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		<title>Breathe In, Breathe Out, Carry On</title>
		<link>https://fountainmagazine.com/all-issues/2019/issue-130-july-aug-2019/breathe-in-breathe-out-carry-on/</link>
		
		<dc:creator><![CDATA[The Fountain]]></dc:creator>
		<pubDate>Mon, 01 Jul 2019 23:26:55 +0000</pubDate>
				<category><![CDATA[Issue 130 (July - Aug 2019)]]></category>
		<category><![CDATA[A Moment for Reflection]]></category>
		<category><![CDATA[Arts and Culture]]></category>
		<category><![CDATA[asked]]></category>
		<category><![CDATA[began]]></category>
		<category><![CDATA[eyes]]></category>
		<category><![CDATA[feel]]></category>
		<category><![CDATA[floor]]></category>
		<category><![CDATA[hands]]></category>
		<category><![CDATA[house]]></category>
		<category><![CDATA[left]]></category>
		<category><![CDATA[life]]></category>
		<category><![CDATA[mind]]></category>
		<category><![CDATA[mom]]></category>
		<category><![CDATA[mom’s]]></category>
		<category><![CDATA[pills]]></category>
		<category><![CDATA[talking]]></category>
		<category><![CDATA[tears]]></category>
		<category><![CDATA[time]]></category>
		<category><![CDATA[told]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2019/issue-130-july-aug-2019/breathe-in-breathe-out-carry-on/</guid>

					<description><![CDATA[It was a blustery February morning, and just a few days before my 40th birthday, when my cell phone rang. I thought perhaps it was someone offering me early well wishes. But it was my mom, calling with news that would forever alter the course of my life. “Hi, Mom,” I said as I sat [&#8230;]]]></description>
										<content:encoded><![CDATA[<p><img fetchpriority="high" decoding="async" class=" size-full wp-image-6728" src="https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958.jpg" alt="Breathe In, Breathe Out, Carry On" width="1920" height="1200" srcset="https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958.jpg 1920w, https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958-300x188.jpg 300w, https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958-1024x640.jpg 1024w, https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958-768x480.jpg 768w, https://fountainmagazine.com/wp-content/uploads/2019/07/10_breathe_in-958-1536x960.jpg 1536w" sizes="(max-width: 1920px) 100vw, 1920px" /></p>
<p>It was a blustery February morning, and just a few days before my 40<sup>th</sup> birthday, when my cell phone rang. I thought perhaps it was someone offering me early well wishes. But it was my mom, calling with news that would forever alter the course of my life. </p>
<p>“Hi, Mom,” I said as I sat down. “How are you?”<br /> “Not good,” she whispered like a frightened child sharing a dark secret. “You know I’ve been feeling really down lately.” </p>
<p>“Yeah,” I said softly, matching her breathy tone. </p>
<p>She was talking so quietly that I cupped my hand over my left ear so I could hear her.<br /> “I just swallowed a bunch of sleeping pills,” she blurted out.</p>
<p>My eyes widened as I sprung to my feet, nearly tripping over my toddler.</p>
<p>“A bunch? Like, how many?” I asked.</p>
<p>“I dunno,” she replied. “A lot.”</p>
<p>I raced to the kitchen, my hands trembling as I fumbled to dial 911 from the landline while trying to keep Mom talking to me on my cell.</p>
<p>A few moments later, I told her that the paramedics were on their way. She mumbled something incoherent. I could already feel her drifting away.</p>
<p>“Can you hear me?”</p>
<p>Numbing silence filled the line. Desperate to keep her awake, I continued talking, my voice growing louder each time I spoke.</p>
<p>“Are you still with me? <em>Mom? Mom!</em>”</p>
<p>Sensing the intensity to my tone, my 8-year-old son asked what was wrong. I wanted to comfort him, but I had to keep focused on Mom. Meanwhile, my toddler, who had only just realized his grandmother was on the phone, threw his goldfish crackers to the floor and pleaded to speak with her. He reached for the receiver with his tiny, cheddar-stained hands and shrieked, “I talk to Ga-ma!”</p>
<p>“Not now,” I said gently.</p>
<p>Both my boys burst into tears as my mind raced with worry. I paced the floor and repeatedly asked, “Are you still there, Mom? Keep talking to me.”</p>
<p>But I only heard a hint of monosyllabic mumbles, then a thud.</p>
<p>I stopped for a moment and stood beside the sliding glass door, shifting my weight from my right leg to my left as I stared out at the falling snow. I kept my eyes fixed on a specific tree branch in an effort to still my mind even as my restless stomach churned.</p>
<p>The wind whipped wildly, which made the snowflakes look as if they were engaged in a vicious game of tug-of-war. Blowing in umpteen different directions, the blustery scene depicted my current state of mind: frenzied, scattered, unsettled. My anxious eyes darted back and forth between the ticking clock, my wailing kids, and the straining pine trees in the backyard.</p>
<p>Finally, I heard the paramedics in the background and for the first time in forever, I took a breath.</p>
<p>I shot off a text message to my brother.</p>
<p>“Call me,” I wrote. “Mom just tried to kill herself.”</p>
<p>Even as I hit “send” with my quivering thumb, the moment seemed surreal. Did this really just happen? How? Why?</p>
<p>As I drove to Missouri, I tried to imagine what was running through my mom’s desperate mind as she ingested an entire bottle of sleeping pills. I envisioned her in her soft flannel pajamas, sitting on the cold tile bathroom floor, swallowing one handful of pills after another. My eyes squeezed shut and a lump formed in the back of my throat. I knew clinical depression was scary, but I’d never seen it up-close-and-personal.</p>
<p>When I stepped inside the hospital room, Mom’s eyes revealed a mixture of sorrow, regret, guilt, and fear. I sat next to her on her bed. She clasped my hand in hers, gripping it tightly.</p>
<p>“I’m sorry,” Mom said softly, staring at the floor. </p>
<p>It’s okay,” I replied.</p>
<p>The truth was that it <em>wasn’t</em> okay. Not even a little bit. But what else could I say?</p>
<p>I stayed with her for several days, trying to soothe her by offering hugs and encouraging her by offering advice.</p>
<p>“Go to group therapy. Go to individual therapy. Do anything and everything to help you feel better,” I suggested. “Snarf up every resource possible.”</p>
<p>But instead of concentrating on getting better, she seemed more concerned with how her behavior would be perceived.</p>
<p>“What will people say if they find out what I did?” Mom asked, her eyes brimming with tears.</p>
<p>After she was released from the hospital, I went back home to Indiana. The following month, I was cautiously optimistic when Mom invited me, my husband, and our sons to visit her for her birthday and stay through Easter weekend. I took it as a good sign that she wanted to reconnect with her grandsons, so we packed our bags and drove west.</p>
<p>Though it was great to spend time with Mom, she was anxious and unsettled, worried that the kids might make a mess in her house. This was a far cry from the woman who in the past would often jump into the lake to entertain her grandsons. She spoke slowly and methodically yet still stumbled on her words. She seemed uncomfortable in her own skin. She wouldn’t even sit down to eat meals. Instead she stood by the sink, nervously nibbling at her food like a rodent.</p>
<p>One morning when the house was quiet, Mom approached me and said meekly, “Christy. I have to tell you something.”</p>
<p>“What is it?”</p>
<p>I didn’t want to rush her or force her, but I was desperate to hear what she had to say.</p>
<p>“I haven’t been completely honest with you,” she said, squeezing my hands as if to relay some sort of message to me through code.</p>
<p>“Honest about what?”</p>
<p>She opened her mouth, but no words came out. I pressed her a bit more.</p>
<p>“You can tell me, Mom. Whatever it is, I’ll help you. What are you not being honest about?”</p>
<p>“We’d better get ready,” she said tersely, releasing my hands. “The boys want to go to the zoo today.”</p>
<p>Just like that, the moment was gone.</p>
<p>At the zoo, the kids had fun seeing the animals and riding the train, but I couldn’t get past the vacant stare in Mom’s eyes. It was like she was looking past everybody—like she wasn’t all there. Anytime I tried to engage with her, I’d get the same response: “I’m tired.”</p>
<p>That evening after tucking the boys into bed, I asked Mom if she wanted to talk. She looked at me with a pained expression, like she was gripping a hot plate without a pot holder.</p>
<p>“Well, I…um, I,” she muttered.</p>
<p>I don’t know if she couldn’t speak or wouldn’t speak or what was going on. But her mind definitely seemed muddled. I knew something was gnawing at Mom, but I didn’t know how to pull it out of her.</p>
<p>When I laid down to bed that night, tears welled up in my eyes as I confided to my husband, “I think Mom may still be suicidal.”</p>
<p>I hated to admit it out loud, and yet, I could sense a definite heaviness to her spirit.</p>
<p>“Why do you say that?” Eric asked.</p>
<p>“I can’t put my finger on it, but she’s definitely not herself. She’s apologized profusely for trying to kill herself, but earlier today she told me that she’s not been completely honest with me, and when I asked her what about, she clammed up. Have you noticed how empty her eyes look?”</p>
<p>“What do we do? Your dad won’t listen. He’s adamant that she’s getting better.”</p>
<p>“But clearly she’s not. I wish I could get her to confide in me, but I feel like us being here is stressing her out more,” I said. “If the boys’ energy is causing her anxiety to spike, maybe we should take off and let her and Dad have a quiet holiday weekend.”</p>
<p>“Okay,” Eric agreed.</p>
<p>The next morning, I found Mom in the kitchen. She wasn’t eating, cooking, or doing dishes. She was simply standing in her housecoat staring into space. Until she caught a glimpse of my oldest son. Then her eyes moved to him and she watched him intently, like she was memorizing his every move. She did the same when my younger son entered the room. When I sat down, she acknowledged me with a weak, forced smile like she was using every last bit of energy to keep from crying.</p>
<p>I approached her and said softly, “Mom, we’ve decided to leave early.”</p>
<p>“When?”</p>
<p>“Here in a few minutes,” I said. “Eric’s packing the car.”</p>
<p>Confusion, sadness, and relief simultaneously spread across her face.</p>
<p>“Why today?” she asked.</p>
<p>“I can tell you’re struggling, Mom, and I know the boys have a lot of energy. I want you to be able to rest so I think it’s best if we get out of your hair.”</p>
<p>Her lips began to quiver, her brows furrowed, and she said with palpable remorse, “I’m sorry, Christy. I’m <em>so</em> sorry.”</p>
<p>It was a phrase she had repeated numerous times over the past three days so I didn’t think much of it. I replied in the same way I had all weekend—by telling her, “It’s okay.”</p>
<p>We hugged and I told her I loved her.</p>
<p>“Things will get better,” I whispered into her ear. “I promise.”</p>
<p>Those were the last words I ever spoke to my mother.</p>
<p>Six weeks later, my phone rang again. When I answered, I heard my dad’s voice, low and scratchy, say my name, followed by a long pause. </p>
<p>“She did it again,” he said quietly.</p>
<p> My gut clenched as all the color drained from my face. </p>
<p> “What?” I asked.</p>
<p> “She was doing better. She seemed stronger….” he said, his voice cracking.</p>
<p>My entire body began to tremble.</p>
<p>“It’s far worse this time,” he continued. “She swallowed hundreds of pills of all different kinds.”<br /> My knees buckled.</p>
<p>“No-no-no-no,” I repeated.</p>
<p> How could this be happening again?</p>
<p>“I’ll jump in the car,” I told my dad as tears sprang to my burning eyes. “I can leave right now and be there by midnight.”</p>
<p>“Even if you left now, I don’t think you’d make it in time to say goodbye.” </p>
<p><em>Wait. What? Goodbye? Oh, Jesus!</em> </p>
<p>My breath caught in my throat as my heart splintered. </p>
<p>When I got news in the middle of the night that Mom had died from the overdose, my world faded to grey. </p>
<p><em>Why? Why? Why? Why?</em> </p>
<p>A thousand other questions bombarded my brain, but this was the predominant one. I could not, for the life of me, make sense of the fact that my sweet, loving, kind, compassionate mom would choose to take her own life. It defied logic and left me feeling helpless, hopeless, and hollow. How was I supposed to go on? How was I to let go of the guilt that gnawed at me round the clock? How was I to ever smile again? None of it seemed possible. </p>
<p>“Everything’s possible with God,” well-meaning people told me. But their platitudes and looks of pity only pissed me off. They didn’t know what it felt like to be leveled by grief. Though friends encouraged me to find peace through prayer, I did the opposite and gave God the silent treatment. What did I have to say to Him, anyway? I was angry that He had not only taken away my mom but that He had allowed her to exit the earth in such a terrible, tragic way. Having been a Christian all my life, I’ll admit it felt strange to cut Christ from my life, but I didn’t know what else to do. Many days, I found myself curled in the fetal position, sobbing and gasping for air. </p>
<p>Over the next six months, everything was a chore—driving, cooking, reading, even sleeping. Then one night I fell into a deep slumber and was met by a vivid dream that seemed to carry with it a distinct message.<br /> I was at home when suddenly bright blue skies began to darken as a slight breeze tickled the shutters. Instantaneously, the sky transformed into a greenish-black hue. A small hiss followed a rumble, then a booming crash. The ground shook with a sinister force. Giant tree limbs snapped. Heavy shutters broke. Tin mailboxes crumpled. Wooden dog houses cracked. As the wind continued to howl, dirt, debris, and trash swirled through the air like frenzied snowflakes. Fence sections and lawn ornaments crashed through windows and dented car doors.</p>
<p>The scene was chaotic and scary. I glanced out the window, helpless and weak. Then, just as quickly as it built, the storm died out, and the world grew eerily still. I stepped outside to assess the damage and my jaw dropped at the sight of the devastation. Our beautiful house—a house I had always perceived to be strong and indestructible—was now a shell of its former self.</p>
<p>As I walked the perimeter of the house, I saw that it was uprooted from its foundation. It became evident that we wouldn’t have access to power or water anytime soon. It was going to take a lot of time and effort to rebuild this foundation—to start fresh. As a result, we would not be living comfortably for quite some time.</p>
<p>There was a silver lining, however. Despite such extensive damage, we determined that we could stay in the house, which provided a degree of comfort.</p>
<p>I stood in stunned silence, beholding the wreckage that surrounded me. I couldn’t believe the massive devastation that had leveled my life in the blink of an eye. But…I had survived.</p>
<p>For the first time since Mom’s suicide, I woke up with a sense of peace. I knew I would still face challenges and cry countless tears. But I had survived the worst, and though my foundation was shaky, I was still standing. And I could feel God standing beside me.</p>
<p>In the weeks and months ahead, I began surrounding myself with others who needed love and support, and, together, we journeyed through our pain: we shared tears, smiles, and embraces, and we held one another up, day in and day out. I learned that being in a community is perhaps the most important piece of life’s puzzle when it comes to maintaining a healthy existence. I also found that even in the deepest, darkest pit of despair, one can find a sliver of light, a glimmer of hope, a hint of peace. And that is what propels us forward, enabling us to breathe in, breathe out, and carry on.</p>
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		<title>Stem cells as an arthritis vaccine</title>
		<link>https://fountainmagazine.com/all-issues/2017/issue-117-may-june-2017/stem-cells-as-an-arthritis-vaccine/</link>
		
		<dc:creator><![CDATA[The Fountain]]></dc:creator>
		<pubDate>Mon, 01 May 2017 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 117 (May - June 2017)]]></category>
		<category><![CDATA[arthritis vaccine]]></category>
		<category><![CDATA[Caterpillar]]></category>
		<category><![CDATA[pills]]></category>
		<category><![CDATA[Science Square]]></category>
		<category><![CDATA[Stem Cells]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2017/issue-117-may-june-2017/stem-cells-as-an-arthritis-vaccine/</guid>

					<description><![CDATA[Stem cells as an arthritis vaccine Brunger JM et al. Genome Engineering of Stem Cells for Autonomously Regulated, Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports, April 2017. Arthritis is an ancient disease that is associated with swelling and inflammation of the joints. It often results in stiffness, pain, and restriction of movement. In most [&#8230;]]]></description>
										<content:encoded><![CDATA[<h3>Stem cells as an arthritis vaccine</h3>
<p><em>Brunger JM et al. Genome Engineering of Stem Cells for Autonomously Regulated, </em><em>Closed-Loop Delivery of Biologic Drugs. Stem Cell Reports, April 2017.</em></p>
<p>Arthritis is an ancient disease that is associated with swelling and inflammation of the joints. It often results in stiffness, pain, and restriction of movement. In most cases of arthritis, the range of necessary treatments is very limited and common pharmaceutical treatments simply relieve the symptoms. However, a new study using stem cell technology may lead to the development of an arthritis vaccine that specifically targets inflammation in joints and stops pain before it even starts. Researchers used CRISPR technology, a revolutionary gene-editing tool, to reprogram mouse stem cells to combat inflammation caused by arthritis. These newly generated stem cells are called SMART (<u>S</u>tem cells <u>M</u>odified for <u>A</u>utonomous <u>R</u>egenerative <u>T</u>herapy). They are designed to develop into cartilage cells that produce anti-inflammatory agents. They also end up replacing damaged cartilage, reducing chronic arthritis-related inflammation. Researchers hope to package these reprogrammed stem cells as a vaccine for arthritis, which would deliver an anti-inflammatory drug to an arthritic joint, but only when needed. Current arthritis medications are given systemically, meaning they have the potential to interfere with other parts of the body. Since SMART cells deliver the medication only to the targeted location, this will significantly reduce the systemic effects.  The question is: will they be effective? In trials, SMART cells were observed to grow into cartilage tissue and even protect against inflammation over the course of a few days in mice.  Further testing is still in its initial phase in mouse models.  These stem cells have been engineered to fight rheumatoid arthritis.</p>
<p><span id="more-5245"></span></p>
<h3>Plastic-eating caterpillars</h3>
<p><em>Bombelli P. et al. Polyethylene bio-degradation by caterpillars of the wax moth Galleria mellonella, Current Biology, April 2017. </em></p>
<p>Plastics are made of synthetic materials consisting of polymers, long strings of molecules derived from fossil fuels. Since they have a half-life of approximately 450 years, every piece of plastic that has ever been made is with us today, except for the very small amount that we&#8217;ve burned. Polyethylene, from which plastic bags are manufactured, is one of the plastic types that is the most resistant to degradation. Since stores give out more than one trillion polyethylene plastic bags every year, these indestructible plastics are accumulating all over the globe and pose serious environmental problems.  Scientists have long been searching for effective and environment-friendly solutions to eliminating plastic trash. One approach is to exploit simpler organisms, as they can be adept at utilizing unusual energy sources. After a lot of trial and error, researchers found that larva of a common insect, <em>Galleria mellonella</em>, is able to biodegrade polyethylene. <em>Galleria mellonella</em>, whose larvae are also known as waxworms, was discovered to do a significant amount of damage to a plastic bag in less than an hour. The follow-up tests detected the presence of the basic building block of polyethylene, ethylene glycol, in the waxworms&#8217; guts, demonstrating that the waxworms were indeed digesting polyethylene; they were not merely chewing it up into smaller pieces that passed through their guts unaltered. These results were initially puzzling to scientists; they couldn’t understand how waxworms were able to digest a substance that had only begun to be manufactured in the last century. The answer came from the ecology of the waxworm itself. Waxworms are a well-known pest to beekeepers, as they grow and feed on wax and honey. Since wax is a polymer with a very similar chemical structure to polyethylene, waxworms seem to already know how to digest polymer structures like plastics. Scientists still don’t know whether the polyethylene digestion is done by the waxworm itself or if it is relying upon the bacterial flora within its gut. As they learn more about the digestion mechanisms, they hope to design practical and effective biotechnological solutions for managing plastic waste, which will ultimately protect our oceans, rivers, and overall environment.</p>
<h3>Pill for exercise?</h3>
<p><em>Weiwei F et al. PPARδ Promotes Running Endurance by Preserving Glucose. Cell Metabolism, May 2017.</em></p>
<p>The benefits of exercise are well-known. Unfortunately, there are people who are obese, elderly, or mobility-limited and cannot benefit from exercise. To offer them a solution, scientists discovered a drug called GW1516 which mimics the beneficial effects of exercise, including an increased stamina and a higher rate of fat burning. While the control mice could only run 160 minutes on a treadmill, mice with the experimental drug lasted 270 minutes—about 70 percent longer. The discovery of GW1516 came from scientists’ previous knowledge of genetics. Scientists already knew that genetically activating the gene called PPAR delta enabled mice to run a lot longer than normal without getting tired.  Moreover, these mice are much less likely to gain weight or become diabetic. Scientists basically designed a chemical compound that activates the PPAR delta. The research team also analyzed the wide range of physiological effects of GW1516.  While the genes that break down fat for energy did more work in the mice with GW1516, genes that break down carbs for energy did less work. This is somewhat expected, as the bodies of really fit people typically burn fat, not carbs, for fuel. Despite these differences, GW1516 didn’t improve muscle mass. The only benefit seems to come from changing how the body breaks down energy. Although the initial studies have been done in mice, scientists are eager to develop clinical trials for humans as soon as possible.</p>
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		<title>Vitamin and Mineral Pills: The Right Answer for a Healthy Life?</title>
		<link>https://fountainmagazine.com/all-issues/2008/issue-63-may-june-2008/vitamin-and-mineral-pills-the-right-answer-for-a-healthy-life/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Thu, 01 May 2008 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 63 (May - June 2008)]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[effects]]></category>
		<category><![CDATA[food]]></category>
		<category><![CDATA[health]]></category>
		<category><![CDATA[Health & Medicine]]></category>
		<category><![CDATA[june]]></category>
		<category><![CDATA[life]]></category>
		<category><![CDATA[media]]></category>
		<category><![CDATA[minerals]]></category>
		<category><![CDATA[multivitamin]]></category>
		<category><![CDATA[people]]></category>
		<category><![CDATA[pill]]></category>
		<category><![CDATA[pills]]></category>
		<category><![CDATA[supplements]]></category>
		<category><![CDATA[synthetic]]></category>
		<category><![CDATA[vitamin]]></category>
		<category><![CDATA[vitamins]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2008/issue-63-may-june-2008/vitamin-and-mineral-pills-the-right-answer-for-a-healthy-life/</guid>

					<description><![CDATA[In human health, the importance of vitamins is indisputable. Proof of this are the numerous illnesses associated with a lack of vitamins in the diet. Motivated by such established facts, consumers want to make sure that they are consuming the right amount of vitamins in their daily food. However, the processing methods used in the [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>In human health, the importance of vitamins is indisputable. Proof of this are the numerous illnesses associated with a lack of vitamins in the diet. Motivated by such established facts, consumers want to make sure that they are consuming the right amount of vitamins in their daily food. However, the processing methods used in the food industry degrade the nutritious quality of products. As a result, people feel there is a need for direct vitamin intake to compensate for the vitamin deficiency in processed food. There are several unanswered questions in this practice which demand urgent action to protect public health.</p>
<p><span id="more-904"></span></p>
<h3><b>Vitamin basics</b></h3>
<p>Vitamins and minerals are key nutrients that are essential in the regular functioning of the human body. They are needed in small amounts and are usually acquired from vegetables and fruits (Dobson 12). When acquired properly, vitamins can competently play the role assigned to them and they can observe their duties, such as to keep the immune system running, contribute to the structural integrity of the body, and strengthen the sensory systems. Their deficiency in the body leads to problems in these systems, which may result in lethal risks for health. For example, “lack of vitamin D damages immunity to cause cancers, diabetes and infections” (Mirkin).</p>
<p>Vitamins can be classified as water soluble and fat soluble. Generally, the vitamins that are soluble in water are absorbed by the body in the quantities that are needed. The excess is excreted in urine. Thus, it appears that abundant use of pills containing such vitamins produces nothing but expensive urine. As for the vitamins that are soluble in fat, their excess is stored in fat tissues and is retrieved in case of need (“Vitamins and Minerals”). This is an undesired effect, because it tires the body, which is otherwise a perfectly adjusted system.</p>
<h3><b>Motivation for vitamin supplements</b></h3>
<p>In the last century, a lot of research has been done to establish the amounts of vitamins and minerals needed for regular functioning of the body. With this knowledge, there is a growing concern among the public about their nutrition in recent years. People often think that the foods they are consuming do not contain necessary or sufficient amounts of vitamins and minerals.</p>
<p>It is not difficult to see that this concern has been formed by the artificial agendas of certain specialists. These specialists use methods that evoke feelings of anxiety, fear, desire, and the wish for perfection. The visual media and the press have certainly been the main and most effective means of propagating this agenda. Based on consultation with the specialists, vitamin-producing companies make promises to the consumers through advertisements that highlight how good vitamins are for children, adolescents and the elderly. They promise, for example, that if certain vitamins are used, people will feel better, improve their memory or remove aging effects. They claim that some of the vitamins they are selling have a healing or preventive power against diseases about which people are most concerned or fearful. Cancer, cardiovascular problems and obesity are among the most commonly emphasized such diseases. In the same way, abusing people’s desire for a long life, they claim that some vitamins increase life expectancy. For children, their inherent desire to be like adults is abused and they are promised that if they use certain vitamins they will be strong. These claims are reinforced with video clips in order to make them appear more realistic, and they are further supported by frequent repetition in the visual media.</p>
<p>Food supplements designed to meet the needs of the body are also put in “costumes” to allure the consumers. Product packaging uses big bullet points to present information about their extra vitamin content. In parallel to this, in the stores where these vitamins are sold, life-size pictures of famous or well-built people are displayed.</p>
<h3><b>The Vitamin Market</b></h3>
<p>As a result of all these efforts, many people think that a healthy life is not possible without vitamin pills. According to a survey by the USDA (United States Department of Agriculture) two decades ago, around fifty percent of the population from 19–50 takes a multivitamin pill every day. That survey showed a significant increase compared to another one performed five years earlier (Driskell). According to this trend, the vitamin supplement consumption is likely to have achieved much higher levels in our time.</p>
<p>Thus, an enormous market has formed for vitamin and mineral pills. It is estimated that this market amounts to an annual sales value between three and five billion dollars (Anderson, Wilken). With a drive to get a share of the sales, all supermarket chains have opened sections for vitamin pills and sell various kinds of vitamin supplements. Not only is the vitamin industry doing all these promotions for its own benefit, but media companies are also thriving on such advertisements. Unfortunately, this is sometimes a major reason for the media not to go after certain issues.</p>
<h3><b>What is wrong? </b></h3>
<p>Research shows that people get the correct quantity of vitamins and minerals if they consume a variety of natural foods and drinks. In countries with a high per capita income, some foods and drinks are even enriched with extra vitamins to ensure that vitamins are taken in sufficient amounts. As a result, for a person who is on a normal diet, a multivitamin pill is very likely to be excessive. With regard to these pills, nobody knows what amount is good for which person under what conditions. It is strange that the quantity of fruits and vegetables corresponding to the same amount of vitamin contained in a multivitamin pill is not revealed. Perhaps if this were calculated, the insanity of vitamin supplements would become evident. Do we really need to eat as many vegetables as a cow or a horse?</p>
<p>At the top of the direct vitamin intake options are vitamin pills. The majority of vitamin pills are marketed as a multivitamin-combinations of different vitamins and minerals. Supplying various combinations of vitamins in a single pill seems like a good idea at first. However, when we look at the production of vitamin pills, we see that the production process has not been standardized. Each company makes its own vitamin combinations and markets them. On top of their content, the daily consumption of synthetic vitamin pills is also variable based on the demands of the individual consumer. Although some companies include a recommendation on the packaging, in the end they say that their product can be consumed to the extent it is needed. For many vitamin pills, information about their solubility in water or fat is not present either. However, such pieces of information are of vital importance for their healthy consumption.</p>
<p>In recent times, with their wider use, these synthetic pills have been held responsible for health problems, contradicting expectations of health improvement, but so far they have not gained a bad reputation related to side-effect or harm. The prevailing view is that the more vitamins one takes, the better one’s health. This view might be true for natural vitamins; however, it is not so for synthetic vitamins. Generally, side-effects are associated with high dosages and undiluted intake, neither of which occurs in their natural counterparts.</p>
<p>Multivitamin pills are usually combined with minerals. Thus, while taking vitamin supplements, minerals are also taken, regardless of the need for them. However, similar to vitamins, minerals also are bad for human health when taken in excess. They interact with and counteract each other, and hence they disturb the body’s equilibrium.</p>
<p>In a study by Goran Bjelakovic and Christian Gluud, which was published in the journal of National Cancer Institute, it is stated that “Our diets typically contain safe levels of vitamins, but high-level antioxidant supplements could potentially upset an important physiological balance” (Bjelakovic, Gluud 742). They claim that antioxidant vitamins (A, C, E) do not provide any benefit when consumed in pills: if they are used as such, each results in certain forms of harm according to their function in the body. Bjelakovic and Gluud proved that such vitamin pills neither prevent nor cure cancer, that they do not protect the cardiovascular system, do not increase life expectancy nor alleviate the effects of aging. On the contrary, they showed that these antioxidant vitamin pills increase the risk of the diseases mentioned above. For example, a male person who is taking one multivitamin pill per day is doubling his risk for developing prostate cancer.</p>
<p>Some supplements can also have drug-like effects which present risks for people with certain medical conditions. A vitamin supplement brand was found to have potentially dangerous interactions with a number of prescription drugs (“‘Miracle’ Health Claims”).</p>
<p>At the very least, such side-effect-related cases call for a sound understanding of how these substances interact with the body. Can the human body convert synthetic vitamins to a usable form? Can they be stored and used later in case of vitamin deficiency? Are vitamin supplements, especially synthetic pills, as effective as natural vitamin sources, such as fruits and vegetables? What are the side effects associated with synthetic vitamins? What happens to vitamins in the case of overdose? Unless there are factual answers to these questions, vitamin pills should not be considered safe to use, and people should not use vitamin and mineral pills without consulting a doctor (“Vitamins and Minerals”).</p>
<h3><b>Watch out for your health! </b></h3>
<p>Here is the dilemma now: on the one hand, vitamin manufacturers are struggling to show the benefits of vitamin pills so that they make more profit; on the other hand, there is other research proving the detrimental effects of vitamin pills. At this point, it is nice to see a parallel dilemma in the fast-food market. If you go to a fast-food restaurant, their “nutrition facts” sheets show how healthy their food is. They even compare their food with other companies’ food in order to highlight their quality. However, there is a general consensus about unhealthiness of fast-food as demonstrated in the movie “Supersize Me”. Be it the food industry or the dietary supplement industry, there are claims from the producers which contradict the facts observed in real life. What to believe and who to trust are not clear.</p>
<p>One recourse in this ambivalence is the federal regulations or official advice from government scientists. In theory, health-care standards are established by either legislators or health organizations. However, in practice, there is a lack of institutes which can undertake the control of production of synthetic vitamin pills. In the US, for example, according to the Federal Trade Commission’s report, “Dietary supplements are not required to undergo government testing or review before they are marketed” (“Miracle’ Health Claims”). So, existing US health organizations, such as the FDA (Food and Drug Administration), do not accept any responsibility.</p>
<p>The main reason for not checking the harm associated with vitamin pills is that their side effects emerge in the long run. Consumers do not have the means to prove their cases, and consumer associations do not have enough financial power to take legal action against the producer companies. Therefore, there is no legal or practical base to pursue allegations related to the use of vitamin supplements. Given all this, using vitamin and mineral supplements is not very different from gambling with our health.</p>
<p>The above discussion provides enough information to evoke questions in the mind of the reader. Protecting people from the harm caused by vitamin pills is not possible through financial or judicial means at present, but it may be possible in the future through their long term results appearing as people with severe health problems. Let us hope that the people who have control over these issues will act in consideration of everybody’s health as an invaluable trust granted to them.</p>
<p><em>Alper Bursali is a senior student at West Virginia University, Biology Department. </em></p>
<h3><b>References</b></h3>
<ul>
<li>Bjelakovic, Goran, and Christian Gluud. “Surviving Antioxidant Supplements.” Editorial. Journal of the National Cancer Institute, 16 May 2007:742-743.</li>
<li>Dobson, Roger. “The A to Z of vitamins;” Independent Extra, 6 Mar. 2007. 25 June. 2007 http://web.lexis-nexis.com.www.libproxy.wvu.edu/universe/printdoc</li>
<li>Driskell, Judy A. Vitamin-Mineral Supplements and Their Usage by Adults. 28 June 2007 http://www.healthgoods.com/Education/Nutrition_Information/</li>
<li>Nutritional_Supplements/supplements_usage_adults.htm</li>
<li>Familydoctor.org 2004. Vitamins and Minerals: What You Should Know. Sept. 2004 http://familydoctor.org/online/famdocen/</li>
<li>home/otc-center/otc-medicines/863.html</li>
<li>Fogle, C., J. Anderson and K. Wilken. Mar. 2002. 29 June 2007 http://www.ext.colostate.edu/PUBS/foodnut/09338.pdf.</li>
<li>‘Miracle’ Health Claims: Add a Dose of Skepticism. September 2001. Federal Trade Commission. 20 June 2007 http://www.ftc.gov/bcp/conline/pubs/health/frdheal.shtm</li>
<li>Mirkin, Gabe. Lack of Vitamin D causes Cancer. 5 Mar. 2007. 27 June 2007 http://www.drmirkin.com/nutrition/1337.html</li>
<li>Sardi, Bill. Government/Scientific/Pharmaceutical/News Media Grip Over Dietary Supplements. 23 Jan. 2006. 27 June 2007 http://www.policestateplanning.com/dietary_supplements.htm</li>
</ul>
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