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	<title>pen &#8211; Fountain Magazine</title>
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		<title>“Pen” diagnoses cancer in 10 seconds</title>
		<link>https://fountainmagazine.com/all-issues/2017/issue-119-september-october-2017/pen-diagnoses-cancer-in-10-seconds/</link>
		
		<dc:creator><![CDATA[The Fountain]]></dc:creator>
		<pubDate>Fri, 01 Sep 2017 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 119 (September - October 2017)]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[Cancer detection]]></category>
		<category><![CDATA[MasSpec Pen]]></category>
		<category><![CDATA[pen]]></category>
		<category><![CDATA[Science Square]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2017/issue-119-september-october-2017/pen-diagnoses-cancer-in-10-seconds/</guid>

					<description><![CDATA[A team of engineers and scientists has developed a “pen” that accurately identifies cancerous tissues during surgery within 10 seconds. This handheld instrument could one day be used by surgeons to quickly determine what tissue to cut and preserve. The instrument, called MasSpec Pen, was tested on tissue from 253 patients and found to distinguish [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>A team of engineers and scientists has developed a “pen” that accurately identifies cancerous tissues during surgery within 10 seconds. This handheld instrument could one day be used by surgeons to quickly determine what tissue to cut and preserve. The instrument, called MasSpec Pen, was tested on tissue from 253 patients and found to distinguish between cancerous and healthy tissue with ~ 96% accuracy. When a patient undergoes surgery to get rid of a tumor, a surgeon tries to remove all cancerous tissue while preserving the healthy tissue. Although maximizing cancer removal is critical to improving patient survival, removing too much healthy tissue can also have profound negative consequences for patients. For example, breast cancer patients could experience higher risk of painful side effects and nerve damage. Thyroid cancer patients could lose speech ability or the ability to regulate the body’s calcium levels in ways that are important for muscle and nerve function. The current technology is called frozen section analysis, and it takes 20-30 minutes for a pathologist to prepare and analyze the sample. Because the metabolites in rapidly dividing cancer and normal cells are so different, MasSpec Pen extracts molecules from the patient’s tissue with a tiny amount of water and then sends them through tubes to an instrument that can identify the molecular fingerprint of cancer. When the analysis is complete, the words “Normal” or “Cancer” automatically appears on a computer screen. For certain cancers, such as lung cancer, the name of a subtype can also be predicted. MasSpec Pen seems to be a big improvement on current methods, and the researchers hope to start testing it during oncologic surgeries in 2018.</p>
<ul>
<li>Zhang J et al. Nondestructive tissue analysis for ex vivo and in vivo cancer diagnosis using a handheld mass spectrometry system. Science Translational Medicine, September 2017</li>
</ul>
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		<item>
		<title>By the Pen</title>
		<link>https://fountainmagazine.com/all-issues/2014/issue-102-november-december-2014/by-the-pen-november-2014/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sat, 01 Nov 2014 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 102 (November - December 2014)]]></category>
		<category><![CDATA[eyes]]></category>
		<category><![CDATA[forehead]]></category>
		<category><![CDATA[ink]]></category>
		<category><![CDATA[inspiring]]></category>
		<category><![CDATA[Literature & Languages]]></category>
		<category><![CDATA[paper]]></category>
		<category><![CDATA[pen]]></category>
		<category><![CDATA[poem]]></category>
		<category><![CDATA[winds]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2014/issue-102-november-december-2014/by-the-pen-november-2014/</guid>

					<description><![CDATA[and the deeds that are not revealed yet,I am an ink without pen;I am a pen without ink,both without paper.I am all,I am neither;I do not knowanything other than things bestowed upon.By the Nunand whatever the pens cover,whatever the pens reveal Ink heals,Pen befriends.Paper mirrors,Words are interlocutor.They are lost indeedwhen you have no mirroring ear,when [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>and the deeds that are not revealed yet,<br />I am an ink without pen;<br />I am a pen without ink,<br />both without paper.<br />I am all,<br />I am neither;<br />I do not know<br />anything other than things bestowed upon.<br />By the Nun<br />and whatever the pens cover,<br />whatever the pens reveal</p>
<p>Ink heals,<br />Pen befriends.<br />Paper mirrors,<br />Words are interlocutor.<br />They are lost indeed<br />when you have no mirroring ear,<br />when the mirror is gone,<br />the paper torn; <br />to hear<br />makes the pen cry, and<br />only then ink is revealed.</p>
<p>O, Beloved Friend<br />Fill my hands with the ink<br />of your inspiring winds.<br />Let my eyes, right and left, see<br />none,<br />All You,<br />thus all. <br />Did you hear what happened?<br />Did you know how it happened?<br />Of course you do.<br />But I want to tell<br />because this is what you do:<br />you know, but again, the pleasure<br />is to listen.<br />And on my part<br />it is to tell.<br />I want to forget my forehead on the soil that stands before You, welcoming,<br />I want to forget nothing. <br />But I only become Zero<br />In that moment.</p>
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		<item>
		<title>In an Author&#8217;s Mind</title>
		<link>https://fountainmagazine.com/all-issues/2009/issue-68-march-april-2009/in-an-authors-mind/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sun, 01 Mar 2009 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 68 (March - April 2009)]]></category>
		<category><![CDATA[article]]></category>
		<category><![CDATA[farmer]]></category>
		<category><![CDATA[heart]]></category>
		<category><![CDATA[idea]]></category>
		<category><![CDATA[inspiration]]></category>
		<category><![CDATA[Literature & Languages]]></category>
		<category><![CDATA[mind]]></category>
		<category><![CDATA[pen]]></category>
		<category><![CDATA[rational]]></category>
		<category><![CDATA[reductionist]]></category>
		<category><![CDATA[regular]]></category>
		<category><![CDATA[romantic]]></category>
		<category><![CDATA[talk]]></category>
		<category><![CDATA[time]]></category>
		<category><![CDATA[turned]]></category>
		<category><![CDATA[words]]></category>
		<category><![CDATA[writer]]></category>
		<category><![CDATA[writing]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2009/issue-68-march-april-2009/in-an-authors-mind/</guid>

					<description><![CDATA[Rational, Romantic, and Regular were three roommates. They were all new writers with splendid ambitions. They all dreamt of displaying the best of their talents one day. For this, they had different styles and writing strategies. Rational, who had graduated from the school of science, always sought a sound reason for writing, and did not [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Rational, Romantic, and Regular were three roommates. They were all new writers with splendid ambitions. They all dreamt of displaying the best of their talents one day. For this, they had different styles and writing strategies. Rational, who had graduated from the school of science, always sought a sound reason for writing, and did not schedule a time for writing otherwise. Romantic, on the other hand, had not had any formal education. But she had been very well trained by her parents to become a keen observer both materially and spiritually. So, Romantic reserved ample time to wait for inspiration and to dress it in the most beautiful words whenever it came. Regular, a graduate of a military school, split his days into well-defined slots, and had a regular time for writing.</p>
<p><span id="more-1010"></span></p>
<p>Reductionist, their next-door neighbor, was editor-in-chief of a highly recognized magazine. He was kind of older, and so had rather a fatherly attitude toward them. Not surprisingly, each of the three writers had one thing in mind-to catch the attention of their next-door neighbor, which was a really tough job. Having seen thousands of different articles in his life, and still editing several of them every day, Reductionist had become very good at categorizing ideas and pieces of writing. So, it was really difficult, if not impossible, to come up with something that he would call original. This state of Reductionist caused competition, and sometimes jealous actions, among the three writers.</p>
<p>Reductionist used to invite his neighbors to accompany him whenever he was invited to a program related to writing. Rational especially liked them because he learned new things from different people. Romantic loved staying alone, but doing this in different settings opened ways for new inspiration. Regular, on the other hand, was not very thrilled at the idea of traveling because it disturbed his daily schedule. But he thought it was OK being with friends as part of a bigger schedule that spans a larger time.</p>
<p>At the end of one of those trips, they were traveling back home on a dark and rainy night. As they covered each mile of the road, they talked about various topics. After some random ones, they started talking about a topic that really interested all of them: writing. They discussed different issues surrounding the main idea of writing, such as how to start writing, how to write well, how to make your words carry meanings that would satisfy the mind and the heart, and so on. When it came to the issue of inspiration and new ideas, Romantic told a short story:</p>
<p>“A farmer had two fields. He started cultivating both. After the first season, he saw that one of the lands was yielding produce but the other one didn’t. Several consecutive trials only confirmed the quality of the fertile one. The more trials the farmer made, the faster he received the produce and the more he reaped. Then the farmer decided not to use the barren field anymore.</p>
<p>“The inspirations are gifts from God. He plants seeds in our hearts in that way. People who value and pay due respect to inspiration are like the fertile field in the story. The farmer enjoys the produce and uses that field more. People who ignore inspiration or postpone dealing with it are the barren land. They don’t foster the seed, and the farmer ceases using them.”</p>
<p>After the apt parable, everybody was submerged in silent thought for a while. Then Romantic suggested, “Why don’t we pull over and talk about this all together with peace of mind? I’m really enjoying this.” But Rational did not share her perspective: “You know, I really would love to, but we have a long way to go. It is not wise to stop and forget about our trip. What are you going to do when we are all sleepy and not able to continue on the way? And what is wrong with talking while traveling, anyway?”</p>
<p>At the words of Rational, Romantic started crying: “You never listen to me; you always want me to forget my heart. I feel like I am among friends who are like dead statues.” Irritated by the words of Romantic, Regular took a turn, but talked in a way so as to manage the feelings of everybody: “Hey, umm… I think focusing on the discussion is a good idea, but it is not what we usually do. We are not near a lake or on top of a hill. It is neither sunset nor nighttime in a café. So, it may be better to wait until tomorrow.” Although these words were as neutral as they could be, Romantic still felt neglected: “I don’t think you are going to give yourselves to the matter if we keep going and talking at the same time. Instead, you are going to exploit and consume this lovely talk as a means to keep awake. This is a clear betrayal; it is hypocrisy toward your heart.”</p>
<p>“Wait a minute. I don’t think being wise is the same thing as hypocrisy. Do you have a really good reason to forget about everything else for the sake of this topic? I mean, what makes this topic so important that you want us all to sacrifice everything for it?” rebutted Rational.</p>
<p>Romantic could not answer this question, and turned her face outward into the darkness veiling the fresh green of the trees. She thought, “I am just like those trees and flowers that suffer from not being able to display their beauty because of the darkness.”</p>
<p>Reductionist, who was driving while listening to all the talk, said, “What is it that you are aiming to get from this talk, whether we do it now or later? I don’t want to be discouraging here, but isn’t this another hay-fire that is going to give a burst of heat and light, but will prove ordinary and transient in the end? This is just another emotion-provoking breeze about inspiration. I have experienced several of those, and yet here comes another. What difference is this going to make when we already have thousands of them out there? What is the point in discovering America over and over?”</p>
<p>Hearing all these arguments, Romantic, Rational and Regular all shut their mouths. Although the three roommates wanted to talk about the new perspective that Romantic had presented, their dispute about how to do it had weakened them in the face of Reductionist’s arguments. Nobody could say a word after Reductionist had spoken, and silence covered the quartet like the night.</p>
<p>Although she had been upset by the rest of the group, Romantic was still awake and happy in her mind. She decided to daydream about previous inspirations she had received. That way, she lived again the exhilaration and joy that came along with them. Triggered by that energy, Romantic gave a giggle that disrupted the increasing weight of the dark and silence. Rational, who was sorry to have upset Romantic, used this as an opportunity: “I have an idea. By going slower, we can sincerely concentrate on each other and on Romantic’s inspirations. That way, we can convert our trip into a journey toward the making of an article.” This suggestion triggered Regular to say: “Yeah, depressed nights, too, are part of our custom for in-depth talks.” Now everybody was waiting for Reductionist to approve the idea. Reductionist first slowed down. The reduction of the noise from the engine strengthened the silence. In the tense atmosphere, Reductionist laughed like a thunderclap, and said, “I am going to tell you guys a little story. A writer had three pens. He picked the first one and wrote an article with it. After finishing it, the pen said, ‘I wrote this article for you. Do you like it?’ The writer smiled back and said, ‘Yes, thank you.’ Then the writer put that pen in his office so that it could do things for him. Another day, the writer used the second pen to write a piece. After he finished it, the pen turned to him and said, ‘I wrote what you told me. Do you like it?’ The writer smiled back and said, ‘Yes, thank you.’ Then the writer put that pen in his bag so that it would write things as he wanted. And finally the writer used his third pen to write another article. After finishing it, the pen turned to him with a smile and said, ‘Thank you for using me.’ The writer smiled back at the third pen and put it in his pocket right next to his heart. He carried it everywhere he went, and whenever he had an original idea, he welcomed it with the help of his third pen.”</p>
<p>By that time, the rain outside had turned into a rain of smiles inside the car. Motivated by the unexpected story Reductionist had told, everybody engaged in an effort to welcome the inspiration that came through the one next to the heart. Romantic was not late taking her turn: “You know, for everything there is a season. You have to sow your seeds in the fall and wait until summer to reap. If you sow any time else, you not only waste your time but also lose your seeds. So, I guess the best time to work on an idea is when it first descends from the heavens to your heart.”</p>
<p>Both Regular and Rational looked at Romantic with wide open eyes. Regular said, “You have an important point there.”</p>
<p>“That is absolutely right,” concluded Rational.</p>
<p><em>Seth Mette has a PhD in Aerospace Engineering and is currently working as a postdoctoral fellow at West Virginia University. He has a special interest in psychological fiction.</em></p>
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		<item>
		<title>The Dancing Pen</title>
		<link>https://fountainmagazine.com/all-issues/2009/issue-68-march-april-2009/the-dancing-pen/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sun, 01 Mar 2009 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 68 (March - April 2009)]]></category>
		<category><![CDATA[art]]></category>
		<category><![CDATA[bamboo]]></category>
		<category><![CDATA[calligraphy]]></category>
		<category><![CDATA[centuries]]></category>
		<category><![CDATA[Culture & Society]]></category>
		<category><![CDATA[dance]]></category>
		<category><![CDATA[dancing]]></category>
		<category><![CDATA[era]]></category>
		<category><![CDATA[hat]]></category>
		<category><![CDATA[islamic]]></category>
		<category><![CDATA[music]]></category>
		<category><![CDATA[muslim]]></category>
		<category><![CDATA[osman]]></category>
		<category><![CDATA[ottoman]]></category>
		<category><![CDATA[pen]]></category>
		<category><![CDATA[produced]]></category>
		<category><![CDATA[sahin]]></category>
		<category><![CDATA[style]]></category>
		<category><![CDATA[time]]></category>
		<category><![CDATA[writing]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2009/issue-68-march-april-2009/the-dancing-pen/</guid>

					<description><![CDATA[No one knows dancing like him. Swirl, lift, dip. The routine continues. Swirl, lift, dip. This is what Osman Sahin does to relax. Dance. But he is no choreographer, he is a calligrapher-one who has mastered the art of Classical Turkish-Islamic calligraphy for over twenty-five years. He calls his calligraphy style “the dancing of the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>No one knows dancing like him. Swirl, lift, dip. The routine continues. Swirl, lift, dip.</p>
<p>This is what Osman Sahin does to relax. Dance. But he is no choreographer, he is a calligrapher-one who has mastered the art of Classical Turkish-Islamic calligraphy for over twenty-five years. He calls his calligraphy style “the dancing of the pen.”</p>
<p>His eyes, eagerly glued to the paper, anticipate his next move. His hands lift with each pen stroke, gliding to the rhythm of his breath, rising with every new thought and slowing to the pace of his heartbeat.</p>
<p>To many of us, calligraphy is merely fancy handwriting used to record information, but to a Turk calligraphy is much more. It is an art-a grand form of art-with its origins dating back many centuries. The Turks refer to calligraphy as Hat (pronounced like “hut”). In its literal sense, Hat means beautiful writing practiced and perfected throughout time as a way to combine spiritual and functional writing with the medium of art.</p>
<p>It is however the spiritual element of Hat that is most striking to viewers. Because the drawing of human figures is not favored in Islam, Muslim artists throughout time have channeled their talents toward the art of calligraphy.</p>
<p>“Hat is all about symmetry, harmony and measurements,” explains Osman Sahin. “It is the dance of the pen and paper. It’s music to the eyes. Hat is like composed music that soothes and refreshes the spirit and brings peace and harmony to the soul. It enables the person to reach inner tranquility.”</p>
<p>The origins of Hat date back to the early Islamic era when manuscripts of the Qur’an were being recorded and handwritten. However, at that time there was little emphasis on the style of writing but greater emphasis on the message being revealed. It was centuries later, during the Ottoman Era, that Turks focused on the style of writing.</p>
<p>It is a common saying among Muslims that “the Qur’an was revealed in Mecca, recited in Egypt and written in Istanbul.” The Ottoman Turks produced and perfected various styles of script that were passed on throughout the Muslim world.</p>
<p>They loved and respected the art of Hat as it flourished in the great city of Istanbul, which was at the time the focal point of the Ottoman State, and it was there that history’s finest works were produced.</p>
<p>Hat has been used throughout Turkey in enchanting ways to decorate palaces, mosques, museums and fountains for many centuries. The renowned Spanish artist Pablo Picasso, referring to the art produced by Muslim calligraphers during the Andalusian period, said, “Muslim calligraphers five hundred years ago reached where I want to reach today.” In present-day Turkey, there are over twenty million artwork treasures that bear witness to this history.</p>
<p>The beauty present in Islamic-Turkish calligraphy is said to be a direct reflection of the inner soul of the calligrapher. As Osman Sahin himself says, “Whenever I am stressed, I pick up my pen and draw. This is because the art of Hat has a therapeutic aspect to it. During the Ottoman era, some of the sick were treated by using fine arts like Hat together with soothing Sufi music and the art of Ebru (water marbling) drawing.”</p>
<p>This extraordinary art form can only be executed with the use of pens made of bamboo cuttings, preferably Balinese bamboo. “The bamboo is cut at a thirty-degree angle and split in half from top to bottom,” demonstrates Osman Sahin. “Even with the technology present today, it is not possible to write better or more beautifully using anything other than bamboo. The squeaking sound you hear when using the bamboo pen is said to be the weeping of the pen. It is said that the pen weeps so as to not fall into the hands of the ignorant.”</p>
<p>It is no surprise that there is wonder and magic in Turkish-Islamic calligraphy. It is almost as if the art moves and comes alive. Sweet appearance follows a slow, inner flow. There is silence, yet harmonious and metaphysical music echoes. However, this music cannot be heard by the ears but must be heard within.</p>
<p>He breathed in and leaned back comfortably in his chair, looking deep into his finished calligraphy as it stared back at him. The dance was over, the rhythm ceased, and the music was muffled. The bamboo pen lay there on the table, weeping with heartache, unaware of when the next dance will be.</p>
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