Every essential oil gets its uniqueness not just due to one of its components but because of its delicate and complex admixture. The individual perfume and therapeutic value of each essential oil depends on this balance.

What is aromatherapy?

Aromatherapy is the practice of using essential oils, also known as volatile plant oils, for physical and psychological health. These essential oils and/or essences are concentrated liquids that are extracted from many different types of wild or cultivated plants. Essential oils can be obtained from different parts of the plant, such as the flower, leaves, fruits, bark, roots, and resins. Some examples of essentials oils are Agar oil, highly coveted for its wonderful fragrance, and Geranium oil, used in herbal medicine. As for essences, they can be obtained not only from flowers and resins but also from chemicals such as benzoins, and plants such as gaiacs and pines. Some examples of resins that can be used for their essences are Asafoetida, which is dried latex that certain Ferula plants exude from their tap root, and Myrrh, which comes from thorny plants of the genus Commiphora.

A brief history of aromatherapy

It’s hard to say when people first started using aromatherapy, partly because the practice of using plant-derived ingredients for medicinal (and other) purposes is as old as time. There is evidence that the Chinese may have used aromatherapy several thousands of years ago, with an emphasis on maintaining harmony and equilibrium. Some years after this the Egyptians were able to develop a machine that could distill cedar wood oil. Later on, the Greeks adapted aromatherapy from the Egyptians. “Istenshaque,” a form of aromatherapy, was first practiced in the Greek system of medicine by Hippocrates (460-370 BC). In the 11^th century, the renowned Avicenna developed a coiled cooling pipe that made the essential oil distillation process much faster. The term “aromatherapy” was eventually coined by the French chemist and scholar Dr. Rene Maurice Gattefoss’e (1881-1950) in 1930 and thereafter practiced as a medical science for the treatment of various diseases.

What are essential oils composed of?

From a chemical analysis standpoint and by chromatography it is evident that essential oils are not single entities but can instead be classified as compounds. Additionally, essential oils are volatile in steam, which means they will turn into a gas in the presence of steam. They differ entirely in both chemical and physical properties from fixed oils, which are also known as non-volatile oils. Animal or vegetable oils are very common types of fixed oils. Essential oils consist of many organic constituents which unite in a delicate and complex balance to produce a wide range of therapeutic and olfactory qualities. For example, the oil of the eucalyptus leaf contains no less than 250 different constituents. In one study, researchers were able to identify 40 different compounds in tea tree oil using chromatography methods (Journal of Agriculture and Food Chemistry). Every essential oil gets its uniqueness not just due to one of its components but because of its delicate and complex admixture. The individual perfume and therapeutic value of each essential oil depends on this balance.

Scope & methods

• Olfaction (shamoom): Aromatic medicines either in dried or liquid forms are kept in a vessel and the fumes are inhaled. Rose oil is often used in this manner.
• Inhalation (lakhlakha): Aromatic medicines or pungent medicines either dried or liquid forms are kept in a wide mouthed bottle and then inhaled. With this method the vapors of the medicines not only reach up to the nose but can reach down in to the respiratory passage as well. Camphor is a common choice for inhalation therapy.
• Massage (dalak): Some treatments involve massaging the oil into the skin directly, and can be one of the more effective treatment methods.
• Poultices: Essential oils used in poultices bring out impurities of the skin. These treatments sooth irritation and relieve congestion and pain. Most frequently, poultices are made up of linseed (Alsi) or mustard. These are particularly useful for chest complaints and skin diseases.
• Compresses: Used externally, particularly on eyes. They can be either hot or cold depending on the effect required.

Base oils and carrier oils

Most essential oils are not used in their pure, undiluted sate. Rather, they are mixed into a fixed plant oil base, like almond, soya, or wheat germ. These base or carrier oils act as balancing and stabilizing agents. They are typically pure, have little to no smell, and are easy for essential oils to dissolve in. The ratio of essential oils to base oils differs for each oil. For example, 2 to 3 drops of essential oil to 5 ml of base oil can be used for the body, and 1 drop essential oil to 5 ml base oil can be used for the face.

Some commonly used oils

• Almond oil: Oil extracted from bitter and sweet almond.
  Constituents: Olein is the chief constituent. Other constituents are glyceride and linoleic acid.
  Action: Skin softening agent, lubricant, nourishing and revitalizing.
  Uses: Wonderful for dry, wrinkled hands. Very beneficial for eczema and skin irritation of any kind.
• Castor oil:
  Constituents: Major constituents are palmatic, fatty acids, ricinoleic acid and glycerine.
  Uses: as soothing agent for skin rashes, in embalming, eczema, dryness of the skin.
• Soya oil:
  Constituents: Oleic, linoleic, stearic and palmitic acid.
  Action: Lowers cholesterol levels.
  Uses: To be taken every day in salad dressing or with rice dishes.
• Sage leaf (Salvia officinalis)
  Action: Antiseptic, astringent.
  Uses: Mouth washes and gargle, Alzheimer’s disease, memory loss.
• Thyme & thyme oil (Thymus vulgaris)
  Action: Antiseptic, anti-tussive, expectorant, spasmolytic.
  Uses: Cough cold, spasmodic pain.
• Lavender oil (Lavendula angustifolia)
  Action: Masks disagreeable odors, heals skin burn and acts as relaxant in premenstrual tension.
  Uses: In ointment, rheumatic pain.
• Aniseed (Pimpinella anisum)
  Action: Carminative, appetizer, hepto-tonic, stomachic, diuretic, emmenogogue, galactogogue, analgesic.
  Uses: flatulence, loss of appetite, liver disorders, indigestion, renal disorders, to stimulate lactation, for pain.
• Fennel (Foeniculum vulgare)
  Action: Carminative, stomachic, diuretic, emmenogogue & galactogogue and vermicide.
  Uses: flatulence, loss of appetite, indigestion, renal disorders, to stimulate lactation and worm infestation.
• Cumin (Cumin cyminum)
  Action: General tonic, digestive, antiseptic, bactericide, carminative, detergent (Jaali)
  Uses:Indigestion, loss of appetite, infections, flatulence, skin disorders.
• Cinnamon oil (Cinnamomum zeylanicum)
  Action: Rubefacient, carminative, powerful germicide, anti-rheumatic, digestive, analgesic, detergent.
  Uses: Skin disorders, flatulence, infection, arthritis and indigestion.
• Camphor (Cinnamomum camphora)
  Action: externally: rubefacient, internally-mild antiseptic, carminative, antipyretic.
  Uses: skin disorders, infections, flatulence and fever.
• Caraway (Carum carvi)
  Action: Carminative, antispasmodic, galactogogauge and emmenogogue.
  Uses: Flatulance, colic, stimulate lactation and dysmenorrhea.
• Myrrh (Commiphora)
  Action: Antiseptic, antibiotic, stomachic, emmenogogue, diuretic, anti-inflammatory, wound healing properties.
  Uses: as an essence and in perfumes, mouth wash, in anti-ulcer treatment and is cytoprotective.
• Clove oil (Eugenia caryophyllus)
  Action: Stimulant, antiseptic, stomachic, expectorant, sedative, carminative, antispasmodic, digestive.
  Uses: Mouth and tooth infection, flatulence, rheumatic pain, bronchitis, cold.
• Eucalyptus oil (Eucalyptus globus)
  Action: Decongestant.
  Uses: Internally: Mixtures, inhalations, lozenges. Externally: In ointments and liniments.
• Chamomile (Matricaria chamomilla)
  Action: Antiseptic, anxiolytic, digestive, disinfectant, carminative antipyretic.
  Uses: Insomnia, headache, migraine, facial neuralgia, sinusitis, dermatitis, acne, eczema, abscesses, boils, amenorrhea, pre-menstrual tension, cystitis, colic, loss of appetite.
• Sandal wood (Santalum album)
  Action: Calming action on dry skin, aphrodisiac.
  Uses: For dry and chapped skin.
• Rose oil (Rosa domascena)
  Action: Cardio tonic, resolvent, anti-inflammatory.
  Uses: In perfumery, palpitation, inflammation.

Precautions while using essential oils

Although essential oils are useful for treating a number of ailments you should still take the necessary precautions before using them. For example, you should always perform a skin test before using an essential oil, since everyone is unique and reacts differently to different oils. Body size, age, and sex also makes a difference. As for storage, essential oils should always be stored in dark glass bottles away from sunlight.

In our era that is characterized by stressful environments and ever-changing life styles, essential oil aromatherapy offers an optimal answer to the emerging health burden of degenerative diseases. It not only offers therapeutic but also preventative and restorative health benefits, without most of the side effects of modern treatment schedules. Hence aromatherapy with its wide scope and application potential offers a therapeutic solution for not only diseased body systems but also soothes the soul and the spirit, thereby taking care of the stress component that is prominent in many illnesses.

Distribution and density of the hairs in our body is coded in our genes. This program is activated after birth and hair roots are formed at around 8th-10th week of pregnancy. The hairs that cover the fetus are thin, short, and weak. The growth of hairs is completed in the 22nd week. Number of hairs in a fetus does not change much according to gender. Later on in a person’s life, hairs can become dense or rare, owing to factors such as race, age, gender and hormonal state. There are hair roots covering almost all over our body except for the soles, palms, forehead, the areas under the eyes, on and behind the ears.

A hair is made up of the hair root and the hair shaft on it. A hair root is surrounded with two layers. The duty of these layers is to prevent harm to the hair shaft and let the hair grow in the right direction. A hair root is a multilayered structure where every layer has a different function. The papilla is in the base of the hair root and it basically serves to send nourishment to hair cells. The upper layer of the hair shaft is the hard substance called keratin. The innermost layer, which can be seen as the spinal cord of a hair, does not exist in every hair shaft. The second layer, known as the cortex, constitutes most of the hair shaft. The color of hair is mostly determined by the pigment in this layer. The outermost layer is the upper skin of the hair.

Hairs in different parts of the body have their peculiar forms of and limits to growing. Under the control of hormones, hair roots cause hairs of different properties—such as thickness and color—to form. The hairs in moustache, armpits, between the legs, beard, and on the head grow fast and continually. On the other hand, the hairs on our arms, chest, back, legs and including those in the eyebrows grow very slowly and they know their limits. If the person does not own functional testicles, there may be no hair in certain areas of the body except for the hair on his head.

Most of us are apt to think that certain stories make our hair curl; actually, hair erector muscles are the unsung heroes of those stories. Under every hair in the body, there is an erector muscle that makes it move. These muscles have important functions for the body.

Firstly, it helps the oil glands carry out their function. The oil sacks are located on the surface of a hair. The sizes of these sacks are around 0.2-2 millimeters. Sacks are in the form of clusters. Oil glands are also placed all over the body, accept for the soles and palms. They are the natural “lubricants” for the skin and hairs; they protect the skin from the damage of drying up. Every gland under the skin has a channel. There are alveoli that open to every channel. When the hair muscle is stimulated, the hairs become erect and the connected gland start secreting a substance called sebum. The glands empty their contents to the body of the hair.

Regulating the acidity (pH) level of the skin is among the duties of the hair erector muscle and it produces a protective gel. The oily secretion forms a thin layer of gel; as it serves protecting the skin from heat and cold, it is given an antibacterial effect as well. The natural coating of the skin prevents reproduction of harmful germs. The pH level of the skin is 5-6 and it does not allow bacteria to grow. If this substance is not secreted from the skin, the pH acidity shifts toward alkali, moisture level of the skin increases; the fat layer and then the natural coating is damaged. Thus, germs find a suitable environment to reproduce.

Hair erector muscles are also given a role in adjusting body heat. The hairs in the human body are not related to heat isolation. When the body is exposed to cold environments, the mechanisms that increase body heat are activated. When sympathetic nervous system stimulates hair erector muscles, they contract, hairs bristle, and the body heat is tampered through the reduced heat release. Sometimes, even the invisibly small hairs erect and goose bumps appear on the skin. The purpose is to form a screen for heat. They also allow for perspiration in hot weather and help the body to cool down. In addition, hair erector muscles serve as touching receptors as well. The receptors in hairs easily detect objects on the body surface. Hairs that are activated by touch stimulate the nerve tissue in their base. In a way, they keep a round the clock watch for the body; as tiny and unsung heroes.

They say that perfection is hidden in details, which is also very true for hairs. And perhaps, the secret to appreciation lies in recognizing details, and appreciating their perfection.

Less well known is that research is also continuing into the scent of repellents to deter pests like insects and ticks. Various plants are known for the effects of their aroma, and are in widespread use for protection, especially in very hot and humid climates where there are a great number of arthropods; for instance, it is known that mosquitoes will not approach a house that has basil plants on the windowsill.

Another plant which is well known and used commonly for its scent is “patchouli” (pogostemon cablin), the scented essential oil of which is obtained by steaming the plant and collecting the oil which emerges. The plant is a member of the mint family, and its actual origin is India, where its scent can be found even in the famous Indian ink. Patchouli leaves used to be placed between carpets and rugs made in Iran and Turkey to protect them from any harmful pests or insects before they were sent to Europe. During the Victorian period carpets, shawls and rugs exported from India were also sprinkled with the fragrance of patchouli to protect them from moth, In fact any carpets, rugs or shawls that did not have the scent of patchouli were not favored because they were believed to have been manufactured in Europe. The fragrance of the plant, which is longer lasting than most other scents, is believed by the Chinese, Japanese and Arabs to prevent the spread of infectious diseases and also used frequently in perfumes and soaps. Widely used in Europe in the eighteen hundreds, patchouli became the most popular fragrance of the generation in America in the sixties.

The research into patchouli has been limited so far and scientific observations are insufficient; nevertheless, the chemical composition of the various scents found in the oil of this plant have been identified, and the long human experiences of using this plant and its fragrance may hold great significance for scientific research in the future.

The plant contains patchouli alcohol, pogostone, friedelin, epifriedelinol, pachypodol, retusin, oleanolic asid, beta-sitosterol and daucosterol, most of which prevent nausea. It has also been found to contain alpha-bulnesene, which prevents the clotting of blood. In addition, according to an article in the 2008 February edition of the Phytotherapy research journal, since the oil obtained from patchouli essence is an effective fly killer, the oil could also be an effective as a component of insect repellents and might even be an effective arthropod and tick repellent.

Looking at these studies we clearly see other ways in which we could benefit from this substance; for instance, by adding a few drops to water we could use it in household cleaning and therefore get rid of unwanted odors at the same time as preventing insects in the home without the use of carcinogenic chemicals. The oil is also known to be used to prevent fungus, to reduce perspiration and eliminate unwanted body odors and for dietary purposes, due to its effectiveness in reducing the appetite.

Moreover, patchouli has also long been a fragrance very much sought and used as a form of treatment for its soothing qualities and positive effect on spiritual health. Martin Henglein, who was one of the founders of aromatherapy and developer of the theory of the curative aspect of the fragrances of plants, recognizes geranium, rosemary, bergamot, and patchouli as the four primary aromas, and he emphasizes that these four fragrances perform various functions. Geranium can prevent addictions from progressing and even assist people in abandoning addictions and bad habits. For instance, the role geranium plays in giving up smoking is indisputable: when the desire to smoke increases and becomes unbearable the aroma of geranium temporarily eliminates the desire to smoke. According to Henglein, rosemary improves memory while bergamot increases activity in the brain and the ability to understand; patchouli activates the mechanism which motivates a person’s energy.

Robert Tisserand, owner of a treatment center in England, believes that certain fragrances can also cure psychological illnesses, Tisserand says that these aromas have a positive effect on the signal molecules (neurotransmitters) that provide communication with the nerve cells and can help to cure psychological problems. Fragrances encourage the body to release endorphin, a substance which resembles morphine (a pain reliever) and this is why rose oil, jasmine, sage, cananga (ylang ylang), patchouli, and grapefruit are recommended for depression, to increase confidence, and to help with abnormalities of sexual function. If patchouli is used in excess, it allegedly may cause a sedative effect or may reduce sleep. Otherwise, it is claimed to have a balancing effect on the body’s energy and psychological condition, inspire a sense of calmness, eliminate laziness, support treatment of addictions, and relieve feelings of fear and depression.

Everyone knows that charming fragrances enhance positive thought and feelings, and we also know the negative aspects of bad odors. It is reported that the Prophet Muhammad, peace be upon him, said, “I have been made to love perfume,” drawing attention to the importance of pleasant fragrances and reminding us that Jacob received the glad tidings that his son Joseph was still alive because of the scent of his shirt.

References

• Guan L, Quan LH, Xu LZ, Cong PZ. (1994): Chemical constituents of Pogostemon cablin (Blanco) Benth. Zhongguo Zhong Yao Za Zhi. 1994 Jun;19(6):355–6, 383.
• Yang Y, Kinoshita K, Koyama K, Takahashi K, Tai T, Nunoura Y, Watanabe K.(1999): Anti-emetic principles of Pogostemon cablin (Blanco) Benth. Phytomedicine. 1999 May, 6 (2): 89–93.
• Luo J, Guo X, Feng Y. (2002): Constituents analysis on volatile oil of Pogostemon cablin from different collection time cultivated in Hainan. Zhong Yao Cai. 2002 Jan. 25 (1): 21–3
• Hsu HC, Yang WC, Tsai WJ, Chen CC, Huang HY, Tsai YC. (2006): Alpha-bulnesene, a novel PAF receptor antagonist isolated from Pogostemon cablin. Biochem Biophem Biophys Res Commun. 2006 Jul 7;345(3):1033–8.
• Tsai YC, Hsu HC, Yang WC, Tsai WJ, Chen CC, Watanabe T. (2007): Alpha-bulnesene, a PAF inhibitor isolated from the essential oil of Pogostemon cablin. Fitoterapia. 2007 Jan. 78 (1):7–11.
• Pavela R. (2008): Insecticidal properties of several essential oils on the house fly (Musca domestica L.). Phytother Res. 2008 Feb;22(2):274–8.
• Jantan, I. and Zaridah M. Z.(1999): Development of Environment-Friendly Insect Repellents From The Leaf Oils of Selected Malaysian Plants. ASEAN Review of Biodiversity and Environmental Conservation (ARBEC) November–December 1999, p.1–7.

Most, if not all, of water’s anomalous properties make life possible. To name a few of its many oddities, water is the only material that naturally exists in all possible forms (solid, liquid, and gas) on earth. Of all known chemical compounds, water has the second highest capacity to store heat, which is crucial for climate regulation and keeping living organisms’ body temperatures constant. Water is the second best heat-conducting liquid (after mercury), and this helps large masses of water to reach uniform temperatures quickly. Water has an astonishingly high heat of vaporization which eases body temperature regulation for humans and animals via providing a cooling system through sweating. This high heat of vaporization also prevents dehydration.

The absorption coefficient of water is a million times lower for the visible region of light than the rest of spectrum, a property which enables passage of the useful and prevention of the harmful rays from the sun, and makes the earth amenable to the accommodation of biological life. Furthermore, the greenhouse effect which keeps the Earth’s climate at moderation also stems from this aspect of water. Because the sunlight that is reflected from the Earth is mostly in the infrared region, it is effectively absorbed by the water vapor in the atmosphere due to water’s higher absorption of light within the non-visible regimes, and hence the heat does not escape from the earth.

Water is one if the best solvents, which is very important for cleansing. Finally (and thankfully), water does not display its peculiarity when it comes to taste. Such a “famously odd” molecule is somewhat ironically tasteless and odorless, and extremely easy to drink and consume.

“If We so willed, We would make it bitter and salty. Then should you not give thanks?” Waqi‘ah (56:70)

Although each of the aforementioned physical aspects of water deserves mentioning in its own right, from here on we will focus on water’s properties from a biological standpoint. To this end, we will first introduce some aspects of water, look at the interaction of water with bio-molecules, and finally elaborate on three particular biological examples (protein folding, cellular membranes and water channels), which demonstrate how such interactions provide the bases for life.

Life based on water

“We made every living thing from water.” Anbiya 21:30

Thanks to its abundance on earth, water is easily accessible and inexpensive. However, in the summer of 1986, Professor Michael Levitt of Stanford University spent almost half a million dollars on a tiny amount of water, that would hardly wet the point of a pin. Certainly, the money was not spent on the water itself, but the expenditure (it now costs about 50 cents to run such a simulation) reflected the cost of running a simulation on a cluster of supercomputers for two weeks to understand the interaction between water molecules and a particular protein. Eventually, the money turned out to be well spent. Although the same protein had been modeled before by a research group at Harvard University in 1977, the simulation had been carried out as if the protein were in a vacuum. Levitt and his co-workers realized that the previous attempt to model the proteins in the absence of water was a poor predictor of the real-life scenario. Likewise, earlier DNA simulations meant to model the double helical DNA in the absence of water had failed, Levitt and his colleagues also succeeded in simulating the DNA by adding water in the environment, and the water molecules were found to be interacting with nearly every part of the DNA. Levitt’s groundbreaking discoveries not only revealed the importance of the interaction between water and biological molecules, but also paved the way for computational biologists to simulate biological entities in the presence of their native watery media.

When a drop of oil is placed in water, it does not mix with water. Hence, oil and water are said to be immiscible. In contrast, sugar easily dissolves in water and forms a homogenous mixture upon mixing. Although not as obvious at first sight, the underlying principles which govern this phenomenon can explain how water can interact with biological molecules.

Materials can be classified according to their “water tendency”: the ones that tend to avoid water (e.g. oil), are considered hydro-phobic (hydro: “water,” phobic: “fearing”), whereas materials that mix well with water (e.g. alcohol) are called hydro-philic (or water-loving). Water’s particular molecular structure turns out to yield a non-uniform electron distribution, and thus makes water molecule highly “polar” (see Figure 1.a). As a consequence, polar or charged molecules prefer being close to water molecules, whereas the apolar or neutral ones tend to avoid them.

Many curious aspects of water stem from another fact-that water molecules can interact with each other through “hydrogen bonding” (see Figure 1b). Although the molecules in a liquid are highly disordered, hydrogen bonding gives water molecules some order even in the liquid phase. A molecule’s ability to cooperate in hydrogen bonding is very important for breaking (or formation) of hydrogen bonds, and affect two parameters (i.e. the “order” and the “energy”) of the system which determine the feasibility of a certain chemical reaction.

Actually, most, if not all, of the oddities of water are due to these two properties (water-tendency and hydrogen bonding). Furthermore, these two aspects determine a great deal of how water interacts with other molecules, and the way water enables the proliferation of life. We will now elaborate on some biological phenomena and try to understand them in the light of these aspects of water.

Protein folding

Proteins are biological molecules that carry out the vital tasks of life. In the cell, proteins are initially synthesized as linear chains of amino acids ranging in size from a few to several thousand amino acids in length. Subsequent to synthesis, a linear chain spontaneously folds into a particular three-dimensional (3D) form (see Figure 2). This precise fold is essential for the execution of protein’s specific function (see Figure 3). As simple as it may sound, protein folding is currently one of the biggest questions in biophysics.

Researchers are working hard to be able to devise principles to estimate which 3D fold a certain linear amino acid sequence adopts, and what functions the eventual 3D structures execute. Although these questions related to the protein folding phenomenon are still far from being totally understood, some clues have been discovered.

In 1969 Cryus Levinthal stated that an average size protein would fold within about 1030 times longer than the expected lifetime of the universe if it were to fold via sampling all possible conformations even if the conformational sampling is very fast (e.g. a millionth of a millionth of a second for each conformation). This obviously is not what happens in reality, and the experimentally observed folding times are within milliseconds (a thousandth of a second) – second regime. This discrepancy between the estimated and the measured timescales is referred to as the “Levinthal Paradox.”

Consequently, proteins cannot rely on randomly sampling all the possible conformations to fold, but the folding must rather be a driven and directed process. Scientists hypothesize that water comes to the rescue at this point. As the linear protein chain is being synthesized, water-hating amino acids try to bury themselves away from water as soon as possible. This leads to the rapid collapse of the linear amino acid chain into a compact structure where hydrophobic regions are protected from water (see Figure 2c). This initial compaction which is provided by the interaction with the ambient aqueous medium is thought to be the key step in achieving folding within reasonable timescales. After the first rapid compaction, the protein adapts its final structure by sampling a much smaller number of possible conformations.

Simultaneously, hydrogen bonding helps the stabilization of certain folds with respect to other possible structures and contributes to the folding process. Eventually, the functional 3D fold is thus realized from the nascent linear protein chain.

Cellular compartmentalization

“He has let flow forth the two large bodies of water, they meet together, (but) between them is a barrier, which they do not transgress (and so they do not merge).” (Rahman 55:19-20)

Compartmentalization is an important feature of life. First of all, the boundary of a cell must be well-defined and well-controlled. Secondly, different tasks are carried out by specialized compartments (so called organelles) within most of the cells. The major design principle of the cellular boundaries depends on the immiscibility of water and oil. The subunits of cellular membranes are “lipids” which simply are oil-based molecules. A lipid molecule has two parts: A water-loving “headgroup” and two water-fearing “tails”. Because of the dual water-tendency of lipids, they can self assemble into bi-layers (see Figure 4 a and b), which eventually form enclosed structures. Thanks to the properties of water, this compartmentalization is readily achieved.

The cell membrane thus formed is impermeable to ions, and many chemical agents important for sustaining the cellular functions. Although such a barrier is essential for holding the cell contents as well as maintaining intracellular balance, material exchange between inside and outside of the cell is also an indispensible trait for carrying out the vast majority of vital processes (nerve impulse formation and transmission, cell signaling, nutrition, etc.). In order to achieve well-controlled material transport across the membrane, the cell membrane is decorated with various proteins that function as “channels” (see Figure 4c). These channel proteins come in different flavors and show specificity towards different chemicals. For instance, the channel protein for the potassium ion (K+) only allows the passage of potassium ions, whereas the sodium channel only lets sodium (Na+) through. Other channels have “gating” mechanisms that enable the channel to be “open” or “closed” depending on the need for the transport to happen. Although the specificity and gating mechanism of every channel protein relies on a unique ingenious design principle which deserves detailed mention in its own right, in the rest of the article we will focus on the water channel, for it once again exemplifies the perfect harmony between water and the bio-molecules.

Aquaporin: The water channel

Almost 170 liters of water is recycled in the human kidney on a daily basis, and this requires that kidney tissue possesses high water permeability. Since water cannot diffuse in and out of the cell membrane very rapidly for the reasons given above, reconciliation of the enormous daily flux of water in the kidneys has been a long-standing puzzle. The discovery of water channels (also known as “aquaporin”) by Peter Agre in 1992 resolved the mystery, and this finding was awarded the Nobel Prize in Chemistry in 2003. It is now known that the recycling machinery in the kidney chiefly consists of millions of aquaporins. Like other channel proteins, aquaporins also display selectivity: water is effectively transported across aquaporins, whereas the passage of other ions and miscellaneous agents is not permitted.

However, how this selectivity is achieved presented another riddle: Hydrogen is smaller than water and can move through the smallest opening. How, then, is the hydrogen selected against, while water is allowed? It was also well known that water molecules which are ordered within the channel constriction (see Figure 5) normally form a “proton wire” through which the hydrogen ions (i.e. protons) can easily flow just like an electrical current flows along an electrical wire. Thus, as water is transported across aquaporins, hydrogen ions should in principle move rapidly in and out of the cells through the chain of ordered water molecules (i.e. the proton wire) in an uncontrollable manner. This would cause an imbalance in the cellular environment, and most likely would lead to cell death.

The answer came from a computer simulation of aquaporin by Emad Tajkhorshid and Klaus Schulten at the University of Illinois at Urbana Champaign. They found that the water molecules change their orientation (see Figure 5) as they spun through the water channel. This rotation was achieved via water molecules’ specific interactions with the amino acid residues in the channel. Thanks to this orientation, the formation of the proton wire is disrupted (just like a break in an electric circuit) and the hydrogen ions are not permitted through the channel, while rapid water diffusion takes place. The interaction between water and aquaporin thus provides just another reason water is rightfully considered the cradle of life.

Conclusion

“There are only two ways to live your life. One is as though nothing is a miracle. The other is as though everything is a miracle.” Albert Einstein

… and that He sends down water from the sky, and revives with it the earth after its death. Surely in this are signs for people who will reason and understand. Rum 30:24 

References

1. Gedik, N. “The Miracles of Water,” The Fountain, Issue 43, January–March 2005.

2. Ileri, R. “Water and Vitality,” The Fountain, Issue 2, April-June 1993.

3. Unal, Ali. The Qur’an: An Annotated Interpretation in Modern English, The Light, Inc. NJ: 2005.

4. “Simulating Water and The Molecules of Life,” Scientific American, November 1998.

5. Errington, J. R. & Debenedetti, “P.G.” Nature, 409, 318–321, 2001.

6. Water, Wikipedia.

7. “Mysteries of Water,” Physics Today, June 2003.

8. Sener, Hamdi. “Mikroalemdeki Canli Motorlar” (Living Engines in the Micro World), Sizinti, September 2005.

9. Figures are modified from: Chemical polarity, Wikipedia
Hydrogen bond, Wikipedia
http://www.ccl.net/cca/documents/dyoung/water/
http://www.helsinki.fi/~jtvaara/images/water.gif
“Inner Life of The Cell” animation, http://multimedia.mcb.harvard.edu/
“Molecular Biology of the Cell,” 4th Edition; Bruce Alberts et al.
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Enviromnental damage ramains a growing concern. Despite rigorous energy efficiency programs and research and development (R&D) efforts on cleaner energy technologies in most developed countries, no developing country views these as priorities. And they have a case: Developed countries, which enjoyed high economic growth for decades by ignoring the environmental consequences, are hindering developing countries’ economic growth. On the other hand, representatives from developed countries say that we are all in the same boat and will sink together if developing countries do not pay attention to environmental consequences.

In December 1997, world leaders gathered in Kyoto to address the problem of global warming and to decide which countries should cut emissions and to what extent. Not surprisingly, developing countries objected to any restriction that might limit their economic growth. Such discussions will become more intense in the aftermath of the Kyoto Protocol.

This article will not address the issue of environmental reparations. Rather, it will discuss the energy markets’ current situation and short-term future trends.

Basic Properties of the Energy Systems

Present-day energy systems have several basic characteristics. All policy makers dealing with energy systems should know these basics by heart.

First, energy systems develop slowly because they require significant capital and infrastructure that can be replaced only gradually. There are two important consequences resulting from this fact:

•Intense capital requirements are a strong barrier to average-sized firms. Thus, energy systems are seldom run by private enterprises. In most countries they are constructed and run by the state, and a separate government body deals with energy issues. Energy systems have been dominated by heavy regulations even in most market-oriented economies. The recent trend of deregulation is an exception rather than the norm.

•Even if a state realizes that current energy systems can be improved significantly (e.g., switching to other fuel types or deregulating the market), making changes to a huge, functioning infrastructure is a slow and painful process. It is relatively easy to make changes during the initial stages of an energy system. But as time passes, this becomes more difficult.

As in most cases, good planning is essential. A state must be very careful when building its energy systems, and should pay attention to underlying energy market trends. Important lessons can be learned from the long history of mistakes committed by developing countries. And if a developing country fails to keep up with recent trends, it may find itself trapped by its own hands in an inherently inefficient system for decades.

Second, energy systems are heavily reliant on fossil fuels. Historically, coal has been a prominent energy resource in most countries. Despite its widely acknowledged negative impact on human health and the environment, it still dominates energy systems in such developing countries as India and China. In most countries, oil is the primary energy source.

Oil was one of the most influential key factors of the twentieth century. Just by looking at the traffic on our teeming highways or the modern political landscape, we can understand how profoundly oil has changed the way we live and handle international politics. In the light of the oil crises of 1973 and 1980, the reverse-shock of 1986, and another crisis during the Gulf War of 1990, the need to diversify away from oil becomes abundantly clear.

Environmental concerns also support the case against oil. This is how natural gas, a slightly cleaner fossil fuel, gradually entered the picture. Given the current energy systems’ dependence on these fossil fuels and the fact that energy systems change slowly, oil, coal and natural gas will continue to be dominant for years.

Third, the driving force behind the dynamic of switching from one fuel type to another is economics. Fuel types with smaller unit costs survive in the long run. Oil, for example, now has the lowest unit cost (cost per unit of energy) in most regions of the world.1

Given this, cleaner fuel (e.g., solar energy) still have a long way to go before becoming economically viable. Why would you pay $5 for what you can get for $3? Countries that use non-oil energy resources do this for a number of reasons, such as they do not have natural resources and so transporting oil ends up costing more, or they have abundant natural energy resources of other types. But, in general, economics is the most important issue here.

Introducing New Fuels

What trajectory does the unit cost follow when a new fuel is introduced? Consider photovoltaic (PV) cells. The term photovoltaic refers to a family of technologies that convert light directly into electricity. PV technology is an appealing alternative-it is a renewable, environmentally benign, and domestically secure energy source. It is modular and can be scaled up to meet demand.2 However, unit cost is currently high compared to fossil fuels.

A new technology’s unit cost is believed to follow a learning (or experience) curve as a function of installed capacity. As shown in Figure 1, technologies may experience declining costs due to their increasing adoption by society. This decline may be attributed to several factors:

• Technology innovation and manufacturing improvements: Costs may decline due to a better understanding of the underlying science, progress in related fields, or via learning by doing as well as learning by using.

• Economies of scale: Unit cost is a function of total production. Products produced in large quantities have lower unit costs. Most new fuel types have high unit costs, and demand is too low to encourage large-scale production. It almost seems paradoxical. But there are ways to break this cycle. Regulations encouraging usage of new fuel types may be enforced, consumers who have priorities other than cost may be targeted to expand the current market, or the cost may drop low enough for the technology to become attractive even for low production levels.

In achieving economies of scale, consumer demand should he considered. A major concern for the end-use consumer is convenience. The value of oil would be much lower if gas stations were not located all over the country. The same issue applies to fuel cells and electric cars. They will not be as convenient as conventional cars until the proper infrastructure exists.

Since 1960s, cooperative investments by manufacturers and governments have resulted in the accumulation of experience within the solar industry and the subsequent cost reduction of PV systems. Significant cost reductions have occurred in both the PV modules that house the solar cells, and the ancillary components (known as balance-of-system). Between 1968 and 1998, the global cumulative installed capacity of PV modules doubled more than thirteen times, from 95 kW to 950 MW, while costs ($/Wp) were reduced by an average of 20.2% for each doubling.4

Trends for Different Fuel Types

After this overview of energy systems, lets look at the trends for specific fuel types. Figure 2 is taken from International Energy Outlook 2000 (IEO2000), an annual report published by the U.S. Energy Information Administration (EIA).5 It displays projections of energy usage by fuel type up to 2020. The highlights following the figure are summarized from the reports contents.

Coal: Carbon dioxide is a very effective greenhouse gas and contributes significantly to global warming. Since coal is the most carbon-intensive fuel, global climate change debates focus on reducing its use. Coal use also has significant public health consequences, due to particulate matter emissions. Historically, coal has been a major source of energy. Although it has lost market share to petroleum products, natural gas, and nuclear power in the last decades, it remains a key source of energy, especially for generating electricity. In the IEO2000 reference case, coals share of total energy consumption falls only slightly, from 24 percent in 1997 to 22 percent in 2020 (Figure 3). Its historical share is nearly maintained, because large increases in energy use are projected for developing Asian countries, where coal continues to dominate many national fuel markets. China and India are projected to account for 97 percent of the worlds total increase in coal use.

Oil: Oil use will grow in absolute terms, but even optimistic oil supply scenarios predict that its share in the fuel mix will decline gradually. Despite efforts to reduce reliance on Middle Eastern oil, as well as advances in technical capability, new oil reserves are not compensating for depleted ones. The experts estimates of vast oil reserves in the Caspian and Tarim basins proved to be somewhat high, and the latest probes have been partially disappointing. According to EIA estimates, the share of the Persian Culf supplies is likely to increase in the coming years. Economic theory says that prices rise as supply declines. Oil prices have been quite volatile and can be expected to remain so in the future, principally as the result of unforeseen political and social circumstances. Without attempting to predict any crisis, the IEO2000 forecast shows a gradual rise in world oil prices. Oil currently provides a larger share of world energy consumption than any other energy source and is expected to remain in that position throughout the forecast period. Its share of total energy consumption declines slightly, however, from 39 percent in 1997 to 38 percent in 2020, as countries in many parts of the world switch to natural gas and other fuels, particularly for electricity generation. World oil consumption is projected to increase by 1.9 percent annually over projection period. Most of the growth in oil use is projected for the transportation sector, where few alternatives are currently economical.

Natural Gas: Natural gas remains the fastest growing component of global energy consumption. Over the IEO2000 forecast period, its use is projected to more than double in the reference case, reaching 167 trillion cubic feet. The natural gas share of total energy consumption increases from 22 percent in 1997 to 29 percent in 2020. It also accounts for the largest increment in electricity generation. Combined-cycle gas turbine power plants offer some of the highest commercially available plant efficiencies, and natural gas is environmentally attractive because it emits less sulfur dioxide, carbon dioxide, and particulate matter than either oil or coal.

World Energy Consumption Shares Type: 1970-2000

In the industrialized world, natural gas consumption has the largest projected increase among the major fuels, increasingly becoming the choice for new power generation because of its environmental and economic advantages. Its incremental use in developing countries is expected to supply both power generation and other uses, such as town gas and fuel for industry. Despite concerns about the extent of natural gas reserves worldwide, current proven reserves suffice for this markets steady development without a substantial price increase.

Nuclear Power: The prospects for nuclear power are uncertain, despite a projected growth rate of 2.5 percent per year in total electricty demand through 2020. In the IEO2000 reference case, global nuclear capacity is projected to increase to 368 gigawatts in 2010 and then gradually fall to 303 gigawatts in 2020. Aggressive plans to expand nuclear capacity, mainly in Asia, lead to a near-term increase. However, plant retirements in America and other countries exceed total new additions worldwide, and produce a decline later in the forecast. The International Institute for Applied Systems Analysis [IIASA] is one of the authorities on energy issues.

IIASA projections [which extend until 2100] hold a slightly pessimistic view of nuclear energy. Nuclear energy production has stagnated for several decades, and IIASA suggests that this will continue. Currently, nuclear energy is prominent in only a handful of countries. Not many nuclear plants are being built, and existing ones are being dismantled. With large up-front capital costs, plant safety, and recycling nuclear material after dismantling issues, this option is becoming less and less attractive. Public opposition, already strong in the US and Europe, is growing in Asia. Nuclear safety issues moved to the forefront in Asia in 1999 after several leaks at nuclear power plants in South Korea and China, and the serious accident in a reprocessing facility in Tokaimura, Japan. Such events are likely to raise concerns about Asias aggressive plans for nuclear capacity expansion. IIASA predicts that if a safer and cheaper new generatinn of nuclear plants is introduced, nuclear powers ultimate share in fuel mix will grow. Otherwise, it eventually will come to an end.

Renewables: The development of renewable resources is constrained in the IEO2000 reference case projections by expectations that fossil fuel prices will remain relatively low, and that, as a result, renewables will have a difficult time competing. Failing a strong global commitment to environmental programs, such as the limitation and reduction of greenhouse gases outlined in the Kyotu Protocol, it is difficult to foresee significant and widespread increases in renewable energy use. Modest growth in renewabte energy is projected to continue, maintaining an 8 percent share of total energy consumption. Nevertheless, in the long run, as other fossil fuel types become more expensive due to depletion and R&D efforts push the unit cost further down, new opportunities will emerge. Even conservative estimates predict that the worlds energy will rely considerably on renewables before 2100.7

Conclusion

In this article,we highlighted several basic characteristics of energy systems, and drew attention to some underlying trends for particular fuel types. Based on this information, we can say that:Energy systems are capital-intensive and hard to change once they have been built. Therefore, developing countries should track energy system trends closely and build their energy systems according to their future needs. The most important factor influencing the decision of which energy source to use is economics. Until a resources unit cost is competitive with others, it will not enjoy widespread acceptance and usage. Fossil fuels will dominate energy markets in the short run. The shares of coal and oil in the fuel mix will remain relatively constant until 2020, while the market for natural gas will expand rapidly. Nuclear power will survive only if a new generation of safer and cheaper reactors is introduced. Renewables will be the ultimate choice of the future. Currently, however, they cannot compete successfully on cost with conventional fuels.

Footnotes

1. Although the cost of extraction rises as the amount of oil remaining underground decreases, extraction technology also advances and pushes the cost down. Transporting oil from the field to the marketplace is added to the extraction (or purchasing) cost.
2. Christopher Harmon, Experience Curves of Photovoltaic Technology (March 2000). The entire report is available on IIASA web site: http: www.iiasa.ac.at/Publications/Documents lR-00-014.pdf
3. Netherlands Energy Research Foundation (ECN at Petten), “Endogenous Technological Change in Energy System Models.” Paper presented at the 1999 IIASA conference.
4. IIASA-WEC. 1998.
5. International Energy Outlook 2000 is available on the EIAs Web site: http: www.eia.doe.gov/oiaf/ieo/index.html.
6. N. Nakicenovic, A. Gruebler, and A. McDonald, Global Energy Perspectives (Cambridge. UK: 1998).
7. Experts differ over what exactly is included in this category. For practical purposes, renewables cover all energy sources except coal, oil, natural gas, and nuclear. Therefore this group includes, but is not limited to, hydroelectricity, wave, wind, biomass, and solar energy.

THE CASPIAN PIPELINE DECISION

After the break-up of the Soviet Union and the emergence of independent states, the Caspian region has become a magnet of interest for different powers, including China, Russia, Turkey, Iran, and the United States. Five states border the Caspian Sea: Russia, Azerbaijan, Kazakhstan, Turkmenistan, and Iran. Kazakhstan and Azerbaijan have vast oil resources around the Caspian Sea, while Turkmenistan has significant natural gas reserves. However, as the region is landlocked, pipelines have to be constructed to transfer these resources to external markets. Since these three states have neither the expertise nor the financial resources for oil exploration, extraction, and transfer, they have to rely on foreign investment. After the pipeline is in place, the cash flow generated by oil and gas exports will be of great importance in the economic development of these states.

But not so fast. The situation has proven to be a very complex one involving the status of the Caspian Sea, regional disputes, and the conflicting economic and political interests of the countries involved. Due to the complexity of the decision and the billions of dollars at stake, the Azerbaijan International Operating Company’s (AIOC) feasibility report was delayed three times last year, which also delayed any decision of the final pipeline route.’1 This article investigates some of the issues surrounding the Caspian oil pipeline debate.

RESERVES

First, just how much oil is lying under the Caspian Basin? Early estimates of around 200 billion barrels predicted that the region would be another Persian Gulf.2 However, exploratory oil wells turned out to be disappointing. A conservative study by the James Baker Institute estimates proven reserves at 15 to 30 billion barrels.3 On the other hand, some experts argue that these numbers are misleadingly low. A reasonable estimate would be somewhere between 60 and 100 billion barrels. More than half of these reserves lies under Kazakhstan, and most of the rest lie elsewhere.4

Two main oil pipelines will be built and brought on line to serve the region up to 2010. At the present time, the only pipeline that has reached the final stages of negotiation is the Caspian Pipeline Consortium (CPC) pipeline for oil from Kazakhstan to the Russian port of Novorossysk.5 After this, the decision concerning the main oil export pipeline route from Baku (Azerbaijan) to a port, from where the oil will be transferred to external markets by tankers, gets complicated. There are competing proposals for this route from Baku, which include6:

• Novorossysk: To the north, a main oil export pipeline across Daghestan and Chechnya to Russia’s port of Novorossysk.

• China: To the east, there is a proposal to build an oil pipeline from eastern Kazakhstan’s Uzen field to western China as part of an overall $9.5 billion deal supported by CNPC, China’s state oil company CNPC.

• Supsa: To the north again, this route links Baku to Supsa, a Georgian port on Black Sea.

• Ceyhan: To the west, oil pipelines transiting from Baku to Ceyhan with links to cross-Caspian lines from oil and gas fields in Kazakhstan and Turkmenistan. The route originates in Baku, enters Georgia, and reaches the southern Turkish Mediterranean port of Ceyhan through eastern Turkey.

• Iran: To the south, an oil pipeline from the Caspian states across Iran, to a new port on the Gulf of Oman. Shipping oil by tankers or another alternative from Tabriz to Ceyhan has also been proposed by Iran.

All of these pipeline options are technically possible; most are commercially feasible at some volume. We now turn to the specifics of those routes.

THE ALTERNATIVES

China: This route has not been considered seriously by either the states or the companies. First of all, Chinese companies cannot provide competitive deals, possibly due to the recent economic recession. Second, the pipeline will be much longer and more expensive than the other alternatives. Third, China is primarily linked with Kazakhstan, and for transferring oil from Azerbaijan to Kazakhstan (or directly to China) some real challenges remain: the pipeline has to pass either under the Caspian Sea (which is itself highly questionable, given the debate over the Caspian Sea’s status) or pass through disputed territories. Fourth, Asian markets are not the best place to export oil, since European markets will probably pay more.7

Supsa: For early oil, TEKFEN (a Turkish construction company) began construction of a 380 km. pipeline from Baku to Supsa. But as this pipeline, completed and opened in April 1999, will not be sufficient for the main export, a larger one along the same route should be built. Should this route be chosen, it will be the shortest route and, not surprisingly, the cheapest. Its price tag is $1.2 billion.8 The construction cost may be lower if the pipeline passes trough Armenia, rather than going around it. However, the long-lasting conflict between Azerbaijan and Armenia makes this unlikely.

On the other hand, Georgia is not an ideal pipeline-transit country. Since achieving its independence in 1991, numerous territorial conflicts and separatist movements have taken place, all of which increase the risk of pipeline sabotage and other political risks. Russia currently supplies military support to Abkhazia in its independence struggle against the Georgian government.9 With the reestablishment of Russia’s extensive military basing rights in Georgia, the support apparently ceased, but most experts argue that Russia is still supporting, either directly or tacitly, regional instability to block pipeline alternatives through Georgia and to promote its own route (Novorossisk).

Another problem with the Supsa route relates to the Bosphorous Straits of Turkey. According to the 1936 Montreux Convention, tanker passage through the Straits is free. However, Turkey points to tightening political and physical constraints, as well as sharply increasing tanker accidents threatening the environment in Istanbul,’10 its most populated city. Turkey can certainly make the passage extremely difficult for tankers within the convention, by requiring extensive precautionary measures and removing their passage priority, causing tankers to wait for days before passing through the Straits. Most experts argue that Turkey is using the straits as a political lever to promote its own route (Ceyhan). But still, this uncertainty adds another variable to the calculation of pipeline companies.

Novorossisk: The 452 km. pipeline,11 which is estimated to cost $2 billion,12 starts at Baku, reaches the Russian Black Sea port of Novorossisk across Daghestan and Chechnya. Although cheap, this pipeline still faces the Straits problem mentioned above.

Although avoiding Georgia, this route has its own problems. Disagreements on distributing transit fees between Russia’s central and regional authorities may hinder negotiations. Russia does not have a particularly bright history regarding pipeline management. Moreover, the transfer may be subject to frequent disruptions due to instability in the north Caucasus. If Russia decides to bypass Chechnyian territories by an extension through Daghestan, there will be an added risk of pipeline sabotage by the Chechens.13 All these, when added to overcrowded port facilities and poor weather conditions at Novorossisk, make this route even less attractive.

Furthermore, there are political and economic factors to consider. From an influence point of view, most Central Asian republics have been under Russian influence for centuries. They still have economic, cultural, and military ties with Russia, which is anxious to maintain its influence in these republics for both security and economic reasons. Those republics dependent on Russia will pose much less danger, not to mention benefits from economic relations. On the other hand, the Central Asian republics want to be less and less dependent on Russia and discover their own identity by stepping out of the shadow of a now-defunct empire. Not surprisingly, the Azerbaijan government has expressed its reluctance concerning the Novorossisk route more than once. From a strategic point of view, Russia wants to keep her monopoly for oil transfer in the region so that it can be used as a strategic lever in the future. Economically, transit fees will be more than welcome in an economically depressed Russia. Furthermore, Russia will be able to purchase at lower rates than those in the international markets.

Ceyhan: The total length will be approximately 1,730 km (468 km in Azerbaijan, 225 km in Georgia, and 1,037 km in Turkey14). It is also an expensive alternative; estimates place its total cost at around $3 billion. The latest feasibility study, undertaken by a German company, put a price tag of $2.3 billion.15 The oil will serve to offset Turkey’s energy shortages, as well as giving it the economic advantage of transit fees.

The Ceyhan route has been favored by Azerbaijan, which wants to avoid giving Russia any influence over its resources. Azerbaijan is also seeking to avoid the proliferation of political Islam (from Iran) in Azerbaijan, thus undermining the possibility of an Iranian route. As for the Supsa route, it has the same Straits problem mentioned above. Thus, President Haydar Aliyev has repeatedly and publicly expressed his willingness for the Ceyhan route.14 However, his final decision will depend on the AIOC’s feasibility report. It is therefore considered unlikely that he will insist on Ceyhan route, if companies find the Ceyhan route to be economically less attractive. After all, the companies and not Azerbaijan are going to pay for the construction. The final route decision therefore will be a joint decision of the AIOC and President Aliyev.

The United States has also been publicly favoring the Ceyhan route.16 The reasoning is as follows:

• The pipeline goes directly into the Mediterranean Sea, thus avoiding straits and the Persian Gulf. This will serve to of the supply of energy, which is an American goal. So far, a significant number of major fields lie in the Persian Gulf; unfortunately, the United States does not have the best of relations with some of the states in that region. Russia already has control over Kazakh oil and it would be unwise to leave Azeri oil to the Russian monopoly.

• Turkey has been the United States’ ally in the region for a long time, and is closer to United States than Russia and Iran.

• As a democratic country and a supporter of free-market economies, Turkey’s influence on the Central Asian republics would be much more positive than that of Russia and Iran. The proliferation of Iranian-style political Islam may be particularly dangerous, whereas Turkey’s secular version of Islam is much more preferred, according to the Clinton administration.

From a security viewpoint, the Turkish Army has been securing eastern Anatolia since 1998 against the activities of the Kurdish terrorist organization PKK. The organization’s leader Abdullah Ocalan was recently captured in Kenya, which has considerably improved the prospects for regional security. On the other hand, Georgia’s problem with instability is also valid for Ceyhan.

Iran: Iran has proposed several routes. In general, those routes are less expensive than Ceyhan but more expensive than the other alternatives. There are no acute instabilities in the region. However, American sanctions directly affect Caspian pipeline development in Iran, notably through the Iran-Libya Sanctions Act (ILSA). The goal of the 1996 law is to press for a change in Iran’s foreign policy, which was widely criticized as being supportive of terrorism and weapons proliferation as well as undermining the Middle East peace process. In practical terms, the ILSA prohibits direct foreign investment in Iran’s energy capability and infrastructure, and applies to America business as well as third parties.17

The United States remains strongly opposed to an Iranian route. As mentioned, such a route is not in the best interest of Azerbaijan either, due to the concerns of Iranian-style political Islam.

CONCLUSION

In recognition of the growing stress on the Ceyhan route, Georgia has aligned with Turkey, Azerbaijan, and the United States to push for the Ceyhan alternative. On the other hand, Armenia has aligned with Russia and Iran to oppose the Ceyhan route (or for that matter, any route) that will benefit Azerbaijan (its enemy). The Armenian government argues that Azerbaijan will use the money from oil exports to increase its military build-up against Armenia. Iran and Russia are opposing the Ceyhan route, for rules out their own routes. As clearly seen, Russia, Armenia, and Iran have no common interest whatsoever, except blocking the Ceyhan route to promote their own conflicting interests.

On the other hand, companies are in an awkward situation. The United States and Azerbaijan are increasing their political power on the companies for the Ceyhan route, whereas companies find this route more expensive when compared to other options. They also argue that current proven oil reserves do not justify the construction of such an expensive pipeline. They say that the oil found may never be able to fill the pipeline. Another factor is that oil prices are at their lowest level in 20 years. The expenses will not be justified unless oil export profits justify the main export pipeline expenses. Thus, they are playing a wait-and-see game, to see whether more oil will be found or whether oil prices will increase. The debates around the Caspian pipeline are likely to continue next year, and a win-win deal involving all the Caspian states seems nowhere near.

FOOTNOTES

1. David Filipov, “Caspian Port’s Oil Gush Trickling,” Boston Globe, 10 February 1999, sec. A, p. 1.
2. R. E. Manning and J. A. Meyers, “Dream of Oil Drives Diplomacy,” Los Angeles Times, 1 November 1998, sec. M, p. 2.
3. The James A. Baker III Institute for Public Policy, “Unlocking the Assets: Energy, and the Future of Central Asia and the Caucasus. A Political, Economic and Cultural Analysis,” Rice University Research Report (April 1998): 1.
4. The Energy Information Administration, “International Energy Outlook: 1998,” Research Report (1998): 34. http://www.eia.doe.gov/oiaf/ieo98/home.html
5. Heslin, S., Key Constraints to Caspian Pipeline Development: Status, Significance and Outlook. Research Report for The James A. Baker III Institute for Public Policy, Rice University (1998): 4.
6. Ibid., 4, 5.
7. The James A. Baker III Institute for Public Policy, “Unlocking the Assets,” 3.
8. http://www.gasandoil.com/goc/contract/cox7l803.htm
9. H. Cemal, “Petrol Cografyasinda Yeni Kavsak Noktasi Turkiye,” Sabah Turkish Daily Newspaper, 3 October 1998.
10. Heslin, Key Constraints to Caspian Pipeline Development, 16.
11. “Kazakhstan Approves an Oil Pipeline Study,” Journal of Commerce, 30 October 1998, sec. A, p. 10.
12. Cemal, “Petrol Cografyasinda Yeni Kavsak Noktasi Turkiye.”
13. Heslin, Key Constraints to Caspian Pipeline Development, 7.
14. “Five Nations Endorse Caspian Oil Pipeline,” San Francisco Chronicle, 30 October 1998, sec. A, p. 14.
15. “Baku Ceyhan’a bir adim daha,” Yeni Yuzyil Turkish Daily Newspaper, 7 July 1998.
16. “Four Former Soviet Republics Join Turkey on Pipeline,” The Orlando Sentinel, 30 October 1998, sec. A, p. 20.
17. “U.S. Has Impact on Pipeline Route from Caspian Sea,’ Wall Street Journal, 30 October 1998, sec. A, p. 17.
18. Heslin, Key Constraints to Caspian Pipeline Development, 17-19.

American Indians applied its leaves as a poultice to heal wounds, and brewed a cough mixture from its roots. Now its seeds are claimed to have medicinal uses ranging from relieving pre-menstrual syndrome to management of multiple sclerosis, alcoholism and atopic eczema.

The seeds contain approximately 15% protein, 24% oil and 43% cellulose and lignin. The fatty acids in the oil are thought to be important to health because the oil contains 65-85% linoleic acid (LA) and 7-15% gamma linoleic acid (GLA): LA is an essential fatty acid for the body which it cannot make but which it converts to GLA. GLA is one of the components of cells and a precursor of prostaglandins which regulate many body functions. However, the LA GLA conversion step may be blocked by a range of factors including excessive levels of blood cholesterol, a high proportion of certain fatty acids in the diet, ageing, alcohol intake and diabetes.

Supplementing the diet with evening primrose oil (EPO) by-passes the conversion step, thus providing for the presence of GLA in the body. A recent World Health Organisation report suggested that 3% of the total calorific intake of adults should be in the form of essential fatty acids, this figure rising to 5-6% for children and pregnant and lactating women. GLA can be provided by several other sources as well, e.g. borage oil and blackcurrant oil, both of which contain a higher concentration of GLA than EPO but not as much LA.

The quality and composition of EPO used in commercial manufacturing is currently the subject of much research and monitoring work. In the UK research is concentrated on obtaining GLA from other sources e.g. by fermentation from the fungus mucor javanicus.

A concentrated oil from evening primrose, borage and blackcurrant seeds, is now undergoing clinical trials and may be used in second generation oil products of the future. EPO is already used in a variety of beauty and hygiene products, including cosmetic and skin care products, shampoos and soaps.

Trials have been curried out to investigate claims of the effectiveness of EPO in treating many diseases and conditions, including multiple sclerosis, cardiovascular disease, asthma, atopic eczema, cancer, obesity and premenstrual syndrome. So far the results have been variable but some genuine clinical effects have been seen.

Millions of dollars have been and are being spent on developing new methods of extracting useful natural products for the benefit of mankind. We are now seeing a widespread desire to return to natural resources to cure various ailments. Let us hope that, before mankind destroy their environment, they will come to realize the importance of nature’s medicine-cabinet, and give thanks where it is due. Without that giving of thanks, mankind will not practise the humility and compassion necessary if our common resources are to be preserved both for ourselves and for future generations.