Cancer is a prevalent disease among humans and animals, affecting millions of lives across the globe. It can be caused in a variety of ways and can affect virtually every part of our bodies, ranging from skin cancer caused by prolonged exposure to the sun’s harmful UV rays to lung cancer that results from carcinogenic substances smokers inhale. However, plants do not die of cancer despite sometimes being exposed to the sun for over a thousand years – and they do not use any sunscreens!

Humans and animals who live to a certain age are very likely to get cancer one day. We see this situation mostly in our pets which have been specially bred and protected from predators and diseases. Cancer has become part of our lives and remains a top world health priority. The probability of prostate cancer is roughly 80% in 80-year-olds, 90% in 90-year-olds, and 100% in 100-year-olds. However, these statistics yet again do not apply to trees.

What is cancer?

Cancer is a disease caused by the uncontrolled growth of cells that have become abnormal in a part of the body. These abnormal cells are not foreign invaders that have entered our bodies from outside but are instead our own cells. However, in time, various factors such as radiation, viruses, and chemical substances that they are exposed to cause the accumulation of errors, or mutations, in the genetic codes of cells. Some of them then acquire very different characteristics and become alien to their own body.

With old age, errors arise in the genetic code in an increased rate when our cells divide by copying their own DNA. External factors, such as “free radicals” and various radiations that affect our DNA, play a role in these errors. For young people, when there are too many errors in a cell’s genome, a process called “apoptosis” takes place after which faulty cells die before they can multiply in a potentially cancerous manner and forming a tumor. However, sometimes these accumulated errors cause the cell’s growth process to become stuck in the “on” position, and the cell begins to grow and divide continuously. Cells that emerge with out-of-control divisions ignore the commands coming from the healthy cells of the body, continue to grow and reproduce according to the erroneous commands from the cell’s disrupted genome. This situation lasts until death.

What is a tumor?

Cell growths that result from defective genome proliferation will eventually form a mass called a tumor. Some cells grow very slowly and stop at a certain size after a while and do not spread anymore and are called benign tumors. Masses formed by fast-growing, defective (cancerous) cells are known as malignant tumors. Cells that detach from malignant tumors and grow rapidly can attach to another organ where they will begin to grow again when they enter the bloodstream. The process by which cancerous cells start from a tumor and spread all over the body to different organs is known as metastasis.

Why does this process not happen in plants?

One of the most destructive features of cancer when it enters metastasis is the mobility of malignant cells to varying degrees according to their type. Blood vessels, i.e. the transportation pathways of the circulatory system, act like a highway for cancer cells. As the blood vessels surround the entire body, a single cancerous cell can travel to and settle almost anywhere in the body, from the toes to the head.

Plant cells have a vital feature that is different from human and animal cells. In plants, cells do not change their locations because their cells are surrounded by a very rigid, strong, and impenetrable wall outside of normal plasma membranes. Cell walls are made of cellulose, which constitutes the main substance of plants, and form the wooden structures that ensure the plants stand upright and harden while at the same time locking each cell in place and preventing it from migrating within the organism.

Another important difference that is unique to plants is that they do not have blood circulation in which cells are carried; they have a circulatory system in which only water and food are carried. This system is often used to pump water from the roots to the leaves and to transport organic products such as sugar, which is a product of photosynthesis, from the leaves down. Therefore, there are no blood cells or immune system cells in these carrier channels, which are known as wood and roe tubes (xylem and phloem), in plants.

In addition, animal cells are specifically employed in tissues and organs such as muscle, bone, liver, and skin during embryonic development. Thus, when they divide only new cells of the same type are created. Tumors that occur in animal tissues can metastasize into different tissues and disrupt different organs. We can think of animal and human biology as a very complex system in which each cell, tissue, and organ has a task and purpose. In such a system, all elements work in cooperation for the continuation of life. This system is of a kind of irreducible complexity. A human being cannot live without organs like brain, heart, or lungs, while plants, on the other hand, have fewer simpler internal structures which are not as vital. When plant cells divide, they retain their ability to form new cells of any type. This is called totipotency.

In plants, every necessary structure can be recreated from the few tissues they have. For this reason, a gardener can grow new plants from the roots, branches, or leaf parts of a plant.

Plants are equipped with very powerful antioxidants to protect them from the sun’s harmful rays and mutations that may be caused by radiation. Therefore, tumors can develop only due to bacteria, viruses, fungi, parasites, and insects. For example, in a situation that we can call “information confusion” that occurs when Agrobacterium Tumefaciens bacteria insert some of its DNA into the plant’s DNA, an anomaly occurs in the plant’s genome. Cells that go through a rapid growth process and form tumors are not normally classified as cancer, since they simply remain in that area and cannot be transported elsewhere. Since the tumors cannot spread to the whole plant, they may cause only minor distress at most in a specific area rather than a fatal disease such as cancer. Just as the plant continues to grow around a rock that it encounters, it grows around the tumor as well. The tumor can continue to grow for years, but does not spread to the rest of the plant, meaning there is no metastasis.

In summary, plants can also be cancerous, but a cancerous tumor is not a deadly threat to a plant, as its cells are immobile and do not have vital and complex organs like humans and animals. Thanks to the cellulose walls gifted to the them, plants continue their role in the ecosystem by continuing to grow with healthy cells around the tumor as if nothing had happened.

References

• Luis Villazon. “Can a plant die of cancer?” www.sciencefocus.com/nature/can-a-plant-die-of-cancer
• Sam Westreich. “Do Plants Get Cancer?” medium.com/@westwise/do-plants-get-cancer-60eb435c6d1a
• Stuart Thompson. “Plants couldn’t run away from Chernobyl—but that’s what saved them. Why plants don’t get cancer.” www.popsci.com/chernobyl-plants-radiation-cancer

Washing our hands has become one major way to protect ourselves from Covid-19. However, ablutions have always had a central place in the practices and beliefs of many religious traditions. Christians perform baptism with water, in amounts varying from small sprinkles to larger vessels, to bring about purification, cleanliness, revival, and rebirth. Jesus’ washing the feet of his disciples as narrated in the Gospel makes the washing of feet an important practice in Christianity to promote cleanliness and is still carried out to this day. The Jewish tradition also has many instances of ablution where water is specifically used to promote cleanliness, including washing hands to reclaim or preserve purity and mikveh in which the feet or whole body is immersed in water.

The Islamic ablution, also known as “wudhu,” contains 24 washing movements to be carried out several times a day for the five daily prayers. If performed for all five prayers, it would consist of about 120 repeated actions as Muslims washed parts of their body.

A lover must undertake the required preparation to cleanse and beautify oneself before meeting with their Beloved. Likewise, a believer is required to wash specified parts of their body to stand before God in supplication, as instructed in Chapter Maidah of the Qur’an, verse 6: “O believers, when you stand for prayer, wash your faces, and your hands up to the elbows, and wipe your heads, and wash your feet up to the ankles. If you are unclean, bathe and purify your bodies fully. But if you are ill or in the middle of travelling or … you cannot find water, then take wholesome dust and wipe your faces and hands with that. For God does not wish to burden you, rather He desires to purify you and to complete His blessing and favor upon you so that, perhaps, you may be grateful” [5:6].

The spiritual cleansing that the act of wudhu provides is highlighted by the Prophet Muhammad (pbuh) in numerous hadiths, or prophetic sayings, which has been collected under The Book of Purification. While water literally cleans the face and limbs, with every pure intention to do wudhu, the water droplets that meet the body also wash away the minor sins that were committed by the hands, mouth, face, ears, and feet. The famous hadith that “cleanliness is half of faith” [Sahih Muslim, 223] can be interpreted as applying primarily to doing wudhu in one translation [Wudhu: Fiqh, Rules, Purification and Blessings, Qadri]. Therefore, to perfect the faith, to be cleansed of our mistakes continuously, God has given us a simple mechanism through which to be purified and recalibrated countless times in a day.

Many of us perform this pattern of washing with little thought. It has become a routine that we seldom consider a medical protection that we apply to our body. Besides its effects on the soul, washing also has wonderful effects on the body. Over fourteen hundred years ago, the Prophet (pbuh) advised ablution before going to bed. Interestingly, yoga experts in recent years have also started to encourage the washing of the legs, hands, arms, eyes, and the mouth before sleep with cool water for a deeper undisturbed sleep. This is not surprising considering the relief that comes with the touch of water on a busy day.

Three of our principal systems benefit from wudhu; the circulatory system, the immune system, and the electrostatic balance of the body. In this way, the health benefits from the ritual of washing are threefold…

Circulatory system

The circulatory system is a magnificent circuit of blood vessels between the heart and the tissues that make up every other system of the body. The systemic circulatory system circulates oxygenated blood from the heart to the tissues around the body and back to the heart, whilst the pulmonary circulatory system transports deoxygenated blood to the lungs for detoxification and returns clean blood to the heart. The correct functioning of the blood vessels, which act as wires that connect our major organs, are essential to the efficiency of this circuit. These vessels divide into thinner branches called arterioles which in turn split into smaller capillaries which surround the cells of the body. The vascular resistance generated by blood vessels is overcome by the blood pressure generated by the heart to enable blood flow. Over time (due to ageing, or a diet high in fat), our blood vessels often harden and become constricted meaning that the heart has to work harder to overcome increased vascular resistance to maintain steady blood flow. The vessels in the limbs are the most peripheral to the heart and thus the most vulnerable to the process of hardening and narrowing over a long period.

The application of water in our daily routine “exercises” these blood vessels by alternately contracting and dilating them. Water can act as an agent of temperature gradients, thereby affecting the thermoregulatory response of the cutaneous circulation. When hot, water ensures that vessels in the limbs dilate, and when cold, that they contract. In this way, water ensures the flexibility of vessels distant from the heart, forcing nutrients deposited in tissues as a result of poor circulation back into the bloodstream through a temperature gradient.

Lymphatic system

The lymphatic system, on the other hand, is probably not the first to come to mind when we think of the body’s organ systems. Yet without this quietly working system our cardiovascular system would collapse and our immune system would be impaired. Our lymphatic vessels transport “leaked” blood fluids into our capillaries to prevent the accumulation of fluid in the interstitial spaces and eventual tissue damage. The vessels of the lymphatic system are much thinner than those of the cardiovascular system, ensuring the circulation of white blood cells which have an essential role in protecting the body against invaders and resisting disease. It is this fluid that we see oozing out when we have a cut or wound.

The optimal functioning of this system and its thin vessels, like those of the circulatory system, can be said to be closely linked with the effect of washing. The phagocytes and lymphocytes, which make up the immune system are housed by our lymphoid tissues and organs, are supported by the act of wudhu. The nasopharyngeal region behind the nose leads to the tonsils, which are small masses of lymphoid tissue that trap and remove pathogens that are entering the throat. Washing the mouth and nose three times with every wudhu therefore helps to remove the bacteria that builds up in the region of the body most exposed to the external environment. Moreover, the act of washing both sides of the neck during wudhu stimulates our cervical lymph nodes – a specialized mass of tissue which houses lymphocytes and particularly helps to protect the body by removing bacteria and tumor cells from lymphatic circulation. Our lymphocytes are arguably the most important component of our immune system, patrolling every point of the body many times a day and destroying cancer cells and pathogens along the way. Considering that the act of wudhu enhances the filtration effect of our lymphoid circulation, one can see the blessings that come with the divine command to “wash…and purify your bodies fully….”

Electrostatic balance

Our physiology is also closely related to the electrostatic balance of the body. While many psychosomatic diseases result from electrostatic imbalance, the most pronounced effect of static electricity is exerted on the subcutaneous muscles located under the skin, mitigating their function and inducing the onset of wrinkles which often start in the face. Maintaining the regular habit of washing the skin – particularly the face which is most frequently exposed to ultraviolet radiation – protects the surface and internal layer of our skin cells by constantly dampening the skin surface with clean water. It is a much simpler alternative to spending hundreds and hundreds of dollars on expensive skin care and makeup products to maintain a healthy complexion.

In regards to how wudhu can benefit our electrostatic balance, the part of the verse which sheds light to tayammum, “if you cannot find water, then take wholesome dust and wipe your faces and hands with that” highlights that the water substitute for wudhu significantly reduces static electricity, like water. This is why when wudhu is performed calmly with care, it often leaves one feeling refreshed and discharged.

The Quran is a grand source containing many prescriptions for good health. While every civilized person may wash their face and hands throughout the day, wudhu ensures that cleanliness and a sense of well-being is sustained by virtue of its association with worship. The worth and significance of wudhu is not limited to the medical benefits discussed here. However, for anyone else wondering why taking a pause on a busy day with wudhu feels so rejuvenating, I hope this humble article sheds some light to a grand prescription from among the many medicines revealed in the Qur’an.

Sometimes, your back itches slightly and scratching it at that perfect spot fills you with an odd sense of happiness. Other times, you notice a biting itch on your arm and a chickpea-like redness shows up there. Oh, those mosquitoes! It is rarely likely to catch a mosquito in the act, and sometimes it even feels as if their bites just appear out of thin air. As you scratch the blister to soothe the itchiness, your eyes scan the room to locate its infamous proboscis. You see it on a wall, plump with the blood it sucked from you. You cannot help thinking: Why do their bites always leave so much itching? Or even, what is the purpose of itching at all?

Itching is an unpleasant feeling we perceive by our skin and mucous membranes, and an occasionally uncomfortable and sometimes very excruciating feeling.

Itching, just like pain, is a sensation intrinsic to our body to protect itself [1].  It is the way our skin “talks” to us. Indeed animals, even fish, itch too. When itched, our skin instinctively and in its own tongue tells us, “There is something that bothers me and I want you to push it away from me immediately!” If it was not for itching, we would not notice a spider walking on our arm. We would not be disturbed by lice and scabies mites or even fungi that settled on our skin, and we would not try to protect ourselves from these pests either.

An ordinary scabies patient has an average number of about 15-20 adult scabies mites on their skin. In the case of Norwegian or crusted scabies, which is most commonly observed among the elderly, the bedridden, people with seriously weakened immune systems, or those who are unable to itch themselves sufficiently, there are thousands of parasites under the thick crusts of the skin [2]. Itching accelerates the blood circulation on the itched parts, and tissues virtually prepare to fight infection by the rushing blood cells and substances [3]. Yet, millions of people also suffer from chronic itching and scratch their itches much more than usual. To understand this, we need to set on a journey from our skin to our brain.

Human skin consists of three layers: epidermis, dermis and subcutis (also known as hypodermis). The dermis layer in the middle makes glove-like protrusions upward into the epidermis. At the top of these protrusions are mechanoreceptors and nerve endings that allow our skin to sense stimulus (such as temperature, sharpness, pressure, vibration, pain, or itching) [3]. With these receptors, our skin functions as one of our five sensory organs and more like an “alarm system” of our body against changing conditions outside. This alarm system has been created so perfectly that each component knows exactly what stimulus to detect.

Previously, it was thought that pain and itching were sensed by the same receptors (nociceptors) and that mild stimuli were responsible for itching while strong stimuli were responsible for pain [4]. Yet, a contradiction existed because while pain triggered an avoidance reflex, itching activated the scratching reflex. In recent years, it was discovered that the receptors (pruriceptors) that perceive the itching sensation on the skin are the free boundary terminations of C-fibers with myelin-free, slow conduction velocity extending in the form of tree branches toward the upper layer of the skin. Furthermore, it was found that the skin cells themselves behave like itch receptors [3, 4]. When we receive a stimulus that induces itching, such as a mosquito bite which leaves anticoagulant substances on our skin, the mast cells in the skin tissue spring to defense against those alien substances. This ensues the secretion of the bodily defense system called mediators, substances that are produced and stored by mast cells as precursor for emergency conditions. Histamine is the most known of these substances and is the most important mediator in itching conditions [5]. Histamine binds to receptors found for itself in myelin-free C fibers that are tasked for detecting itching on the skin. If we consider histamine as a key, the lock that it fits into is on the nerve that senses itching. Thus, the itching nerve is stimulated by histamine.

The nerves receiving this stimulus connect to the spinal cord at their respective levels and transfer the message to another nerve. Each of these transfer processes is mediated neurotransmitters. The last message transmitted to the brain through these nerves is assessed by the brain and labeled as “itching” [6]. The brain determines the coordinates of the itching location and orders the scratching action to the related muscle system. A new journey that conveys messages from the brain to the arm muscles ends with scratching. Considering the swift rubbing action when we feel an ant walking on our face and scratch to push it away, we may value how fast and perfect our brain and transmission system work.

It is also rather odd how soothing itching can be despite its initially uncomfortable feeling, almost as if our body is rewarding us for saving it from a threat. There are several reasons for this contradiction. Scratching causes a low-intensity pain on the skin. Pain and itch are positioned on the skin alternately. The transmission of the sensation of pain is prioritized while the transmission of itching is prevented [7]. Consequently, our brain senses the pain and, in response, secretes the hormone called serotonin to soothe the body. Although this makes us feel relaxed for a short time, the brain continues to transmit virtual sense of itching by connecting to the receptors that are located on the spinal cord along the same nerve path with the receptors for serotonin [8]. This condition, which may be termed as a vicious cycle of itching-scratching, unsurprisingly infuriates patients. Scratching the same area on the skin continuously causes the production of new mediators and oversensitivity of itching nerves, which can thus turn itching into a chronic distress. Chronic itching can often result as a complication from skin diseases such as scabies, lice, eczema, fungal diseases, or drug allergies. It can also result from a systemic disease such as chronic renal failure, cholestatic liver diseases, thyroid problems, iron deficiency anemia, blood diseases and, rarely, cancers [7]. Itching in systemic diseases can be triggered by mediators on the skin but also by neurotransmitters in the intermediate pathway. This kind of itching cannot be controlled by drugs called antihistamines which block the histamine pathway. Sometimes the brain will receive false itching alarms due to post-shingles contraindications or nerve damage in the vertebrae. Such episodes of itching need to be addressed to prevent adverse outcomes. At times, the reason an itch can occur can even be psychological when there seems to be no need for an itch. According to research, scratching activates the brain’s reward center which triggers the addiction mechanism. Patients in that case are thrilled as they itch constantly [9].

As doors in this mysterious journey of science are opened one after another, we discover that nothing has been created without a purpose, including apparently discomforting sensations such as itching, which, it turns out, is how our skin communicates with us!

References

1. Arıcan O. Kasintinin patofizyolojisi, klinigi ve tedavisi Turkderm 2005;39(2):88-97
2. Jonston G, Sladden M. 2005 Scabies: diagnosis and treatment BMJ;17;331(7517):619-22
3. Guyton AC, Hall JE. Tıbbi Fizyoloji 10. Baski 2001.p815-42
4. Schmelz M. Itch and pain. Neurosci Biobehav Rev 2010;34(2):171-6
5. Arck P, Raus R. From the Brain-skin connection. Neuroimmunomodulation 2006;13(5-6)347-56
6. Metz M, Stander S. Chronic pruritus pathogenesis clinical aspects and treatment. J Eur Acad Dermatol Veneral 2010;24(11)1249-60
7. Metz M, Grundman S, Stander S. Pruritus: an overview of current concepts. Vet Dermatol 2011;22(2):121-31
8. Chen ZF et all. Descending control of itching transmission by Serotonergic System via 5-HT1A-facilitated GRP-GRPR signaling. Neuron Vol.84(4) Nov.19-2014

9. Chan YH et all. Brain’s Reward Circuits Mediate Itch Relief. A functional MRI Study of Active Scratching. Dec. 2013

Robots continue to advance and develop every year, and these consistent improvements continue to amaze us with how much they physically resemble humans. Even though these robots lack spiritual qualities and function way below the human brain, we still admire these developments, for they lead to even more discoveries and help us understand the miraculous human body even more.

Notwithstanding our medical knowledge that continues to build upon nearly 3,000 years of shared human experience and research, new discoveries about the human body, the magnificent work of God Almighty, continue to increase our admiration.

The discovery of the “Interstitium” and the “Subcapsular Proliferative Foci” in 2018 allow us to develop an even greater appreciation for the complexity of our bodies. They are called the “macro organ” and “micro organ” according to the amount of space that they occupy in our bodies, along with the nicknames “buffer organ” and “control center organ” according to their function. These newly discovered biological structures did not attract much attention earlier because, in accordance with our current understanding, organs are more easily visible structures such as the hands, arms, eyes, nose, kidneys, and lungs that have a certain shape and a set of clearly-defined functions. It is interesting that although these complex structures are so widespread in our bodies, they were not known until recently; they are now considered as organs [1].

The Macro Organ: Interstitium

According to an article published in Scientific Reports on March 27, 2018, the “interstitium” was discovered rather serendipitously by David Corr-Loce and Petros Benias of Mount Sinai Beth Medical Center along with Neil Theise, a pathologist from New York University. The discovery came when these physicians were analyzing a cancer patient’s bile duct. Although they had been conducting the same routine over the years, it was the first time they had the sight of slots between examined tissues. They realized that the interstitium was unnoticed earlier due to the disappearance of interstitial fluid after they had examined the tissue with their usual histological methods. Subsequently, the researchers found that this structure was found not only in the bile duct but also in many other organs.

Specifically located under our skin, these micro-compartments were also found in almost all organ membranes except the intestines, lungs, veins, and muscles in order to form a network around the organs with malleable but sturdy proteins. The interstitium, the entirety of the intercellular spaces filled with liquid, has been defined as the largest organ in the body. Actually, examining cells and tissues has been the subject of histology and cytology science for the last 150 years, and the fluid that fills the tissues and forms a basis for supporting these cells was not new to the medical world. However, its definition as a new organ was a first.

The researchers froze the biopsy tissues obtained from the bile ducts of 12 patients in order to preserve and examine the anatomy of the discovered structure. One of the reasons that this organ exists is because it protects the surrounding organs by acting as a shock-absorber and has an effect similar to that of a car’s bumper. Damage to tissues and internal organs remains minimal when one falls, hits something or is impacted Using a micro-endoscopic camera, the volume of this whole organ was revealed to be about ten liters in an adult human [2].

It was later discovered that the interstitium is also present in the structure of lymph nodes, the most important part of the body’s immune system, and that cancer cells enter the lymphatic system through the interstitium. In this case, the interstitium play a significant role as a passageway, or conduction interface, for spreading cancer cells across the body. In an analogy, this organ is akin to the water in which fish swim, the air that surrounds us, and the soil that borders the roots of trees. In this liquid that rotates the cells and spans on the base where they are positioned, any exchange of substances of body biochemistry is regulated within the required amount and size to provide a good setting to the cells, and the hard mechanical effects that may impact the cells are alleviated and absorbed by this liquid pad.

Each discovery of the interstitium’s features, including its significant contributions in the fight against cancer, reveals more and more about how this great organ aids in intercellular communication.

The Micro Organ: Subcapsular Proliferative Foci

One of the most important features of the immune system is that it has its own “memory.” The cells of the immune system can remember the infections a person has contracted before, and can fight infections before they spread. How quickly the immune system reacts based on memory may vary, for instance depending on the type of infection, but is usually quite rapid. Considering how many bacteria multiply in a matter of seconds, a quick response must be launched to prevent infections from spreading across the body.

Professor Tri Phan of the Garvan Medical Research Institute led the team of researchers that discovered the subcapsular proliferative foci (SPF), a “micro-organ” that appeared in the lymph nodes during an infection. Lymph nodes and lymphoid organs such as tonsils, thymus, and spleen are surrounded by a protective capsule made of connective tissue. This capsule was considered to serve the purpose of a mechanical support only to enclose and protect the lymph nodes. However, recent research has shown that in some areas under this capsule, cells that had been alerted to previous encounters with harmful invasive organisms are gathered. These main subcapsular cells are memory B cells that carry information on how to counter the invasive organisms. Memory B cells also proliferate into plasma cells, which are highly important for producing antibodies. Therefore, when an infection reoccurs in our body the subcapsular proliferative foci act quickly to form the first defensive front to prevent the possible spread of infection.

The purpose of vaccines is to activate the attenuated form of a harmful organism to be stored in the body’s memory as an immune response. If the body comes back into contact with similar bacteria in the future, the immune system will remember how to fight it. The discovery of the sub-capsule foci also revealed that these centers are the home for the memory B cells. If they can unveil the development and training processes of the memory B cells in these slots, scientists can produce vaccines that enhance the memory of the immune system even more quickly and efficiently.

The reason why these structures have not been noticed earlier is due to their emaciation, brief emergence, and disappearance. The sub-capsule proliferation centers presented in the article “Memory B Cells Are Reactivated in Subcapsular Proliferative Foci of Lymph Nodes” published in Nature Communications on August 22, 2018 are defined by some authoritative scientists as the “micro-organ.” According to the findings about this new organ, if our infection-fighting immune system would have activated longer than it currently does, we would easily die. Every minute is very crucial in this struggle. These excellent centers that produce memory cells under the lymph node [3] capsules fight bacteria which can replicate in multitudes every 20–30 minutes during an infection.

Although the world of science has been working with the microscope for about 400 years, these centers that have been embedded in our body since its creation could only be noticed today when the microscope design has reached its technological peak.

There are trillions of bacteria living in the intestinal cavity, skin, and orifices of our body. Some of these are already protective and beneficial, yet others are pathogenic. But they do not make us sick because of B cell production centers. When our immune system is weakened for any reason (such as stress, insomnia, or malnutrition) these bacteria can cause illnesses and meet little resistance. These sub-capsular micro-organisms surrounding the lymph nodes were placed in the most strategic places across the human body to fight infections in the fastest way, while the lymph nodes were placed at locations that are most vulnerable to microbial attack.

Consequently, these discoveries increase our admiration for the palace and magnificent realm called our body. It is likely in the light of this information that the anatomy and histology books may be rewritten and the definitions of organs and tissues may be redefined.

References

• Claire Maldarelli, “Scientists found a new organ, but it might not be what you’re expecting,” Popular Science, 3 April 2018.
• iflscience.com/health-and-medicine/newly-discovered-microorgan-helps-explain-how-vaccine.
• nature.com/articles/s41598-018-23062-6

If you heard that a very destructive creature was in your village, what would you expect this creature to look like? Perhaps a ferocious cat, or a colossal beast that was capable of leveling whole buildings? Such a creature does exist in Africa, except it is a single celled bacterium by the genus Trypanosome, a microscopic creature with the capacity to strike fear into the heart of virtually an entire continent. Living a segment of its life as a parasite in the bloodstream of humans and other mammals, Trypanosome can trigger a lethal neurological disorder in the circulatory system. It has also been found that it is the cause of a serious sleep disorder in humans. The disease can ruin a person’s circadian cycle, cause fevers, and changes in personality. Unfortunately, about 60 million people in 36 of the 52 countries in Africa are at constant risk.

Another significant role in the lifecycle of trypanosomiasis is the tsetse fly, the bacteria’s most common intermediate host, which transports the Trypanosome from one mammalian host to another. Trypanosomiasis is endemic in a large area of approximately 3.8 million sq. mi. in Africa, where both the parasitic disease and the tsetse fly coexist. Moreover, the danger is not limited to humans because it also affects many other mammal species, most notably livestock and horses. Malnutrition often follows as a direct consequence when large swaths of animals are killed by trypanosomiasis, as there will be less meat and dairy to consume.

The trypanosome parasite invites disease for the host mammal by collapsing or neutralizing its immune system. Let us first remember how the immune system works:

The immune system

Every living thing is provided with two things: food and protective systems. Immune system is one of these vital systems. Most immune systems across mammals function in similar ways; Antibodies are produced to destroy toxic substances and antigens on foreign bacteria, fungal cells, or the virus sheath invading the body. These antigens can be found on the infected foreign cells and have a unique shape and structure according to the organism that causes each disease. The immune system binds to the antigens of the foreign organism in the same manner as a key-lock system with its antibodies produced while fighting against the disease, thus neutralizes the invading organism.

Most of the antigens, which reveal the identity of a foreign being, are structures created of proteins, polysaccharides, or protein-based fats. Our immune system has the sensitivity and the capacity to produce an infinitely diverse variety that can discern even quite identical but foreign substances bearing antigenic properties for our body. To draw an analogy, a specific antibody can be produced for each speck of dust on Jupiter. Our immune system is blessed with the ability to synthesize appropriate antibodies by selecting proteins that differ in type or location of one amino acid.

The mechanism of binding of the antibody to the antigen is carried out with effective economy, because each type of antibody is produced specifically against a particular antigen. This mechanism works like a key-lock system, so the body recognizes its own cells and does not attack them. Each antibody produced in the immune system is created in a three-dimensional, one-to-one compatible structure with the antigen that causes it to be produced, and easily recognizes and locates it, binds as the key fits into the lock, and thus renders it harmless by disrupting the chemical structure of the antigen.

Trypanosome and the immune system

The case of trypanosome vs. the immune system is somewhat exceptional. The abovementioned almost universal immunity principle does not work against trypanosome. Even though parasites are constantly exposed to the mammalian immune system in the blood, they constantly change the antigen that forms the surface sheath. They thwart the host’s defense, as if rapidly changing their password so that it can never be guessed. Until the immune system produces new antibodies to bind to new antigens, some of the trypanosomes discard their sheaths and drape themselves in another one. If this condition persists, the immune system of the host cannot cope with the infection and may succumb to it.

This extraordinary phenomenon astonishes the scientific community and many scientists are investigating the molecular structure of antigen diversity extensively in African, European, and US laboratories. These parasites are only 0.015–0.030 mm in size, and its two most notorious species are Trypanosoma rhodesiense and Trypanosoma gambiense, which inflict serious damage on the human body.

Like many other parasitic species, the life cycle of trypanosomes is very complex. In each phase of this life journey, the parasite takes different forms and exhibits different characteristics in such an unusual way that generates curiosity. The life cycle can be summarized as follows: when the tsetse fly bites a disease-bearing mammal, the trypanosomes in the mammal’s blood are sucked up and settle in the middle intestine of the fly. They undergo a series of complex processes including several structural and biochemical changes. After about three weeks, the trypanosomes appear in the fly’s salivary glands in a disease-bearing form. Meanwhile, they are also draped in new surface sheaths.

When the secondary host fly bites a healthy person, the disease-causing trypanosomes enter the blood of the new host. In this new stopover, parasites are transformed into a form in which they can rapidly multiply. First, they wreak havoc in blood vessels and on lymph nodes, causing fever, marks and swelling in the body. At this stage, a constant struggle with the host’s immune system ensues. A likely invasion the patient’s central nervous system by the trypanosomes can cause intense drowsiness, coma, and eventually death.

In years of research on the trypanosomes, the thick surface sheath covering the cell membrane of the parasite was first described in 1965 by Keith Vickerman of the University of Glasgow. Shortly thereafter, different surface sheaths were discovered in different trypanosome clones. In 1968, Richard W. F. Page from the Molteno Parasitic Research Institute in Cambridge analyzed and decoded the isolated antigenic surface proteins from several clones, revealing that each clone had a biochemically different protein. The clarity of these differences suggests that each antigen is expressed by a different gene. In the 1970s, George Cross and his colleagues found evidence supporting Le Page’s proposal. These antigens are now called Variable Surface Glycoproteins (VSG). As a result of subsequent research, the picture became even more clear.

Once the infection has begun, antibodies are formed in the host’s immune system that bind to the variable surface glycoproteins that appear on the surface sheath of the invading parasites. These antibodies kill most of the initial trypanosomes. Yet interestingly, on a few remaining trypanosomes a new sheath to which antibodies cannot bind is built, and the trypanosomes evade the immune system’s grasp. The survivors induce a new population producing new variable surface glycoproteins. This time, the immune system produces new antibodies against these freshly constructed antigens. Meanwhile, the parasitic population grows. Newly produced antibodies are able to kill 99% of new parasites again. However, until that time, the parasitic group constituted by about 1% of the survivors has already changed its sheath. Hence, another population begins to multiply. This process of life being a struggle unfortunately continues until the host mammal dies.

The mechanisms of antigen diversity in trypanosomes are very complex and variable, and the total capacity to produce varieties is not clearly known. Recombinant DNA technology is used to investigate the structure of the genes for producing variable surface glycoproteins, the mechanism of cell membrane binding, and the selection and expression of one of the codes. In addition to the four licensed medicines produced for the treatment of parasitic diseases, new drugs are being developed.

It is astonishing that this tiny window of invisible dimensions has such a huge potential opening to different branches of science. Many such exceptional and precise situations exist in the universe that may showcase contradicting mechanisms with general principles and procedures. Sometimes we may wonder why God creates such harmful parasites. Since we do not know the performance at every point of an entire ecosystem with our insufficient scientific knowledge, limited sensory organs and temporary observation, we tend to see any seemingly harmful being as futile and devoid of wisdom and immediately raise our voices in protest. However, with new discoveries in science, thousands of wise meanings may be extracted from a creature we generally take for granted.

References

Lori Peacock, Simon Cook, Vanessa Ferris, Mick Bailey, Wendy Gibson (2012): The life cycle of Trypanosoma (Nannomonas) congolense in the tsetse fly, Parasites & Vectors, 5:109 www.parasitesandvectors.com/content/5/1/109.

Michael P Barrett, Richard J S Burchmore, August Stich, Julio O Lazzari, Alberto Carlos Frasch, Juan José Cazzulo, Sanjeev Krishna, (2003): The Trypanosomiases, The Lancet, Vol 362, November 1, Pages 1469-1475, www.thelancet.com.

www.cdc.gov/dpdx/trypanosomiasisafrican/index.html

To this day, natural breast milk is still regarded as the best nutritional choice for babies. Recent research on stem cells, genetics, and epigenetics [1] from the last three decades, along with information obtained from studies about childhood and youth and testimonials from organizations that guide health policies worldwide, all support this claim. Modern medicine agrees that breastfeeding is the healthiest, most inexpensive, highest quality, and most appropriate choice for protecting both a mother and baby’s health [2]. The World Health Organization holds breastfeeding as an essential gold standard for the immunological development of a child, starting from the first six months to two years of age [3].

Breastfeeding has many benefits. It strengthens the emotional bond between the mother and her baby. It helps ensure that the baby grows in a healthy manner, by establishing its first feeling of trust; positively effects the baby’s intelligence level; and helps bolster the baby’s immune system.

One of the most studied issues in recent studies is the effect of breast milk on respiratory diseases such as asthma. The effects of breastfeeding on asthma, allergic diseases, and respiratory infections has been a topic of concern for the medical world for at least the last 80 years. Recent studies agree that breast milk has a preventive role against lower respiratory tract infections in infancy (0–2 years). However, there are some complications in these studies. Given the challenges in patient standardization, only food-allergy studies can be standardized. Due to the complexity of the environmental and genetic factors that trigger allergies, it should be considered normal that the effect of breast milk has not yet been fully established to protect against a wide range of allergic diseases, particularly asthma [4].

Asthma is the most common chronic disease in childhood and has a complex structure. It has been on the rise lately, and scientists are scrambling to figure out what is causing this increase as well as the best ways to combat the disease. Asthma can be caused by a wide variety of sources, such as genetics, smoking, microscopic ticks and mites in house dust, allergenics such as grass or pollen, obesity, urban life, air pollution, synthetic nutrition, and imbalance in intestinal flora [5]. In addition, premature birth, low birth weight, a young mother, and early exposure to respiratory infections are factors that increase the risk of asthma [6]. Consequently, it is difficult to independently measure the effect of a single determinant in asthma. In a significant study on 3,963 children in the Netherlands, children were breastfed for at least four months and then followed for up to eight years after birth. The outcomes of the study revealed that breast milk significantly reduced the risk of asthma, independent of other variables. It has been observed that the rate of chronic asthma development decreases as the breastfeeding duration increases [7].

Today, breast milk’s benefits have been proven in protecting babies from respiratory infections both early on and later in life. Breastfeeding provides an emergency line of defense against infectious diseases by helping infants whose immune systems are not yet developed enough to fight infections.

Breastfeeding facilitates a beneficial germ exchange between mothers and babies and helps to develop a strong immune system. Enzymes, hormones, bioactive molecules, and growth factors in breast milk are all extremely vital for babies. These crucial molecules help develop the baby’s immune system by interacting with the proximate elements. Thanks to numerous features in its ingredients, breast milk has a significant role in supporting the baby’s immune system with the development of appropriate microorganisms in the intestine. The strength of the microbial structure in the baby’s intestine depends on the way of delivery, diet, and the variety of foods consumed by the mother. This healthy structure in the intestines is essential for the development of the immune system and for building an increased tolerance to new foods that will be taken orally. In infancy, beneficial microbiota in the intestines starts to develop healthily by breastfeeding in the first four to six months.

A comparative study between the intestinal flora of infants fed with breast milk and formula milk showed that the diversity and density of the desired microorganisms increased in a shorter time and in sufficient amount in the breastfed infants. Today, increased hygiene standards have changed the intestinal flora of infants, especially in Western societies. This, however, has increased the risk of diseases such as asthma [8].

Cytokines (a group of proteins and peptides that allow cells to communicate with each other) in breast milk also serve the development and smooth functioning of the immune system and play an important role in protecting the baby against bacterial infections, wheezing, and allergies. Human milk, especially “first milk,” was found to contain more than 20 cytokines [9]. First milk arrives in the first few hours after birth as a miraculous gift to babies when they are most vulnerable to illnesses and helps to protect against diseases. Ig A antibodies in the first milk also protect against infectious diseases that are commonly experienced in early life, besides obesity, diabetes, and allergic diseases that may come later [10].

Infants fed with ready-made foods have lower amounts and types of bacteria in their intestines than those fed with breast milk, which can consequently increase the risk of eczema and asthma. The issue of delaying foods with high allergy potential, especially when switching to supplementary foods, is still being debated. Some researchers suggest that complementary foods should not be introduced to infants up to 12 months. However, the common opinion is that positive intestinal bacteria that develops with sustained breastfeeding can reduce the risk of allergies to additional foods. Another consensus is that the transition to supplementary foods should not be earlier than six months [11].

As breast milk is the most important food for newborns, mothers should diligently endeavor to complete the suggested period of breastfeeding. Breastfeeding, if continued until the age of two and especially in the first six months, is accepted by international pediatric authorities as the cornerstone of nutrition.

Character formation and breast milk

We are physically and emotionally affected by what we eat or drink. Based on this assumption, it can be argued that breastfeeding might also have an influence on the character formation of babies [12]. Although it has been determined that intelligence and brain development are influenced by the emergence or inhibition of some genetic characters in the baby by epigenetic means, no research based on long-term observations has been conducted. In any case, it would be wise for parents to provide the best food both for themselves and their babies. Inasmuch as they make sure the food is hygienic and natural, they should also be cautious that it is obtained through legitimate means. If, for any reason, the mother’s milk is not enough or is suspended, a milk-mother with necessary qualities may be contracted.

Breastfeeding for two years is prescribed in the Qur’an: “Mothers are to suckle their children for two complete years” (2:233). “We have enjoined on human in respect with his parents: his mother bore him in strain upon strain, and his weaning was in two years” (31:14). Likewise, the Prophet Muhammad, peace be upon him, speaking about his son Ibrahim, who died before he could turn two, said, “He has a milk-mother in Paradise, she will suckle him for his remaining milk, (will complete the term of two years).” (Muslim, Fadail, 63, 2316)

References

1. The inherited and non-genetic changes which occur in the disclosure of genetic information i.e. gene expression, without any no change to the structure of DNA.
2. Ballard O, Morrow AL: Human milk composition: nutrients and bioactive factors. Pediatr Clin North Am, 2013; 60: 49–74.
3. World Health Organization Recommendations on Postnatal Care of the Mother and Newborn. Geneva, WHO, 2013.
4. Matheson M, Allen KJ, Tang MLK: Understanding the evidence for and against the role of breastfeeding in allergy prevention. Clin Exp Allergy, 2012; 42: 827–851.
5. Ding G, Ji R, Bao Y: Risk and protective factors for the development of childhood asthma. Paediatr Resp Rev, 2015; 16: 133–139.
6. Oddy WH, de Klerk NH, Sly PD, Holt PG: The effects of respiratory infections, atopy and breastfeeding on childhood asthma. Eur Respir J, 2002; 19: 899–905.
7. Scholtens S, Wijga AH, Brunekreef B, Kerkhof M, Hoekstra MO, Gerritsen J et al..: Breastfeeding, parental allergy and asthma in children followed for eight years: the PIAMA
8. birth cohort study. Thorax 2009; 64: 604–609.
9. Adlerberth I, Wold AE: Establishment of the gut microbiota in Western infants. Acta Paediatr, 2009; 98: 229–238.
10. Goldman AS, Rudloff HE: Are cytokines in human milk? Adv Exp Med Biol, 1991; 310: 93–97.
11. World Health Organization Recommendations on Postnatal Care of the Mother and Newborn. Geneva, WHO, 2013.
12. World Health Organization: Global Strategy for Infant and Young Child Feeding. Geneva, 2003.
13. Ibrahim Canan, Peygamber’in Sunnetinde Terbiye, Istanbul: Isik Yayinlari, 2014, pp. 95.

We eat, sleep, and go to the bathroom. Yet, we never think about how all these physical needs are processed in the systems of our body when they are functioning normally.

Yes, our bodies are created with perfect systems by which our all kinds of needs are met. The digestive system is one of them. Our intestines are key elements of this system, so much so that asking someone “How are your intestines?” would be as comprehensive as asking “How are you?”

Digestive system

Food is critical to life. A human being can bear hunger for one month at most and can only endure a few days of drought. Thus, eating and drinking is crucial.

Foods as we eat them are not convenient for use by the cells. Food must be broken down into smaller pieces. This process begins in the mouth and ends at the anus, and it is called digestion.

The main task of our stomach and intestines is digestion. The teeth, salivary glands, the tongue, and the gullet – as well as swallowing – are essential secondary elements. Additionally, if the pancreas or liver fall ill, it can paralyze the whole system. While also working with the circulatory system, kidneys have the task of reabsorbing useful substances like glucose, amino acids, and water.

Our digestive system works together with the urinary system and the digestive organs like a factory. How these parts work together is still not fully understood, but more detailed research has been performed and revealed more secrets of the digestive system. By means of every discovery, it is realized that this perfect creation has a more intricate structure than is known.

The brain in the intestine

There are more neurons in our intestines than in our spinal cord and the intestines are created in a way that can move independently from the central nervous system. They have their own nervous system, known as enteric nervous system (ENS), which is also called the “second brain. “Within those yards of tubing lies a complex web of microcircuitry driven by more neurotransmitters and neuromodulators than can be found anywhere else in the peripheral nervous system. These allow the ENS to perform many of its tasks in the absence of central nervous system (CNS) control…” [1]. Thus, “… isolated segments of intestine can independently coordinate propulsive movements and propel content without any neural connections to the brain or spinal cord [2].

The intestines take action when food comes into the stomach. This movement is known as colonic migrating motor complexes (CMMC), and it moves the substances that cannot be digested, like bone and fiber. According to neurophysiologist Nick Spencer et al, “The gut wall contains a complete network of intrinsic nerves capable of propelling contents along the bowel, without any requirement of nerves originating in the brain or spinal cord” [3].

Eat different types of food

70% of our immune system cells are in our intestines. A big part of the approximately 38 trillion bacteria in our body are in our intestines, and they are useful; they have a big role in digesting food. Different groups of bacteria feed on different types of food; so for intestinal flora it is very important to have a variety of food on our table. For the ideal day on a plate Dr. Megan Rossi recommends people should “aim for at least 30 different plant species per week.” “The reason for this is that each plant contains different types of fibres and phytochemicals (the super healthy components of plants) that feed different good bacteria. The more plant variety, the more variety of gut bacteria – which is associated with health and happiness” [4].

Pets in our body

For Dr. Megan Rossi, “microbes are like our pets, so you have to take care of them and feed them” [5].

Of course, germ flora in our body is not just limited to the ones in the intestines. Bacteria, viruses, and fungi in our body are nearly scattered throughout the whole body. These living things produce pellicle on our head skin, irritate the gaps between our toes, live on our skin, are on duty among our teeth, and have ecosystems and assigned positions convenient to them. According to the situation, they keep their living spaces healthy or unhealthy. Although they number 50 trillion, they are approximately 200 grams of our body weight.  

Useful microbes

An average size human adult houses about 10¹² bacteria on the skin, 10¹⁰ in the mouth, and 10¹⁴ in the gastrointestinal tract [6].

These microorganisms are useful microbes with duties in our body. The harmless flora of microbes is generally present on the skin, mouth, teeth, nose, throat, and bowel and genital areas. There isn’t normal flora in internal organs except the large bowel. Internal organs have no microbes. If we look closely, flora is inserted in every part of our body which is dirty and has contact with the outer environment. If it was not for the useful flora, microorganisms causing illness would settle instead. Only intestinal bacteria are permanent microbes which are useful. For example, vitamin K plays a part in a crucial event like blood clotting and is produced in the intestine.

Control your stress

Research has revealed that mental and psychological stress affects the health of the intestines. Serotonin is produced automatically in case of need, and 85% of it is produced in the digestive tract. Stress suppresses the level of serotonin produced. Psychological illnesses are associated with low levels of serotonin.

Studies have shown that relaxing practices like meditation for 15-20 minutes can be good for health and reduce stress. At this point, daily prayers are a kind of therapy. Other ways to stay healthy include: avoiding things like alcohol and caffeine, and sleeping well.

Our body has ways of telling us when it’s not healthy. For instance, we can learn the digestive tract isn’t healthy if we have to use the toilet more than three times a day and fewer than three times a week.

References

1. Gershon, Michael D. “The Enteric Nervous System: A Second Brain.” Pdfs.semanticscholar.org.
2. Spencer et al. 2018. “Identification of a Rhythmic Firing Pattern in the Enteric Nervous System That Generates Rhythmic Electrical Activity in Smooth Muscle.” http://www.jneurosci.org/content/38/24/5507
3. http://www.flinders.edu.au/neuroscience/lab_visceral.html
4. https://www.dailymail.co.uk/femail/article-5543159/Doctor-debunks-myths-surrounding-gut-health-say-surprise-you.html
5. https://navva.org/brazil/health/why-the-bowel-is-considered-our-39-2nd-brain-39-and-other-5-amazing-facts-about-the-organ-news/
6. http://www.textbookofbacteriology.net/normalflora_3.html

“It is He who created the night and the day, and the sun and the moon; all (the celestial bodies) swim along, each in its orbit with its own motion.”  (Quran 21:33)

Almost everyone – depending on his or her age, experience, and education level – is aware of certain facts about nature. We know that the Sun rises in the east and sets in the west; water boils at 100 centigrade; humans have five basic senses; birds can find their way back after migrating thousands of miles; and many more. Likewise, laws of thermodynamics, laws of motion, universal law of gravitation, and laws of planetary motion are among the many tools scientists use to explain how nature and the universe work. In the same context, whether or not we are conscious of it, there is this ubiquitous fact of “revolving, rotating, and circling” in the universe in relation to science, religion, and culture. From the Milky Way, sun, planets, and moons to human eyes, circling is everywhere in the universe. Also, it’s imprinted everywhere in the natural world. Giving examples from scientific, spiritual, and social life, this article aims to inquire the “revolving, rotating, and circling” phenomenon to see if it has any implications for humanity.

Rotation of planets

Earth is one of the eight planets in our solar system, all of which orbit the sun, a giant burning star. We know from astronomy that the sun can fit more than one million Earths inside it. Throughout human history, stargazers have realized that all these planets move in a systematic way. The planets orbit due to the immense gravitational pull generated by the sun. Even though the rate may change, each planet rotates around the sun and on its own axis, an imaginary line running through the center of every planet. Also, there are more than one hundred terrestrial, gas, and dwarf moons that revolve around the planets. Every planet, except Mercury and Venus has at least one moon. For example, the Earth has only one Moon (Luna) which orbits around Earth every 29 days; on the other hand, Jupiter has at least 67 moons such as Ganymede, Callisto, and Europa in orbit around it. In addition, our solar system is swarming with different types of bodies (e.g. comets, meteors, asteroids, and space dust) that rotate around the sun along with Earth. Furthermore, it is believed that the Sun is one of about 200 billion stars (maybe more) just in our galaxy, the Milky Way. Galaxies move and gravitationally pull each other, and they do so while rotating around a center. That is, nothing is truly at rest. (1)

Orbiting an atom

In the 1920s, scientists of quantum mechanics discovered that an atom acts like a small solar system. While planets circle elliptically around the sun, electrons rotate around the atom’s nucleus in diffuse, cloud-like waves; these are known as orbitals since they tell us only the probability of detecting the electron at various places within the atom (Choe 2004). These orbitals can blend together to constitute a clump-like “wave packet” that includes the electrons and does rotate around the nucleus. It looks like this quantum phenomenon seems to support rotation in the universe. (2)

The circulation of blood

Doubtless, the heart is one of the most vital and fascinating organs in the human body. It incessantly pumps fresh blood with necessary nutrients throughout the body so that we can survive. Even though it is as big as your fist, it works like a powerhouse by expanding and contracting 100,000 times each day, pumping approximately five quarts of blood per minute, around 2,000 gallons every day. While the heart beats, it pumps blood through blood vessels in the circulatory system to every area of the human body, which takes about 20 seconds to circulate all over the vascular system. It is reported that the blood travels approximately 12,000 miles per day – nearly half the distance of the Equator (24,902 miles). Blood circulation is vital and fundamental to human life: it not only transfers fresh oxygen and nutrients to organs, but also carries away waste such as carbon dioxide from the organs, which is necessary to maintain a healthy life. (3, 4)

Five stages in the human life cycle

Similar to the cycle of four seasons (spring, summer, fall, and winter) in a year, the human life cycle has five or six different stages (Birth, infancy, childhood, adolescence, and adulthood). Human life begins as a single tiny cell, not bigger than a mustard seed, in a mother’s womb. After nine months, circa 40 weeks of pregnancy, the mother gives birth to a newborn. During the first year of infancy, the baby is entirely dependent on the parents’ care, but babies develop very quickly to independency. Childhood includes a period from age 4 to 13, when children learn to eat with utensils, dress and undress without assistance, make friends, play with other kids, and other things. Adolescence is the when a child develops into an adult, when teenagers undergo a rapid transformation of their bodies known as puberty. After the age 20, the human body reaches peak fitness and fertility by stopping development and growth. As we age in adulthood, it takes our body a longer time to repair itself and we become less efficient in many skills. (5)

Circling and prayer

It looks like that this one important pillar of Islam reminds us of the spinning motion in the universe, atoms, the circulatory system, and the life cycle. According to Islamic scholars, millions of pilgrims circulating the Holy Ka’ba in Mecca represents the deep reverence in Oneness of Almighty God. It is believed that these seven compulsory circumambulations of the Ka’ba (the most sacred site in Islam) include individual and social meanings like solidarity and maintaining unity. One explanation as to why Muslims circle the Holy Ka’ba seven times, is the Qur’anic verse that describes the sky above as of seven layers:

“The seven heavens and the earth and whatever is in them exalt Him. And there is not a thing except that it exalts [God] by His praise, but you do not understand their [way of] exalting. Indeed, He is ever Forbearing and Forgiving” (Al-Isra17:44).

It is known in Islam that the spiritual part of the human being includes seven different souls known as nafs. Therefore, every circumambulation of the Holy Ka’ba is meant to move from one spiritual level to the next in order to reach and complete the final expectation to turn our self (nafs) from meat and bone into a more delicate, sensitive, and loving form of soul, one even superior to the Angels. This act of circling the House of God, the Holy Ka’ba, shows how man is sincerely, spiritually, and lovingly attached to the divine.

Conclusion

The planets circle the sun, electrons circle the nucleus in an atom, blood circles the human body, pilgrims circumambulate Holy Ka’ba, and seasons and life cycles circle. There are many more examples of circling in the universe. Even though we cannot see all of them with the naked eye, the entire cosmos, ranging from invisible particles to the moons, planets, stars, and galaxies, are in rotation. Remember that all these rotations happen in accordance with the laws that govern the nature. There is no free choice in any of it.

People are members of this infinite universe, and, unlike planets, electrons, flowers, and cells, they can reason and decide, since we are blessed with free will. As Muslims circumambulate the House of God, this pulling motion between the Ka’ba and pilgrims escalates divine love by changing spiritual dimensions in a way similar to moths flying and circling a light source. Without doubt, a visit to the House of God is an obligatory and praised pillar of Islam, but I believe that the Merciful God wants us also to circle many other divine values and social qualities to deserve His love, mercy, and grace. As long as we circumambulate these highly valued vital qualities such as prayer, selflessness, charity, affection, forgiveness, respect, love, truth, compassion, modesty, patience, and all other good qualities, they will pull us closer both to each other and to Almighty God. Ignoring circling these divine and social qualities would be as if Earth left its orbit.

References

• https://spaceplace.nasa.gov/review/dr-marc-space/solar-systems-in-galaxy.html
• “A Tiny Solar System After All,” April 7, 2004. Rev. Focus13, 15. https://physics.aps.org/story/v13/st15
• “Amazing Heart Facts” in Arkansas Heart Hospital. https://www.arheart.com/heart-health/amazing-heart-facts/
• Jody Braverman, “The Human Life Cycle Stages” www.livestrong.com
• “Growing Older,” in Dorling Kindersley, findout!

Circular motions are all around us. Some are visible or perceptible, while many are not. In a contemplative piece in this issue, Jacob Hardy, a dear friend, writes about this fantastic phenomenon that permeates the universe: “Circling in the Universe.” From the smallest forms of existence at the atomic level to the giant galaxies in outer space, circular motions define a key dynamic in how the universe functions. One of these motions discussed in Hardy’s piece is the circulation of blood in our body. In what could be described as no less than a miraculous system, blood travels nearly the half the length of the equator, only in our body, in just a single day. Our circulatory system brings fresh oxygen and nutrients to our muscles and organs, while carrying away waste. We are thankful to Dr. Hardy for this contemplative piece, and we pray that his healthy blood circulation enables a quick recovery.

9/11 has been a turning point in world history. It was not only a devastating day for the lives lost and their families, but also for millions of people around the world – not least for those who had devoted their lives to a dialogue of civilizations as opposed to the “clash of civilizations.” Professor Ron Messier was one of those who had been studying and teaching Islam for more than three decades by 2001. Though saddened by a prospect that his life’s work would possibly be wasted, he chose to find a channel of communication for dialogue between Muslims and non-Muslims. And he chose Jesus as the focus of this dialogue, for he knew how important Jesus is to both Christians and Muslims. Professor Messier has written for this issue a brief summation of his book Jesus – One Man, Two Faiths: A Dialogue between Christians and Muslims. His conversations with both Muslims and Christians on Jesus offer interesting perspectives, from which much can be learned.  

Also in this issue is a memoir by Kerri Davidson: “In the Eye.” Her piece is a beautiful reminiscence of how parents and kids communicate with their eyes, exchanging feelings of fear, love, and trust. Davidson narrates how she connected with her parents through eye contact. This connection saw them through experiences as mundane as watching horror movies and as traumatic as surviving natural disasters, from leaving home for college to hospital visits. Her story offers many ups and downs, encapsulating the hope and anxiety that every one of us goes through in our lives.

A rainbow is a celestial marvel stretching across the sky after the rain. Along with its spectacular beauty, a rainbow is also a mathematical miracle. By using the language of mathematics, Ali Kaya shows in detail what rainbows offer us.

Being an academic is not an easy thing. In many countries, it seems you are always between a rock and a hard place when you are in academia. Politics permeate the academic halls, where positions might be assigned or created for political allies. Besides this, as a faculty member your superiors have unrealistic expectations of you, such as excruciating teaching loads and a tough oral exam with professors in your field in order to gain some tenure. In recent years, Turkey has unfortunately been one of the worst cases where all these challenges have become unbearable. Arguably the biggest problem of Turkish academics has been the lack of freedom to become critical intellectual voices in public spheres. Academics’ speeches, actions, and political views have traditionally been monitored and tracked by the Higher Education Council or government appointed University Presidents. After the July 15, 2016 coup however, some academicians’ problems became more of a struggle to stay alive. Why were thousands of academics and tens of thousands of teachers fired and arrested for “taking a part in” a military coup attempt on July 15 in Turkey? I can’t find any rational answers.

The current difficult lives of academics are connected to the societal and historical understanding of authority in Turkey. After the coup d’état in 1980, Turkish society witnessed an era where the state and the government were taken as sacred concepts. A lingering tradition since the ancient Turkish states has been that people would rather avoid advocating for truth and morals when they feared doing so would come back and bite them through the cold force of an authoritarian state. Psychological and even physical lynches could and have happened since the power owners and patriarchs are always positioned to be the identifiers of “transgressors” and dictators of the “consequences.” Few people advocated for human rights. For instance, when a group of academics signed an ‘academics for peace’ declaration in January 2016, over 60 Turkish academicians were fired or punished for “spreading Kurdish terrorist propaganda and undermining the country’s national security.” There was no big public uproar, since anyone objecting to it would be demonized as “terrorist supporters.”

Speaking your mind, expressing your opposition, and writing freely have never been easy for thinkers and academics in autocratic regimes. Unfortunately, Turkey has become one such regime in which critical academics are among those facing collective hatred and punishment for their beliefs and views.

These same arguments were recently used as a social lynch for another group: followers of Fethullah Gülen, a Turkish cleric who lives in Pennsylvania. For the last five years since one the biggest corruption scandals involving cabinet members and President Erdogan’s son broke, each investigation has been shut down by Erdoğan with the accusation towards Gülen followers, aka the Hizmet movement, that they were plotting a coup attempt against the government. What followed was the complete overhauling of the police force and police education institutions with the suspicion that many Gülen followers had “infiltrated” their ranks. After the coup attempt on July 15, 2016, which Erdoğan described as “a gift from God,” he also shut down the military and purged half of all high ranking officers, along with thousands of lower ranking members of military, many of whom are still in jail now. 15 major universities were shut down, along with more than 3,000 other schools and hospitals. In the government sector, from health to judiciary, from education to academia, more than 150,000 lost their jobs and 80,000 were arrested upon accusations of being a member of a so called “terrorist organization” with such “evidence” as using free apps like WhatsApp or Bylock, or having Gülen’s books at home or having an account at a once successful bank: Bank Asya. Many reports of abuse and torture in jails emerged since then, and about 40,000 previously convicted inmates were set free to open up space for Gülen’s followers.[1]

Erdoğan’s regime easily demonizes others who are in the opposition by putting them into the “Gülenist” melting pot. For example, atheist religious history professor Candan Badem was first detained, then released, then fired from his job for belonging to the “FETO” organization, a dysphemism produced by the government for Gülen’s followers. The people in Turkey are silent about the genocidal actions of the government because the government has the power to silence even the journalists. Hysteria is in its peak as my own family tells me I cannot send them money from U.S., call them from U.S., or invite them to U.S., which are all received with suspicion by the government that you may be affiliated with the Gülen movement (Gülen has been a US resident for almost two decades). While there are serious claims that Erdoğan himself might have had a part in the coup to consolidate his power, no one including judges, prosecutors, (who are themselves jailed), or the media (Erdoğan shut down all opposition media and arrested over a hundred journalists) can investigate these claims fully. The judiciary system is also on complete lockdown: it made the news when a judge was arrested during his very own court hearing. On another account, as a judge couple were being arrested, their two children, one of them a toddler, were locked in the house from outside and left home alone until their grandparents arrived from a faraway city late at night and found them hungry and desperate. Of the other kids whose parents were arrested some were taken into state custody in unknown locations and not released to their relatives even though they requested them. A female journalist, Ayşenur Parıldak, reported being sexually harassed and tortured while in custody and being confined to a cell. A left-wing journalist, Aslı Erdoğan, was withheld from taking any medicine or being provided a cardigan despite her multiple serious health issues and cold prison cells. She and other left-wing prisoners got the same accusation. After her release, she is now in exile in Germany, awaiting the outcome of her court case in absentia.[2]

Universities were already struggling with favoritism and unfair practices in Turkey. After the so called coup attempt, all university presidents were called into a national meeting organized by the Director of Higher Education Council (HEC) in Turkey, who threatened them that he would take necessary actions against those who “act slowly” in purging Gülen related academics.[3] This was the start of the public statement and demonstration contest among universities where University Faculty Senates hastily wrote statements shunning the group and calling them FETO (abbreviated for “Fethullah Terrorist Organization”) as directed by pro-Erdoğan media, and walked in groups in the streets protesting FETO, while there was no real evidence, official prosecution, or trial. This public hysteria resulted in thousands of fellow academics being fired without any evidence or due process based simply on the lists of profiling done by Erdoğan’s regime officials. Worse, many unions were asking when these positions would be reposted so “other” citizens could apply. Obviously, again, no one was questioning the ethics of this situation, but rather trying to think of ways to benefit from it, whether by trying to replace them with their own kin, or reporting on others to get them fired. Their attitude was, “If you are not going to bite me, long live the rattlesnake, and bite others as you wish!” As an academic who proudly thinks academics can carry an identity to become the bearers of hard truths, this is especially scary to me; not only did academics in Turkey remain silent about social injustices, but some unscrupulous people helped perpetuate this silence by demonizing a group of colleagues. Of course those people proved their worthiness of being strong allies to the current hierarchical system of university presidents, who follow orders from the Director of HEC, who in turn is reporting to the government. It is obvious that this system cannot produce the next generation of critical thinkers and intellectuals.

Why do I care about this personally? Along with some of my friends, my brother, who is an academic, is currently in jail for an unknown accusation after the coup attempt. His wife, who was an entry level secretary within a small municipality, was the first one to be detained. Police stormed into their house 2 days after he and his wife learned they were fired from their jobs. Since the government increased the detainment period to 30 days we were under a big trauma after they took her, not knowing her whereabouts since no one was allowed to make any contact with her, including any attorneys. Was she being raped or tortured? Was she being beaten severely to get some kind of confession out? What is currently happening is similar to what happened in World War II or the Bosnian War where an entire system to protect basic human rights collapsed along with the judiciary system and sense of justice. Can you imagine the feelings of a helpless husband, mother, or father? Worse, can you imagine them having a 2-year old toddler screaming non-stop after witnessing the shock of his mother violently being taken from her family? Three days had passed when she was in front of the judge and the prosecutor for “being a member of a terrorist organization.” Seeing how fragile her health was, the prosecutor asked for her release. She was united with her son at last. However, those judges and prosecutors were shortly fired for not being ruthless enough to hunt all Gülen followers. We don’t know where she and her son is, since she left her town to avoid the trauma of being separated from her toddler, fearing they may call for her arrest again.

A few days after they released her, my brother was taken into custody. He was a shining star in his work, attending each and every conference in his area of expertise, publishing both Turkish and English articles. Philosophy was his passion. They released him after a few days of detainment and courts. Later, when the prosecutors were changed, they sent out another warrant for his arrest. He immediately turned himself in knowing he had nothing to hide. They seized his computer, all of his digital files, and his phone, and they were never returned. All of his academic work was gone. In the first five days of his arrest, his wife snuggled with his coat, refused to eat anything, and just lay in bed. Their toddler still is under a huge shock, and asks for his dad and does not understand why they had to leave his toys, clothes, and everything else he knew to be home.

Besides being permanently fired from their jobs with no social security, health benefits, and retirement without any due process, these academics are no longer able to be hired by any other company or institution due to official and unofficial orders from the government dehumanizing them. Their children who have terminal diseases got their Medicaid cancelled and denied any services at hospitals. They were left to become homeless, helpless, and hungry. “They will beg us to kill them,” Minister of Economy Nihat Zeybekçi said,[4] while a municipal director of AKP, the ruling party, said: “Let them eat tree roots.”[5]

The collective hatred towards and punishment of all opposition for their beliefs is reminiscent of Jewish genocide under Hitler’s regime. This incredible violation of human rights destroyed Turkish academia, freedom of speech, writing, and research, and caused social fractions and hatred among universities. To all governments and to the international community of academics: We must support the rights of these scholars and not let another genocide happen in Europe in the 21^st century.

[1] www.turkeypurge.com

[2] https://pen.org/advocacy-case/asli-erdogan/

[3] https://tr.sputniknews.com/turkiye/201607191023938783-yok-baskani-universite-feto/

[4] https://www.birgun.net/haber-detay/bakan-zeybekci-gebertin-bizi-diye-yalvaracaklar-122392.html

[5] http://www.hurriyet.com.tr/gundem/ak-parti-il-baskanindan-fetoculere-agac-koku-yesinler-40242531