Original Article: Ramirez G. et al., Science 331, 211 (2011).

We have had to deal with tests and exams in academic and professional life from childhood on. Though we are motivated to perform our best, the pressure-filled situations generally cause us to perform below our abilities. University of Chicago researchers were interested in finding an intervention that would improve performance under such conditions, especially for those students who do not do well on exams because they are blocked by anxiety. Their study showed that simply writing down our thoughts and concerns immediately before a high-stress event can increase performance from 5–12 percent when it matters most. The simple brain-focusing exercise of writing down feelings for ten minutes before an exam reduces anxiety and increases exam scores significantly. The researchers concluded that writing allows individuals to reexamine the situation and revaluate concerns, reducing anxiety and increasing one’s ability to focus. This type of writing may help people perform their best not only on tests but also in variety of high-stress situations—a big presentation to a client, a speech to an audience, or even a job interview.

2- Life Without Starlight

Original Article: Hooper, D. & Steffen, J.H. (arXiv:1103.5086v1).

Liquid water is considered the common solvent to catalyze carbon-based life on planets. This assumption defines a rather tight region around stars, which is called the “habitable zone.” The energy absorbed from the host star through its light allows planets in the habitable zones to melt water into liquid. Water would either evaporate or remain ice if the planet is too close to or distant from the star. A recent study suggested that starlight may not be the only energy source that can convert ice into liquid water and maintain it in that state. Dark matter annihilation may produce enough heat in special circumstances for planets that may not be sufficiently heated by their host star. Ordinary matter constitutes only about 20 percent of the matter in the universe, while dark matter makes up about 80 percent of all matter. It is believed that dark matter weakly interacts with atomic nuclei. Therefore, one of the leading models for dark matter is called “weakly interacting massive particles” (WIMPs). In cases where dark matter interacts with nuclei, WIMPs can transfer momentum to the nucleus. Then they can get gravitationally captured and subsequently decay as energetic particles. This process can produce heat as a consequence. On Earth, the concentration of dark matter at its center is not sufficient to produce observable contributions to the planet’s total heat budget. However for planets around stars that are closer to the centers of their galaxy, where the concentration of dark matter is significantly higher, just enough heat may be produced by gravitationally captured and annihilated dark matter. The abundance of planets detected by NASA’s satellite mission-Kepler suggests that perhaps life in the universe might be more abundant than we thought.

3- How Much Digital Information Can Mankind Store?

Original Article: Hilbert, H. & López, P., Science 332, 60 (2011).

Have you ever wondered how much total information is stored by human beings? We store information in two different forms: analog storage such as books, printed photos, and audio cassettes, and digital storage such as hard drives, CDs, DVDs, and the like. A recent paper analyzed how the total information storage and processing ability of human beings changed between the years of 1986 and 2007. The study estimated that the total information stored as of 2007 is 295 exabytes. An exabyte is equal to one million terabytes or one billion gigabytes. If all this information was stored on CDs, this stack of CDs would reach beyond the moon. If it was stored in books, it would be enough to cover the entire United States with 13 layers of books. Interestingly, the information stored by DNA in one single human body is about 300 times larger than the entire amount of information stored by humanity. In 2000, only 25 percent of known information was stored in digital form; this ratio increased to 94 percent in 2007. The area in which the “information revolution” is most evident is computation. The study found that the global computing capacity increased by 58 percent per year during this time. But even at this fast rate of growth, in 2007 the total instructions per second that humankind can carry out on its general-purpose computers were about the same as the maximum number of nerve impulses executed by one human brain per second.

4- Tricking the Brain to Attack Alzheimer’s Disease

Original Articles: Atwal, J. K. et al., Science Translational Medicine 3, 84ra43 (2011) & Yu, Y. J. et al., Science Translational Medicine 3, 84ra44 (2011).

Alzheimer’s disease affects many people, especially in later stages of life, and as the lifespan of humans increases, it becomes much more prevalent everyday. The primary cause of Alzheimer’s disease is unknown, but scientists generally associate the disease with the appearance of plaques and tangles in brain cells, often caused by a protein called amyloid. Hence, a natural strategy would be to attack these proteins that form these plaques. Yet, the biggest obstacle in our brain is the blood-brain barrier, which prevents viruses and other unwanted visitors from entering our most delicate organ. Scientists have tried to overcome this barrier with many different drugs and strategies, but there is no clear winner yet. Two recent studies reported in Science Translational Medicine journal give us a new hope in our fight against Alzheimer’s disease. Scientists devised a clever strategy to trick the gatekeepers of the blood-brain barrier into escorting antibodies against the Alzheimer’s-associated proteins. This method reduced the levels of amyloid by up to 50 percent inside mouse brain cells. Designed antibodies had two arms—one arm to target the enzyme, BACE1, which produces the amyloid, and the other arm to bind to the transferring receptor, which in turn deceived the endothelial cells from the blood-brain barrier to internalize the antibody. There are many other brain disorders that we have a limited arsenal against because of the blood-brain barrier. Hence this new method can be used for these diseases, which opens up a whole new venue of targeting strategies.

Adam forgot, so did his children.

How does our brain store information? How is it possible to make learning faster and easier? Is there any way not to forget what we have learned and to remember things more easily? Of what importance is the fact that information is never deleted from our memory, even if we have forgotten it? These are among many of the questions for which answers have been sought over the years.

Memory is one of the functions of the brain and it is defined as the ability to preserve acquired information consciously and relate it to the past. It is not just a certain portion of the brain, but rather the entire organ that functions in storing, processing, and retrieving external and internal signals. Signals that build up our memory are what we usually perceive through our five senses. When we burn our hand, or see or experience a traffic accident , when we are given a compliment and many other events are all examples of external signals, whereas internal signals are related to our nervous system or imagination. The pain one feels during a heart attack, the anxiety of a cold sweat, or a beautiful daydream are all stored in our memory too. We may or may not remember them. There is no deletion; it is simply that we do not remember. Forgetting is a state that is encoded in our makeup with differing degrees, depending on the kind of life the person has experienced. Age, gender, stress, habits, and illnesses all have varying roles in forgetting.

Short-term memory

Short-term memory refers to saving and remembering what we have learned a few seconds or minutes ago; the prefrontal brain is the location for this temporary processing. Signals are kept in this portion of the brain for a few seconds and then conveyed to the back stage (as in the transfer of data from the cache memory to the main memory in computers). We tend to quickly forget those things on which we have not spent a long time or to which we have not assigned great importance, even though we can understand them. Imagine how unbearable our life would be if we were to store in our memories and remember things in infinite detail like the color of the wall we are facing, the variety of the objects around us and their qualities, the air we breathe in and out, or every beat of our heart. The signals that come to our brain within a certain time frame are filtered according to our needs and their significance and limitations are applied depending on their qualities and quantities.

There is no consolidation processing for short term memory. Second or minutes after signals are received they are retrieved in accordance with what we need; if they are insignificant for us, they are forgotten in the same amount of time. The information that is significant for the person is consolidated in the hippocampus and reserved in mid and long-term memory units.

Mid and long term memory

After being processed in the sub-cortex (limbic system) of the brain, signals are saved. Depending on their level of urgency, the meaning they stand for, and their emotional effect, signals are saved in either the mid or long term memory. Pain, joy, pleasure, and fear are states that solidify memory traces. A heart attack, the infliction of wounds and bruises or humiliation, accidents, visits from a loved one-these are all examples of events that are easily remembered. However, a lasting record is almost impossible to attain if the subject is something that has been forced (like a student studying for higher marks) or if the subject does not appeal at all. Consolidation is necessary to make a short term memory a lasting one. However, if a student is curious about the subject and enjoys what he or she is learning, then long term memory is possible without too much effort in consolidation. Forced consolidation (e.g. a student’s orientation to attain higher marks) requires a longer period. The information is consolidated more easily when a person is in a sound and alert state of mind.

Storage in the long-term memory does not occur immediately after something has been learned or experienced. For this storage to be possible at least an hour needs to pass to synthesize the memory proteins that are responsible for recording. If electric shock is applied to a person’s brain immediately after an unforgettable event, they will not be able to remember the event. But if the electric shock is applied an hour later, the memory remains.

Once stored in long-term memory, information can be retrieved, even after months or years. When new information is obtained older information is called up and they are saved with a new pattern of storage, with the newcomers being related with the ones that have already been stored; it is in this way that long term memory is generated.

It has been argued that RNA has a role in storing old information. In experiments, guinea pigs were taught information through repeated practice which is stored in their long term memory. The brains of these animals were later minced up and fed to other animals. It was observed that those animals which had been fed the brains learned faster and more easily than other animals that had been fed on a diet that did not include the brains. This shows us that information encoded in the memory is not lost; rather it is transferred with the help of certain molecules. It is also known that DNA is related to genetic memory.

It has been found that people with good memories have a greater number of nerve cells and channels of transfer in the memory-related zones of their brains (cortex, corpus callosum, hippocampus, thalamus, hypothalamus, limbic system, amygdale, temporal lobe, and prefrontal cortex), while there are less cells in other zones of the brain. Nerve cells are stimulated while signals are stored in one’s memory. Even if a person has a weak memory, activities like reading, memorization, or other engagements that improve love, happiness, and peace of mind may help long-term memory.

Forgetfulness

It is important to find out whether forgetfulness occurs because of an illness or something else. Age is one major factor. Forgetfulness in an aging person is proportionate to the number of the loss of cells.

Stress, dealing with multiple things all at once, or occupying oneself with things that are of no benefit, that is, creating a pollution of information, all affect short term memory and may cause forgetfulness.

Forgetfulness due to damage or illness

If the nerve cells of the lower occipital lobe of the brain are damaged, old information cannot be retrieved. Likewise, in case of damage to the nerve cells that are found in the temporal lobes on the sides of the brain, or due to an insufficient intake of B3 and B12 vitamins, cerebral hemorrhage or an embolism in the veins of the memory zones forgetfulness may occur.

Patients with Alzheimer indicate short term memory loss. They tend to forget visitors’ names, daily events, or the doctor’s advice.

Chronic alcohol abuse may cause damage in the hippocampus and thus in the ability to encode information.

Electroshock may also delete recent information that has been recorded in the short-term memory. Thyroid failure, Parkinson’s, hydrocephaly, schizophrenia, brain tumors, and epilepsy may also cause forgetfulness.

Some advice

Spiritual teachings and religious services have many positive aspects in our lives in addition to being our duties for expressing our servanthood to God Almighty. In Islam, for instance, principles like “enjoining good and forbidding evil,” praying at night, a brief afternoon nap, staying away from what is forbidden, reading and/or memorizing the Qur’an, and other activities may provide some protection against forgetfulness.

It is also claimed that keeping oneself busy with things that are considered morally improper, not least things that are sexually provocative in an illegitimate way, may damage neurons that are operative in memory. In order to be less affected by forgetfulness in our advanced years, it can be helpful to read spiritually and intellectually useful material, to learn and memorize new words and concepts, to keep oneself in good moral condition by engaging in charity work and helping others, and to maintain good sleep and a healthy diet

On the other hand, thinking a bit more wisely, to be able to forget (not forgetfulness) also has many benefits. Our nervous system is relaxed by forgetting, otherwise it might collapse. Forgetting old informa¬tion could well open up room for new information, although this does not mean that the information is deleted from memory; it is retrieved when needed. But, if forgetting reaches a level that is above medically ex¬pected averages, then medical help should be sought.

There are incidents of patients who are suffering from dementia and Alzheimer regaining their memory after electroshock therapy. Perhaps this is evidence that we will remember and testify for all our actions when we will have to account for them.

One of the most important reasons for the last two world wars was the sharing of energy sources. 60 years on from the last world war, the world is now very close to confronting the same problem. There has been an enormous rise in energy demand since the middle of the last century. This increase has resulted from both rapid industrial development and population growth. As shown in Figure 1 and 2, the world population is 4.8 times greater, and the total energy requirement has increased more than 30 fold from between 1850 and 2000. Many studies have demonstrated that while global demand increases by at least 2-3% per year, the current oil fields are depleting at an average of 3-5% per year. If this demand continues at this rate, we will reach a point of crisis in oil sometime after 2010, and the same will be true for natural gas somewhat later, between 2020 and 2030 [1, 3]. The basic energy source of the world, hydrogen, is a new hope for solving the energy problem. It is likely that this century will be the century of the fuel cell. This technology uses hydrogen as fuel, and offers the prospect of supplying the world with clean, sustainable electrical power.

Hydrogen, which is the simplest element in space, was discovered in the 16th century and its inflammable property was understood in the 18th century. Ninety percent of the known universe consists of this simple element. Hydrogen is colorless, odorless, nonpoisonous, and 14.4 times lighter than air. In its liquid phase it has a temperature of -252.77 °C. It is the fuel of the sun and other stars, hence the main energy source of the universe. Hydrogen is not found as a free element in nature, but rather it is found as a compound, particularly as water. Hydrogen has the largest energy amount per unit mass among known fuels. The energy of 1 kg of hydrogen equals 2.1 kg of natural gas and 2.8 kg gasoline. However, its volume per unit energy is higher. It is 1.33 times more efficient compared with fossil fuels as an energy source. When hydrogen is used to produce heat or propulsion, only liquid water or water vapor emerge, making it an extremely clean energy source.

Hydrogen can be used with fuel cells to produce electricity. At the present time, the cost of this method is 3 times more expensive when compared to other fuels. Fuel cells use hydrogen, or hydrogen containing compounds to produce electrical energy and heat. A fuel cell has no moving parts and makes no noise when operating. A single fuel cell contains three layers, as shown in Figure 3. These are the anode-electrode layer, the membrane layer, and the cathode-electrode layer.

There are three types of fuel cells; Polymer Electrolyte Membrane (PEM), Direct Methanol Fuel Cell (DMFC), and Solid Oxide Fuel Cell (SOFC), each named after the material used as fuel. The PEM fuel cell is fueled by pure hydrogen. In the anode, hydrogen is split into its basic elements, a proton and an electron. While the proton migrates through the membrane of the fuel cell, the electron travels around the membrane and goes to the cathode, creating an electrical current. In the cathode-hydrogen proton the electron reacts with oxygen to form water, which is rejected as waste. The basic system is the same for the DMFC and the SOFC fuel cells. The DMFC is fueled by a mixture of methanol and water. Before reaching the anode electrode, the methanol is split into CO²and hydrogen. The SOFC fuel cell can use different kinds of fuels that contain methane and hydrogen. All the reactions are shown in Table 1. One fuel cell can produce 0.6 of a volt. To get enough power, several fuel cells are piled in a stack. The space between fuel cells is filled with gas that helps to distribute the hydrogen and oxygen gas to the membranes.

Although hydrogen energy is a new source, the production of hydrogen is not a new concept. Every year, 500 billion m³ of hydrogen is produced, stored, transported, and utilized in the world. Initially, hydrogen was used for the production of ammonia, but today hydrogen utilization has expanded tremendously to incorporate applications in chemical and petroleum refining, metallurgy, the hydrogenation of edible fats and oils, space and weather programs, fuel cells, and the manufacture of high quality electronic components. The most important consumer is in the petroleum- chemistry industry.

Hydrogen can be obtained by using different methods. Hydrogen can be produced from electricity, using electrolysis to split water into hydrogen and oxygen. Reforming is another method that produces hydrogen. In this method, hydrogen is extracted from a gas with a high concentration of methane, such as natural gas. This process uses hot steam to obtain hydrogen from the methane. When methane gas is mixed with hot water vapor, the gas is split into carbon monoxide and hydrogen.

Although hydrogen can be stored as a gas or liquid, storing and handling hydrogen is difficult as compared to gasoline. While gasoline is a liquid, hydrogen is a gas. At atmospheric pressure at sea level (pressure at sea level is 1.0 atm = 1.01325 bars), hydrogen has a volume 3,100 times greater than gasoline. To decrease the volume of the hydrogen, pressure is used. Hydrogen can be stored under pressure up to 700 bars. At this pressure, hydrogen has a volume 6.4 times greater than that of gasoline.

Another method for storing hydrogen is in the liquid phase. In this phase, hydrogen has a volume 3.6 times greater than gasoline. Liquid hydrogen can be stored under high pressure in steel tubes. Hydrogen should be cooled to -252.77 °C to become liquid. The cooling process requires energy. 25% of hydrogen energy is used for the cooling process. The largest liquid hydrogen tank is at the Kennedy Space Center in Florida. It contains up to 3,400 m³ liquid hydrogen.

Hydrogen can also be stored in metal hydrides. When cooling is applied, the hydrogen atoms diffuse inside the metal hydrides. To release the hydrogen, the reverse process, heating, is needed. Due to the large storage necessary, aluminum and boron hydrides have been used extensively over the last 10 years. In particular, boron hydrides are important as they can be used in liquid conditions. Metal hydride storage is very safe because of the low pressure and the fact that there is little free hydrogen inside the storage tank. Another advantage of this way of storing is that metal hydrides hold hydrogen at very low volumes.

It seems that hydrogen may be the major energy source in the future. Eventually, it will be used to supply the energy needed in the economy, being used for transportation, central and distributed electric power, and combined heat and power for buildings, and industrial processes. However, hydrogen technology is currently in the pre-production stage of development. Hydrogen energy is not cheap when compared to other energy sources at this time. There are some challenges that need to be overcome, such as producing, storing, and using hydrogen efficiently before we use hydrogen instead of fossil fuels. However, hydrogen is the key to solving the energy problems of the world. Hydrogen is available in every country, everywhere. Using hydrogen as an energy source will prevent many conflicts between countries. This energy source will help address concerns about energy security, global climate change, and air quality. It seems that the views of Jules Verne, quoted at the beginning of this article, will be realized one day in the future. And people will thank God not only for water, but also for the hydrogen in it.

References

1. “Energy Wars” by David Chapman – a director of Bullion Management Services the manager of the Millennium BullionFund (www.bmsinc.ca).

2. Cook B., ‘An Introduction to Fuel Cells and Hydrogen Technology’, Heliocentris, 2001.

3. www.un.org

4. www.census.gov

5. www.worldenergy.org

6. www.fuelstore.com

7. www.minihydrogen.dk