to narrow the meaning of reality; this can be called “naturalistic fallacy,” borrowing G. E. Moore’s phrase. It is with this attempt that naturalism becomes unreasonable. Namely, as it is reasonable to conceive of “unnatural” beings, that is, any entities outside the world observed, it is thus unreasonable to assume nature as being unique in reality. In other words, the “world observed” is not equal to (nor does it consume the meaning of) the world of reality. The phrase “natural existence” is a necessary reference to-at least the possibility of-“unnatural existence.” Indeed, against this immediate inquiry of justification, naturalistic discourse does nothing but recede from a logical base. As the famous naturalist Kai Nielsen states, naturalism is nothing but an idea without any idea of foundation. That is to say, naturalism remains as arbitrary as any fantastic speculations about an alien world, as both share the same status of justification.

Hetoric divorced from logic

(a) “Naturalism is the view that only natural objects, kinds, and properties are real.”

As “natural” here is used to mean “of the world observed,” then the use of “only” means that “real” cannot be the proper predicate for the sentence. This statement is odd. To perceive the oddity, imagine (if possible) a man who understands the concept of “color” but is unable to perceive anything except red objects. Had such man said, “Only red is a color,” this is then equal to “All color is red.” Similarly, a naturalist suggests imagining reality as “comprising” (not “including”) nature. Can you imagine yourself answering this question: “Do you know why birds are eagles?”

(b) “Naturalism is the belief that the world is a single system of things or events, every one of which is bound to every other in a network of relations and laws, and outside this natural order there is nothing.”

If one were to ask a naturalist what convinced them to view the world as a single system that excludes unnatural things, they would answer, “The fact that I haven’t seen such things.” Responding thus, they admit the possibility of unnatural realities, which fulfills the meaning of the phrase “outside this natural order” in the statement. If a child asks this naturalist what might happen outside the natural order, how meaningful it is if they reply: “I have no idea” and how meaningless if they reply: “Nothing.” Such a conversation would demonstrate that it is impossible to place nature into “space” as a concept of physics, and that it is certainly not a childish attempt to try to squeeze reality into nature.

Groundless denial of supernatural

(c) “Naturalists reject all such notions of spirits, disembodied souls, non-material personal gods, and more-than-natural agencies. The grounds for the rejection of these notions are a lack of evidence adequate to support these notions.”

Ideas of spirits or souls are referred to as “supernatural” in that they are “ordinarily” not subject to the world observed. This means that they might be subject to the world of phenomena or of experience. There may be (reportedly, are) many experiences regarding supernatural phenomena, like spirits, angels, inspirations, revelations, etc. If this is the case then it would be unreasonable to reject all the relevant human traditions. Just as a momentary sighting of a peculiar insect is sufficient reason for the conviction that there is such a species on earth, the same is true for more peculiar entities. This indicates, as William R. Dennes clearly puts, that naturalists may have no reason to exclude intelligible reference to supernatural. Had a child reported to a naturalist that he had certainly seen a ghost, or that his dead grandfather had related a secret to him in dream, but the naturalist denies the child’s claims, accusing him of lying or dreaming, then the child’s rejection, in turn, of all the stories told and all the advice given by the naturalist that are based on experience would be meaningful.

(d) “Naturalism denies that there are any supernatural or spiritual realities. There are no purely mental substances and there are no supernatural realities beyond nature or transcendent to the world or anything of the sort, or at least we have no sound reasons for believing that there are such realities or perhaps even that there can be such realities. Physical realities, or perhaps as well realities dependent on physical realities, are the only kind of realities there are.”

The problem in the above statement is that the non-existence of supernatural entities cannot be reasonably claimed, let alone proven. Common sense commands that we not deny any possibility unless logically necessary. In logic, the denial of possibility is one of the two greatest mistakes; the other is the refusal of necessity. It seems that a naturalist cannot maintain such mistakes forever as they would necessarily encounter some form of supernatural experience, just as other fellow humans are. In other words, conjectures die away whenever phenomena manifest themselves. A naturalist then cannot be serious in his materialistic position, in denying the most manifest supernatural phenomenon, the soul, the factual manifestation of which is consciousness and the conscience. Therefore, rejecting any “purely mental substance” is a sophistic proposition. The immutable duality of “subject” and “object” always warrants the fact that “soul” is the constant interference of the supernatural into natural. Namely, if “nature” is the object that is observed, “I” am the subject that observes. Here we infer that a naturalist can only pretend to become a materialist at the expense of their own self. As Schopenhauer once wrote, materialism is the philosophy of the “subject” that forgets to give account of himself.

A pointless appeal to natural science

(e) “Naturalism is the recognition that it is within science itself, and not in some prior philosophy, that reality is to be identified and described.”

If science is claimed, in this approach, to identify reality, that is, to assign by observation what is real and what is not, then science itself is at stake as the objective study of natural reality, merely because it is the concept of reality that justifies observation. Plainly speaking, it is the sense of “real” that qualifies observation, not the opposite. This is why it is meaningful to say, “What we observe is real.” It is impossible to identify anything without having a “prior” conception of reality. In Kant’s dictionary, it is a priori concepts, the most prior of which is “reality,” that ensure all a posteriori notions, which all scientific terms are subject to. Now, upon this logical structure it is meaningful for a child to ask: “Aren’t ghosts real?” as well as for a naturalist to reply: “Certainly, not!” Similarly, natural science asks: “How is natural reality?” and answers: “It is in accordance with observation.” Thus, science admits that the reality of nature needs to be identified by a prior philosophy, a metaphysical notion. This means that natural science normally denounces (scientists must denounce) the awful illusion of scientism, the claim that science is uniquely eligible to identify the reality of the world; it is in regard with this that Wittgenstein warns that “the whole modern conception of the world is founded on the illusion that the so-called laws of nature are the explanations of natural phenomena.” What the philosopher means is that a scientist is no wiser about nature than anyone else when he steps out of his laboratory.

A final word

One may gather from this brief analysis that naturalism, in its absolute form, is destined to struggle forever, if not pass away, with the irremovable fallacy of reductionism. A naturalist may understand that to avoid from this destiny they must abandon the vacuous attempt to “invent” a logic for the world, rather maintaining the language on the grammar of possibility when assuming metaphysics, by stating, for instance, “Nature may be autonomous; who knows?” Such normalization turns naturalism, as Kai Nielsen states, into a game that might be called “fallibilism” and must be played without any confidence or hope. As a result, for anybody who wants to take metaphysics seriously for their ultimate concerns, as Michael C. Rea emphasizes, there is no such an option as naturalism.

Erkan Mazhar Kurt has a PhD in theology. He is an executive member of The Institute of Interfaith Dialog, Houston, Texas.

Notes

1. See, William Ray Dennes, Some Dilemmas of Naturalism, Columbia University Press, New York 1960, p. 80.

2. Kai Nielsen, Naturalism without Foundations, Prometheus Books, New York 1996, p. 35.

3. See, Michael C. Rea, World without Design: The Ontological Consequences

of Naturalism, Clarendon Press, Oxford 2002, p. 56. (These and the following emphases are mine for attention at conceptual relations.)

4. See, ibid, p. 55.

5. Cf. Ludwig Wittgenstein, Tractatus Logico-Philosophicus (tr. D. F. Pears & B. F. McGuinness), Routledge & Kegan Paul, London 1961, p. 149.

6. Sterling P. Lamprecht, The Metaphysics of Naturalism, Meredith Publishing

Company, New York 1967, p. 209.

7. Dennes, ibid, p. 21.

8. Nielsen, ibid, p. 25.

9. Cf. Robert Sokolowski, Introduction to Phenomenology, Cambridge University Press, New York 2000, p. 14.

10. Cf. A. D. Smith, “Non-Reductive Physicalism?” in Objections to Physicalism

(ed. Howard Robinson), Oxford 1993, p. 225.

11. Cf. Ralph Walker, “Transcendental Arguments against Physicalism” in Objections to Physicalism (ed. Howard Robinson), Oxford 1993, p. 78.

12. Arthur Schopenhauer, The World as Will and Representation (tr. E. F. J. Payne), Massachusetts 1958, II, 313.

13. See, Rea, ibid, p. 42.

14. Cf. Dallas Willard, “Knowledge and Naturalism” in Naturalism: A Critical Analysis (ed. William Lane Craig & J. P. Moreland), Routledge, New York 2000, p. 30.

15. See, Immanuel Kant, Critique of Pure Reason (tr. J. M. D. Meiklejohn), Prometheus Books, Buffalo 1990, p. 7.

16. Wittgenstein, ibid, p. 143.

17. Cf. Ian G. Barbour, Religion and Science: Historical and Contemporary Issues, HarperSanFrancisco, New York 1997, p. 87.

18. Nielsen, ibid, p. 26.

19. Rea, ibid, p. 59.

The words khalq (creation) and khuluq (nature) are derived from the same root word. Khalq relates to the external form or appearance, the visible, material, and experienced dimension of existence; khuluq is concerned with the spiritual dimension, meaning, or content. An individual cannot be judged or known by his or her outer appearance, for one’s real identity lies in one’s character, temperament, and natural disposition. However many different images one may project; one’s true character or temperament eventually will reveal itself. How meaningful are the following words of an Arab poet of the pre-Islamic Age of Ignorance:

If a man has a bad quality, sooner or later it will reveal itself;

Let him continue to think that it can remain hidden.

In other words, the outer appearance is deceiving, for one’s natural disposition removes or corrects all deceptions and thereby reveals one’s true nature. Since one may acquire a second nature through education and habituation, moralists divide nature into good and bad. In the present context, we use “nature” to mean “good nature.”

The most correct standard of a good spiritual life, one that Sufism uses to describe or qualify a person, is good nature. One who has taken a few steps forward in good nature may be regarded as advanced in the spiritual life. Although miracles, dazzling stations, and superhuman actions may be acceptable when they issue from good nature, they are worthless if not combined with good nature.

When asked which believer was better on account of his or her belief, the Prophet Muhammad, upon him be peace and blessings, answered: “The one who is better in conduct or nature.” This is natural, because God praises and consoles His most distinguished servant the Prophet Muhammad, upon him be peace and blessings, not with His extraordinary favors but with his laudable virtues and praiseworthy qualities, declaring: You stand on an exalted standard of character (68:4). His nature was the aim and fruit of his creation. Since the Prophet’s conduct embodied Islam and the Quran, when his wife Aisha, may God be pleased with her, was asked about his conduct by Sa’id ibn Hisham, she answered: “Do you not read the Quran? His conduct is (the embodiment of) the Quran.”

The verse: You stand on an exalted standard of character (68:4) shows that the incomparable conduct of the Prophet was based on the Quran. In addition to his outer and inner faculties and senses, and the material and immaterial aspects of his creation and character, the Prophet was endowed with all potentialities needed to be the most forward and greatest representative of human virtue. Developing these potentials to the highest degree possible, he attained the highest degree of human perfection.

Not content with this state, as is declared in the verse: Surely, in the Messenger of God you have a good example for him who hopes for God and the Last Day, and remembers God much (33:21), he established the most excellent example for his followers and thereby gradually transformed them into the most virtuous community of all time. With such sayings as: “The most perfect in belief among the believers are the most perfect in conduct” ; “A man can cross with good conduct the distances which he cannot with acts of worship and adoration” ; and: “The first virtue to be weighed in the Balance (in the other world) is good conduct,” and by employing the perfect, fruitful principles he brought to perfect humanity, he guided his followers to the realms where angels move.

The signs of good nature have been summarized as follows: a person possessing this quality does not hurt anybody by either word or deed, overlooks those who hurt him or her and forgets the evils done, and returns evil with good. The Prophet, upon him be peace and blessings, who is praised with the verse: You stand on an exalted standard of character (68:4), is the most excellent example of these virtues. He was not offended by the one who stood before him and told him to be just, by the one who pulled his robe from the back and hurt him, by the one who threw dust on his head and insulted him, or by the one who slandered his innocent and beloved wife Aisha. In fact, he visited each of these individuals when they became ill and followed their funeral processions. He did so because good nature was a dimension of his blessed existence.

Many people seem to be good natured, mild-mannered, and humanitarian, although good conduct and mildness are no more than affectations. When they experience a little irritation, anger, or harsh treatment, their true nature will be revealed. One who has good nature does not change his or her manners even when in a hellish state, but remains mild and shows no harshness. A heart open to good nature is like a very broad space in which one can bury one’s anger and rage. As for those intolerant and impatient ones who display bad conduct, they are, like Cain, more stupid than the raven, and can find no place to bury their anger, hatred, and ill feelings.

Let us conclude this discussion with the following couplet:

It is by good nature that a man can be perfected;

It is by good nature that the order of the world is maintained.

Notes

1. Sulayman ibn Ash’as al-Sijistani Abu Dawud, Sunan Abi Dawud, 4 vols. (Beirut, n.d.), 14; Ibn Hanbal, Musnad, 2:250.
2. Muslim, “Musafirin,” 139.
3. Abu Dawud, Sunan, 14; Ibn Hanbal, Musnad, 2:250.
4. Al-Haythami, Majma’ al-Zawa’id, 8:24.
5. ‘Ala al-Din ‘Ali al-Muttaqi al-Hindi, Kanz al-’Ummal fi Sunan al-Aqwal wa al-Af ‘al, 8 vols. (Beirut: 1985), hadith no. 5160.
6. Al-Bukhari, “Adab,” 95; Muslim, “Zakat,” 142.
7. Al-Bukhari, “Khumus,” 19; Muslim, “Zakat,” 142.
8. Al-Bukhari, “Shahada,” 15; Muslim, “Tawba,” 56.
9. Abu Dawud, “Jana’iz,” 1.

Many people think of supernatural phenomena as miracles or as divine signs. However, through his studies in biology, the immune system and DNA, Dr. Denis Alexander concludes that what is called natural is nothing less than miraculous. Dr. Alexander, a renowned molecular biologist, is constantly amazed by the extraordinariness of the human immune system. He explores the relationship between science and religion as the director of the Faraday Institute at Cambridge University. Dr. Alexander writes, lectures and broadcasts widely in the field of science and religion. Since 1992 he has been Editor of the journal Science and Christian Belief, and currently serves on the National Committee of Christians in Science and as a member of the International Society for Science and Religion.

M&B: Let’s talk a little bit about your research on the immune system and cancer. Specifically regarding regulatory T-Cells.

Actually, I’m working on the very early stages of T-cell development in the thymus. T-cells, which are the white blood cells that defend us against viruses and bacteria, all have to be “educated” in the thymus. They have this very strict program of education, and then only a very small percentage graduate, so only about 1 or 2 percent of all the T-cells will actually graduate. If you had that sort of system in our own educational system, I think we would look on it as not very successful. If 98 percent of all our undergraduates die, we wouldn’t think that was a very good system. But in the thymus it actually works very well. So what happens is your T-cells learn to only recognize foreign antigens like viruses and bacteria – things that are going to invade your body – and they won’t attack your own tissues. That’s the kind of education that the thymus gives. It’s really a wonderful, amazing system.

M&B: What is the specific role of the T-cells and how is it related to the functioning of other elements within the immune system?

Well, basically the whole immune system is highly complex, so T-cells are not the only cells around. You have B-cells, you have natural killer cells, you have whole sets of different types of cells, and they’re all doing different jobs. They all have to cooperate together.

Then you have killer cells, or K-cells. These natural killer cells are those which are involved in the immediate reaction of the immune system to antigens once they attack your body. So the body is set up so you have an immediate response system, whereby-it’s like mobilization of an army-you can mobilize small bits of your army in the first 24 hours. That’s the natural killer cells. They will give you immediate defense. You have helper T-cells that help the B-cells in order to develop and to make antibodies. B-cells give you your acquired immune system, which is the immune system that only comes into action after about 10 to 14 days. So, that’s the mobilization of the full resources of your army. Thinking of it in terms of a kind of defense system is actually quite useful. T-cells are involved in wiping out virally infected cells, and so they all coordinate together in a rather delicately controlled, complex balance, but they all have to coordinate with each other to make sure the system works properly. It’s amazing how it works; actually, I think, it’s remarkable.

M&B: The natural killer cells attack the cells which are not supposed to be there. But how can they recognize cells that are part of us, how do they define the “self.” Would you give us a parable about how the natural killer cells work?

In the natural killer cell system, there is also the idea of the missing self, which is the idea that when there’s a certain molecule which is not there, natural killer cells won’t attack. Therefore, they don’t recognize our own tissues. This is the idea of the missing self hypothesis. They will only attack things which they perceive to be foreign. It’s like the foreign thing is coming in and waving a flag which says, you know, I want to be attacked, I should be attacked. And that’s set up by a very carefully balanced system, between activating receptors and inhibiting receptors which operate together in order to bring that to pass. It’s quite a complex molecular system, in fact.

M&B: But it still doesn’t provide 100% support. Obviously we are not totally immune to disease.

Now, once the T-cells get out in the periphery, that’s to say the blood stream and the spleen and the other places, in the gut and so forth, then there are other mechanisms in place to keep them under control and to make sure that they don’t actually start attacking your own body. And of course, now and again, very sadly, that does happen. There are mistakes made, and so you get things like diabetes and rheumatoid arthritis and these sorts of auto-immune diseases, and that’s where the T-cells start attacking the tissues of your own body. It’s amazing, most of the time that doesn’t happen, and that’s all up to the thymus, since it educates the T-cells.

M&B: In what way do these cause cancer?

We’re actually working on a mouse model of the human cancer called Lymphoma. It happens when T-cells don’t stop dividing, and so if you look at all the immune cell types of cancers, they’re all very similar kinds of things. Certain cells of the immune system actually undergo errors in the early part of their development, and instead of moving on to the next stage of development they get stuck. Then, they carry on dividing and proliferating, filling up the whole of your bone marrow or your blood stream, and so you end up with white blood cell leukemia.

I could just tell you one example, the one that we’re working on. Basically, what happens is that when normal T-cells get DNA damage, they die. So as a program, when you get any kind of DNA damage, there’s a trigger that happens, and those cells will be wiped out by a process called apoptosis, which is programmed cell death. All of our cells, actually, have the ability to do that. But now and again something happens, an acrogenic change takes place, which is a change in a gene which causes cancer, and that prevents the cells from dying by apoptosis. And so, the cells that have this DNA damage are left to proliferate, and once you get DNA damage, then the chromosomes become unstable, and you get more DNA damage. It’s like a kind of downward spiral. Then all kinds of things happen that cause that cell to become a cancer cells, which will carry on dividing and dividing and eventually kill the mouse, or kill the patient. We’ve just recently identified one of the mechanisms whereby those cells that should die are kept alive, and it’s a very, very subtle mechanism, which is one particular protein, one particular stage of development to t-cells in the thymus.

M&B: We think that dying is a bad thing. But to give an example at the cellular molecular level, “not dying” is actually a bad thing.

Yes, I mean, death is built into our genomes, essentially. You know, we will die eventually because of all kinds of mechanisms, including the shortening of our chromosomes. The cells will only go through a certain number of divisions before they come to the end of their life. There’s a sort of internally clock. Now, of course, it’s possible that we can patch up all these things, we can use stem cells, we can use transplants. If someone needs a new heart or a liver, we give them a new heart or a liver. So clearly we can extend life by years, by decades, and that process is obviously already happening. In fact, I would say that the priority in that way is not to give wealthy people just a few more decades of life, but to try and help those people in lower income countries where what they need is better food and better water, a good water supply, basic medical care, and therefore their average life will then go from 35 up to 65 or 70 years old and so on. So, I slightly worry about this huge activity in the wealthy world to try and make ourselves immortal, and try to extend our life by another decade or so, when such big slices of the world’s population are still lacking even the very basic medical care that I think they should be given. We can extend life by potentially quite a lot, but to become immortal, I don’t think so. I think mortality is written into our genes.

M&B: As a scientist you study the immune system, as well as life and death. But as a person, what do you feel about them? Would you comment on the purpose behind of all these processes?

Well, I suppose that as someone who believes in God, I would see all of these processes that we describe as biologists, as scientists, as part of God’s processes, that part of His intentions is to bring about His own particular ends and purposes on this earth. And clearly, I think one of those purposes is transience. You know, if you have life and death, you have things in process, you also have transience. We’re not immortal-not in our present bodies at least-we don’t display the qualities of immortality. So therefore, I think that fits with the idea of a God who wants to bring in processes which involve life, and they also involve death, and they involve moving on. So we have dynamic systems. We’re not static, we’re not little puppets, you know, who always have the same kind of characteristics. We are in motion, we’re always changing, we’re always moving on. That’s what we see in human society as well as in the whole world of biological diversity. It’s a dynamic process of things, changing processes, which come into being and which go out again, and life and death go together. You know, you can’t have life without death.

M&B: But there is a sense of awe when you think about the tiniest T-cells getting educated. For some people, it would seem amazing and even miraculous as splitting the water with a simple rod, if you don’t mind me saying this.

It is amazing, and I’m constantly amazed and when I look at the immune system, and when I look at the way cells work, when I look at the way, indeed, biochemical signaling pathways operate together. I think that fact is quite remarkable, actually, and should arouse our awe and our wonder, and indeed many people look to God as a natural overall explanation. Not in the sense of replacing God in the gaps of our knowledge, but as our knowledge increases, then our understanding of God’s power and wisdom in creation increases along with that, and to me is real natural theology. Natural theology is not looking for the gaps in our knowledge, but as our knowledge increases coming to a greater appreciation of what God can do. It’s interesting. Actually, just a couple of days ago, I was listening to the account of a Chinese student in Cambridge in the UK, where I come from, and she was telling us about how she had come to have faith in God. What she said was that she was in her biochemistry lectures in the university, and the lecture was about how DNA in each cell, if you stretch it all out, it actually comes to two meters long. You know, if you take the DNA from any one cell, the packing of the DNA is so amazing that when you pull it out, it is two yards long. And she was so amazed by that, she suddenly thought, in the middle of the lecture, there’s got to be a God. There must be a God. It’s so wonderful, you know, she was amazed by this wonderful thing, and she’s moved to belief in God, and I thought that was really quite interesting.

M&B: Do you think arriving to this conclusion has to do with having an open mind, in many ways?

Yes, I think it does. I think the problem is that people brought up in a scientific culture can so often think that the scientific story is the only one that matters. They’re like people reading a book, but they see it and they only look at the black ink on the page, but when they look at the structure of the words they miss the whole message. And I think that’s always a danger in the reductionist approach. Now I’m a reductionist in the methods I use in analyzing the immune system or looking at cancer mechanisms, and that sort of reductionism is very important for us as a methodology we use in our science. But, of course, we shouldn’t then move from that into thinking that reductionism gives us the final story. It just gives us one slice of the story, one little layer of the overall story. I think we then have to take a step backwards and start looking at the message as a whole. That’s terribly important, and it’s always a temptation for people who are deeply imbedded in the scientific community or living in a scientific culture of some kind just to think the scientific story is the only one that matters, but clearly that’s not the case.

M&B: You talked about a sense of awe that surpasses the mind. But when we attribute unexplained things to God, some people tend to think that God is the God of mystery. God is the God of miracles, God of the unknown and the God of the gaps. Would you please comment on this idea?

I think the idea of the God of the gaps is a very unfortunate idea; that has a very long history. Actually, it goes back many centuries. I’m not quite sure when the idea first began. But I think it’s always been tempting as science got going, especially in the nineteenth century when science was less developed than it was now.. It was a temptation for people to try and locate their God within the present gaps of the scientific knowledge. So obviously, as the gaps are closed, so one’s understanding of God will shrink. God is then located in smaller and smaller mysteries.

Now, I think that’s very unfortunate from a theological point of view, because certainly as a Christian I believe in a God who is the author of creation, and who is the author of everything that exists. Therefore, the author writes everything, the author writes the whole book. And it would be very odd if you were looking in the book, if you went to chapter 9 and you went to the second paragraph and you said, “Ah-ha! Now I’ve located the mystery of the author in the second paragraph in chapter 9.” That would be a silly kind of argument. And I think that’s the same kind of argument that the God of the gaps people use. They try and locate bits of the book, forgetting that either the book has an author, or it doesn’t. There’s either someone who is writing the text or there isn’t. So, I think God is in charge of all the processes of the world, upholding and sustaining the whole of the book of creation, if you’d like to use that analogy. So whether we have current gaps in our knowledge now has no theological significance as far as I’m concerned. It doesn’t matter. It’s of no particular interest, so theology has no hidden investments in gaps in our knowledge. It really doesn’t matter. It simply says we’re ignorant about many things. Which is good, because otherwise I would be out of a job.

Interview conducted by Mustafa Tabanli for Ebru TV for the Emmy Award winning television series Matter and Beyond.

Starting with the following classification of the sciences laid out in Shams al-Din Muhammed al-Amuli’s Nafa’is al-Funun (Precious Elements of the Sciences), a treatise written during the fifteenth century, may be helpful to reveal this point1:

The theoretical aspects of what we call positive sciences today (physics, chemistry, biology, medicine, geology, astronomy, cosmology, etc.) were all called natural philosophy not only by Islamic scholars but also by the scientists, philosophers, and theologians of other traditions up to the Age of Enlightenment, and that type of science was considered a lower science in the hierarchy of existence. The intermediate science was mathematics, which included music, while metaphysics occupied the place of the highest science. Not only philosophy, ethics, economics, and politics but also intellectual and transmitted religious studies are covered by the Islamic conceptualization of sciences. The classification of sciences was always considered to be important in Islamic tradition and many Muslim scholars have provided different classifications.2 The essential point here is that all the Islamic classifications of sciences, as in this specific one, were based on the Islamic doctrine that there is a hierarchy of existence (and therefore knowledge) from Unity to multiplicity, from the Divine Names and Qualities to each creature on a particular level of existence, and from the Meta-cosmic Reality to the cosmos consisting of the seven heavens and the earth which is nothing but the manifestation of the Meta-cosmic Reality. Therefore, all sciences, in the Islamic conceptualization, were means of gaining this kind of knowledge.

In contrast, the modern conceptualization of the sciences is subservient to the idea that reality can only be examined by its highly specific and restricted experimental method. Thus, the modern conceptualization implies, due to this method, that theories, doctrines, and principles concerning non-observable realities cannot be scientific. A natural consequence of this way of thinking is to be skeptical about metaphysical realities in the belief that the absolute reality is the physical one. From this point of view, therefore, neither religion nor metaphysics are accepted as scientific disciplines. Although there are some departments such as politics, economics, and ethics under the umbrella of humanities and arts, the traditional occult sciences such as astrology, alchemy, magic, and the interpretation of dreams cannot find a place in modern universities, in spite of the fact that their derivatives are still alive in both traditional and modern societies. At this point it may be illustrative to remind the reader of the following verses of the Qur’an: “Thus, did We establish Joseph in the land (Egypt), that We would impart to him knowledge and understanding of the inner meaning of events, including dreams” (Yusuf 12:21), “Solomon never disbelieved. Rather, the satans disbelieved, teaching people sorcery and the (distorted form of the) knowledge that was sent down on Harut and Marut, the two angels in Babylon. And they (these two angels charged with teaching people some occult sciences such as breaking a spell and protection against sorcery) never taught them to anyone without first warning, ‘We are a trial, so do not disbelieve’” (Al-Baqarah 2:102), which can be interpreted as evidence of the existence of such sciences, although the Qur’an itself condemns those

And (yet) they learned from them (the two angels) that by which they might divide a man and his wife. But (though they wrongly attributed creative power to sorcery, in fact) they could not harm anyone thereby save by the leave of God. And they learned what would harm them, not what would profit them. Assuredly, they knew well that he who bought it (in exchange for God’s Book) will have no share in the Hereafter. How evil was that for which they sold their selves; and if only they had known. (2:102)

In the Islamic conceptualization of sciences, the natural sciences possessed a place in the hierarchy of knowledge so that there were no contradictions between them and religion. The whole worldview was religious and this perspective provided sufficient space for the cultivation of positive sciences yet in the guidance of metaphysical principles from a higher level of knowledge. The history of Islamic sciences is full of striking examples of success, from the modern scientific perspective, in cosmology, geology, mineralogy, botany, zoology, mathematics, astronomy, physics, medicine, pharmacology, agriculture, and irrigation, any of which could be the topic of a future article. This is why, as people learn even more natural sciences, they believe more in those times. That is why most of the greatest Muslim scientists were distinguished philosophers and theologians at the same time. They are those who the Qur’an identifies in the phrase, “Of all His servants, only those possessed of true knowledge stand in awe of God” (Fatir 35:28).

It is because of the modern conceptualization of sciences that religion and science are separated from each other and have become strangers on the assumption that they have their own realms to speak about.3 The roots of this way of thinking goes back to Descartes (1596–1650): “Descartes, who appeared with the thesis that ‘metaphysics cannot be a science,’ said that knowledge can only be obtained by the investigation of measurable and divisible things and he limited the question of science to only matter; since that time the followers of Cartesian philosophy have always talked in a similar way.”4 Yet, both religion and science try to find answers to the questions of who we are, what the meaning of life is, where we come from, and where we are going to. We cannot imagine any technological advancement which satisfies these eternal concerns of humanity which reflect its relation to eternity.

By definition, the modern sciences have bound themselves to the existence of a finite and relative reality. Their methodology is very effective and there is nothing wrong with it unless it is utilized for abusing natural sources or any other form of corruption. Those sciences may even provide some clues about the higher level of existence as in the case of quantum mechanics which has destroyed the deterministic worldview of classical (Newtonian) physics. However, to our mind, there is a problem with the modern conceptualization of sciences which does not accept any notion of the hierarchy of existence nor any means of studying and investigating those levels of reality.

Dr. Ali Sebetci is an Assistant Professor of Computational Chemical Physics, Zirve University Gaziantep, Turkey.

Notes

1. Nasr, Seyyed Hossein. Islamic Science, An Illustrated Study, World of Islam Festival Publishing Company Ltd, 1976.
2. Bakar, Osman. Classification of Knowledge in Islam, Islamic Texts Society, 1999.
3. Edis, Taner. An Illusion of Harmony: Science and Religion in Islam, Prometheus Books, 2007.
4. www.herkul.org, Kırık Testi, September 12, 2005.