Quantum entanglement is an interesting phenomenon. Two or more quantum particles can be linked together in a special way; this makes them behave like one entity. A change in one of the constituent particles can instantly be observed in the other, independent of the distance between the particles. This phenomenon was called “entanglement” by the Austrian physicist Erwin Schrödinger. The basics of quantum entanglement (1) and quantum computers (2) are discussed in recent articles in The Fountain magazine. Some physicists (3, 4, 5) explain this phenomenon by suggesting that the two entangled particles are actually a single particle that can be observed from two different locations in the universe at the same time point, as if they have been created to appear as a pair. At the quantum level, the definitions of space and time become obscure. An atom can be in two distant locations at the same time, but this may not be the case for a paper clip. What about dozens or thousands of atoms? Where is the line between atoms and a paper clip?

Entanglement has already been experimented on atoms (6) and observed in biological systems at room temperatures. A recent study (7) found the first evidence of biological organisms showing strange quantum behaviors. Researchers from UC Berkeley believe that they have observed quantum entanglement occurring in photosynthesis. The possibility of using these molecules for quantum information processing at room temperature may open the doors for photosynthetic quantum computers. This finding could lead to solar cells that are more efficient than today’s photovoltaic cells.

Quantum entanglement has many areas of application, including secure encryption (8), ultra-fast quantum computers (9), ghost imaging (10), teleportation (11), and perhaps the most interesting one, telepathy (12). Telepathy is described as the transfer of thought or feeling from one person to another without using known channels of communication. Fredric W. H. Myers, founder of the Society for Psychical Research, coined the term, telepathy, in 1882 to replace the earlier expression thought-transference. Telepathy is one of the main branches of parapsychological research, and has been studied to try to detect, understand, and utilize phenomena (13). It is often accepted that there is a connection between telepathy and other paranormal phenomena, such as precognition, clairvoyance and empathy. The existence of telepathy has been confirmed through many scientific experiments (12). However there is no accepted mechanism that explains how telepathy works. It remains controversial and is not widely accepted by scientists.

It is always appealing to perceive a phenomenon as happening from nothing or without a cause, as often happens in movies or dreams. But is this realistic? There are many mechanisms, structures, and reactions we can observe in nature which cannot be understood with our current knowledge. One can quickly make a list of things that cannot be explained by science today. It is believed that there is a cause and effect relation, and a reasonable explanation for everything in this universe. Some will push this further to offer an incredible prize for an opposite claim. The JREF (James Randi Educational Foundation) has offered a one-million-dollar prize (14) to the person who can show (under proper experimental conditions) evidence of any paranormal or supernatural event. They will remove telepathy from the list of supernatural events if it can be achieved during a controlled experiment.

Some researchers claim that there is a connection between quantum theory and telepathy. One theory is that the human mind has abilities that influence and receive “quantum fluctuations” from other minds. Another theory explains this instantaneous communication with quantum entanglement. Gao Shen, at the Institute of Quantum Physics in Beijing, China, has conducted experiments (12) to understand this connection by monitoring synchronous EEG patterns between two hypothetically “entangled” minds.

There are many natural events in our daily life that might seem like telepathy. You might hear something from one of your friends or relatives, for example, that they can perceive a phenomenon like an injury or illness to a close person from a distance. Many people claim that they have this kind of experience, especially twins with one another, or mothers and children. Are all these people in close relationships-twins, couples, siblings, parent and child-also sharing quantum entangled particles?

Humans are not the only subjects that show telepathic properties. It has reported (15) that intact double-stranded DNA has an ability to recognize similarities in other DNA strands. This recognition occurs between sequences of several hundred nucleotides without physical contact or the presence of proteins. The way they identify one another and combine chemically is not fully understood. This behavior can be observed in water that contains no proteins or other material that could interfere with the reaction. There needs to be some sort of communication, attraction or guidance between individual DNA strands to explain this behavior. Do these DNA strands communicate through entangled particles?

Could this telepathic behavior of DNA be the explanation of the power of extra sensory perception between people close to each other? Are we all entangled with one another with invisible bonds, existing since the time of Adam and Eve? Is it all because of the genetic inheritance in our DNA? Do our actions affect others, even if we have no direct connection or relation to them? Maybe all the living things and our lives in this universe are a part of a single mechanism, guided and connected in a special way we cannot understand with our current scientific knowledge.

Einstein pointed (16) out the illusion of separateness: “A human being is part of the whole, called by us ‘Universe’; a part limited in time and space. He experiences himself, his thoughts and feelings as someone separated from the rest’a kind of optical delusion of his consciousness. This delusion is a kind of prison for us, restricting us to our personal desires and to affection for a few persons nearest to us. Our task must be to free ourselves from this prison by widening our circle of compassion to embrace all living creatures and the whole of nature in its beauty.”

All these intriguing features of the quantum world can promise new ways of communication, including telepathy. Recent developments in quantum physics, observing entanglement in atoms and biological systems, mysterious communication between DNA strands, and telepathic connection between humans are all pieces of an unsolved puzzle. When we think about how we perceive this world with our known physical senses, and how it might be with other unknown perspectives, we can then wonder what percentage of things in our universe we have not been able to see or know. There is a long way to go before understanding the universe with our limited perspectives and physical senses.

Acknowledgment: This article was produced in MERGEOUS (17), an online article and project development service for authors and publishers dedicated to the advancement of technologies in the merging realm of science and religion.

References

(1) S. Candaroglu, “Quantum Entanglement: Illusion or Reality?”. Fountain, Issue 61 January – February, 2008.

(2) O. D. Ikramoglu, “Quantum-Inspired World of Computers: Science or Fiction?”. Fountain, Issue 74, March – April, 2010.

(3) M. A. Nielsen and I. L. Chuang, Quantum Information and Quantum Computing (Cambridge U. Press, 2000).

(4) Ryszard Horodecki, Pawe Horodecki, Micha Horodecki, Karol Horodecki, Rev. Mod. Phys. 81, 865-942 (2009).

(5) M. Genovese, Cosmology and entanglement, Adv. Sci. Lett. 2, 303-309 (2009).

(6) S. Olmschenk, D.N. Matsukevich, P. Maunz, D. Hayes, L. M. Duan, C. Monroe, “Quantum Teleportation Between Distant Matter Qubits”. Science, 323, 5913, 486-489, 2009.

(7) M. Sarovar, A. Ishizaki, G. R. Fleming, K. B. Whaley, “Quantum entanglement in photosynthetic light harvesting complexes”. arXiv:0905.3787v1 (quant-ph), 2009.

(8) H. K. Lo, and N. Lutkenhaus, “Quantum Cryptography: from Theory to Practice”. arXiv:quantph/0702202, 2007.

(9) D. P. DiVincenzo, “Quantum Computation”. Science, 270, 5234, 255-261. doi:10.1126/science.270.5234.255, 1995.

(10) M. D’Angelo, Y.H. Kim, S.P. Kulik, Y. Shih, “Identifying entanglement using quantum ghost interference and imaging”, Physical review letters, 2004.

(11) D. Bouwmeester, J.W. Pan, K. Mattle, M. Eibl, H. Weinfurter, A. Zeilinger, “Experimental Quantum Teleportation”. Nature, 390, 6660, 575-579, 1997.

(12) S. Gao, “A Primary Quantum Model of Telepathy”. 2003. (Preprint)

(13) Wikipedia, Telepathy, http://en.wikipedia.org/wiki/Telepathy.

(14) James Randi Educational Foundation, “One Million Dollar Paranormal Challenge”, Available online http://www.randi.org/research/index.html

(15) G. S. Baldwin, N. J. Brooks, R. E. Robson, A. Wynveen, A. Goldar, S. Leikin, J. M. Seddon, and A. A. Kornyshev, “DNA Double Helices Recognize Mutual Sequence Homology in a Protein Free Environment”. The Journal of Physical Chemistry B, 112, 4, 1060-1064, 2008.

(16) Elise’s collection of favorite quotes, http://elise.com/quotes/

(17) Mergeous, Online article and project development service, http://www.mergeous.com/

ENIAC had cost around $500.000 and was capable of 5000 simple operations per second. Today, basic personal computers (PC) cost around $500 with enough processing power to perform millions of operations per second. An average PC is enough in terms of computing power for everyday use like word processing, checking emails, and computer games. However, some areas in scientific research require computers at the frontline of current processing capacity, called Super Computers. Twice a year, the TOP500 project, which started in 1993, ranks and publishes details of the 500 most powerful super computers in the world. The IBM Roadrunner, located at Los Alamos National Laboratory, was announced as the fastest supercomputer in the world as of May 2008.

In computing, “flop” (Floating Point Operations Per Second) is a measure of a computer’s performance which is similar to calculations per second. The IBM Roadrunner had cost $133 million and had a peak performance of 1.7 petaflops, which is around 1.7×1015 operations per second. The Roadrunner was delivered on 21 tractor-trailer trucks to its current location. Supercomputers are an essential component of research in areas like computational biology, fluid dynamics, structural mechanics and cancer research, which requires high computing power.

While computers get faster every year, their computing power is way behind when compared to a human brain. They consume hundreds of times more energy than a brain. It is estimated that a computer will be able to simulate a human brain in seven years, yet we are decades away from expecting a computer that can think like a human and make decisions. The brain is one of the most miraculous parts of the human body, full of mysteries. It works more efficiently than any machine developed in the last 50 years of the computer history.

However, the human brain is not the only body part which has an incredible computing power. In 1994, Leonard M. Adleman, a professor at the University of Southern California, introduced the idea of using DNA (Deoxyribonucleic Acid) to solve computational problems [3]. This idea then led to a new field of science, called DNA Computing, which combines two disciplines, biology and computer science, to build the fastest and smallest computers ever. DNA is known as the blueprint of life, with unique properties such as self-assembly, molecular recognition, minute size and high information density.

Computationally challenging problems have known solutions, but enormous amounts of resources (time and/or cost) are required to find the optimum solution. Some problems, such as optimization, can be solved by generating many possible solutions, and then selecting the optimum one. Standard computing methods can generate or test a possible solution one at a time. On the other hand, parallel computing methods can carry out this process simultaneously for thousands of possible solutions.

Similarly, enzymes can work in parallel for replicating and repairing DNA strands. They can even work on the next strand before the first one is replicated. An enzyme can replicate a DNA strand 500 times in a second, which is equal to 0.001 MIPS (million instructions per second). The computations in DNA can reach to 1014 MIPS, while a modern computer runs at an average of 1000 MIPS. DNA computing is not only faster in processing, but also much more efficient in energy consumption. The energy consumption of a DNA operation (on one strand) is about 1010 times less than the energy consumption of an operation on modern computers.

The Traveling Salesman Problem (TSP) is one of the most studied problems in computational mathematics. Here is an example of the problem: a traveling salesman needs to visit 20 cities once, with predefined starting and ending locations, and certain rules. The complexity of the TSP problems increases exponentially with the number of cities, so problems with only hundreds of cities will take thousands of years to solve by modern computers. If there are 18 factorial possible paths in this problem, it will take 2 whole years for a computer with 100 MIPS of processing power to generate the possible paths and find the correct answer. However, all possible paths can be generated in a very short time by using DNA computing. A simplified version of the Traveling Salesman problem presented by Adleman involves the following scenario:

A salesman wants to visit the cities (Figure 3) Monroe, Gainesville, and Conyers, starting from Athens, and arriving at Atlanta last. Each city should be visited only once. The cities are not fully connected. While some cities are connected to another in one direction, others are connected in both directions. Our objective is to find the shortest route to visit all cities once. The solution for this problem is a travel from Athens -> Gainesville -> Monroe -> Conyers -> Atlanta.

When we convert the problem to a molecular language, each city is coded as a single-stranded DNA molecule with 8 nucleotides. We can think of nucleotides as bytes in computer programming, which will take the value 0 or 1. Nucleotides exist as four bases: adenine (A), thymine (T), guanine (G) and cytosine (C). All cities are coded with eight nucleotides as follows:

City Code

Athens ATGC CATG

Gainesville TCAG GTCA

Monroe GACT TGAC

Conyers CGTA ACGT

Atlanta AGCT TAGC

Connections between two cities are coded with the last 4 nucleotides of the departure city and the first 4 nucleotides of the arrival city. For example, the connection between Athens (ATGCCATG) and Monroe (GACTTGAC) is coded as CATGGACT. The complementary codes for connections (the Watson-Crick complements), where every C is replaced by a G, every G by a C, every A by a T, and every T by an A, and connection codes are given below:

Connection Code Complementary Code

Athens – Gainesville CATG TCAG GTAC AGTC

Athens – Monroe CATG GACT GTAC CTGA

Gainesville – Atlanta GTCA AGCT CAGT TCGA

Gainesville – Monroe GTCA GACT CAGT CTGA

Monroe – Conyers TGAC CGTA ACTG GCAT

Conyers – Atlanta ACGT AGCT TGCA TCGA

Conyers – Monroe ACGT GACT TGCA CTGA

The mixture for performing reactions will include DNA strands and their complements for 5 cities and 7 connections between cities in our example. If an Athens molecule (ATGC CATG) encounters the complement strand of an Athens-Monroe (GTAC CTGA) connection in the mixture, a hydrogen bond will be formed between strands (Figure 4). Other strands will continue forming bonds for valid connections between cities, building a complete travel path with the help of DNA ligase. There needs to be enough copies of each DNA strand to generate all possible travel paths.

ATGC – CATG

| | | |

GTAC – CTGA

Polymerase Chain Reaction (PCR) will be used to make multiple duplicates of DNA strands containing Athens (start) and Atlanta (end) cities. The result of PCR will be the amplification of correct travel from Athens to Atlanta, which makes it easy to separate. PCR is a method by which a few strands of DNA can be copied into millions in a very short amount of time. This also makes PCR a very important method to increase small amounts of DNA found in blood or hair samples, which could be enough to carry out analysis and reveal a person’s identity in forensic science.

Electrophoresis follows the PCR process to sort the resulting paths according to their sizes. Since every city is coded with 8 nucleotides, the correct path should include exactly 40 nucleotides representing a full path for 5 cities. The gel electrophoresis process uses an electric field to separate DNA strands by size as they travel through a gel matrix. The speed of DNA molecules differs by their size, which results in the sorting of the molecules by size. After this step, DNA strands starting with the code of Athens, ending with the code of Atlanta and with a size of 40 nucleotides are separated from the mixture.

The last step will be reading the code and removing the DNA strands that didn’t contain all the cities. Adleman used a common method known as affinity purification for the separation process. Finally, the mixture has the DNA strands with the correct travel path, starting from Athens and arriving to Atlanta, and traveling through every city once. All the laboratory work looks complex for this simple problem, but as a new concept for computing, it is revolutionary. In its ability to perform parallel computations, DNA computing shows great promise over traditional computing approaches.

Data density is another unique advantage of DNA. Billions of DNA strands can be stored in a regular laboratory tube. A DNA strand is composed of bases A, T, C and G spaced evenly, 0.35 nanometers apart from each other. The data density of DNA is around 106 GB (gigabytes) per square inch, which is 100,000 times larger than the data density of today’s storage technologies (7 GB per square inches). Moreover, DNA is a durable and strong molecule; the information stored within it can be kept for thousands of years in the right conditions. In 2008, 80% of the woolly mammoth genome, several thousand years old, has been identified from tufts of frozen woolly mammoth hair [4].

DNA is also created with remarkable mechanisms such as built-in error correction. The double stranded nature of DNA provides a double check on pairing. Error repairing enzymes are always ready to search for anomalies during the DNA replication process. It results ina ratio of one error per billion replications. DNA is located and protected at the center of each cell with a perfect balance. The miraculous architecture of DNA has waited for thousands of years to be understood by humans and be used for the benefit of the world. Further studies on DNA might open new opportunities to help researchers in solving technologically challenging problems.

Acknowledgment: This article was produced at MERGEOUS [5], an online article and project development service for authors and publishers dedicated to the advancement of technologies in the merging realms of science and religion.

Halil I. Demir is a postdoctoral scholar in the area of Informatics, and lives in Iowa.

References

[1] ENIAC, Image Credit: Wikimedia, http://upload.wikimedia.org/wikipedia/commons/4/4e/Eniac.jpg

[2] IBM Roadrunner, Image Credit: Wikimedia,

http://upload.wikimedia.org/wikipedia/commons/c/c7/Roadrunner_supercomputer_HiRes.jpg

[3] Leonard M. Adleman (1994-11-11). “Molecular Computation of Solutions to Combinatorial Problems.” Science, 266 (11): 1021–1024.

[4] Miller, W (et al). 2008. “Sequencing the nuclear genome of the extinct woolly mammoth”, November, Nature.

[5] Mergeous, http://www.mergeous.com