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	<title>urine &#8211; Fountain Magazine</title>
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		<title>The Impeccable Sanitation of the Blood</title>
		<link>https://fountainmagazine.com/all-issues/2015/issue-105-may-june-2015/the-impeccable-sanitation-of-the-blood-may-june-2015/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Fri, 01 May 2015 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 105 (May - June 2015)]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[concentration]]></category>
		<category><![CDATA[fluid]]></category>
		<category><![CDATA[kidneys]]></category>
		<category><![CDATA[lymphatic]]></category>
		<category><![CDATA[macrophages]]></category>
		<category><![CDATA[microbe]]></category>
		<category><![CDATA[microbes]]></category>
		<category><![CDATA[molecules]]></category>
		<category><![CDATA[occurs]]></category>
		<category><![CDATA[organs]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[single]]></category>
		<category><![CDATA[special]]></category>
		<category><![CDATA[Stem Cells]]></category>
		<category><![CDATA[system]]></category>
		<category><![CDATA[tubule]]></category>
		<category><![CDATA[urine]]></category>
		<category><![CDATA[Urine System]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2015/issue-105-may-june-2015/the-impeccable-sanitation-of-the-blood-may-june-2015/</guid>

					<description><![CDATA[Think of a marvelous machine that consists of pipes, pumps, processors, and plugs. This machine grinds and grates, pumps and pours, moves and maneuvers. It constructs and consumes constantly. Despite all this action and activity, it never rusts or ruptures. I believe most of you know what I’m trying to get at. Yes, this machine [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Think of a marvelous machine that consists of pipes, pumps, processors, and plugs. This machine grinds and grates, pumps and pours, moves and maneuvers. It constructs and consumes constantly. Despite all this action and activity, it never rusts or ruptures. I believe most of you know what I’m trying to get at. Yes, this machine is indeed the human body. The brain, the heart, the lungs, and the kidneys are in a constant state of function. A central player in all these functions is the vital fluid we call blood. It continuously monitors, cleans, nurtures, and balances without wasting anything, and does all these while keeping itself pure and pristine. How does it maintain its constitution and purity without wasting even a single molecule, while carrying out numerous tasks all over the body? This, my friend, is what I will try to explain in this article.</p>
<p><span id="more-1776"></span></p>
<p>One of the processes that occurs in the body is called “inflammation.” Inflammation occurs when a cut into the skin also punctures a blood vessel. This situation directly exposes the blood to the air. Inflammation occurs in a few steps. First, the blood vessels near the wound are expanded (which causes the swelling that we see near the cut) and special proteins called “fibrins” are brought in. These fibrins bind to each other to form a net-like structure. We are all quite familiar with this net, which we call a blood clot. This net stops the bleeding and cuts the interaction between the air and the blood within a few minutes.</p>
<p>Next, it is time to quickly eliminate any foreign objects that got into the tissue. Special immune cells called “macrophages” are sent to the crime scene to clean up. Macrophages are large white blood cells that “eat” microbes and other foreign objects using a process called “phagocytosis.” After the scene is all cleaned up, these macrophages excrete special molecules that induce tissue repair and return the blood flow to normal. An important note here is the specific order of these events. Like every single process in the body, they occur in the most purposeful way possible. What do I mean? I mean that, first the wound is closed urgently; second, macrophages are sent in; third comes the tissue repair. Any other order would have greatly lowered the effectiveness of inflammation. Imagine that the wound is closed after the macrophages are sent in. Then, by the time the macrophages killed all the microbes, twice as many would have entered the scene. The body seems to know every single event beforehand and plans its defense accordingly.</p>
<blockquote>
<p>Our body is perfectly calibrated to keep our blood, the milk of our organ systems, absolutely pristine.</p>
</blockquote>
<p>Let’s say a microbe managed to sneak into the blood before inflammation occurred, and is long gone to another region of the body. Does the microbe win? Unfortunately for the microbe, it has to pass another test. This time the tester is the lymphatic system. The lymphatic system is the sewage system of the body. When the blood transfers its nutrients to the tissue, the fluid goes through the “interstitial area” (the empty space between organs). During this process, some of the fluid stays in this area and starts to accumulate. This is where the lymphatic system kicks in. The lymphatic system consists of many tubes running parallel to the blood vessels and recollects any excess fluid and transports them to the subclavian vein near the neck. This way, excess fluids of the body and all of the molecules in them, are reintroduced into the circulation. If there is a problem with this process, an abnormality called “edema” occurs. Of course, the blood is a very sensitive fluid because it travels through the whole body and seeps into almost every single cell. If a microbe were to get into it, it would easily spread and cause disease. So, the lympatics first does a checkup on the body fluid. This checkup occurs at special nodes in the system called lymph nodes found all over the body. Two of the most famous lymph nodes are the spleen and the tonsils. Within these nodes are lymphocytes, special immune cells that “tag” bacteria and other microbes to be later destroyed by macrophages. Thus, the blood is continuously cleaned and kept safe from harmful microbes.</p>
<p>Last but certainly not the least, the final inspection the blood goes through takes place in the kidneys. The aforementioned two checkpoints prevent the entrance of any foreign materials into the blood, and the elimination of any microbes lucky enough to somehow make it through. So, the only task to be completed is the elimination of excess molecules formed in the metabolism. For example, the blood in the veins (the vessels that carry carbon dioxide formed by the respiration of cells) is carried to the lungs where the carbon dioxide is exhaled. But, a much more precise mechanism comes into play in the kidneys. Blood vessels that come from all around the body form a knot-like structure in the kidney called the “glomerulus.” This knot-like shape increases the surface area of filtration. The blood running from the glomerulus is then filtered into the “Bowman capsule,” which surrounds the glomerulus.</p>
<p>But wait! The sanitation system is not satisfied with this first filtration and “thinks” that the filtrate is not ready to be excreted by the urine. So, a more delicate filtration occurs right after the filtrate enters the “proximal tubule.” While passing through this tubule, essential molecules are immediately reabsorbed into the body. The most valuable of all these molecules is glucose, since it is the main source of energy in the body. The proximal tubule reabsorbs around 98 % of all the glucose, while the distal tubule scouts out the rest. After the tubules are done with the filtration, not a single glucose molecule is left in the urine. As a matter of fact, the presence of even a few glucose molecules in the urine leads to a diagnosis of “renal glycosuria.”</p>
<p>After the proximal tubule, the filtrate goes into the “loop of Henle,” where it is dipped into a high-concentration environment. Water travels passively (without the need for energy) from low-concentration to high-concentration areas. In the loop of Henle, the urine is low-concentration, so water runs back into the body. Thus, any excess water in the urine is effectively and economically reabsorbed. The big machine that consists of the glomerulus, the Bowman capsule, the tubules, and the loop of Henle is called a “nephron.” Everything described above occurs in a single nephron. The average number of nephrons in one kidney is around 1,000,000. The human bladder holds around 150 ml of urine on average. So, each nephron is actually responsible for 0.00015 ml of urine production. The kidneys filter over 1,000 liters of blood each day, so our blood is kept just as we want it. Millions of tiny nephrons work in unison to take in huge amounts of blood and they know exactly what to leave and what to keep, 24 hours a day, 7 days a week.</p>
<p>Our blood is our life source. It is the milk of the organs, and our organs would dry up without it. Believe it or not, our organs are quite picky. If they are to receive anything they don’t like, they will start acting up. In order to keep the organs happy, the three mechanisms mentioned above have to work hard and not make a single mistake. These mechanisms are, of course, also made up of cells. These miniscule cells “know” exactly what their clients on the ends of the body like and don’t like, and prepare the blood composition accordingly. Only one word can describe these wondrous mechanisms: Impeccable.</p>
<p><em>Brian Turk is a medical student from New Jersey. He writes on medicine, health, and biology on a freelance basis.</em></p>
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		<item>
		<title>The Camel: A Monumental Creature</title>
		<link>https://fountainmagazine.com/all-issues/2013/issue-95-september-october-2013/the-camel-a-monumental-creature-september-2013/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sun, 01 Sep 2013 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 95 (September - October 2013)]]></category>
		<category><![CDATA[animals]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[camel]]></category>
		<category><![CDATA[camels]]></category>
		<category><![CDATA[cancer]]></category>
		<category><![CDATA[cells]]></category>
		<category><![CDATA[desert]]></category>
		<category><![CDATA[fat]]></category>
		<category><![CDATA[patients]]></category>
		<category><![CDATA[red]]></category>
		<category><![CDATA[retrieved]]></category>
		<category><![CDATA[sand]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[urine]]></category>
		<category><![CDATA[water]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2013/issue-95-september-october-2013/the-camel-a-monumental-creature-september-2013/</guid>

					<description><![CDATA[The camel is a mighty animal and was historically used for transportation in desert lands; thus, it earned the name “the ship of the desert.” Interestingly, a camel’s gait also resembles the rolling motion of a ship. A camel moves both its legs at the same time on one side of its body. They can [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>The camel is a mighty animal and was historically used for transportation in desert lands; thus, it earned the name “the ship of the desert.” Interestingly, a camel’s gait also resembles the rolling motion of a ship. A camel moves both its legs at the same time on one side of its body. They can travel great distances without needing food or water – from anywhere between a week to a month. . A number of unique properties allow them such endurance. They store their water and energy sources in their humps. Some camels have one (Dromedary) hump and others have two (Bactrian camels). Baby camels are actually born without a hump.</p>
<p><span id="more-1541"></span></p>
<p>Humps store fat and also protect camels’ other tissues from heating due to sun light. It has also been reported that camels’ coats insulate them from heat by reflecting sunlight. This extra fat tissue (about 10-15 kg) provides not only energy in long desert journeys but also water through a biochemical process which leads to the production water molecules (1,111 g of water per 1,000 g of fat converted). It is also noteworthy that sparing a specific part of the body for storing fat and refraining from storage in other tissues provides decreased fat density, thus lessening heat retention due to fat.</p>
<p>Water is scarce in the desert and needs to be stored in large amounts when available. Amazingly, camels can drink up to 150-200 liters of water at once, and yet, after three days, there is no sign of water in their stomachs. Drinking so much water in such a short time could be a problem; this would be like a human drinking 20-40 liters of water in 10 minutes, which would induce water intoxication. The oval shape of camel’s red blood cells, and their ability to swell until double in volume provides plasticity in this situation.</p>
<p>Camels can lose up to 25% of their bodily fluids without showing signs of dehydration. This provides an extra durability against long-term water shortage. For comparison, most mammals can only withstand about 3-4% dehydration; further water loss might lead to cardiac failure due to thickened blood. Another protective property given to camels that allows decreased water loss is that they drop feces that are so dry they can be used as a fuel. For comparison, a dromedary camel loses 2.5 liters of water daily through feces (about just 40-60% water) while cattle lose 20-40 liters.</p>
<p>Camels also regulate sweating in a unique way. Their body temperature does not need to be constant; it can move between 34 and 41 degrees centigrade. They don’t sweat until it is over 40 degrees. These regulations allow them to preserve approximately 5 liters of water per day. A camel’s kidney function is also tightly regulated according to the availability of water. If they don’t drink water for days, urine production is limited to approximately 500g. On the other hand, if water is abundant it could go up to 7 liters. This urine is unusually thick, too – it resembles syrup. Remarkably, camels never run, which would increase transpiration; instead they just amble quickly.</p>
<p>However, dehydration can be still an issue, which will negatively affect the flow of red blood cells. Remarkably, camels have oval red blood cells, which better resist clumping when compared to round, human red blood cells. There are no other mammals with oval red blood cells.</p>
<p>Food is another problem for animals living in the desert, especially for big ones like camels. Interestingly, camels have split lips, which allow them to graze easily. They can eat thorny twigs without any injury. Eating green plants also provide the moisture that they need.</p>
<p>Sand is often a problem, especially during sand storms. Remarkably, camels are equipped with systems that allow them to close theirs nostrils to get protection against wind and sand. In addition, camels have two layers of thick eyelashes, which provide additional protection from the dust. The specific shape of their nostrils allows them to preserve vapor and allows returning it to the body.</p>
<p>Traveling over sand is difficult. Camels are created in a way that allows their four legs to kick in all directions. Remarkably, Camels are equipped with paddy hoofs and two toes to protect them from sinking in the sand and burning of the hot sand. In addition, they have long legs, which keep them further from the hot ground.</p>
<p>Though the modern world seems to have replaced them as a major mode of transportation, they are still widely used in areas such as North Africa.</p>
<p>It seems likely many more remarkable discoveries about camels are on the horizon. Medical researchers are studying how camels function – because these amazing animals might contain a secret which could save human lives.</p>
<h3>Link between excess body fat and cancer</h3>
<p>It is obvious that camels undergo a rapid cycle of fat storage and destruction. They store large amounts of fat – up to 15 kg. The correlation between excess body fat and various cancers in humans has long been known. For instance, a WCRF report recommended maintaining a BMI of 20-25%, and claimed it as one of the key factors can prevent cancer. However, a connection between obesity and cancer at the molecular level remains largely unknown. Intriguingly, a recent study performed at UT Southwestern Medical Center by Dr. Scherer and his colleagues shows how fat cells induce cancer cells to thrive in the breast, or fatty livers.</p>
<p>They showed that fat cells allow the growth of tumors via the secretion of a variety of extracellular factors. One of the fat cells derived extracellular factor, which is found abundantly in unhealthy fat tissue, is endotrophin. What endotrophin does is cause induction of blood vessels, which feeds tumors; as we gain weight, this increases the chance of getting cancer. The inhibition of endotrophin by antibodies in mice with breast cancer had a remarkable reduction on tumor growth and prevented metastasis to other tissues.</p>
<p>Well, if fat is bad and could increase the chance of cancer, and camels store and destroy fat as a survival mechanism, then how do camels manage the increased risk of cancer? Do they also have another remarkable property that lies on the horizon to be discovered? It’s probable there is a mechanism in camels that protects them from such adverse effects of excess fat. If so, how can we benefit from it to solve one of the biggest hurdles to human health? Some researchers might be close to answering these questions.</p>
<h3>Antineoplastons</h3>
<p>An interesting study, started back in 1967 by Dr. Burzynski and colleagues, examined the peptides in the urine samples of healthy and cancerous patients. They have found that cancer patients lacked a significant content of peptides in their urine. This finding led to the hypothesis that there might be a protective mechanism against the formation of cancer in the body through peptides. They identified a specific group of peptides found in the urine, later named Antineoplastons that show anti-cancer properties. A treatment scheme was developed through balancing the antineoplaston deficiency in cancer patients to control the abnormal cellular growth. They have tested both in laboratory and on the various cancer patients, and demonstrated some degree of response, albeit with excessive criticism from the scientific community. The mechanism of action of antineoplaston is proposed as functioning as a molecular switch; this activates tumor suppressors and inactivates oncogenes (drivers of cancer formation). Dr. Burzynski, in his clinic at Houston, TX, is still providing treatments to cancer patients with late stages of cancer using Antineoplastons, and claiming that there are survivals with his approach.</p>
<p>The use of compounds identified in the urine could be considered as a kind of urine therapy, which is used as an alternative treatment to cancer that has been historically practiced for different purposes. This reminds me of the prescription of some Bedouins, who got sick when they came to city. They suggested drinking the milk and urine of freely grazing camels at the city’s outskirts. It has been said that they drank this concoction and grew healthy again. This incidence and historical use of urine therapy suggests that camel’s milk and urine could have unique substances that might be effective in the treatment of diseases, maybe even of cancer. An interesting point here is that the Prophet Muhammad, peace be upon him, specifically ordered to drink from animals that are freely gazing, which is also mentioned in the Qur’an, such as in the miracle of the Prophet Salih with the she-camel about which his community was tried: “[S]o leave her to feed in God’s earth” (11:64). This points to not only the consumption of products from freely grazing animals, which is known to affect their nutrition levels and taste, but also to their increased therapeutic potential.</p>
<p>The Holy Qur’an calls for reflection on the camel specifically. I am little bit disappointed that the Houston Zoo does not have such a monumental animal. Contemplation on the camel provides various lessons on the understanding the Maker and Owner of the worlds and living beings, and the superior techniques used in the makeup of animals that live in the harsh conditions of deserts.</p>
<h3><b>References</b></h3>
<p>• 10 Amazing Facts About Camels. Retrieved from http://news.softpedia.com/news/10-Amazing-Facts-About-Camels-68843.shtml on April, 14, 2013.</p>
<p>• 20 Amazing Facts About Camels. Retrieved from http://www.environmentalgraffiti.com/news-expressive-faces-camels?image=1#mzJyLiKcQPMoM1tD.99 on April, 14, 2013.</p>
<p>• Facts About Camels. Retrieved from http://lifestyle.iloveindia.com/lounge/facts-about-camels-1654.html on April, 14, 2013.</p>
<p>• Camel. Retrieved from http://en.wikipedia.org/wiki/Camel on April, 14, 2013.</p>
<p>• Excess Body Fat Causes Cancer. • The WCRF report, 2007. Retrieved from http://www.medicalnewstoday.com/releases/87350.php on April, 21, 2013.</p>
<p>• Finding – and fighting – the fat that fuels cancer. Retrieved from http://www.utsouthwestern.edu/newsroom/news-releases/year-2013/feb/endotrophin-scherer.html on April, 21, 2013.</p>
<p>• Jiyoung Park and Philipp E. Scherer. Adipocyte-derived endotrophin promotes malignant tumor progression. J Clin Invest. 2012;122(11):4243–4256. doi:10.1172/JCI63930.</p>
<p>• Stanislaw R. Burzynski. The present state of antineoplaston research. Integr Cancer Ther. 2004 Mar;3(1):47-58.</p>
<p>• Urine Therapy. Retrieved from http://en.wikipedia.org/wiki/Urine_therapy on April 22, 2013.</p>
<p>• Ravi: Enes. Tirmizi, Tibb 6, (2043)</p>
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		<item>
		<title>It&#8217;s me Peter, your kidney!</title>
		<link>https://fountainmagazine.com/all-issues/2011/issue-79-january-february-2011/its-me-peter-your-kidney/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Sat, 01 Jan 2011 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 79 (January - February 2011)]]></category>
		<category><![CDATA[activities]]></category>
		<category><![CDATA[amount]]></category>
		<category><![CDATA[balance]]></category>
		<category><![CDATA[bladder]]></category>
		<category><![CDATA[blood]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[give]]></category>
		<category><![CDATA[kidney]]></category>
		<category><![CDATA[liquid]]></category>
		<category><![CDATA[liters]]></category>
		<category><![CDATA[nephrons]]></category>
		<category><![CDATA[organ]]></category>
		<category><![CDATA[salt]]></category>
		<category><![CDATA[salts]]></category>
		<category><![CDATA[See-Think-Believe]]></category>
		<category><![CDATA[stones]]></category>
		<category><![CDATA[substances]]></category>
		<category><![CDATA[urine]]></category>
		<category><![CDATA[water]]></category>
		<category><![CDATA[working]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2011/issue-79-january-february-2011/its-me-peter-your-kidney/</guid>

					<description><![CDATA[Dear Peter, in the earlier issues my friends heart and stomach spoke with you and I patiently waited for my turn. I am located at the waist level to the right of the spine and my twin left kidney on the left, on whose behalf I’m also speaking now. We are truly vital organs to [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>Dear Peter, in the earlier issues my friends heart and stomach spoke with you and I patiently waited for my turn. I am located at the waist level to the right of the spine and my twin left kidney on the left, on whose behalf I’m also speaking now. We are truly vital organs to you. Before you say “each one of you claims that it’s vital,” let me talk a bit first, and then you decide.</p>
<p>Dear Peter, in your body, which is built like a well-functioning factory, I am the most essential sanitary device. As the heart pumps blood to take food and oxygen to all your organs, you obtain the energy you need. But do you ever think about the disposal after so splendid activities are carried out in your body? If you burn a stove, you need to dispose of the smoke and the ashes if you want to keep it working. Likewise, as you burn your calorie intake, you dispose of the smoke (carbon dioxide) with your lungs and the waste with nitrate-poisonous after a certain level of intensity-thanks to my quietly and perfectly working filters. That is, I am an organ which saves your life by removing the poisonous substances in your blood. I do not only filter your blood, but also play a role at controlling the balances of the sensitive levels of water, sugar, amino acids and different minerals in your body. In short, I am a tiny but strategic laboratory.</p>
<p>The acid-base balance in your body and the amount of water and different salts are significant values which concern all of your bodily activities. When their balance is upset, different troubles arise in different units of your bodily mechanism. I am such a blessing, which works so sensitively to adjust the levels of water and mineral salts in your body while you don’t even realize it.</p>
<p>A watery environment is needed for the thousands of biochemical activities taking place in your body. In addition, activities like the contracting of the muscles and transmission of electrical stimuli between your neurons are realized with the presence of a pinch of mineral salt you don’t even give a thought about. Sometimes you sweat due to running or hot weather. The white stains on your shirt are the salts you lose after the water evaporates. When you suffer from diarrhea, you lose salt again, for the salt in the nutrients are thrown out without being absorbed. Especially when little children are concerned, this loss is of vital importance. The transfer between the blood and the liquid in the tissues is mainly realized through the concentration differences which are kept in a certain balance. If your body holds too much water, your tissues swell. You particularly feel it when you press your finger over the flesh near your shins.</p>
<p>Dear Peter, I will not list all of my duties in detail in order not to confuse you. However, let me tell you one more. Since not everyone knows this duty of mine, they just see me as an organ of liquid disposal. But I also take part in controlling the blood production! Surprised? Well, I also have the duty of secreting the hormone which stimulates blood production in the bones. I must always stay alert and maintain this balance in the best way; if you start losing blood, for instance, I must increase the hormone and accelerate blood production.</p>
<p>Yes Peter, I’ve told you about a few of my basic duties, but haven’t told you about how wonderfully designed I am. I am a bean-shaped organ and a single kidney like me weighs 130-160 grams on average. We are approximately 10 grams lighter in female bodies. I am surrounded by a soft but protective membrane. I need 35 grams of daily oxygen supply to survive and I use 13 % of your total body energy.</p>
<p>As an army is made up of individual soldiers, I am like a complex army, and a single soldier of mine is called a “nephron,” which does the real job. Thus, you can see me as a body of nephrons. Millions of these nephrons are brought together to make up one kidney.</p>
<p>A single nephron is a thin tubular structure with closed ends, and its length is about 3-4 cm. So the total length of my nephrons is about 50 km. The cup-like sac at the beginning of a nephron is named the “Bowman’s capsule.” The main artery bringing blood to the kidneys branch into smaller units, and one road leads to every nephron. The knot of capillaries (glomerulus) inside this double-walled capsule is more complicated than any road map you might have seen. The total length of the capillaries is nearly 25 km. The unwelcome substances in the blood are passed to the capsule thanks to blood pressure, and they proceed through the tubule. The total surface area of my tubules is about 20 m2. Within five minutes the whole of your blood passes through us. That is to say, an average of 1.2 liters of blood per minute, and 1800 liters a day are filtered by my nephrons, leaving the toxic substances in me. As this amount of blood (nearly 400 times the normal amount in your body) pass through my tubules and return to the veins they leave behind an average of 180 liters of liquid in me. In this case, you could be supposed to throw out 180 liters of urine a day. However, if you really did that, you would neither be able to find a sufficient supply of water nor salt. Fortunately, Providence granted you the mechanism to absorb back nearly 178.5 liters of this filtered substance. This way, the thickened urine throws out the toxic nitrogen-containing byproducts together with a little amount of water. Therefore, I give you back the substances you need with an amount of 1.5 liters of liquid disposal a day. This reabsorbing is realized in what you call the Henle loop. The cells in the walls of my tubules have neither intellect, nor consciousness, nor any knowledge of physiology; in spite of this, they work as if they were perfectly aware of their duty to adjust the amounts and types the substances to be kept or released. To give you an idea, you can think about the huge dialysis machines your engineers design to fulfill the job my tiny tubules do. You decide which one of us is the perfect work of engineering.</p>
<p>A rich network of veins surround the Heinle loop and the reabsorbed substances are released into the bloodstream. The drops to be disposed of are collected and then passed to your bladder. When the liquid in your bladder amounts to a certain value it tightens the bladder walls. The muscles blocking the way out give way and the urine is disposed of. However, know that the bladder has the capacity to expand as large as 1.5 liters when you cannot find the proper time and place.</p>
<p>Peter, most people take for granted the blessings they enjoy. If you visit the nephrology service in a hospital and talk to the patients waiting to be dialyzed, you understand what I mean better. Do not forget that many people who suffer from kidney failure need that huge machine to filter the whole of their blood and they pray for a kidney suitable for transplantation to be found at once.</p>
<p>Incidentally, thinking of chronic kidney failure recalled various reasons which ruin me: long lasting infections, long-term use of certain medicine, different chemicals like ethylene and mercury, heavy loss of blood, high blood pressure, serious burns, and wrong blood transfers etc. In such cases I can receive irreparable damage.</p>
<p>Another issue which troubles me is the formation of kidney stones. The stones which form owing to failures in different metabolic processes really hurt. When excessive decrease of liquids or increases of salts in the body upset my sensitive balance, some dissolved substances remain, begin to collect, and form stones. These stones hinder urine flow and might cause infections. You may drink water abundantly to prevent these stones. Most importantly do not wait too much before going to the toilet. If you excuse me, I also strongly recommend you to urinate in sitting position; this helps emptying your bladder completely and reduces the risk of kidney stones.</p>
<p>I do my job properly until I lose 90 % of my working capacity. When a considerable part of me loses its capacity, the remaining good part boosts its activity to make up for the loss. When one of our twins are taken out with an operation, the other one does not complain at all; it grows a bit bigger and keeps working.</p>
<p>As the nature of honey depends on the nectars bees collect, the ingredients of the urine I produce depend on what’s in your body. Therefore, a urine analysis tells much in the case of illness. For example, I normally do not release valuable substances like glucose and protein in your blood into the urine, but return them to the bloodstream. As my friends cannot fulfill this function in diabetic patients, their urine analyses reveal glucose. As for medicines, I throw them out right away since they are alien substances to me.</p>
<p>Peter! You are young and healthy but be careful and do not get cold around the waist, otherwise I might trouble you. There’s a lot to tell you Peter, but I do not want to confuse you. Like any other organ, I do not like being taken for granted and I just wish for you to appreciate what a blessing I am. Let me note that my perfect cooperation with the rest of your body is another wonder in itself. Anyway, the urea in your blood is increasing, so I must go help my twin now. Goodbye Peter!</p>
<p><em>Irfan Yilmaz is a professor of biology at Dokuz Eylul University, Izmir.</em></p>
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		<title>Do Not Take Urine for Granted</title>
		<link>https://fountainmagazine.com/all-issues/2005/issue-51-july-september-2005/do-not-take-urine-for-granted/</link>
		
		<dc:creator><![CDATA[Louima Cunningham]]></dc:creator>
		<pubDate>Fri, 01 Jul 2005 00:00:00 +0000</pubDate>
				<category><![CDATA[Issue 51 (July - September 2005)]]></category>
		<category><![CDATA[autonomous]]></category>
		<category><![CDATA[baby]]></category>
		<category><![CDATA[bladder]]></category>
		<category><![CDATA[body]]></category>
		<category><![CDATA[clear]]></category>
		<category><![CDATA[divine]]></category>
		<category><![CDATA[excretion]]></category>
		<category><![CDATA[fetus]]></category>
		<category><![CDATA[fluid]]></category>
		<category><![CDATA[healthy]]></category>
		<category><![CDATA[human]]></category>
		<category><![CDATA[infinite]]></category>
		<category><![CDATA[kidneys]]></category>
		<category><![CDATA[knowledge]]></category>
		<category><![CDATA[metropolis]]></category>
		<category><![CDATA[pressure]]></category>
		<category><![CDATA[Science]]></category>
		<category><![CDATA[system]]></category>
		<category><![CDATA[times]]></category>
		<category><![CDATA[urination]]></category>
		<category><![CDATA[urine]]></category>
		<guid isPermaLink="false">http://107.21.79.195/all-issues/2005/issue-51-july-september-2005/do-not-take-urine-for-granted/</guid>

					<description><![CDATA[The amount of activity that goes on in the human body makes it comparable to a city. There is even more activity in a human body than in the busiest of cities, only all on a smaller scale. Most people are not aware of the highly complicated and orderly processes that take place in their [&#8230;]]]></description>
										<content:encoded><![CDATA[<p>The amount of activity that goes on in the human body makes it comparable to a city. There is even more activity in a human body than in the busiest of cities, only all on a smaller scale. Most people are not aware of the highly complicated and orderly processes that take place in their body; the cause and effect mechanisms that are vital for the human metropolis to function properly all work involuntarily. The processes that occur so that our body can carry out the normal bodily activities of digestion, food transmission to body cells, disposal of waste products, distribution of oxygen to all the cells through respiration and many other activities are all carried out so smoothly that we are never even aware of them. We habitually answer a call of nature, never giving thought to the various-small or great-systems that are present, from the warning signal and our response to it, to the relieving process that all work in perfect harmony.</p>
<p>Nephrology is the study of the kidneys, the essential organ of excretion, and elements related to it. If due observation and research are thoroughly carried out on every part of the human metropolis, when the integrated hierarchical mechanisms are analyzed, it can be seen that numerous events are constantly taking place; these can open new doors to various sciences and offer us new horizons of reflection on the Divine Wisdom. In this way, these events are an interpretation of the saying “If all the seas were to be made up of ink, and all the trees were pens, they would still not be able to write down the knowledge of God,” which points to the existence of an Omnipotent Being with infinite knowledge.</p>
<p>One of these constant activities in our body is the excretion system which works like a well-regulated clock. In the body of a healthy adult, the bladder, after an accumulation of urine that has been filtered through the kidneys, resembles a balloon that has been inflated. The bladder enlarges according with the amount of urine that has been filtered by the kidneys. The autonomous nervous system has a significant role in the wonderful functioning of this urine storage mechanism. If we assume that an average adult urinates 5-6 times a day, we can say that the average time adults spend for urination is about 5 minutes daily. The autonomous system of a baby however, is not properly developed and has a very limited capacity of urine storage. Therefore, the bladder of a baby is frequently emptied. As for newborn babies, the number of times that they empty their bladder can be as much as 20-25 times a day. In this way, both the urine that comes from the kidneys flows to the bladder freely, and the urination channels are automatically cleaned.</p>
<p>In order to allow the urine flowing from the kidneys to the bladder to pass freely through the small tubes that measure between 3-7 mm (the urethra) the inner pressure in the bladder needs to be kept at low levels. This is realized in the body of a baby by the frequent emptying of the bladder, until the autonomous nervous system has properly developed. After the sixth month, the autonomous nervous system develops, the urine storing capacity of the bladder increases, and the number of urination times decreases. As the child grows, the ability to store urine and to excrete it at the proper time and place is completed in a gradual process. Being only one of the hundreds of wonders in the human metropolis, this balance is maintained as a clear reflection of Divine Mercy.</p>
<h3><b>Cooperation in the urinary tract </b></h3>
<p>There is a fascinating cooperation between the departments of this metropolis. The urine that is excreted by the kidneys does an excellent job of cleaning all along the urinary tract, like a river cleaning the stones over which it passes. This cleaning includes not only any microorganisms, but also any gravel which might form in the urination channels. Research has proved that when bacteria are injected into the bladders of healthy people no infection is developed in the urinary tract, since the pressure of their urine excretion drives the bacteria away. The protection of the kidneys by both the expansion of the flexible bladder wall and the decrease in the pressure inside the bladder is a good example of the cooperation between the kidneys and the bladder. If the pressure was not able to be decreased by such flexibility, the kidneys could not function under the resulting high pressure. The smooth functioning of the kidneys is maintained through urine excretion in suitable amounts and at a suitable pressure. Taking all this for granted, one usually comes to realize what a blessing the excretion system is only when there is a problem.</p>
<h3><b>The urination of a baby in the womb</b></h3>
<p>The placenta has the duty of being the main regulator of the feeding and excretion systems of a fetus. The kidneys of a fetus also play significant roles. For instance, they balance acidity through liquid electrolytes, carry out the functions of hormone production, and growth. From the fourth month on, the fetus begins to produce urine and the bladder is filled and emptied every 30-60 minutes. The urine inside the bladder is emptied into the amniotic fluid which surrounds the fetus like a protective pad. The duty of the amniotic fluid includes protecting the fetus against the changes in the mother’s body temperature, providing space for normal development, providing suitable conditions for food and oxygen supply, and protecting the baby against any possible blows that the mother’s belly might be exposed to. The amniotic fluid in which a baby is placed is a liquid similar to urine, and it is produced for the comfort of this new guest to our world.</p>
<h3><b>The formation of urine</b></h3>
<p>The blood, which is charged with transmitting nutrients and oxygen even to the remotest parts of the body, brings the toxic disposal our body has produced due to various causes on its way back to the kidneys. The blood, which bears the responsibility of maintaining the health of metropolis of the body, is continuously filtered when it reaches the kidneys. In the kidneys, the waste material is so delicately separated that it as if the kidneys know “which substance is needed in what amounts,” without meticulous calculation and infinite knowledge. Artificial kidneys supported by latest technology (like modern devices of dialysis) are never a substitute for a real kidney. A healthy kidney, which is made to serve under the veil of causes created by the Owner of infinite knowledge and power, does its duty with divine guidance. It sends what is to be disposed of to the bladder in the form of urine.</p>
<p>The substances urine contains are used when diagnosing illnesses, for they possess different qualities. The color, smell, and density of the urine and the substances it contains give us various clues about the health of that person. Deviations in the sensitive balance established in the excretion system are considered to be a sign of something gone wrong in the human metropolis. In other words, a urine analysis is an important indication of health, for many factors, such as our lifestyle, our eating habits, disease, and the medicines we use can effect changes on the consistency and composition of the urine (figure 1-3). The urine of a healthy person is yellow and clear. This color is derived from the urochrome pigment along with urobilin and uroerythrin. Colorless urine can be seen if there has been recent fluid consumption, or the use of diuretics, or disorders such as different types of diabetes (diabetes mellitus, diabetes insipitus, etc). The color of urine can fluctuate between yellow and clear within the day (for example, 1-2 hours after a meal it can be clear, whereas it can turn to dark orange due when one has been making heavy effort). Beetroot, artificial colorings and some drugs can turn the urine red. When the complaints of a patient are taken together with a medical examination and lab analyses, urine samples which are colored red-brown, blue-grey, milky-white or which are cloudy may all be symptoms of disease.</p>
<p>As we learn new things about urine we will hopefully attain a deeper comprehension of the infinite divine blessings that have been bestowed upon us, offering thanks to our Creator from new perspectives. </p>
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